Aliases for CDIPT Gene
External Ids for CDIPT Gene
Previous GeneCards Identifiers for CDIPT Gene
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
GeneCards Summary for CDIPT Gene
CDIPT (CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase) is a Protein Coding gene. Diseases associated with CDIPT include fibromuscular dysplasia. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include carbohydrate binding and diacylglycerol binding.
UniProtKB/Swiss-Prot for CDIPT Gene
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.