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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDHR1 Gene

protein-coding   GIFtS: 54
GCID: GC10P085954

cadherin-related family member 1

(Previous name: protocadherin 21 )
(Previous symbol: PCDH21)
 Explore 10 diseases affiliated with
CDHR1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CDHR1    

Aliases
for CDHR1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cadherin-Related Family Member 11 2     Protocadherin 211
PCDH211 2 3 5     MT-Protocadherin1
PRCAD2 3 5     RP652
KIAA17751 3     Protocadherin-213
Photoreceptor Cadherin2 3     Protocadherin-213
CORD152 5     PrCAD1

External Ids:    HGNC: 145501   Entrez Gene: 922112   Ensembl: ENSG000001486007   OMIM: 6095025   UniProtKB: Q96JP93   

Export aliases for CDHR1 gene to outside databases

Previous GC identifer: GC10P079799


Summaries
for CDHR1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CDHR1:
This gene is a member of the cadherin superfamily of calcium-dependent cell-cell adhesion molecules. This non-classical
cadherin appears to be exclusively expressed in the mitral and tufted cells in the main and accessory olfactory bulbs
of the brain, suggesting a possible role in the formation and maintenance of neuronal networks. Alternatively spliced
transcript variants encoding different isoform have been identified. (provided by RefSeq, Jan 2010)

UniProtKB/Swiss-Prot: CDHR1_HUMAN, Q96JP9
Function: Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer
segment (OS) of photoreceptor cells (By similarity)




Genomic Views
for CDHR1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CDHR1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CDHR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDHR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDHR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.1   Ensembl cytogenetic band:  10q23.1   HGNC cytogenetic band: 10q23.1

CDHR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDHR1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P085954:  view genomic region     (about GC identifiers)

Start:
 85,954,410 bp from pter      End:
 85,979,377 bp from pter
Size:
 24,968 bases      Orientation:
 plus strand

Proteins
for CDHR1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CDHR1_HUMAN, Q96JP9 (See protein sequence)
Recommended Name: Cadherin-related family member 1 precursor  
Size: 859 amino acids; 93595 Da
Subunit: Interacts with PROM1
Subcellular location: Cell membrane; Single-pass membrane protein (By similarity). Note=Localized at the junction
between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized
on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal
day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin
between postnatal days 2 and 9 at the base of the growing OS region (By similarity)
Secondary accessions: Q69YZ8 Q8IXY5
Alternative splicing: 2 isoforms:  Q96JP9-1   Q96JP9-2   

Explore the universe of human proteins at neXtProt for CDHR1: NX_Q96JP9

Post-translational modifications:

  • Undergoes proteolytic cleavage; produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal
    • fragment (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96JP9

    • CDHR1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001165442.1  NP_149091.1  

    ENSEMBL proteins: 
     ENSP00000331063   ENSP00000361189   ENSP00000415980  

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    Uscn Proteins for CDHR1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane ----
    GO:0005887integral to plasma membrane IEA--
    GO:0016021integral to membrane ----
    GO:0042622photoreceptor outer segment membrane IEA--


    CDHR1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CDHR1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CDHR1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015919 Cadherin-like
     IPR020894 Cadherin_CS
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry Q96JP9

    ProtoNet protein and cluster: Q96JP9

    1 Blocks protein family: IPB002126 Cadherin

    UniProtKB/Swiss-Prot: CDHR1_HUMAN, Q96JP9
    Similarity: Contains 6 cadherin domains


    Function
    for CDHR1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CDHR1_HUMAN, Q96JP9
    Function: Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer
    segment (OS) of photoreceptor cells (By similarity)

    miRNA
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    hsa-miR-1233 hsa-miR-1294 hsa-miR-637 hsa-miR-4325 hsa-miR-650 hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmid: CDHR1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for CDHR1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDHR1

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----


    CDHR1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CDHR1:
     Decreased Salmonella enterica  

    Animal Models:
         Mouse knock-out Cdhr1tm1Nat for CDHR1
         2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Cdhr1):
     normal  vision/eye 

    CDHR1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CDHR1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDHR1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CDHR1 (Q96JP93 ENSP000003611894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RYKP349253, ENSP000002960844I2D: score=1 STRING: ENSP00000296084
    PROM1ENSP000004154814STRING: ENSP00000415481
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion IEA--
    GO:0009987cellular process ----
    GO:0045494photoreceptor cell maintenance IEA--


    CDHR1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CDHR1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDHR1

    1 HMDB Compound for CDHR1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about CDHR1 

    Transcripts
    for CDHR1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CDHR1 gene (2 alternative transcripts): 
    NM_001171971.1  NM_033100.2  

    Unigene Cluster for CDHR1:

    Cadherin-related family member 1
    Hs.137556  [show with all ESTs]
    Unigene Representative Sequence: NM_033100
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332904(uc001kcw.3) ENST00000372117(uc001kcv.3 uc009xst.3)
    ENST00000459673(uc001kcx.3) ENST00000440770

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate CDHR1:
    hsa-miR-1233 hsa-miR-1294 hsa-miR-637 hsa-miR-4325 hsa-miR-650 hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmid: CDHR1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: CDHR1
    OriGene siRNA: CDHR1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDHR1
    Clone
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    Additional cDNA sequence: 

    AB053448.1 AB593154.1 AB593155.1 AK124752.1 BC038799.1 

    6 DOTS entries:

    DT.209750  DT.100751041  DT.100751040  DT.91801790  DT.95069816  DT.92411371 

    24/103 AceView cDNA sequences (see all 103):

    BM799943 BM694843 BM717383 T34854 BM697279 BU736793 BQ437325 Z43499 
    BQ638297 BM703573 BQ639936 BU181921 CA488572 BU734477 NM_033100 BM705215 
    BC038799 CA450316 AI460035 AW295888 BM722755 BX281126 BM693111 T34841 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CDHR1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ^ 18
    SP1:                                                                                                              -           -     -     -         
    SP2:                                                                                                              -                                 
    SP3:                                                                                            -                 -                                 
    SP4:                                            -     -     -                                                                                       
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for CDHR1

    Expression
    for CDHR1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDHR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GACAATAAAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CDHR1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Skeletal MuscleExtraocular MusclesSkeletal Muscle
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)Intermediate Mesoderm, Kidney

    See CDHR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDHR1

    SOURCE GeneReport for Unigene cluster: Hs.137556
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    In Situ
    Assay Products:     
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    Orthologs
    for CDHR1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CDHR1 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CDHR11 cadherin-related family member 1 70.19(n)
    71.06(a)    		   414847  NM_001001759.1  NP_001001759.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CDHR16
    		 --
    		 67(a)
    		 1 ↔ 1
    		 GL343199.1(3174952-3254583)
    African clawed frog
    (Xenopus laevis)    		 Amphibia AW159202.12   -- 80.04(n)    AW159202.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.110652 Transcribed sequence with weak similarity to protein more 73.97(n)    BG307082.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Cad74A6
    Cad87A6
    		 Cad87A
    		 8(a)
    7(a)
    		 possible ortholog
    possible ortholog
    		 3L(17360853-17372630)
    3R(7719234-7774851)
    worm
    (Caenorhabditis elegans)    		 Secernentea cdh-36
    		 Cadherin-3
    		 4(a)
    		 possible ortholog
    		 III(7741208-7754383)


    ENSEMBL Gene Tree for CDHR1 (if available)
    TreeFam Gene Tree for CDHR1 (if available) 

    Paralogs
    for CDHR1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDHR1 gene
    CDH232  DCHS12  CDHR22  DCHS22  CELSR32  FAT22  CELSR12  PCDH152  
    FAT32  FAT42  CELSR22  FAT12  
    1 SIMAP similar gene for CDHR1 using alignment to 3 protein entries:     CDHR1_HUMAN (see all proteins):
    CDH23

    CDHR1 for paralogs           About GeneDecksing



    Genomic Variants
    for CDHR1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/612 NCBI SNPs in CDHR1 are shown (see all 612)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs756921411,2
    		F,--79799266(+) AGTGGG/CTCAGC 2 -- us2k11Minor allele frequency- C:0.02WA 118
    rs749560191,2
    		F,--79799486(+) ATCACC/ACTTTC 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1134467471,2
    		--79799525(+) AGAACC/ATGCTT 2 -- us2k12Minor allele frequency- A:0.03CSA WA 120
    rs760412901,2
    		F,--79799527(+) AACCTG/TCTTAG 2 -- us2k11Minor allele frequency- T:0.04NA 120
    rs122421021,2
    		C,--79799662(+) CCAAGA/CCCCAC 2 -- us2k10--------
    rs749037251,2
    		F,--79800119(+) GCTGCG/TCCTCT 4 R L mis11Minor allele frequency- T:0.02EA 120
    rs413086611,2
    		F,--79800691(+) GAGGCG/CGAGCG 2 -- int11Minor allele frequency- C:0.03NA 120
    rs115923611,2
    		C,F,H,--79800999(+) TGCTGC/TGCGCG 2 -- int16Minor allele frequency- T:0.13NA CSA EA 250
    rs767196401,2
    		C,F,--79801187(+) CAAATG/ATATTT 2 -- int11Minor allele frequency- A:0.02EA 120
    rs1114048151,2
    		--79801263(+) GCAGAC/GAGAGG 2 -- int11Minor allele frequency- G:0.33CSA 3

    HapMap Linkage Disequilibrium report for CDHR1 (85954410 - 85979377 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CDHR1: --
    Human Gene Mutation Database (HGMD): CDHR1

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    Disorders / Diseases
    for CDHR1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CDHR1 for disorders           About GeneDecksing

    OMIM gene information: 609502   
    OMIM disorders: 613660  
    UniProtKB/Swiss-Prot: CDHR1_HUMAN, Q96JP9
  • Defects in CDHR1 are the cause of cone-rod dystrophy type 15 (CORD15) [MIM:613660]. CORD15 is an inherited
    • retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the
    macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual
    acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision
    occurs earlier than in retinitis pigmentosa

    10 diseases for CDHR1:    About MalaCards
    cone-rod dystrophy 15    cone-rod dystrophy    leber congenital amaurosis    fundus dystrophy
    macular degeneration    neuronitis    retinal degeneration    retinitis
    alzheimer's disease    pharyngitis

    2 diseases from the University of Copenhagen DISEASES database for CDHR1:
    Fundus dystrophy     Retinal degeneration
    Human Genome Epidemiology (HuGE) Navigator: CDHR1 (0 documents)

    Export disorders for CDHR1 gene to outside databases

    Publications
    for CDHR1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDHR1 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with CDHR1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs. (PubMed id 11597768)1, 2, 3 Nakajima D.... Ohara O. (2001)
    2. Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice. (PubMed id 18654668)1, 2, 9 Yang Z.... Zhang K. (2008)
    3. Protocadherin-21 (PCDH21), a candidate gene for human retinal dystrophies. (PubMed id 16288196)1, 2, 9 Bolz H.... Gal A. (2005)
    4. Mutations in PCDH21 cause autosomal recessive cone-rod dystrophy. (PubMed id 20805371)1, 2 Ostergaard E.... Rosenberg T. (2010)
    5. Biallelic mutation of protocadherin-21 (PCDH21) cause s retinal degeneration in humans. (PubMed id 20087419)1, 9 Henderson R.H....Webster A.R. (2010)
    6. Identification of a novel mutation in the CDHR1 gene i n a family with recessive retinal degeneration. (PubMed id 23044944)1 Duncan J.L....Ayyagari R. (2012)
    7. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (2011)
    8. Mindbomb 1, an E3 ubiquitin ligase, forms a complex w ith RYK to activate Wnt/I^-catenin signaling. (PubMed id 21875946)1 Berndt J.D....Moon R.T. (2011)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)

    External Searches for CDHR1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing CDHR1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 92211 HGNC: 14550 AceView: PCDH21 Ensembl:ENSG00000148600 euGenes: HUgn92211
    ECgene: CDHR1 H-InvDB: CDHR1

    Other Databases showing CDHR1 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1775

    Specialized Databases showing CDHR1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDHR1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CDHR1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CDHR1 gene:
    Search GeneIP for patents involving CDHR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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