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CDH7 Gene

protein-coding   GIFtS: 58
GCID: GC18P063390

Cadherin 7, Type 2

  See CDH7-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cadherin 7, Type 21 2
CDH7L12 3
cadherin-72

External Ids:    HGNC: 17661   Entrez Gene: 10052   Ensembl: ENSG000000811387   OMIM: 6058065   UniProtKB: Q9ULB53   

Export aliases for CDH7 gene to outside databases

Previous GC identifers: GC18P063262 GC18P061566 GC18P061568 GC18P060120


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CDH7 Gene:
This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium
dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane
region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a
HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a
homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly
structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.
(provided by RefSeq, Jul 2008)

GeneCards Summary for CDH7 Gene:
CDH7 (cadherin 7, type 2) is a protein-coding gene. Diseases associated with CDH7 include charge syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH18.

UniProtKB/Swiss-Prot: CADH7_HUMAN, Q9ULB5
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NC_018929.2  NT_010966.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDH7 gene promoter:
         HOXA9   HOXA9B   NF-1   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CDH7 promoter sequence
   Search Chromatin IP Primers for CDH7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDH7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.1   Ensembl cytogenetic band:  18q22.1   HGNC cytogenetic band: 18q22.1

CDH7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDH7 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P063390:  view genomic region     (about GC identifiers)

Start:
63,417,488 bp from pter      End:
63,548,638 bp from pter
Size:
131,151 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CADH7_HUMAN, Q9ULB5 (See protein sequence)
Recommended Name: Cadherin-7 precursor  
Size: 785 amino acids; 87086 Da
Secondary accessions: Q9H157

Explore the universe of human proteins at neXtProt for CDH7: NX_Q9ULB5

Explore proteomics data for CDH7 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn449, Asn530
  • Modification sites at PhosphoSitePlus

  • See CDH7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_004352.2  NP_387450.1  

    ENSEMBL proteins: 
     ENSP00000319166   ENSP00000443030   ENSP00000381058  
    Reactome Protein details: Q9ULB5

    CDH7 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for CDH7

     
    Search eBioscience for Proteins for CDH7 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MCDH: Cadherins / Major cadherins

    5 InterPro protein domains:
     IPR000233 Cadherin_cytoplasmic-dom
     IPR015919 Cadherin-like
     IPR020894 Cadherin_CS
     IPR027397 Catenin_binding_dom
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry Q9ULB5

    ProtoNet protein and cluster: Q9ULB5

    2 Blocks protein domains:
    IPB000233 Cadherin cytoplasmic region
    IPB002126 Cadherin


    UniProtKB/Swiss-Prot: CADH7_HUMAN, Q9ULB5
    Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the
    connections, imparting a strong curvature to the full-length ectodomain (By similarity)
    Similarity: Contains 5 cadherin domains


    Find genes that share domains with CDH7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CADH7_HUMAN, Q9ULB5
    Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
    a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

         Genatlas biochemistry entry for CDH7:
    BH-cadherin chicken cadherin 7-like,transmembrane glycoprotein component of adherens junction,with two
    alternatively spliced isoforms,the major transcript predominantly expressed in the brain,putatively involved in
    synaptic adhesion,axon outgrowth and guidance,heart,the minor expressed in several cancer lines

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    Find genes that share ontologies with CDH7           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDH7
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CDH7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDH7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDH7

    miRNA
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CADH7_HUMAN, Q9ULB5: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum2
    extracellular1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with CDH7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CDH7 About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Cell junction organization
    Cell junction organization0.70
    Cell-Cell communication0.64
    Cell-cell junction organization0.70
    Adherens junctions interactions0.49
    2ERK Signaling
    Rho Family GTPases0.61
    ILK Signaling0.49
    3Nanog in Mammalian ESC Pluripotency
    GSK3 Signaling0.61
    4WNT Signaling
    WNT Signaling
    5S-1P Stimulated Signaling
    S-1P Stimulated Signaling


    Find genes that share SuperPaths with CDH7           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CDH7 (see all 7)
        S-1P Stimulated Signaling
    ILK Signaling
    GSK3 Signaling
    G12-G13 in Cellular Signaling
    Presenilin-Mediated Signaling

    1 BioSystems Pathway for CDH7
        Neural Crest Differentiation

    1 Reactome Pathway for CDH7
        Adherens junctions interactions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CDH7
    Interactions:

        GeneGlobe Interaction Network for CDH7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for CDH7 (Q9ULB53 ENSP000003191664) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDH15P552913, ENSP000002897464I2D: score=1 STRING: ENSP00000289746
    CDH9Q9ULB43, ENSP000002310214I2D: score=1 STRING: ENSP00000231021
    CDH6P552853, ENSP000002650714I2D: score=1 STRING: ENSP00000265071
    CTNNB1P352223, ENSP000003444564I2D: score=2 STRING: ENSP00000344456
    CDH12P552893I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion IEA--
    GO:0016337cell-cell adhesion NAS10861224
    GO:0034329cell junction assembly TAS--
    GO:0034332adherens junction organization TAS--
    GO:0045216cell-cell junction organization TAS--

    Find genes that share ontologies with CDH7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDH7 (CADH7)

    1 HMDB Compound for CDH7    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CDH7 gene (2 alternative transcripts): 
    NM_004361.2  NM_033646.1  

    Unigene Cluster for CDH7:

    Cadherin 7, type 2
    Hs.657522  [show with all ESTs]
    Unigene Representative Sequence: BC036786
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000323011(uc002ljz.3) ENST00000536984(uc002lka.3) ENST00000397968(uc002lkb.3)
    ENST00000581601
    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CDH7
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      QuantiTect SYBR Green Assays in human, mouse, rat CDH7
      QuantiFast Probe-based Assays in human, mouse, rat CDH7

    Additional mRNA sequence: 

    AB035301.1 AJ007611.1 BC036786.1 

    5 DOTS entries:

    DT.40246867  DT.91717100  DT.91753655  DT.97809227  DT.95141633 

    14 AceView cDNA sequences:

    BF668216 AB035301 NM_033646 NM_004361 F08808 BU934923 AJ007611 F11137 
    BM560514 BC036786 BF701677 BF699960 BF700598 BF697112 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDH7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGGCAGGC
    CDH7 Expression
    About this image


    CDH7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
     
     Eye (Sensory Organs)
             Glycinergic Amacrine Cells Inner Nuclear Layer
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    CDH7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDH7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.657522
        Custom PCR Arrays for CDH7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDH7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDH7 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdh71 , 5 cadherin 7, type 21, 5 88.83(n)1
    97.96(a)1
      1 (50.73 cM)5
    2412011  NM_172853.21  NP_766441.11 
     1099824315 
    chicken
    (Gallus gallus)
    Aves CDH71 cadherin 7, type 2 83.44(n)
    93.5(a)
      374007  NM_204187.2  NP_989518.2 
    lizard
    (Anolis carolinensis)
    Reptilia CDH76
    cadherin 7, type 2
    94(a)
    1 ↔ 1
    4(44617447-44778094)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cdh71 cadherin 7, type 2 76.46(n)
    83.65(a)
      100491160  XM_002936071.2  XP_002936117.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cdh71 cadherin 7, type 2 67.7(n)
    74.56(a)
      567704  NM_001077448.1  NP_001070916.1 


    ENSEMBL Gene Tree for CDH7 (if available)
    TreeFam Gene Tree for CDH7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDH7 gene
    CDH182  CDH222  CDH192  CDH102  CDH112  CDH92  CDH62  CDH122  
    CDH82  CDH242  CDH202  CDH52  
    Selected SIMAP similar genes for CDH7 using alignment to 3 protein entries:     CADH7_HUMAN (see all proteins) (see all similar genes):
    CDH9    Nbla04261    CDH8    CDH20    CDH18    CDH6
    CDH22    CDH19    CDH10    CDH12    CDH11    CDH24
    CDH2    FAT3    CDH5    CDH4    CDH13    ME5

    Find genes that share paralogs with CDH7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDH7 (see all 3104)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30618241,2
    C,F--63367333(+) TAAAG-/T/TT/ 
    TTT
    /TTTT
    TTTTT
    4 -- int1 cds1 trp32NA CSA 4
    rs341592441,2
    C--63393686(+) GTCAA-/T/TTT 
            
    TTTTT
    4 -- int1 cds10--------
    rs104601251,2
    C,F,A,H--63415573(+) TCTTAC/TTTGCT 1 -- us2k130Minor allele frequency- T:0.39NS EA NA WA CSA 3134
    rs1404854021,2
    --63415599(+) CTTCCC/TCCTAA 1 -- us2k10--------
    rs1891239471,2
    --63415657(+) ATTCCA/GTATCT 1 -- us2k10--------
    rs1815152111,2
    --63415672(+) CTACAA/GCATAA 1 -- us2k10--------
    rs1444641441,2
    --63415679(+) ATAATA/CCATCT 1 -- us2k10--------
    rs104601261,2
    C,F,A,H--63415698(+) CTCCCT/CTCCTG 1 -- us2k1 trp310Minor allele frequency- C:0.38NS NA WA CSA EA 490
    rs1477961311,2
    --63415731(+) CCTGCC/TGCAGA 1 -- us2k10--------
    rs1401543281,2
    --63415802(+) ATTGTC/TATCAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CDH7 (63417488 - 63548638 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CDH7 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1954972CNV Deletion18987734
    esv3413CNV Deletion18987735
    esv2521787CNV Deletion19546169
    esv1000701CNV Deletion20482838
    esv1389809CNV Deletion17803354
    esv2717231CNV Deletion23290073
    esv1005846CNV Deletion20482838
    esv269715CNV Insertion20981092
    esv268998CNV Insertion20981092
    esv1064517CNV Insertion17803354

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CDH7
    DNA2.0 Custom Variant and Variant Library Synthesis for CDH7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605806    OMIM disorders: --

    1 disease for CDH7:    
    About MalaCards
    charge syndrome


    Find genes that share disorders with CDH7           About GenesLikeMe

    Genetic Association Database (GAD): CDH7
    Human Genome Epidemiology (HuGE) Navigator: CDH7 (3 documents)

    Export disorders for CDH7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDH7 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with CDH7)
        Utopia: connect your pdf to the dynamic
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    1. Characterization of three novel human cadherin genes (CDH7, CDH19, and CDH20) clustered on chromosome 18q22-q23 and with high homology to chicken cadherin-7. (PubMed id 10995570)1, 2, 9 Kools P.... van Roy F. (Genomics 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins. (PubMed id 10861224)1, 2 Shimoyama Y.... Natori M. (Biochem. J. 2000)
    4. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. (PubMed id 9615235)1, 3 Kremmidiotis G....Callen D.F. (Genomics 1998)
    5. Cadherin-7 interacts with melanoma inhibitory activity protein and negatively modulates melanoma cell migration. (PubMed id 19200257)1, 9 Winklmeier A....Bosserhoff A.K. (Cancer Sci. 2009)
    6. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. (PubMed id 24025145)1 Chung S....Nakamura Y. (Breast Cancer Res. 2013)
    7. Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies. (PubMed id 23247143)1 Yu B....Boerwinkle E. (Circ Cardiovasc Genet 2013)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. CHD7 mutations and CHARGE syndrome: the clinical implications of an expanding phenotype. (PubMed id 21378379)1 Bergman J.E....van Ravenswaaij-Arts C.M. (J. Med. Genet. 2011)
    10. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1005 HGNC: 1766 AceView: CDH7 Ensembl:ENSG00000081138 euGenes: HUgn1005
    ECgene: CDH7 H-InvDB: CDH7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDH7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CDH7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDH7 gene:
    Search GeneIP for patents involving CDH7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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