Aliases for CDH7 Gene
External Ids for CDH7 Gene
- HGNC: 1766
- Entrez Gene: 1005
- Ensembl: ENSG00000081138
- OMIM: 605806
- UniProtKB: Q9ULB5
Previous GeneCards Identifiers for CDH7 Gene
- GC18P063262
- GC18P063390
- GC18P061566
- GC18P061568
- GC18P060120
Summaries for CDH7 Gene
-
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016]
GeneCards Summary for CDH7 Gene
CDH7 (Cadherin 7) is a Protein Coding gene. Among its related pathways are Cell junction organization and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH20.
UniProtKB/Swiss-Prot for CDH7 Gene
-
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDH7 Gene
Genomics for CDH7 Gene
Regulatory Elements for CDH7 Gene
Enhancers for CDH7 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH18G065766 | 0.7 | FANTOM5 | 10.5 | +16.7 | 16745 | 0.2 | TBP STAT3 CEBPB RCOR1 EP300 PRDM1 RFX5 | CDH7 GC18M065700 |
| GH18G065768 | 0.8 | ENCODE | 8.5 | +18.4 | 18350 | 1.1 | TBP INSM2 FEZF1 ZNF2 ZEB1 GTF3C2 ZNF366 FOS ZNF362 OVOL3 | CDH7 GC18M065700 |
| GH18G065778 | 0.3 | FANTOM5 | 12.9 | +28.2 | 28159 | 0.3 | CDH7 GC18M065700 | |
| GH18G065829 | 0.3 | FANTOM5 | 10.4 | +79.2 | 79217 | 0.0 | CDH7 GC18M065700 ENSG00000263720 | |
| GH18G065750 | 0.6 | ENCODE | 0.7 | +0.3 | 298 | 0.1 | ZNF263 MAZ MXI1 GLIS2 ZNF362 GLIS1 ZBTB26 BCL11B EGR2 | CDH7 GC18M065700 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CDH7 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CDH7 gene promoter:
Regulatory Element Products
Genomic Location for CDH7 Gene
- Chromosome:
- 18
- Start:
- 65,750,252 bp from pter
- End:
- 65,890,341 bp from pter
- Size:
- 140,090 bases
- Orientation:
- Plus strand
Genomic View for CDH7 Gene
Genes around CDH7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q22.1 by Ensembl
- 18q22.1 by Entrez Gene
- 18q22.1 by HGNC
CDH7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDH7 Gene
Proteins for CDH7 Gene
-
Protein details for CDH7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9ULB5-CADH7_HUMAN
- Recommended name:
- Cadherin-7
- Protein Accession:
- Q9ULB5
- Q9H157
Protein attributes for CDH7 Gene
- Size:
- 785 amino acids
- Molecular mass:
- 87086 Da
- Quaternary structure:
- No Data Available
Protein Expression for CDH7 Gene
Post-translational modifications for CDH7 Gene
Other Protein References for CDH7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CDH7
- Novus Biologicals Antibodies for CDH7
- Invitrogen Antibodies for CDH7
- antibodies-online Antibodies for CDH7: See all 41
- Search GeneTex for Antibodies for CDH7
-
Santa Cruz Biotechnology (SCBT) Antibodies for CDH7
Protein Products
- R&D Systems Proteins and Enzymes for CDH7 (Cadherin-7)
-
OriGene Purified Proteins for CDH7
- Search Origene for MassSpec and Protein Over-expression Lysates for CDH7
- Origene Custom Protein Services for CDH7
- antibodies-online Proteins for CDH7: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CDH7
Assay Products
- antibodies-online Kits for CDH7: See all 11
No data available for DME Specific Peptides for CDH7 Gene
Domains & Families for CDH7 Gene
Gene Families for CDH7 Gene
Protein Domains for CDH7 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CDH7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9ULB5UniProtKB/Swiss-Prot:
CADH7_HUMAN :- Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
- Domain:
-
- Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
Function for CDH7 Gene
Molecular function for CDH7 Gene
- GENATLAS Biochemistry:
- BH-cadherin chicken cadherin 7-like,transmembrane glycoprotein component of adherens junction,with two alternatively spliced isoforms,the major transcript predominantly expressed in the brain,putatively involved in synaptic adhesion,axon outgrowth and guidance,heart,the minor expressed in several cancer lines
- UniProtKB/Swiss-Prot Function:
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for CDH7 Gene
- GenomeRNAi human phenotypes for CDH7:
Animal Model Products
-
Taconic Biosciences Mouse Models for CDH7
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDH7
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CDH7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDH7 gene
- Search ViGene Biosciences for CDH7
CRISPR Products
-
OriGene CRISPR knockouts for CDH7
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDH7
- GenScript: Design CRISPR guide RNA sequences for CDH7
miRNA for CDH7 Gene
- miRTarBase miRNAs that target CDH7
-
- hsa-mir-487b-5p (MIRT444960)
- hsa-mir-487a-5p (MIRT444961)
- hsa-mir-1273e (MIRT444962)
- hsa-mir-6734-5p (MIRT444963)
- hsa-mir-1226-5p (MIRT444964)
- hsa-mir-6834-5p (MIRT444965)
- hsa-mir-526b-5p (MIRT444966)
- hsa-mir-6133 (MIRT444967)
- hsa-mir-6130 (MIRT444968)
- hsa-mir-6129 (MIRT444969)
- hsa-mir-6127 (MIRT444970)
- hsa-mir-4510 (MIRT444971)
- hsa-mir-4419a (MIRT444972)
- hsa-mir-6875-5p (MIRT444973)
- hsa-mir-3126-5p (MIRT444974)
- hsa-mir-5571-5p (MIRT444975)
- hsa-mir-7845-5p (MIRT444976)
- hsa-mir-4677-5p (MIRT497203)
- hsa-mir-6874-5p (MIRT497204)
- hsa-mir-203a-3p (MIRT497205)
- hsa-mir-22-5p (MIRT497206)
- hsa-mir-2116-5p (MIRT497207)
- hsa-mir-124-5p (MIRT497208)
- hsa-mir-6081 (MIRT497209)
- hsa-mir-9-5p (MIRT497210)
- hsa-mir-4635 (MIRT497211)
- hsa-mir-7977 (MIRT671451)
- hsa-mir-6787-5p (MIRT671452)
- hsa-mir-663a (MIRT671453)
- hsa-mir-1908-5p (MIRT671454)
- hsa-mir-566 (MIRT671455)
- hsa-mir-4767 (MIRT671456)
- hsa-mir-6086 (MIRT671457)
- hsa-mir-6720-3p (MIRT671458)
- hsa-mir-377-5p (MIRT671459)
- hsa-mir-6499-5p (MIRT671460)
- hsa-mir-20b-3p (MIRT671461)
- hsa-mir-5690 (MIRT671462)
- hsa-mir-1203 (MIRT671463)
- hsa-mir-2114-5p (MIRT671464)
- hsa-mir-5588-3p (MIRT671465)
- hsa-mir-3178 (MIRT676633)
- hsa-mir-6781-5p (MIRT676634)
- hsa-mir-24-3p (MIRT676635)
- hsa-mir-4284 (MIRT676636)
- hsa-mir-3918 (MIRT676637)
- hsa-mir-383-3p (MIRT676638)
- hsa-mir-6768-5p (MIRT676639)
- hsa-mir-8485 (MIRT676640)
- hsa-mir-6513-5p (MIRT688758)
- hsa-mir-887-5p (MIRT688759)
- hsa-mir-3913-5p (MIRT688760)
- hsa-mir-3122 (MIRT688761)
- hsa-mir-450a-1-3p (MIRT688762)
- hsa-mir-6780a-5p (MIRT688763)
- hsa-mir-6779-5p (MIRT688764)
- hsa-mir-3689c (MIRT688765)
- hsa-mir-3689b-3p (MIRT688766)
- hsa-mir-3689a-3p (MIRT688767)
- hsa-mir-30b-3p (MIRT688768)
- hsa-mir-1273h-5p (MIRT688769)
- hsa-mir-6788-5p (MIRT688770)
- hsa-mir-30c-2-3p (MIRT688771)
- hsa-mir-30c-1-3p (MIRT688772)
- hsa-mir-6799-5p (MIRT688773)
- hsa-mir-6883-5p (MIRT688774)
- hsa-mir-6785-5p (MIRT688775)
- hsa-mir-4728-5p (MIRT688776)
- hsa-mir-149-3p (MIRT688777)
- hsa-mir-7106-5p (MIRT688778)
- hsa-mir-6087 (MIRT688779)
- hsa-mir-6089 (MIRT688780)
- hsa-mir-6739-3p (MIRT725583)
- hsa-mir-578 (MIRT725584)
- hsa-mir-7156-5p (MIRT725585)
- hsa-mir-4273 (MIRT725586)
- hsa-mir-4795-3p (MIRT725587)
- hsa-mir-4752 (MIRT725588)
- hsa-mir-513b-5p (MIRT725589)
- hsa-mir-8056 (MIRT725590)
- hsa-mir-3691-5p (MIRT725591)
- hsa-mir-376c-5p (MIRT725592)
- hsa-mir-376b-5p (MIRT725593)
- hsa-mir-6862-5p (MIRT725594)
- hsa-mir-4253 (MIRT725595)
- hsa-mir-4719 (MIRT725596)
- hsa-mir-4657 (MIRT725597)
- hsa-mir-4491 (MIRT725598)
miRNA Products
- Search ViGene Biosciences for CDH7
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CDH7
- Browse OriGene Inhibitory RNA Products For CDH7
-
ViGene Biosciences ready-to-package AAV shRNAs for CDH7 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CDH7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDH7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CDH7
-
ViGene Biosciences adenoviral particle packaged cDNA for CDH7 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CDH7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDH7 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDH7 Gene
Localization for CDH7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CDH7 Gene
- Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endoplasmic reticulum | 2 |
| extracellular | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CDH7 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell junction organization | ||
| 2 | ERK Signaling |
.49
|
|
| 3 | G12-G13 in Cellular Signaling | ||
| 4 | Nanog in Mammalian ESC Pluripotency |
.61
|
|
| 5 | Presenilin-Mediated Signaling | ||
Pathways by source for CDH7 Gene
1 BioSystems pathway for CDH7 Gene
4 Reactome pathways for CDH7 Gene
7 Qiagen pathways for CDH7 Gene
Interacting Proteins for CDH7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules | IEA | -- |
| GO:0016337 | single organismal cell-cell adhesion | NAS | 10861224 |
| GO:0034332 | adherens junction organization | TAS | -- |
No data available for SIGNOR curated interactions for CDH7 Gene
Drugs & Compounds for CDH7 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| calcium | Nutra | 0 |
Transcripts for CDH7 Gene
mRNA/cDNA for CDH7 Gene
- (4) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (14) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CDH7
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDH7
- GenScript: Design CRISPR guide RNA sequences for CDH7
miRNA Products
- Search ViGene Biosciences for CDH7
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CDH7
- Browse OriGene Inhibitory RNA Products For CDH7
-
ViGene Biosciences ready-to-package AAV shRNAs for CDH7 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CDH7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDH7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CDH7 Gene
mRNA differential expression in normal tissues according to GTEx for CDH7 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x12.2), Brain - Cerebellum (x8.9), and Nerve - Tibial (x6.9).
This gene is overexpressed in Plasma (55.2) and Heart (11.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CDH7 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CDH7 Gene:
CDH7SOURCE GeneReport for Unigene cluster for CDH7 Gene:
Hs.657522Evidence on tissue expression from TISSUES for CDH7 Gene
- Nervous system(2.5)
Primer Products
-
OriGene qPCR primer pairs for CDH7
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDH7 Gene
Orthologs for CDH7 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CDH7 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CDH7 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CDH7 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CDH7 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Cdh7 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cdh7 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CDH7 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CDH7 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CDH7 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cdh7 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cdh7 34 35 |
|
||
| CDH7 (1 of 2) 35 |
|
OneToMany |
- Species where no ortholog for CDH7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CDH7 Gene
Paralogs for CDH7 Gene
(25) SIMAP similar genes for CDH7 Gene using alignment to 3 proteins:
Variants for CDH7 Gene
| SNP ID | Clin | Chr 18 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000039196 | -- | 65,761,628(+) | ATTCA(G/T)AAACC | intron-variant | |
| rs1000041233 | -- | 65,864,617(+) | GGAGC(A/G)GTGGC | intron-variant, downstream-variant-500B | |
| rs1000058661 | -- | 65,864,840(+) | GAGCC(A/G)AGATC | intron-variant | |
| rs1000062656 | -- | 65,792,761(+) | ATTCT(A/G)TTAGG | intron-variant | |
| rs1000072487 | -- | 65,809,603(+) | AATAA(A/C)ATTTC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1625n106 | CNV | deletion | 24896259 |
| esv1000701 | CNV | deletion | 20482838 |
| esv1005846 | CNV | deletion | 20482838 |
| esv1064517 | CNV | insertion | 17803354 |
| esv1389809 | CNV | deletion | 17803354 |
| esv1954972 | CNV | deletion | 18987734 |
| esv2521787 | CNV | deletion | 19546169 |
| esv2717231 | CNV | deletion | 23290073 |
| esv3119346 | CNV | deletion | 24192839 |
| esv3304720 | CNV | mobile element insertion | 20981092 |
| esv3364230 | CNV | insertion | 20981092 |
| esv3413 | CNV | loss | 18987735 |
| esv3555529 | CNV | deletion | 23714750 |
| esv3583120 | CNV | loss | 25503493 |
| esv3584946 | CNV | gain | 24956385 |
| esv3642844 | CNV | loss | 21293372 |
| esv3893118 | CNV | gain | 25118596 |
| esv6192 | CNV | loss | 19470904 |
| nsv1067311 | CNV | loss | 25217958 |
| nsv1071856 | CNV | deletion | 25765185 |
| nsv1123188 | CNV | deletion | 24896259 |
| nsv458102 | CNV | loss | 19166990 |
| nsv510462 | OTHER | sequence alteration | 20534489 |
| nsv577157 | CNV | loss | 21841781 |
| nsv828267 | CNV | gain | 20364138 |
| nsv833675 | CNV | gain | 17160897 |
| nsv833676 | CNV | gain | 17160897 |
| nsv954124 | CNV | deletion | 24416366 |
| nsv954961 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
3.43% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.33;
26.35% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CDH7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CDH7
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDH7 Gene
Disorders for CDH7 Gene
Relevant External Links for CDH7
No disorders were found for CDH7 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDH7 Gene
Publications for CDH7 Gene
- Characterization of three novel human cadherin genes (CDH7, CDH19, and CDH20) clustered on chromosome 18q22-q23 and with high homology to chicken cadherin-7. (PMID: 10995570) Kools P. … van Roy F. (Genomics 2000) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Cadherin-7 interacts with melanoma inhibitory activity protein and negatively modulates melanoma cell migration. (PMID: 19200257) Winklmeier A. … Bosserhoff A.K. (Cancer Sci. 2009) 3 22 64
- Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins. (PMID: 10861224) Shimoyama Y. … Natori M. (Biochem. J. 2000) 3 4 64
- Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. (PMID: 9615235) Kremmidiotis G. … Callen D.F. (Genomics 1998) 2 3 64
Products for CDH7 Gene
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- Custom Antibody ServicesOriGene Antibodies for CDH7
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- OriGene qPCR primer pairs for CDH7
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- Novus Biologicals Antibodies for CDH7
- Novus Biologicals proteins and lysates for CDH7
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for CDH7
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for CDH7: See all 41
- antibodies-online Kits for CDH7: See all 11
- antibodies-online Proteins for CDH7: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CDH7
- Search GeneTex for Proteins for CDH7
- ViGene Biosciences adenoviral particle packaged cDNA for CDH7 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CDH7 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CDH7 gene
- Search ViGene Biosciences for CDH7
- Santa Cruz Biotechnology (SCBT) Antibodies for CDH7
- Search Santa Cruz Biotechnology (SCBT) for CDH7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CDH7
- Horizon Cell Lines for CDH7
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDH7
- VectorBuilder custom plasmid, inducible vectors for CDH7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDH7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CDH7 Gene
- (1) GeneCards
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- (8) Gene Wiki
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- (28) RNAdb
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- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
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- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
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- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
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- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
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- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
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- (146) Cyagen
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- (148) SNPedia
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- (155) Gene ORGANizer