Aliases for CDH6 Gene
External Ids for CDH6 Gene
Previous GeneCards Identifiers for CDH6 Gene
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
GeneCards Summary for CDH6 Gene
CDH6 (Cadherin 6, Type 2, K-Cadherin (Fetal Kidney)) is a Protein Coding gene. Diseases associated with CDH6 include renal cell carcinoma. Among its related pathways are ERK Signaling and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH19.
UniProtKB/Swiss-Prot for CDH6 Gene
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types