External Ids for CDH19 Gene
Previous GeneCards Identifiers for CDH19 Gene
This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for CDH19 Gene
CDH19 (Cadherin 19) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and G12-G13 in Cellular Signaling. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH7.
UniProtKB/Swiss-Prot for CDH19 Gene
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.