External Ids for CDH19 Gene
Previous GeneCards Identifiers for CDH19 Gene
This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for CDH19 Gene
CDH19 (Cadherin 19) is a Protein Coding gene. Among its related pathways are Nanog in Mammalian ESC Pluripotency and ERK Signaling. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH7.
UniProtKB/Swiss-Prot for CDH19 Gene
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.