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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDH17 Gene

protein-coding   GIFtS: 59
GCID: GC08M095208

Cadherin 17, LI Cadherin (Liver-Intestine)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cadherin 17, LI Cadherin (Liver-Intestine)1 2     cadherin-162
Intestinal Peptide-Associated Transporter HPT-12 3     cadherin-172
Liver-Intestine Cadherin2 3     HPT-1 Cadherin2
LI-cadherin2 3     Human Intestinal Peptide-Associated Transporter HPT-12
CDH162 5     Human Peptide Transporter 12
HPT12 5     LI Cadherin2
HPT-12     

External Ids:    HGNC: 17561   Entrez Gene: 10152   Ensembl: ENSG000000791127   OMIM: 6030175   UniProtKB: Q128643   

Export aliases for CDH17 gene to outside databases

Previous GC identifers: GC08M093885 GC08M094985 GC08M094808 GC08M095095 GC08M090347


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CDH17 Gene:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated
glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin
domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of
the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in
the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a
role in the morphological organization of liver and intestine. Alternative splicing results in multiple
transcript variants. (provided by RefSeq, Jan 2009)

GeneCards Summary for CDH17 Gene: 
CDH17 (cadherin 17, LI cadherin (liver-intestine)) is a protein-coding gene. Diseases associated with CDH17 include noma, and pancreatitis, and among its related super-pathways are MAPK Signaling and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include proton-dependent oligopeptide secondary active transmembrane transporter activity and calcium ion binding. An important paralog of this gene is DSC1.

UniProtKB/Swiss-Prot: CAD17_HUMAN, Q12864
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell
types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in
intestinal peptide transport

Gene Wiki entry for CDH17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDH17 gene promoter:
         Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDH17 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDH17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDH17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.1   Ensembl cytogenetic band:  8q22.1   HGNC cytogenetic band: 8q22.1

CDH17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDH17 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M095208:  view genomic region     (about GC identifiers)

Start:
95,139,394 bp from pter      End:
95,229,531 bp from pter
Size:
90,138 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CAD17_HUMAN, Q12864 (See protein sequence)
Recommended Name: Cadherin-17 precursor  
Size: 832 amino acids; 92219 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: Q15336 Q2M2E0

Explore the universe of human proteins at neXtProt for CDH17: NX_Q12864

Explore proteomics data for CDH17 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q12864

  • CDH17 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CDH17 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001138135.1  NP_004054.3  

    ENSEMBL proteins: 
     ENSP00000027335   ENSP00000392811   ENSP00000401468   ENSP00000429730   ENSP00000428189  

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    Sino Biological Cell Lysate for CDH17 
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    Cloud-Clone Corp. Proteins for CDH17 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane ----
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0016323basolateral plasma membrane IEA--

    CDH17 for ontologies           About GeneDecksing



    CDH17 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MCDH: Cadherins / Major cadherins

    3 InterPro protein domains:
     IPR015919 Cadherin-like
     IPR020894 Cadherin_CS
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry Q12864

    ProtoNet protein and cluster: Q12864

    1 Blocks protein domain: IPB002126 Cadherin

    UniProtKB/Swiss-Prot: CAD17_HUMAN, Q12864
    Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the
    connections, imparting a strong curvature to the full-length ectodomain (By similarity)
    Similarity: Contains 7 cadherin domains


    CDH17 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAD17_HUMAN, Q12864
    Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
    a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell
    types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in
    intestinal peptide transport

         Genatlas biochemistry entry for CDH17:
    cadherin 17,LI-cadherin,transmembrane glycoprotein component of adherens junction,expressed in the liver and
    intestine located in a region deleted (LOH) in adult acute leukemia

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity TAS8153632
    GO:0005427proton-dependent oligopeptide secondary active transmembrane transporter activity IEA--
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----
         
    CDH17 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cdh17):
     cellular  hematopoietic system  immune system 

    CDH17 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cdh17tm1Ohn for CDH17

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CDH17 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CDH17

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    SwitchGear 3'UTR luciferase reporter plasmidCDH17 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDH17


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CDH17 About   (see all 7)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Rho Family GTPases
    Rho Family GTPases0.61
    ILK Signaling0.49
    2Nanog in Mammalian ESC Pluripotency
    GSK3 Signaling0.61
    3Canonical Wnt Pathway
    Canonical Wnt Pathway0.53
    4WNT Signaling
    WNT Signaling
    5S-1P Stimulated Signaling
    S-1P Stimulated Signaling

    5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDH17 (see all 7)
        S-1P Stimulated Signaling
    ILK Signaling
    GSK3 Signaling
    G12-G13 in Cellular Signaling
    Presenilin-Mediated Signaling

    1 Sino Biological Pathway for CDH17 
        Canonical Wnt Pathway


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDH17

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for CDH17 (Q128643 ENSP000000273354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352223, ENSP000003444564I2D: score=1 STRING: ENSP00000344456
    ANXA4P095253I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport NAS8153632
    GO:0006857oligopeptide transport ----
    GO:0007155cell adhesion TAS8153632
    GO:0007156homophilic cell adhesion IEA--
    GO:0016339calcium-dependent cell-cell adhesion IEA--

    CDH17 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CDH17 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDH17 (CAD17)

    1 HMDB Compound for CDH17    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 Novoseek inferred chemical compound relationship for CDH17 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    valacyclovir 60 1 12821497 (1)

    Search CenterWatch for drugs/clinical trials and news about CDH17 / CAD17

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CDH17 gene (2 alternative transcripts): 
    NM_001144663.1  NM_004063.3  

    Unigene Cluster for CDH17:

    Cadherin 17, LI cadherin (liver-intestine)
    Hs.591853  [show with all ESTs]
    Unigene Representative Sequence: NM_001144663
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000027335(uc003ygh.2 uc011lgo.1 uc011lgp.1) ENST00000441892
    ENST00000450165 ENST00000520952 ENST00000521491
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    Additional mRNA sequence: 

    AK130441.1 AK300638.1 AK301001.1 AK312873.1 BC112013.1 BC113464.1 U07969.1 X83228.1 

    3 DOTS entries:

    DT.111667  DT.86855489  DT.95146647 

    24/86 AceView cDNA sequences (see all 86):

    CB129071 AI732453 AI922856 NM_004063 AU076801 X83228 BX951110 CB129480 
    BX282194 AA376878 CB130703 BV204411 BP383197 AA313526 AA053188 BP383309 
    CB163054 AI601183 BV204415 BP383072 BX478973 AI721059 AW859603 BV204412 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDH17 expression in normal human tissues (normalized intensities)      CDH17 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAGAGTGG
    CDH17 Expression
    About this image


    CDH17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Intestine (Gastrointestinal Tract)    fully expand to see all 5 entries
             small intestine ; glandular cells   
             small intestine   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             rectum ; glandular cells   
             colonic mucosal (ibs)   
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Renal Collecting Duct System
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 2 entries
             stomach, upper ; glandular cells   
     
     Neural Tube (Nervous System)
             Rhombencephalon

    See CDH17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDH17

    SOURCE GeneReport for Unigene cluster: Hs.591853

    UniProtKB/Swiss-Prot: CAD17_HUMAN, Q12864
    Tissue specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung,
    liver, brain, adrenal gland and skin

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDH17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CDH17 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdh171 , 5 cadherin 171, 5 81.14(n)1
    79.44(a)1
      4 (5.35 cM)5
    125571  NM_019753.41  NP_062727.11 
     117581475 
    chicken
    (Gallus gallus)
    Aves CDH171 cadherin 17, LI cadherin (liver-intestine) 58.79(n)
    50.13(a)
      420225  NM_001199495.1  NP_001186424.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDH176
    cadherin 17, LI cadherin (liver-intestine)
    48(a)
    1 ↔ 1
    4(18877410-18922494)
    zebrafish
    (Danio rerio)
    Actinopterygii AF428098.12   -- 76.19(n)   378452  AF428098.1 


    ENSEMBL Gene Tree for CDH17 (if available)
    TreeFam Gene Tree for CDH17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDH17 gene
    DSC12  CDH42  DSG42  CDH162  DSG12  CDH132  CDH32  DSG22  
    CDH12  CDH262  DSC32  CDH22  DSC22  CDH152  DSG32  
    9 SIMAP similar genes for CDH17 using alignment to 4 protein entries:     CAD17_HUMAN (see all proteins):
    CDH11    CDH8    CDH19    CDH16    CDH5    FAT3
    CDH1    CDH22    DSC2

    CDH17 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1995 SNPs in CDH17 are shown (see all 1995)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1174879211,2
    Cuntested195140479(+) TCTCAA/C/GAGGTT 4 L V mis11NA 120
    rs575730541,2
    C,F--90404851(+) GATCA-/AAGACCT 2 -- int13Minor allele frequency- AA:0.33NA CSA 6
    rs1504241831,2
    --95138945(+) CAGACC/GCTGTT 2 -- ds50010--------
    rs1836187401,2
    --95139183(+) CTGTTG/TTCTTC 2 -- ds50010--------
    rs763763861,2
    C,F--95139263(+) CTGTCT/CAGGGA 2 -- ds50013Minor allele frequency- C:0.16WA CSA 122
    rs736944001,2
    C,F--95139352(+) TTCTGT/CCCTTC 2 -- ds50012Minor allele frequency- C:0.05WA 120
    rs1453711631,2
    --95139431(+) TTGATC/TTGTCA 2 -- ut310--------
    rs78130341,2
    C,F,A,H--95139664(+) AGCAAC/GATGTC 2 -- ut31 ese37Minor allele frequency- G:0.00NS EA NA 560
    rs1881759891,2
    --95139665(+) GCAACA/GTGTCA 2 -- ut310--------
    rs736944021,2
    C--95139673(+) TCACAT/CTGATT 2 -- ut313Minor allele frequency- C:0.14WA CSA 122

    HapMap Linkage Disequilibrium report for CDH17 (95139394 - 95229531 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CDH17:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2660000CNV Deletion23128226
    nsv6311CNV Insertion18451855
    nsv396169CNV Loss16902084
    nsv831401CNV Loss17160897
    dgv465n21CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603017    OMIM disorders: --

    16 diseases for CDH17:    About MalaCards
    noma    pancreatitis    gastric cancer    hepatitis b
    hepatocellular carcinoma    acute leukemia    adenocarcinoma    liver disease
    cholangiocarcinoma    pneumonia    hepatitis    colon cancer
    colorectal cancer    esophagitis    ovarian cancer    leukemia


    CDH17 for disorders           About GeneDecksing

    10/11 Novoseek inferred disease relationships for CDH17 gene (see all 11)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma gastric 55.6 2 16044349 (1), 15732140 (1)
    gastric carcinoma 55.1 24 18353622 (9), 16044349 (3), 16634965 (1), 11413113 (1) (see all 6)
    gastric cancer 54 17 17063305 (4), 17999183 (3), 16044349 (1), 16253763 (1) (see all 6)
    metaplasia 53.4 6 11413113 (4), 16044349 (1), 15732140 (1)
    hepatocellular carcinoma 46.2 15 19626651 (3), 15701831 (2), 19460698 (2), 19676131 (1) (see all 9)
    metastasis 39.1 16 17063305 (6), 15178443 (3), 15279905 (1), 18353622 (1) (see all 6)
    tumors 30.2 26 15701831 (3), 19626651 (3), 19956853 (2), 17063305 (2) (see all 11)
    adenocarcinoma 29.6 11 18552820 (3), 12824888 (3), 11413113 (1), 15732140 (1)
    carcinoma 19.4 13 18552820 (2), 16044349 (1), 17589897 (1), 12824888 (1) (see all 5)
    cancer 3.96 1 18552820 (1)

    Genetic Association Database (GAD): CDH17
    Human Genome Epidemiology (HuGE) Navigator: CDH17 (1 document)

    Export disorders for CDH17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDH17 gene, integrated from 9 sources (see all 71):
    (articles sorted by number of sources associating them with CDH17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genomewide association study points to multiple loc i that predict antidepressant drug treatment outcome in depression. (PubMed id 19736353)1, 4 Ising M....MA1ller-Myhsok B. (2009)
    2. Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma. (PubMed id 10191097)1, 3 Chalmers I.J....Atkinson M.J. (1999)
    3. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. (PubMed id 9615235)1, 3 Kremmidiotis G....Callen D.F. (1998)
    4. Association of intestinal peptide transport with a protein related to the cadherin superfamily. (PubMed id 8153632)1, 2 Dantzig A.H.... Skatrud P.L. (1994)
    5. A clinicopathological study on the expression of cadherin-17 and caudal-related homeobox transcription factor (CDX2) in human gastric carcinoma. (PubMed id 18353622)1, 9 Ge J....Chen Z. (2008)
    6. Loss of liver-intestine cadherin in human intrahepati c cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive tr anscription factor-1 and placental growth factor. (PubMed id 19956853)1, 9 Takamura M....Aoyagi Y. (2010)
    7. Cadherin-17 is a useful diagnostic marker for adenocarcinomas of the digestive system. (PubMed id 18552820)1, 9 Su M.C....Jeng Y.M. (2008)
    8. Reduced expression of liver-intestine cadherin is associated with progression and lymph node metastasis of human colorectal carcinoma. (PubMed id 15279905)1, 9 Takamura M....Aoyagi Y. (2004)
    9. Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas. (PubMed id 12824888)1, 9 Takamura M....Hirohashi S. (2003)
    10. Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma. (PubMed id 15701831)1, 9 Wang X.Q....Fan S.T. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1015 HGNC: 1756 AceView: CDH17 Ensembl:ENSG00000079112 euGenes: HUgn1015
    ECgene: CDH17 H-InvDB: CDH17

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDH17 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CDH17 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CDH17 gene:
    Search GeneIP for patents involving CDH17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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