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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDH16 Gene

protein-coding   GIFtS: 55
GCID: GC16M066942

cadherin 16, KSP-cadherin
 Explore 13 diseases affiliated with
CDH16 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CDH16    

Aliases
for CDH16 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cadherin 16, KSP-Cadherin1 2
Kidney-Specific Cadherin2 3
KSP-Cadherin1
Cadherin-161
Ksp-Cadherin1

External Ids:    HGNC: 17551   Entrez Gene: 10142   Ensembl: ENSG000001665897   OMIM: 6031185   UniProtKB: O753093   

Export aliases for CDH16 gene to outside databases

Previous GC identifers: GC16M057636 GC16M067319 GC16M066677 GC16M066718 GC16M065499 GC16M052816


Summaries
for CDH16 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CDH16:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.
Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily
members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin
domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV
adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the
protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic
direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been
identified. (provided by RefSeq, Mar 2011)

UniProtKB/Swiss-Prot: CAD16_HUMAN, O75309
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a
homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

Gene Wiki entry for CDH16


Genomic Views
for CDH16 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDH16 gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CDH16 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDH16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDH16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

CDH16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDH16 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M066942:  view genomic region     (about GC identifiers)

Start:
 66,942,025 bp from pter      End:
 66,952,887 bp from pter
Size:
 10,863 bases      Orientation:
 minus strand

Proteins
for CDH16 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CAD16_HUMAN, O75309 (See protein sequence)
Recommended Name: Cadherin-16 precursor  
Size: 829 amino acids; 89923 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (Probable)
Secondary accessions: H3BPD3 Q6UW93
Alternative splicing: 3 isoforms:  O75309-1   O75309-2   O75309-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDH16: NX_O75309

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75309

    • CDH16 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001191673.1  NP_001191674.1  NP_001191675.1  NP_004053.1  

    ENSEMBL proteins: 
     ENSP00000377619   ENSP00000299752   ENSP00000455263   ENSP00000456690   ENSP00000454784  
     ENSP00000455523   ENSP00000456891   ENSP00000460891   ENSP00000463451  

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    Novus Biologicals CDH16 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CDH16

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--


    CDH16 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CDH16

    Protein Domains /
    Families
    for CDH16 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CDH16 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015919 Cadherin-like
     IPR020894 Cadherin_CS
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry O75309

    ProtoNet protein and cluster: O75309

    1 Blocks protein family: IPB002126 Cadherin

    UniProtKB/Swiss-Prot: CAD16_HUMAN, O75309
    Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections,
    imparting a strong curvature to the full-length ectodomain (By similarity)
    Similarity: Contains 6 cadherin domains


    Function
    for CDH16 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CAD16_HUMAN, O75309
    Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a
    homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

         Genatlas biochemistry entry for CDH16:
    cadherin 16,Ksp-cadherin,130kDa,transmembrane glycoprotein component of adherens junction,kidney specific,wsith three
    alternatively spliced isoforms

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for CDH16

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--


    CDH16 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for CDH16:
     Increased cell death HMECs cel  Increased cell death in breast 


    Pathways & Interactions
    for CDH16 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Rho Family GTPases
    		Rho Family GTPases1.00
    		ILK Signaling0.45
    2WNT Signaling
    		WNT Signaling1.00
    3S-1P Stimulated Signaling
    		S-1P Stimulated Signaling1.00
    4Presenilin-Mediated Signaling
    		Presenilin-Mediated Signaling1.00
    5G12-G13 in Cellular Signaling
    		G12-G13 in Cellular Signaling1.00

    5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDH16 (see all 7)
        S-1P Stimulated Signaling
    ILK Signaling
    GSK3 Signaling
    G12-G13 in Cellular Signaling
    Presenilin-Mediated Signaling


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDH16

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CDH16 (O753093 ENSP000002997524) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352223, ENSP000003444564I2D: score=2 STRING: ENSP00000344456
    G6PCENSP000002538014STRING: ENSP00000253801
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion TAS9721215
    GO:0007156homophilic cell adhesion IEA--


    CDH16 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CDH16 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDH16

    1 HMDB Compound for CDH16    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about CDH16 / CAD16 

    Transcripts
    for CDH16 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CDH16 gene (4 alternative transcripts): 
    NM_001204744.1  NM_001204745.1  NM_001204746.1  NM_004062.3  

    Unigene Cluster for CDH16:

    Cadherin 16, KSP-cadherin
    Hs.513660  [show with all ESTs]
    Unigene Representative Sequence: NM_004062
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394055 ENST00000299752(uc010cdy.3 uc002eql.3 uc021tjx.1 uc002eqm.3)
    ENST00000568632 ENST00000570262 ENST00000565796 ENST00000567269 ENST00000568698
    ENST00000567009 ENST00000565235

    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDH16

    Additional cDNA sequence: 

    AF016272.1 AK225544.1 AK298255.1 AK298334.1 AK313101.1 AY358911.1 BC027912.2 

    7 DOTS entries:

    DT.453756  DT.91638378  DT.120681798  DT.100018712  DT.102823716  DT.120681799  DT.120681794 

    24/36 AceView cDNA sequences (see all 36):

    BG430251 BI760840 BC027912 CD617915 CD617923 AY358911 AL696168 BI766687 
    NM_004062 AK075243 AF016272 AI791569 AA340453 BG054513 BI759247 AA401704 
    AI792783 AI733487 BX099630 CD617916 BI765808 CD617918 BI759833 CD617910 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CDH16 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^
    SP1:                                                        -                                                                             -                     
    SP2:                                                                          -                                                                                 
    SP3:                                                        -                                                                                                   
    SP4:                                                  -     -     -     -     -     -                                                                           
    SP5:                          -                             -                                                                                                   

    ExUns: 18a · 18b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for CDH16

    Expression
    for CDH16 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDH16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGAGTGCTCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CDH16 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyUreteric BudUreteric Bud CellsKidney
    HeartAtrioventricular CanalAtrioventricular Canal CellsMyocardium
    KidneyUreteric BudUreteric Bud Tip CellsKidney
    TestisSeminiferous TubulesSertoli cellsTestis
    KidneyUreteric BudKidney
    Lower Urinary TractUreterLower Urinary Tract
    Reproductive SystemVas DeferensReproductive System
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    mK4 (Cell line)Kidney
    mK3 (Cell line)Kidney

    See CDH16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDH16

    SOURCE GeneReport for Unigene cluster: Hs.513660

    UniProtKB/Swiss-Prot: CAD16_HUMAN, O75309
    Tissue specificity: Kidney specific

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    In Situ
    Assay Products:     
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    Orthologs
    for CDH16 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CDH16 gene from 1/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    zebrafish
    (Danio rerio)    		 Actinopterygii BX511136.16
    		 --
    		 34(a)
    		 1 ↔ 1
    		 7(45848461-45945450)


    ENSEMBL Gene Tree for CDH16 (if available)
    TreeFam Gene Tree for CDH16 (if available) 

    Paralogs
    for CDH16 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDH16 gene
    CDH172  
    2 SIMAP similar genes for CDH16 using alignment to 6 protein entries:     CAD16_HUMAN (see all proteins):
    CDH17    DSC2

    CDH16 for paralogs           About GeneDecksing



    Genomic Variants
    for CDH16 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/281 NCBI SNPs in CDH16 are shown (see all 281)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1454104991,2
    		--66941543(+) CTCACC/TTCACA 4 -- ds50010--------
    rs1140651521,2
    		C,F,--66941589(+) GGGCCC/TTGCAG 4 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1476691541,2
    		--66941635(+) TGACTC/TATGCA 4 -- ds50010--------
    rs794774341,2
    		F,--66941794(+) CCAGGG/ATCTGT 4 -- ds50011Minor allele frequency- A:0.03EA 120
    rs1919539551,2
    		--66941937(+) TTTCTA/CTGTGG 4 -- ds50010--------
    rs1423163711,2
    		--66941943(+) TGTGGA/CAGGAG 4 -- ds50010--------
    rs1847891661,2
    		--66941966(+) TGAAAA/GAGCAG 4 -- ds50010--------
    rs774631711,2
    		C,F,--66942206(+) CCTGTC/TCCCTG 4 -- ut312Minor allele frequency- T:0.09WA EA 238
    rs1501918441,2
    		C,--66942264(+) AGAGGC/TCAAGC 4 -- ut310--------
    rs1386851911,2
    		C,--66942330(+) TGCTGG/ATTGAT 8 /P /S mis11Minor allele frequency- A:0.00NA 4552

    HapMap Linkage Disequilibrium report for CDH16 (66942025 - 66952887 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CDH16: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for CDH16 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CDH16 for disorders           About GeneDecksing

    OMIM gene information: 603118    OMIM disorders: --

    13 diseases for CDH16:    About MalaCards
    renal clear cell carcinoma    chromophobe renal cell carcinoma    oxyphilic adenoma    renal cell carcinoma
    papillary renal cell carcinoma    spindle cell carcinoma    nephrogenic adenoma    renal oncocytoma
    wilms tumor    adenoma    carcinoma    breast carcinoma
    leukemia

    3 diseases from the University of Copenhagen DISEASES database for CDH16:
    Renal oncocytoma     Renal cell carcinoma     Oxyphilic adenoma

    6 Novoseek disease relationships for CDH16 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    kidney tumor 81.7 3 15696118 (2), 17374232 (1)
    oncocytoma 79.2 11 15712178 (4), 15696118 (2), 16753598 (2), 17374232 (1)
    renal clear cell carcinoma 74.1 4 15712178 (2), 17374232 (1)
    carcinoma renal cell 68.3 19 15712178 (5), 19228645 (2), 15886705 (2), 16753598 (2) (see all 6)
    tumors 27 7 15712178 (2), 17240302 (1), 17374232 (1), 19228645 (1)
    carcinoma 23 4 15712178 (2)


    Export disorders for CDH16 gene to outside databases

    Publications
    for CDH16 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDH16 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with CDH16)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin. (PubMed id 9721215)1, 2, 3, 9 Thomson R.B....Aronson P.S. (1998)
    2. Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. (PubMed id 7615566)1, 3, 9 Thomson R.B....Aronson P.S. (1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. Expression of Ksp-cadherin during kidney development and in renal cell carcinoma. (PubMed id 15886705)1, 9 Thedieck C....Klein G. (2005)
    6. alpha B-crystallin is a cytoplasmic interaction partner of the kidney-specific cadherin-16. (PubMed id 18343407)1, 9 Thedieck C....Klein G. (2008)
    7. Assignment of E-cadherin (CDH1) and KSP-cadherin (CDH16) to chromosome 16q22.1 by radiation hybrid mapping. (PubMed id 10828602)1, 9 Baudry D. and Jeanpierre C. (2000)
    8. Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications. (PubMed id 17895753)1, 9 Kuehn A....Amin M.B. (2007)
    9. CDH16/Ksp-cadherin is expressed in the developing thyr oid gland and is strongly down-regulated in thyroid carcinomas. (PubMed id 22028439)1 Cali G....Nitsch L. (2012)
    10. Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. (PubMed id 15670782)1 Hishikawa K....Fujita T. (2005)

    External Searches for CDH16 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing CDH16 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1014 HGNC: 1755 AceView: CDH16 Ensembl:ENSG00000166589 euGenes: HUgn1014
    ECgene: CDH16 H-InvDB: CDH16

    Other Databases showing CDH16 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CDH16 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDH16 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CDH16 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CDH16 gene:
    Search GeneIP for patents involving CDH16

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