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CDH10 Gene

protein-coding   GIFtS: 60
GCID: GC05M024522

Cadherin 10, Type 2 (T2-Cadherin)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cadherin 10, Type 2 (T2-Cadherin)1 2
T2-cadherin2 3
cadherin-102

External Ids:    HGNC: 17491   Entrez Gene: 10082   Ensembl: ENSG000000407317   OMIM: 6045555   UniProtKB: Q9Y6N83   

Export aliases for CDH10 gene to outside databases

Previous GC identifers: GC05M024168 GC05M024923 GC05M024486 GC05M024532


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CDH10 Gene:
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that
mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal
extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic
domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to
determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are
defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This
particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon
outgrowth and guidance. (provided by RefSeq, Jan 2011)

GeneCards Summary for CDH10 Gene:
CDH10 (cadherin 10, type 2 (T2-cadherin)) is a protein-coding gene. Diseases associated with CDH10 include autism spectrum disorder, and choroiditis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH18.

UniProtKB/Swiss-Prot: CAD10_HUMAN, Q9Y6N8
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

Gene Wiki entry for CDH10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_006576.17  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDH10 gene promoter:
         TBP   AML1a   FOXD1   Nkx2-5   POU6F1 (c2)   Evi-1   POU2F1   POU2F1b   POU2F1a   FOXO4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDH10 promoter sequence
   Search Chromatin IP Primers for CDH10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDH10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p14.2   Ensembl cytogenetic band:  5p14.1   HGNC cytogenetic band: 5p14.2

CDH10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDH10 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M024522:  view genomic region     (about GC identifiers)

Start:
24,487,209 bp from pter      End:
24,645,087 bp from pter
Size:
157,879 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CAD10_HUMAN, Q9Y6N8 (See protein sequence)
Recommended Name: Cadherin-10 precursor  
Size: 788 amino acids; 88451 Da
Secondary accessions: Q9ULB3

Explore the universe of human proteins at neXtProt for CDH10: NX_Q9Y6N8

Explore proteomics data for CDH10 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn256, Asn438, Asn456, Asn534
  • Modification sites at PhosphoSitePlus

  • See CDH10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006718.2  
    ENSEMBL proteins: 
     ENSP00000264463   ENSP00000425653  
    Reactome Protein details: Q9Y6N8

    CDH10 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MCDH: Cadherins / Major cadherins

    5 InterPro protein domains:
     IPR000233 Cadherin_cytoplasmic-dom
     IPR015919 Cadherin-like
     IPR020894 Cadherin_CS
     IPR027397 Catenin_binding_dom
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry Q9Y6N8

    ProtoNet protein and cluster: Q9Y6N8

    2 Blocks protein domains:
    IPB000233 Cadherin cytoplasmic region
    IPB002126 Cadherin


    UniProtKB/Swiss-Prot: CAD10_HUMAN, Q9Y6N8
    Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the
    connections, imparting a strong curvature to the full-length ectodomain (By similarity)
    Similarity: Contains 5 cadherin domains


    CDH10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAD10_HUMAN, Q9Y6N8
    Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in
    a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

         Genatlas biochemistry entry for CDH10:
    cadherin 10,T2 cadherin,transmembrane glycoprotein,component of adherens junction,predominantly expressed in
    brain,putatively involved in synaptic adhesions,axon outgrowth and guidance,also expressed in
    kidney,prostate,fetal lung

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    CDH10 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Cdh10 (no phenotypes)

    CDH10 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDH10
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CDH10 (see all 13):
    hsa-miR-374b* hsa-miR-3163 hsa-miR-203 hsa-miR-548d-3p hsa-miR-548am hsa-miR-589* hsa-let-7a-2* hsa-miR-587
    SwitchGear 3'UTR luciferase reporter plasmidCDH10 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CDH10

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CAD10_HUMAN, Q9Y6N8: Cell membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum3
    extracellular1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    CDH10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CDH10 About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Cell junction organization
    Cell junction organization0.70
    Cell-Cell communication0.64
    Cell-cell junction organization0.70
    Adherens junctions interactions0.49
    2ERK Signaling
    Rho Family GTPases0.61
    ILK Signaling0.49
    3Nanog in Mammalian ESC Pluripotency
    GSK3 Signaling0.61
    4WNT Signaling
    WNT Signaling
    5S-1P Stimulated Signaling
    S-1P Stimulated Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CDH10 (see all 7)
        S-1P Stimulated Signaling
    ILK Signaling
    GSK3 Signaling
    G12-G13 in Cellular Signaling
    Presenilin-Mediated Signaling

    1 Reactome Pathway for CDH10
        Adherens junctions interactions



    CDH10 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CDH10
    Interactions:

        Search GeneGlobe Interaction Network for CDH10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for CDH10 (Q9Y6N82, 3 ENSP000002644634) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS6Q7L5N12, 3MINT-65875 I2D: score=5 
    PTNP212462, 3MINT-65874 I2D: score=5 
    CDH9Q9ULB43, ENSP000002310214I2D: score=1 STRING: ENSP00000231021
    CDH6P552853, ENSP000002650714I2D: score=1 STRING: ENSP00000265071
    CTNNB1P352223, ENSP000003444564I2D: score=1 STRING: ENSP00000344456
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion IEA--
    GO:0016337cell-cell adhesion NAS10861224
    GO:0034329cell junction assembly TAS--
    GO:0034332adherens junction organization TAS--
    GO:0045216cell-cell junction organization TAS--

    CDH10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDH10 (CAD10)

    1 HMDB Compound for CDH10    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CDH10 gene (2 alternative transcripts): 
    NM_006727.3  NM_001190450.1  

    Unigene Cluster for CDH10:

    Cadherin 10, type 2 (T2-cadherin)
    Hs.92489  [show with all ESTs]
    Unigene Representative Sequence: NM_006727
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264463(uc003jgr.2 uc011cnu.2) ENST00000502921 ENST00000510477
    ENST00000503958
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CDH10 (see all 13):
    hsa-miR-374b* hsa-miR-3163 hsa-miR-203 hsa-miR-548d-3p hsa-miR-548am hsa-miR-589* hsa-let-7a-2* hsa-miR-587
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    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat CDH10

    Additional mRNA sequence: 

    AB035303.1 BC144168.1 

    2 DOTS entries:

    DT.409684  DT.99954351 

    Selected AceView cDNA sequences (see all 33):

    BX341579 CR615281 BX461563 NM_006727 AB035303 BM699076 BM669374 BM126883 
    D81558 F06652 BX478333 BU602361 BP348688 AW244041 AA211013 BP365688 
    F02926 R42804 D60075 BI033146 D60074 R17457 R42803 AF039747 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDH10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATGTTAGT
    CDH10 Expression
    About this image


    CDH10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Mature Choroid Plexus Cells Choroid Plexus
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
             Floor plate-like cells
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    CDH10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDH10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.92489

    UniProtKB/Swiss-Prot: CAD10_HUMAN, Q9Y6N8
    Tissue specificity: Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels
    detected in prostate and fetal lung

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDH10 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdh101 , 5 cadherin 101, 5 88.11(n)1
    96.83(a)1
      15 (8.20 cM)5
    3208731  NM_009865.21  NP_033995.11 
     188189475 
    chicken
    (Gallus gallus)
    Aves CDH101 cadherin 10, type 2 (T2-cadherin) 83.29(n)
    92.77(a)
      408049  NM_214673.1  NP_999838.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDH106
    cadherin 10, type 2 (T2-cadherin)
    90(a)
    1 ↔ 1
    GL343195.1(4462353-4611415)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cdh101 cadherin 10, type 2 (T2-cadherin) 75.1(n)
    83.74(a)
      100496218  XM_002935584.2  XP_002935630.2 
    zebrafish
    (Danio rerio)
    Actinopterygii cdh101 cadherin 10, type 2 (T2-cadherin) 65.09(n)
    65.04(a)
      568370  NM_001039633.1  NP_001034722.1 


    ENSEMBL Gene Tree for CDH10 (if available)
    TreeFam Gene Tree for CDH10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDH10 gene
    CDH182  CDH222  CDH192  CDH112  CDH72  CDH92  CDH62  CDH122  
    CDH82  CDH242  CDH202  CDH52  
    Selected SIMAP similar genes for CDH10 using alignment to 3 protein entries:     CAD10_HUMAN (see all proteins) (see all similar genes):
    CDH6    CDH18    Nbla04261    CDH20    CDH7    CDH11
    CDH8    CDH22    CDH9    CDH12    CDH19    CDH24
    CDH2    CDH5    CDH4    CDH1    FAT3    CDH3

    CDH10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDH10 (see all 3769)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361024
    A breast cancer sample4--see VAR_0361022 V L mis40--------
    rs1385336761,2
    Cuntested124509886(+) TGCTTC/TGACTT 2 K E mis11Minor allele frequency- T:0.00NA 4484
    rs11695611,2
    C,F,O,H--24486805(-) TATAGA/GGAATA 1 -- ds500130Minor allele frequency- G:0.14EA NA NS WA CSA 2918
    rs1382830981,2
    --24487017(+) TTTTCC/TACATA 1 -- ds50010--------
    rs1491973911,2
    --24487087(+) TAGCAC/TTTTCA 1 -- ds50010--------
    rs1862393101,2
    --24487303(+) GCACAA/GATGTC 1 -- ut310--------
    rs1433292711,2
    --24487322(+) AGGTTG/TCATAT 1 -- ut310--------
    rs1483848991,2
    C--24487458(+) AGAAGC/TGGCTT 1 -- ut310--------
    rs1915607771,2
    --24487473(+) GTGAGA/GTTGCT 1 -- ut310--------
    rs1378846531,2
    C,F--24487842(+) ATTCTC/TGGAGG 2 Q R mis11Minor allele frequency- T:0.00NA 4550

    HapMap Linkage Disequilibrium report for CDH10 (24487209 - 24645087 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CDH10 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670513CNV Deletion23128226
    esv2657466CNV Deletion23128226
    esv1416666CNV Insertion17803354
    nsv512848CNV Insertion21212237
    nsv4765CNV Insertion18451855
    nsv881402CNV Loss21882294
    nsv830236CNV Loss17160897
    esv25919CNV Loss19812545
    nsv880950CNV Loss21882294
    dgv5980n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604555    OMIM disorders: --

    10 diseases for CDH10:    
    About MalaCards
    autism spectrum disorder    choroiditis    breast and colorectal cancer    prostatitis
    prostate cancer    alzheimer's disease    endotheliitis    colorectal cancer
    hepatitis    cerebritis


    CDH10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CDH10
    Human Genome Epidemiology (HuGE) Navigator: CDH10 (2 documents)

    Export disorders for CDH10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDH10 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with CDH10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Common genetic variants on 5p14.1 associate with autism spectrum disorders. (PubMed id 19404256)1, 4, 9 Wang K....Hakonarson H. (Nature 2009)
    2. The human cadherin-10 gene: complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14. (PubMed id 10386616)1, 2, 9 Kools P.... van Roy F. (FEBS Lett. 1999)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. (PubMed id 19456320)1, 4 Ma D....Pericak-Vance M.A. (Ann. Hum. Genet. 2009)
    5. Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins. (PubMed id 10861224)1, 2 Shimoyama Y.... Natori M. (Biochem. J. 2000)
    6. Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue. (PubMed id 2059658)1, 3 Suzuki S.... Tanihara H. (Cell Regul. 1991)
    7. Genetic determinants of plasma I^a88-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain. (PubMed id 23279374)1 Athanasiadis G....Soria J.M. (J. Thromb. Haemost. 2013)
    8. Analysis of four genes involved in the neurodevelopment shows association of rs4307059 polymorphism in the cadherin 9/10 region with completed suicide. (PubMed id 22846907)1 Chojnicka I....PA8oski R. (Neuropsychobiology 2012)
    9. A genome-wide association study of serum uric acid in African Americans. (PubMed id 21294900)4 Charles B.A....Rotimi C.N. (BMC Med Genomics 2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1008 HGNC: 1749 AceView: CDH10 Ensembl:ENSG00000040731 euGenes: HUgn1008
    ECgene: CDH10 H-InvDB: CDH10

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDH10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDH10 gene:
    Search GeneIP for patents involving CDH10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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