Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CDCP2 Gene

Aliases for CDCP2 Gene

  • CUB Domain Containing Protein 2 2 3

External Ids for CDCP2 Gene

Summaries for CDCP2 Gene

GeneCards Summary for CDCP2 Gene

CDCP2 (CUB Domain Containing Protein 2) is a Protein Coding gene. An important paralog of this gene is TLL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDCP2 Gene

Genomics for CDCP2 Gene

Genomic Location for CDCP2 Gene

Start:
54,133,074 bp from pter
End:
54,153,770 bp from pter
Size:
20,697 bases
Orientation:
Minus strand

Genomic View for CDCP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CDCP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDCP2 Gene

Regulatory Elements for CDCP2 Gene

Proteins for CDCP2 Gene

  • Protein details for CDCP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VXM1-CDCP2_HUMAN
    Recommended name:
    CUB domain-containing protein 2
    Protein Accession:
    Q5VXM1
    Secondary Accessions:
    • Q6ZWJ3

    Protein attributes for CDCP2 Gene

    Size:
    449 amino acids
    Molecular mass:
    48752 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CDCP2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CDCP2 Gene

Proteomics data for CDCP2 Gene at MOPED

Post-translational modifications for CDCP2 Gene

  • Glycosylation at Asn40 and Asn267

Other Protein References for CDCP2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CDCP2 Gene

Domains for CDCP2 Gene

Protein Domains for CDCP2 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

CDCP2_HUMAN
Domain:
  • Contains 3 CUB domains.:
    • Q5VXM1
genes like me logo Genes that share domains with CDCP2: view

No data available for Gene Families for CDCP2 Gene

Function for CDCP2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CDCP2 Gene

Localization for CDCP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CDCP2 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CDCP2 Gene COMPARTMENTS Subcellular localization image for CDCP2 gene
Compartment Confidence
extracellular 3
plasma membrane 3
cytoskeleton 1
cytosol 1
golgi apparatus 1
nucleus 1

Gene Ontology (GO) - Cellular Components for CDCP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with CDCP2: view

Pathways for CDCP2 Gene

SuperPathways for CDCP2 Gene

No Data Available

Interacting Proteins for CDCP2 Gene

Gene Ontology (GO) - Biological Process for CDCP2 Gene

None

No data available for Pathways by source for CDCP2 Gene

Transcripts for CDCP2 Gene

mRNA/cDNA for CDCP2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(79) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CDCP2 Gene

CUB domain containing protein 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CDCP2 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14
SP1: - - - - - - - - - - -
SP2: - - - - -
SP3: - - - -
SP4: - - - - - - -
SP5: - -
SP6: -
SP7: - - - - -
SP8: - - - -
SP9:

Relevant External Links for CDCP2 Gene

GeneLoc Exon Structure for
CDCP2
ECgene alternative splicing isoforms for
CDCP2

Expression for CDCP2 Gene

mRNA expression in normal human tissues for CDCP2 Gene

mRNA differential expression in normal tissues according to GTEx for CDCP2 Gene

This gene is overexpressed in Spleen (7.4).

SOURCE GeneReport for Unigene cluster for CDCP2 Gene Hs.568555

genes like me logo Genes that share expressions with CDCP2: view

Orthologs for CDCP2 Gene

This gene was present in the common ancestor of animals.

Orthologs for CDCP2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CDCP2 36
  • 99.03 (n)
  • 98.66 (a)
CDCP2 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CDCP2 37
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CDCP2 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cdcp2 36
  • 86.88 (n)
  • 88.03 (a)
Cdcp2 16
Cdcp2 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CDCP2 37
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CDCP2 37
  • 61 (a)
OneToOne
chicken
(Gallus gallus)
Aves CDCP2 37
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CDCP2 37
  • 70 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii cdcp2 37
  • 42 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG32702 37
  • 3 (a)
ManyToMany
CG42255 37
  • 3 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea ZC116.3 37
  • 2 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 22 (a)
OneToOne
Species with no ortholog for CDCP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for CDCP2 Gene

ENSEMBL:
Gene Tree for CDCP2 (if available)
TreeFam:
Gene Tree for CDCP2 (if available)

Paralogs for CDCP2 Gene

Paralogs for CDCP2 Gene

Selected SIMAP similar genes for CDCP2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CDCP2: view

Variants for CDCP2 Gene

Sequence variations from dbSNP and Humsavar for CDCP2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs581554 -- 54,148,736(+) ttgta(C/T)taaaa intron-variant
rs583414 -- 54,149,109(-) ggacc(A/T)cagga intron-variant
rs585715 -- 54,149,664(+) gaatt(C/T)gtcac intron-variant
rs596611 -- 54,149,767(+) gcaag(C/T)accca intron-variant
rs599597 -- 54,143,979(-) TTCAC(A/G)GCTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CDCP2 Gene

Variant ID Type Subtype PubMed ID
nsv871920 CNV Gain 21882294
dgv44e199 CNV Deletion 23128226
esv24487 CNV Loss 19812545
dgv5n21 CNV Loss 19592680

Relevant External Links for CDCP2 Gene

HapMap Linkage Disequilibrium report
CDCP2

Disorders for CDCP2 Gene

Relevant External Links for CDCP2

Genetic Association Database (GAD)
CDCP2
Human Genome Epidemiology (HuGE) Navigator
CDCP2
genes like me logo Genes that share disorders with CDCP2: view

No data available for UniProtKB/Swiss-Prot for CDCP2 Gene

Publications for CDCP2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Investigation of the PARK10 gene in Parkinson disease. (PMID: 17388942) Li Y.J. … Vance J.M. (Ann. Hum. Genet. 2007) 3 49
  3. High-resolution whole-genome association study of Parkinson disease. (PMID: 16252231) Maraganore D.M. … Ballinger D.G. (Am. J. Hum. Genet. 2005) 49
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for CDCP2 Gene

Sources for CDCP2 Gene

Back to Top

Content