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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDCP1 Gene

protein-coding   GIFtS: 52
GCID: GC03M045123

CUB domain containing protein 1
 Explore 15 diseases affiliated with
CDCP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CDCP1    

Aliases
for CDCP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
CUB Domain Containing Protein 11 2     Transmembrane And Associated With Src Kinases2 3
SIMA1351 2 3 5     TRASK2 3
CD3181 2     CUB Domain-Containing Protein 12
Membrane Glycoprotein Gp1402 3     CD318 Antigen3
Subtractive Immunization M Plus HEp3-Associated 135 KDa Protein2 3     

External Ids:    HGNC: 243571   Entrez Gene: 648662   Ensembl: ENSG000001638147   OMIM: 6117355   UniProtKB: Q9H5V83   

Export aliases for CDCP1 gene to outside databases

Previous GC identifers: GC03M044303 GC03M044943 GC03M045084 GC03M045098


Summaries
for CDCP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CDCP1:
The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is
found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of
carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a
cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CDCP1_HUMAN, Q9H5V8
Function: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage
versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia
diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor
progression and metastasis

Gene Wiki entry for CDCP1


Genomic Views
for CDCP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDCP1 gene promoter:
         c-Fos   C/EBPbeta   AP-1   AML1a   JunB   Fra-1   FosB   PPAR-gamma1   PPAR-gamma2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CDCP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDCP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDCP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

CDCP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDCP1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M045123:  view genomic region     (about GC identifiers)

Start:
 45,123,769 bp from pter      End:
 45,187,914 bp from pter
Size:
 64,146 bases      Orientation:
 minus strand

Proteins
for CDCP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CDCP1_HUMAN, Q9H5V8 (See protein sequence)
Recommended Name: CUB domain-containing protein 1 precursor  
Size: 836 amino acids; 92932 Da
Subunit: Interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease
ST14/MT-SP1. Also interacts with SRC and PRKCG/protein kinase C gamma
Subcellular location: Isoform 1: Cell membrane; Single-pass membrane protein (Potential). Note=Shedding may also lead
to a soluble peptide
Subcellular location: Isoform 3: Secreted
Sequence caution: Sequence=BAB15388.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q49UB4 Q6NT71 Q6U9Y2 Q8WU91 Q96QU7 Q9H676 Q9H8C2
Alternative splicing: 3 isoforms:  Q9H5V8-1   Q9H5V8-2   Q9H5V8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDCP1: NX_Q9H5V8

Post-translational modifications:

  • Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C
    • gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog.
    Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-51
  • N-glycosylated1
  • A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa
    • (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal
    side. Converted to p80 by plasmin, a trypsin-like protease1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H5V8

    • CDCP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_073753.3  NP_835488.1  

    ENSEMBL proteins: 
     ENSP00000296129   ENSP00000399342  

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    Novus Biologicals CDCP1 Proteins
    Novus Biologicals CDCP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CDCP1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--


    CDCP1 for ontologies           About GeneDecksing



    CDCP1 Antibody Products: 
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    Protein Domains /
    Families
    for CDCP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CDCP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000859 CUB_dom

    Graphical View of Domain Structure for InterPro Entry Q9H5V8

    ProtoNet protein and cluster: Q9H5V8

    UniProtKB/Swiss-Prot: CDCP1_HUMAN, Q9H5V8
    Similarity: Contains 1 CUB domain


    Function
    for CDCP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CDCP1_HUMAN, Q9H5V8
    Function: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage
    versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia
    diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor
    progression and metastasis

    miRNA
    Products:            		miRTarBase miRNAs that target CDCP1:
    hsa-mir-30a (MIRT005178), hsa-mir-1 (MIRT001377)

    OriGene 3'-UTR Clone (see all 2): CDCP1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDCP1
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate CDCP1:
    hsa-miR-3163 hsa-miR-124 hsa-miR-198 hsa-miR-525-5p hsa-miR-506 hsa-miR-944 hsa-miR-520a-5p
    SwitchGear 3'UTR luciferase reporter plasmid: CDCP1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDCP1 (see all 7)
    OriGene shRNA RFP: CDCP1
    OriGene siRNA: CDCP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDCP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CDCP1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDCP1 (see all 4)
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    GenScript: all cDNA clones in your preferred vector (see all 2): CDCP1 (NM_178181)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDCP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDCP1 

    Cell Line
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    Search LifeMap BioReagents cell lines for CDCP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCP1

    Animal Models:
         Mouse knock-out Cdcp1tm1.2Moas for CDCP1
         1 MGI mutant phenotype (inferred from 2 alleles) (MGI details for Cdcp1):
     normal 

    CDCP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CDCP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Lymphocyte Signaling
    		Lymphocyte Signaling1.00
    2Adhesion
    		Adhesion1.00
    3Wnt / Hedgehog / Notch
    		Wnt / Hedgehog / Notch1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3 Cell Signaling Technology (CST) Pathways for CDCP1
        Wnt / Hedgehog / Notch
    Lymphocyte Signaling
    Adhesion



    CDCP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDCP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/10 Interacting proteins for CDCP1 (Q9H5V82, 3 ENSP000002961294) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKCDQ056552, 3, ENSP000003316024MINT-62341 MINT-62334 MINT-62336 MINT-62333 MINT-62332 MINT-62339 I2D: score=3 STRING: ENSP00000331602
    SRCP129312, 3, ENSP000003509414MINT-62337 MINT-62342 I2D: score=3 STRING: ENSP00000350941
    ST14Q9Y5Y63, ENSP000002787424I2D: score=1 STRING: ENSP00000278742
    PLGP007473, ENSP000003089384I2D: score=1 STRING: ENSP00000308938
    EGFRP005333, ENSP000002754934I2D: score=1 STRING: ENSP00000275493
    About this table

    Drugs & Compounds
    for CDCP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDCP1
    Search CenterWatch for drugs/clinical trials and news about CDCP1 

    Transcripts
    for CDCP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CDCP1 gene (2 alternative transcripts): 
    NM_022842.3  NM_178181.1  

    Unigene Cluster for CDCP1:

    CUB domain containing protein 1
    Hs.476093  [show with all ESTs]
    Unigene Representative Sequence: NM_022842
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296129(uc003com.3) ENST00000425231(uc003con.3) ENST00000490471


    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): CDCP1
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate CDCP1:
    hsa-miR-3163 hsa-miR-124 hsa-miR-198 hsa-miR-525-5p hsa-miR-506 hsa-miR-944 hsa-miR-520a-5p
    SwitchGear 3'UTR luciferase reporter plasmid: CDCP1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: CDCP1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDCP1
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDCP1
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    Additional cDNA sequence: 

    AF468010.1 AK023834.1 AK026187.1 AK026329.1 AK026622.1 AK314441.1 AY026461.1 AY167484.1 
    AY358779.1 AY375452.1 BC021099.1 BC069254.1 

    8 DOTS entries:

    DT.444481  DT.97861092  DT.100787843  DT.95271348  DT.100787841  DT.100787842  DT.426143  DT.97861080 

    24/176 AceView cDNA sequences (see all 176):

    BM840669 BM893690 CA307237 BC069254 CB157642 BM701518 AI202358 BM966953 
    AA554121 AI420501 NM_022842 CB129853 AA292689 BM044552 BX473477 BM966788 
    AA132854 BM840003 AA922764 BM893567 AI539070 BC021099 NM_178181 BQ962997 

    GeneLoc Exon Structure


    Expression
    for CDCP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDCP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCTTGGTAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CDCP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyUreteric BudUreteric Bud CellsKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    Line H7 (WA07) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See CDCP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDCP1

    SOURCE GeneReport for Unigene cluster: Hs.476093

    UniProtKB/Swiss-Prot: CDCP1_HUMAN, Q9H5V8
    Tissue specificity: Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels
    in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number
    of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells
    with phenotypes reminiscent of mesenchymal stem cells and neural stem cells

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    In Situ
    Assay Products:     
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    Orthologs
    for CDCP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CDCP1 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cdcp11 , 5 CUB domain containing protein 11, 5 82.51(n)1
    81.27(a)1    		   9 (73.92 cM)5
    1093321  NM_133974.31  NP_598735.21 
     1231708245 
    chicken
    (Gallus gallus)    		 Aves CDCP11 CUB domain containing protein 1 59.43(n)
    54.29(a)    		   420703  XM_418802.3  XP_418802.2 
    lizard
    (Anolis carolinensis)    		 Reptilia CDCP16
    		 --
    		 46(a)
    		 1 ↔ 1
    		 GL343611.1(252057-281052)
    zebrafish
    (Danio rerio)    		 Actinopterygii cdcp1a1 CUB domain containing protein 1a 41.7(n)
    26.62(a)    		   541520  NM_001014333.1  NP_001014355.1 


    ENSEMBL Gene Tree for CDCP1 (if available)
    TreeFam Gene Tree for CDCP1 (if available) 

    Paralogs
    for CDCP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for CDCP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1266 NCBI SNPs in CDCP1 are shown (see all 1266)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1417135381,2
    		--45123286(+) GAAAGA/GGGATT 1 -- ds50010--------
    rs1836552721,2
    		--45123334(+) AGATAC/TACAGT 1 -- ds50010--------
    rs1890984331,2
    		--45123455(+) ATCCAA/GTGTGC 1 -- ds50010--------
    rs1505593921,2
    		--45123496(+) GGTGGG/TGGCCA 1 -- ds50010--------
    rs765637811,2
    		F,--45123527(+) TGCTCT/GCCCTT 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1395937651,2
    		--45123541(+) TTTTGC/TTCTGG 1 -- ds50010--------
    rs1169855511,2
    		F,--45123593(+) AGTGAT/CTAGGG 1 -- ds50011Minor allele frequency- C:0.03EA 120
    rs1174081421,2
    		F,--45123686(+) GAACAG/AAACAA 1 -- ds50011Minor allele frequency- A:0.03EA 120
    rs1442683691,2
    		--45123693(+) ACAAGC/TCCTGG 1 -- ds50010--------
    rs1921099191,2
    		--45123818(+) TCTGCC/TTCACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CDCP1 (45123769 - 45187914 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for CDCP1
         1 CNV: 4333
         2 Indels: 27317 98298

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDCP1
    DNA2.0 Custom Variant and Variant Library Synthesis for CDCP1

    Disorders / Diseases
    for CDCP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CDCP1 for disorders           About GeneDecksing

    OMIM gene information: 611735    OMIM disorders: --

    15 diseases for CDCP1:    About MalaCards
    lung cancer    carcinoma    renal cell carcinoma    melanoma metastasis
    lung adenocarcinoma    peritonitis    pancreatic cancer    breast carcinoma
    colorectal cancer    melanoma    adenocarcinoma    prostate cancer
    pancreatitis    prostatitis    leukemia


    Export disorders for CDCP1 gene to outside databases

    Publications
    for CDCP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDCP1 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with CDCP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. (PubMed id 11466621)1, 2, 3 Scherl-Mostageer M.... Schweifer N. (2001)
    2. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. (PubMed id 14739293)1, 2, 9 Brown T.A.... Carter W.G. (2004)
    3. Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS. (PubMed id 16404722)1, 2, 9 Andre M.... Le Naour F. (2006)
    4. Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells. (PubMed id 17335815)1, 2 Perry S.E....Blair G.E. (2007)
    5. The C2 domain of PKCdelta is a phosphotyrosine binding domain. (PubMed id 15851033)1, 2 Benes C.H.... Soltoff S.P. (2005)
    6. Adhesion signaling by a novel mitotic substrate of src kinases. (PubMed id 16007225)1, 2 Bhatt A.S.... Moasser M.M. (2005)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. CDCP1 identifies a broad spectrum of normal and malignant stem/progenitor cell subsets of hematopoietic and nonhematopoietic origin. (PubMed id 15153610)1, 2 Buehring H.-J....Lammers R. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. CDCP1 is a novel marker for hematopoietic stem cells. (PubMed id 12799299)1, 2 Conze T.... Buehring H.-J. (2003)

    External Searches for CDCP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CDCP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64866 HGNC: 24357 AceView: CDCP1 Ensembl:ENSG00000163814 euGenes: HUgn64866
    ECgene: CDCP1 H-InvDB: CDCP1

    Other Databases showing CDCP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CDCP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDCP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CDCP1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for CDCP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CDCP1 gene:
    Search GeneIP for patents involving CDCP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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