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CDCA7L Gene

protein-coding   GIFtS: 52
GCID: GC07M021907

Cell Division Cycle Associated 7-Like

  Search for CDCA7L
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cell Division Cycle Associated 7-Like1 2     RAM22
JPO22 3 5     Cell Division Cycle-Associated 7-Like Protein2
R12 3 5     HR13
Transcription Factor RAM22 3     Protein JPO23

External Ids:    HGNC: 307771   Entrez Gene: 555362   Ensembl: ENSG000001646497   OMIM: 6096855   UniProtKB: Q96GN53   

Export aliases for CDCA7L gene to outside databases

Previous GC identifer: GC07M021714


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CDCA7L Gene:
CDCA7L (cell division cycle associated 7-like) is a protein-coding gene. An important paralog of this gene is CDCA7.

UniProtKB/Swiss-Prot: CDA7L_HUMAN, Q96GN5
Function: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA)
activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full
transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream
of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1

Gene Wiki entry for CDCA7L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CDCA7L gene promoter:
         MZF-1   FAC1   Sp1   AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CDCA7L promoter sequence
   Search Chromatin IP Primers for CDCA7L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDCA7L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.3   Ensembl cytogenetic band:  7p15.3   HGNC cytogenetic band: 7p15.3

CDCA7L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDCA7L gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M021907:  view genomic region     (about GC identifiers)

Start:
21,940,517 bp from pter      End:
21,985,702 bp from pter
Size:
45,186 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 21,991,889-22,036,870     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CDA7L_HUMAN, Q96GN5 (See protein sequence)
Recommended Name: Cell division cycle-associated 7-like protein  
Size: 454 amino acids; 52206 Da
Subunit: Interacts with MYC and PSIP1
Miscellaneous: Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell
lines. CDCA7L overexpression induces colony formation
Sequence caution: Sequence=BAB14330.1; Type=Frameshift; Positions=260;
Secondary accessions: A4D141 A6NF50 B3KTR5 B4DUT3 C9K0Y1 Q6PIL4 Q86YT0 Q8IXN5 Q96C70 Q9H9A2
Q9NPV2
Alternative splicing: 4 isoforms:  Q96GN5-1   Q96GN5-2   Q96GN5-4   Q96GN5-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDCA7L: NX_Q96GN5

Explore proteomics data for CDCA7L at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys63, Lys280, Lys347, Lys440
  • Modification sites at PhosphoSitePlus

  • See CDCA7L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001120842.1  NP_001120843.1  NP_061189.2  

    ENSEMBL proteins: 
     ENSP00000348523   ENSP00000383986   ENSP00000363045   ENSP00000400673   ENSP00000406616  
     ENSP00000411337   ENSP00000410014  

    CDCA7L Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for CDCA7L

     
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    Search eBioscience for ELISAs for CDCA7L 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR018866 Znf-4CXXC_R1

    Graphical View of Domain Structure for InterPro Entry Q96GN5

    ProtoNet protein and cluster: Q96GN5


    Find genes that share domains with CDCA7L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CDA7L_HUMAN, Q96GN5
    Function: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA)
    activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full
    transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream
    of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1
    Induction: By MYC overexpression in a concentration dependent manner in neuroblastoma cell line

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDCA7L
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDCA7L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDCA7L

    miRNA
    Products:
        
    miRTarBase miRNAs that target CDCA7L:
    hsa-mir-124-3p (MIRT002722), hsa-mir-375 (MIRT019850), hsa-mir-484 (MIRT041933)

    Block miRNA regulation of human, mouse, rat CDCA7L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CDCA7L (see all 36):
    hsa-miR-15a hsa-miR-25 hsa-miR-218 hsa-miR-424 hsa-miR-4325 hsa-miR-15b hsa-miR-761 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidCDCA7L 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat CDCA7L

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): CDCA7L (NM_001127370)
    Sino Biological Human cDNA Clone for CDCA7L
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDCA7L

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA7L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CDA7L_HUMAN, Q96GN5: Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus
    under dexamethasone induction
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with CDCA7L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CDCA7L About    
    See pathways by source

    SuperPathContained pathways About
    1SIDS Susceptibility Pathways
    SIDS Susceptibility Pathways


    1 BioSystems Pathway for CDCA7L
        SIDS Susceptibility Pathways



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CDCA7L
    Interactions:

        GeneGlobe Interaction Network for CDCA7L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for CDCA7L (Q96GN53 ENSP000003839864) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    ZGPATQ8N5A53I2D: score=1 
    CCNB1ENSP000002564424STRING: ENSP00000256442
    CCNE1ENSP000002626434STRING: ENSP00000262643
    CDC6ENSP000002097284STRING: ENSP00000209728
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0008284positive regulation of cell proliferation IDA15994933

    Find genes that share ontologies with CDCA7L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDCA7L (CDA7L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CDCA7L gene (3 alternative transcripts): 
    NM_001127370.2  NM_001127371.2  NM_018719.4  

    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356195(uc003sve.4) ENST00000488845 ENST00000406877(uc010kuk.3 uc010kul.3 uc003svf.4)
    ENST00000373934 ENST00000435717 ENST00000489669 ENST00000465490 ENST00000457951
    ENST00000447180 ENST00000435031
    miRNA
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    Block miRNA regulation of human, mouse, rat CDCA7L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CDCA7L (see all 36):
    hsa-miR-15a hsa-miR-25 hsa-miR-218 hsa-miR-424 hsa-miR-4325 hsa-miR-15b hsa-miR-761 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidCDCA7L 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CDCA7L
    Predesigned siRNA for gene silencing in human, mouse, rat CDCA7L
    Clone
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    OriGene ORF clones in mouse, rat for CDCA7L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): CDCA7L (NM_001127370)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDCA7L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDCA7L
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CDCA7L
    OriGene qSTAR qPCR primer pairs in human, mouse for CDCA7L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CDCA7L
      QuantiTect SYBR Green Assays in human, mouse, rat CDCA7L
      QuantiFast Probe-based Assays in human, mouse, rat CDCA7L

    Selected AceView cDNA sequences (see all 225):

    AA296517 AY161168 AU131537 AA258503 AA186390 BI753220 AL527140 BX422040 
    CA406280 AI589780 AW273839 AU154195 AI625961 AI222288 CB142010 BU753973 
    CB159644 AI242371 AL553959 BQ051701 BQ221409 BM480300 CB159130 AI333578 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CDCA7L (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10
    SP1:                                                                                      -               
    SP2:                                                                                      -               
    SP3:                                                                                                      
    SP4:                          -                                                                           
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for CDCA7L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDCA7L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAGCTCCTT
    CDCA7L Expression
    About this image


    CDCA7L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 3 entries
             Hindgut
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 3 entries
             Human embryonic stem cells (family)
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Neural Tube (Nervous System)
             Mesencephalic Ventricular Zone
    CDCA7L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDCA7L Protein Expression

    UniProtKB/Swiss-Prot: CDA7L_HUMAN, Q96GN5
    Tissue specificity: Ubiquitous. Overexpressed in medulloblastoma

        Custom PCR Arrays for CDCA7L
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA7L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDCA7L gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdca7l1 , 5 cell division cycle associated 7 like1, 5 80.2(n)1
    80.5(a)1
      12 (63.20 cM)5
    2179461  NM_146040.11  NP_666152.11 
     1178042895 
    chicken
    (Gallus gallus)
    Aves CDCA7L1 cell division cycle associated 7-like 66.96(n)
    68.99(a)
      420608  NM_001030982.1  NP_001026153.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDCA7L6
    cell division cycle associated 7-like
    60(a)
    1 ↔ 1
    6(29972295-29995822)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.49102 Xenopus laevis transcribed sequence with weak similarity more 74.17(n)    BU906026.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cdca7b1 cell division cycle associated 7b 52.44(n)
    48.74(a)
      572007  XM_002665462.3  XP_002665508.2 


    ENSEMBL Gene Tree for CDCA7L (if available)
    TreeFam Gene Tree for CDCA7L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDCA7L gene
    CDCA72  
    1 SIMAP similar gene for CDCA7L using alignment to 5 protein entries:     CDA7L_HUMAN (see all proteins):
    CDCA7

    Find genes that share paralogs with CDCA7L           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CDCA7L
    PGOHUM00000249317


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDCA7L (see all 1241)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1138604571,2
    C--21941376(+) AGGCC-/TC    
       CAGTG
    TCCAG
    3 -- ut311Minor allele frequency- TCCAGTG:0.50CSA 2
    rs572080601,2
    C--21941378(+) GTGTC-/CA    
       GTGTC
    TACAA
    3 -- ut312Minor allele frequency- CAGTGTC:0.09NA NS 334
    rs568840631,2
    C--21941586(+) GCCAA-/AGAT  
            
    AGATA
    3 -- ut313Minor allele frequency- AGAT:0.07NA NS CSA 328
    rs1896673991,2
    C--21941983(+) AAAGAT/AGAGAA 3 -- int11Minor allele frequency- A:0.00EU 1323
    rs1808986441,2
    --21942029(+) TTCTAC/GGCTTG 3 -- int10--------
    rs1453097581,2
    --21942037(+) TTGAGA/TGATTC 3 -- int10--------
    rs69655831,2
    C,F,H--21942120(+) ATATCC/TGTATA 3 -- int113Minor allele frequency- T:0.04NS EA NA WA 1762
    rs772981681,2
    C,F--21942142(+) AGTACG/ACCCCA 3 -- int11Minor allele frequency- A:0.06WA 118
    rs1433397161,2
    --21942148(+) CCCCAA/GGCATG 3 -- int10--------
    rs1414580321,2
    C--21942183(+) ACCAC-/GATTCAG
    AGTTTATTA
    GATTC
    3 -- int10--------

    HapMap Linkage Disequilibrium report for CDCA7L (21940517 - 21985702 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CDCA7L:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv275068CNV Loss21479260
    nsv830922CNV Loss17160897
    nsv7393OTHER Inversion18451855

    Human Gene Mutation Database (HGMD): CDCA7L
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CDCA7L
    DNA2.0 Custom Variant and Variant Library Synthesis for CDCA7L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609685    OMIM disorders: --


    Find genes that share disorders with CDCA7L           About GenesLikeMe

    Genetic Association Database (GAD): CDCA7L

    Export disorders for CDCA7L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDCA7L gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with CDCA7L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway. (PubMed id 16829576)1, 2, 3 Ou X.-M.... Shih J.C. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    2. R1, a novel repressor of the human monoamine oxidase A. (PubMed id 15654081)1, 2, 9 Chen K.... Shih J.C. (J. Biol. Chem. 2005)
    3. A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. (PubMed id 20189936)1, 4 Okada Y....Kamatani N. (Hum. Mol. Genet. 2010)
    4. Transcriptional co-activator p75 binds and tethers the Myc- interacting protein JPO2 to chromatin. (PubMed id 16735438)1, 2 Maertens G.N.... Engelman A. (J. Cell Sci. 2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1. (PubMed id 16728402)1, 2 Ou X.-M.... Shih J.C. (J. Biol. Chem. 2006)
    7. Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells. (PubMed id 15994933)1, 2 Huang A.... Penn L.Z. (Cancer Res. 2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55536 HGNC: 30777 AceView: RAM2 Ensembl:ENSG00000164649 euGenes: HUgn55536
    ECgene: CDCA7L H-InvDB: CDCA7L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDCA7L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDCA7L gene:
    Search GeneIP for patents involving CDCA7L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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