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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDCA5 Gene

protein-coding   GIFtS: 58
GCID: GC11M064833

Cell Division Cycle Associated 5

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cell Division Cycle Associated 51 2
sororin1 2
Cell Division Cycle-Associated Protein 52 3
p352 3
SORORIN2 5

External Ids:    HGNC: 146261   Entrez Gene: 1131302   Ensembl: ENSG000001466707   OMIM: 6093745   UniProtKB: Q96FF93   

Export aliases for CDCA5 gene to outside databases

Previous GC identifers: GC11U990624 GC11M065095 GC11M064620 GC11M064601 GC11M064844 GC11M061171


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CDCA5 Gene: 
CDCA5 (cell division cycle associated 5) is a protein-coding gene. Diseases associated with CDCA5 include roberts syndrome, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include protein binding and chromatin binding.

UniProtKB/Swiss-Prot: CDCA5_HUMAN, Q96FF9
Function: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with
chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion
ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in
DNA repair. Required for efficient DNA double-stranded break repair

Gene Wiki entry for CDCA5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDCA5 gene promoter:
         SRF   ISGF-3   p53   SRF (504 AA)   FOXO1a   Pax-4a   C/EBPalpha   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDCA5 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDCA5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDCA5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.1   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13.1

CDCA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDCA5 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M064833:  view genomic region     (about GC identifiers)

Start:
64,833,772 bp from pter      End:
64,851,636 bp from pter
Size:
17,865 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CDCA5_HUMAN, Q96FF9 (See protein sequence)
Recommended Name: Sororin  
Size: 252 amino acids; 27601 Da
Subunit: Interacts with the APC/C complex (By similarity). Interacts with the chromatin-bound cohesin complex; the
interaction is indirect, occurs after DNA replication and requires acetylation of the cohesin component SMC3.
Interacts (via the FGF motif) with PDS5A and PDS5B; the interaction is direct and prevents the interaction of
PDS5A with WAPAL
Subcellular location: Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until
metaphase and is released in the cytoplasm upon nuclear envelope breakdown
Miscellaneous: Named sororin after the Latin word 'soror', which means 'sister', because of its critical role in
sister chromatid cohesion
Secondary accessions: A8K625

Explore the universe of human proteins at neXtProt for CDCA5: NX_Q96FF9

Explore proteomics data for CDCA5 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the
    inhibition of WAPAL by CDCA5
  • UniProtKB: Ubiquitinated by the APC/C complex in G1, leading to its degradation (Probable)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96FF9

  • CDCA5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CDCA5 Protein Expression
    REFSEQ proteins: NP_542399.1  
    ENSEMBL proteins: 
     ENSP00000432183   ENSP00000432342   ENSP00000275517   ENSP00000431888   ENSP00000385711  
     ENSP00000432621   ENSP00000414881  
    Reactome Protein details: Q96FF9
    Human Recombinant Protein Products for CDCA5: 
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    Novus Biologicals CDCA5 Protein
    Novus Biologicals CDCA5 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CDCA5 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region TAS--
    GO:0000790nuclear chromatin ISS--
    GO:0005634nucleus ISS--
    GO:0005654nucleoplasm TAS--
    GO:0005694chromosome TAS--

    CDCA5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR018605 Sororin

    Graphical View of Domain Structure for InterPro Entry Q96FF9

    ProtoNet protein and cluster: Q96FF9

    UniProtKB/Swiss-Prot: CDCA5_HUMAN, Q96FF9
    Domain: The KEN box is required for the association with the APC/C complex (By similarity)
    Similarity: Belongs to the sororin family


    CDCA5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CDCA5_HUMAN, Q96FF9
    Function: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with
    chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion
    ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in
    DNA repair. Required for efficient DNA double-stranded break repair

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding TAS15837422
    GO:0005515protein binding IPI--
         
    CDCA5 for ontologies           About GeneDecksing


    Phenotypes:
         11 GenomeRNAi human phenotypes for CDCA5:
     Abundance of large cells with   Cell cycle / mitosis defect  Cell division defect  Decreased cell number, increas 
     Decreased viability of wild-ty  Increased Salmonella enterica   Increased cell death in breast  Increased cell number in G2M,  
     Increased gamma-H2AX phosphory  Increased number of cells in m  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CDCA5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CDCA5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDCA5 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDCA5 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDCA5
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate CDCA5:
    hsa-miR-221* hsa-miR-1321 hsa-miR-4286 hsa-let-7g* hsa-let-7a-2* hsa-miR-1286 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidCDCA5 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CDCA5 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4CDK-mediated phosphorylation and removal of Cdc6
    S Phase0.79
    5Cohesin Loading onto Chromatin
    Establishment of Sister Chromatid Cohesion0.62

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/11        Reactome Pathways for CDCA5 (see all 11)
        Mitotic Metaphase and Anaphase
    Establishment of Sister Chromatid Cohesion
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase


    1         Kegg Pathway  (Kegg details for CDCA5):
        MicroRNAs in cancer


    CDCA5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDCA5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/22 Interacting proteins for CDCA5 (Q96FF91, 2, 3 ENSP000002755174) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    XRCC6P129562, 3, ENSP000003522574MINT-65145 I2D: score=5 STRING: ENSP00000352257
    PDS5AQ29RF71, 3, ENSP000003034274EBI-718805,EBI-1175454 I2D: score=2 STRING: ENSP00000303427
    SMC3Q9UQE73, ENSP000003547204I2D: score=2 STRING: ENSP00000354720
    PDS5BQ9NTI53, ENSP000003138514I2D: score=2 STRING: ENSP00000313851
    RAD21O602163, ENSP000002973384I2D: score=1 STRING: ENSP00000297338
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000082G1/S transition of mitotic cell cycle IDA15837422
    GO:0000278mitotic cell cycle TAS--
    GO:0006302double-strand break repair IMP17349791
    GO:0007064mitotic sister chromatid cohesion IMP17349791
    GO:0007067mitosis IDA15837422

    CDCA5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDCA5

    Search CenterWatch for drugs/clinical trials and news about CDCA5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CDCA5 gene: 
    NM_080668.3  

    Unigene Cluster for CDCA5:

    Cell division cycle associated 5
    Hs.434886  [show with all ESTs]
    Unigene Representative Sequence: NM_080668
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529290 ENST00000525464 ENST00000533015 ENST00000275517(uc001ocp.2)
    ENST00000524733 ENST00000404147 ENST00000479032 ENST00000531401 ENST00000527430
    ENST00000462902 ENST00000438878(uc001oco.3)
    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate CDCA5:
    hsa-miR-221* hsa-miR-1321 hsa-miR-4286 hsa-let-7g* hsa-let-7a-2* hsa-miR-1286 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidCDCA5 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: CDCA5 (NM_080668)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDCA5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDCA5
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    OriGene qPCR primer pairs and template standards for CDCA5
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDCA5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDCA5

    Additional mRNA sequence: 

    AK093670.1 AK291490.1 AL832526.1 BC011000.2 

    8 DOTS entries:

    DT.443629  DT.100802249  DT.95254179  DT.92452053  DT.95227834  DT.101979301  DT.91685179  DT.92452047 

    24/311 AceView cDNA sequences (see all 311):

    BU557980 BM480129 BQ438240 BG114326 AA631344 AA627087 BQ953112 AI138924 
    BQ064533 AA662530 AI097444 AF055882 NM_080668 BM982693 AW615722 AL517732 
    BI226126 AW166947 BM699162 BQ441652 BM554537 AA588878 BE563266 AL832526 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CDCA5    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6
    SP1:                    -                             -               
    SP2:                    -     -                                       
    SP3:                                                                  
    SP4:                                                                  


    ECgene alternative splicing isoforms for CDCA5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDCA5 expression in normal human tissues (normalized intensities)      CDCA5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCTCTGGAG
    CDCA5 Expression
    About this image


    CDCA5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/17 selected tissues (see all 17) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Thalamus
             Human Cerebellar Astrocytes   
             brain/midbrain   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
     
     Smooth Muscle (Muscoskeletal System)
             Human Intestinal Smooth Muscle Cells (HISMC)   
     
     Thymus (Hematopoietic System)
             Thymus
     
     Gut Tube (Gastrointestinal Tract)
             Foregut

    See CDCA5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDCA5

    SOURCE GeneReport for Unigene cluster: Hs.434886
        SABiosciences Custom PCR Arrays for CDCA5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CDCA5 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdca51 , 5 cell division cycle associated 51, 5 75.17(n)1
    72.06(a)1
      19 (4.34 cM)5
    678491  NM_026410.31  NP_080686.11 
     60849835 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    39(a)
    31(a)
    many → 1
    many → 1
    AAWZ02037296(209-3214)
    1(233984011-233985191)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.129222 Xenopus laevis transcribed sequence with weak similarity more 77.17(n)    BJ075269.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cdca56
    cell division cycle associated 5
    24(a)
    1 ↔ 1
    5(70170756-70176273)


    ENSEMBL Gene Tree for CDCA5 (if available)
    TreeFam Gene Tree for CDCA5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/110 SNPs in CDCA5 are shown (see all 110)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1422341041,2
    C--64844673(+) AGAATC/TGCTTG 1 -- int10--------
    rs11526081,2
    C,H--64844809(+) GAATGG/CGGGGA 1 -- int18Minor allele frequency- C:0.07NA WA CSA 15
    rs1844307781,2
    C--64844829(+) GGGAGC/TGCCTG 1 -- int10--------
    rs1123401131,2
    F--64844887(+) ACCTTC/TGGCTC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1411663281,2
    --64845094(+) GAGTTC/GTGCTG 1 -- ut310--------
    rs1469457871,2
    C--64845202(+) AGAGCA/GTTGAG 1 -- ut310--------
    rs1475952221,2
    --64845217(+) TGGCCC/TGGGAC 1 -- ut310--------
    rs1425047691,2
    C--64845256(+) GGCCCA/GCCTGG 1 -- ut310--------
    rs1502417541,2
    C--64845436(+) AAATCC/GACACT 1 -- ut310--------
    rs4894891,2
    C,F,A,H--64845438(+) ATCCAC/AACTAT 1 -- ut31 ese328Minor allele frequency- A:0.25MN EA NA NS WA CSA 4312

    HapMap Linkage Disequilibrium report for CDCA5 (64833772 - 64851636 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CDCA5:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv1174n71CNV Loss21882294
    nsv526181CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609374    OMIM disorders: --

    2 diseases for CDCA5:    About MalaCards
    roberts syndrome    

    1 disease from the University of Copenhagen DISEASES database for CDCA5:
    Roberts syndrome

    CDCA5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CDCA5
    Human Genome Epidemiology (HuGE) Navigator: CDCA5 (1 document)

    Export disorders for CDCA5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDCA5 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with CDCA5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates. (PubMed id 15837422)1, 2, 3, 9 Rankin S.... Kirschner M.W. (2005)
    2. Drug target discovery by gene expression analysis: cell cycle genes. (PubMed id 12188893)1, 2, 3 Walker M.G. (2001)
    3. Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. (PubMed id 17349791)1, 2, 9 Schmitz J....Peters J.M. (2007)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Sororin mediates sister chromatid cohesion by antagonizing wapl. (PubMed id 21111234)1, 2 Nishiyama T....Peters J.M. (2010)
    6. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Regulation of centromeric cohesion by sororin independently of the APC/C. (PubMed id 17361102)1, 9 Diaz-Martinez L.A....Clarke D.J. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 113130 HGNC: 14626 AceView: CDCA5 Ensembl:ENSG00000146670 euGenes: HUgn113130
    ECgene: CDCA5 Kegg: 113130 H-InvDB: CDCA5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDCA5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CDCA5 gene:
    Search GeneIP for patents involving CDCA5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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