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CDCA3 Gene

protein-coding   GIFtS: 55
GCID: GC12M006960

Cell Division Cycle Associated 3

  See CDCA3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Cell Division Cycle Associated 31 2     TOME-12 3
Trigger Of Mitotic Entry 11 2     Cell Division Cycle-Associated Protein 32
Gene-Rich Cluster Protein C82 3     Gene Rich Cluster, C82
Trigger Of Mitotic Entry Protein 12 3     C83
GRCC82 3     TOME13

External Ids:    HGNC: 146241   Entrez Gene: 834612   Ensembl: ENSG000001116657   OMIM: 6077495   UniProtKB: Q996183   
ORGUL members:         

Export aliases for CDCA3 gene to outside databases

Previous GC identifers: GC12U990228 GC12M006833 GC12M006828 GC12M006959


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CDCA3 Gene:
CDCA3 (cell division cycle associated 3) is a protein-coding gene. Diseases associated with CDCA3 include clonorchiasis.

UniProtKB/Swiss-Prot: CDCA3_HUMAN, Q99618
Function: F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase
complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity)

Gene Wiki entry for CDCA3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_009759.17  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDCA3 gene promoter:
         c-Fos   AP-1   ATF-2   GATA-2   c-Ets-1   PPAR-gamma1   c-Jun   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDCA3 promoter sequence
   Search Chromatin IP Primers for CDCA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDCA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.31

CDCA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDCA3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M006960:  view genomic region     (about GC identifiers)

Start:
6,953,957 bp from pter      End:
6,961,230 bp from pter
Size:
7,274 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CDCA3_HUMAN, Q99618 (See protein sequence)
Recommended Name: Cell division cycle-associated protein 3  
Size: 268 amino acids; 28998 Da
Subunit: Interacts with SKP1. Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity)
Secondary accessions: A8K5V6 D3DUS6

Explore the universe of human proteins at neXtProt for CDCA3: NX_Q99618

Explore proteomics data for CDCA3 at MOPED

Post-translational modifications: 

  • Ubiquitinated and degraded by the APC/C-Cdh1 complex (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CDCA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112589.1  
    ENSEMBL proteins: 
     ENSP00000415142   ENSP00000442068   ENSP00000229265   ENSP00000446339   ENSP00000441120  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q99618

    UniProtKB/Swiss-Prot: CDCA3_HUMAN, Q99618
    Domain: The KEN box is required for the association with the APC/C-Cdh1 complex (By similarity)


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CDCA3_HUMAN, Q99618
    Function: F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase
    complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with CDCA3           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for CDCA3:
     Decreased nuclei size in G2M  Synthetic lethal with Ras  Upregulation of Wnt/beta-caten 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDCA3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CDCA3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDCA3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDCA3

    miRNA
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    miRTarBase miRNAs that target CDCA3:
    hsa-mir-26b-5p (MIRT029492), hsa-let-7e-5p (MIRT051450), hsa-mir-320a (MIRT044752)

    Block miRNA regulation of human, mouse, rat CDCA3 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CDCA3:
    hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidCDCA3 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat CDCA3

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CDCA3_HUMAN, Q99618: Cytoplasm, cytosol (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    extracellular1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005829cytosol IEA--

    Find genes that share ontologies with CDCA3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CDCA3 About    
    See pathways by source

    SuperPathContained pathways About
    1Cell cycle Role of APC in cell cycle regulation
    Cell cycle Role of APC in cell cycle regulation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for CDCA3
        Cell cycle Role of APC in cell cycle regulation


    UniProtKB/Swiss-Prot: CDCA3_HUMAN, Q99618
    Pathway: Protein modification; protein ubiquitination

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CDCA3
    Interactions:

        Search GeneGlobe Interaction Network for CDCA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for CDCA3 (Q996182, 3 ENSP000002292654) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTDSP1Q9GZU72, 3, ENSP000002730624MINT-68177 I2D: score=5 STRING: ENSP00000273062
    CUL1Q136163, ENSP000003268044I2D: score=2 STRING: ENSP00000326804
    SKP1P632083, ENSP000002314874I2D: score=3 STRING: ENSP00000231487
    WEE1P302913, ENSP000004020844I2D: score=2 STRING: ENSP00000402084
    TRAF2Q129333, ENSP000002476684I2D: score=5 STRING: ENSP00000247668
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0008150biological_process ND--
    GO:0016567protein ubiquitination IEA--

    Find genes that share ontologies with CDCA3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDCA3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CDCA3 gene: 
    NM_031299.4  

    Unigene Cluster for CDCA3:

    Cell division cycle associated 3
    Hs.524216  [show with all ESTs]
    Unigene Representative Sequence: AK093805
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000422785(uc001qre.2 uc001qrf.1) ENST00000604599 ENST00000603043
    ENST00000538862(uc001qrg.2) ENST00000229265 ENST00000535406 ENST00000536241
    ENST00000544610 ENST00000540683 ENST00000545368 ENST00000535871 ENST00000446553

    miRNA
    Products:
         
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    1 qRT-PCR Assays for microRNA that regulate CDCA3:
    hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidCDCA3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CDCA3
    Predesigned siRNA for gene silencing in human, mouse, rat CDCA3
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CDCA3 (NM_031299)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDCA3
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    Primer
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    OriGene qPCR primer pairs and template standards for CDCA3
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CDCA3
      QuantiTect SYBR Green Assays in human, mouse, rat CDCA3
      QuantiFast Probe-based Assays in human, mouse, rat CDCA3

    Additional mRNA sequence: 

    AK092246.1 AK093805.1 AK291421.1 AK312843.1 BC002551.2 

    16 DOTS entries:

    DT.92416888  DT.97762970  DT.100815685  DT.91750091  DT.215631  DT.121170331  DT.99997195  DT.100036324 
    DT.100815684  DT.97858771  DT.97858769  DT.100682771  DT.87005421  DT.100822900  DT.121170390  DT.40115198 

    Selected AceView cDNA sequences (see all 164):

    CA421440 AI336973 AI123342 CB162837 C02097 AA634371 BM559656 BQ018083 
    CR621398 AA282052 BC002551 BM969047 BX099267 BQ938188 BF001726 AA767991 
    BM559654 BM840444 AK097957 BQ428501 BE739240 BM555245 AA257078 CB112373 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CDCA3 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f
    SP1:                                                        -                       -                                                   
    SP2:                                                        -     -                 -                                                   
    SP3:                                            -     -     -     -     -           -                                                   
    SP4:                                                        -                       -     -                                             
    SP5:                                      -                 -                       -     -     -                                       


    ECgene alternative splicing isoforms for CDCA3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDCA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCAGCAA
    CDCA3 Expression
    About this image


    CDCA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Mesencephalic Ventricular Zone
     
     Thymus (Hematopoietic System)
             Double Negative 2 Thymocytes Thymus
     
     Blood (Cardiovascular System)
             Double Negative 2 Thymocytes Thymus
     
     Brain (Nervous System)
             Hypothalamus
    CDCA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDCA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.524216
        Custom PCR Arrays for CDCA3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDCA3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdca31 , 5 cell division cycle associated 31, 5 81.45(n)1
    73.31(a)1
      6 (59.17 cM)5
    147931  NM_013538.51  NP_038566.11 
     1248295475 
    chicken
    (Gallus gallus)
    Aves CDCA31 cell division cycle associated 3 54.65(n)
    48.65(a)
      770517  NM_001278136.1  NP_001265065.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    51(a)
    39(a)
    1 ↔ many
    1 ↔ many
    GL343297.1(1190478-1190711)
    GL343453.1(407014-423085)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cdca31 cell division cycle associated 3 48.07(n)
    40.62(a)
      100379776  XM_004915778.1  XP_004915835.1 


    ENSEMBL Gene Tree for CDCA3 (if available)
    TreeFam Gene Tree for CDCA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDCA3 gene

    Find genes that share paralogs with CDCA3           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CDCA3
    PGOHUM00000233189


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDCA3 (see all 51)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1900187751,2
    --6957632(+) TTGGTA/GGCTGG 1 -- ds50010--------
    rs1150170351,2
    C,F--6957997(+) TACCTT/CTTTAA 1 -- ut311Minor allele frequency- C:0.02WA 118
    rs1137608771,2
    C--6958162(+) ACAGAT/CATCAC 1 -- ut311Minor allele frequency- C:0.00EU 500
    rs2017944091,2
    --6958177(+) CCCTGA/GGTGAC 1 -- ut310--------
    rs2010265951,2
    --6958178(+) CCTGGA/GTGACT 1 -- ut310--------
    rs617331721,2
    C,F--6958257(+) CTGGCC/TTTGCT 2 S G mis12Minor allele frequency- T:0.00NS NA 4628
    rs110644281,2
    C--6958261(+) CCTTGC/TTCCCA 2 E syn12Minor allele frequency- T:0.00NA 4
    rs1499211531,2
    C--6958277(+) GTCCTC/TCAGTT 2 E G mis10--------
    rs2008846601,2
    --6958292(+) GAAGTA/CGTCCA 2 R L mis10--------
    rs1481724761,2
    C,F--6958356(+) AGGCCG/ACTTAC 2 /R /W mis11Minor allele frequency- A:0.00NA 4550

    HapMap Linkage Disequilibrium report for CDCA3 (6953957 - 6961230 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CDCA3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv898641CNV Loss21882294
    dgv1353n71CNV Loss21882294
    nsv832323CNV Loss17160897
    nsv832324CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CDCA3
    DNA2.0 Custom Variant and Variant Library Synthesis for CDCA3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607749    OMIM disorders: --

    1 disease for CDCA3:    
    About MalaCards
    clonorchiasis

    1 disease from the University of Copenhagen DISEASES database for CDCA3:
    Clonorchiasis

    Find genes that share disorders with CDCA3           About GenesLikeMe

    Genetic Association Database (GAD): CDCA3
    Human Genome Epidemiology (HuGE) Navigator: CDCA3 (1 document)

    Export disorders for CDCA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDCA3 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with CDCA3)
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    1. Drug target discovery by gene expression analysis: cell cycle genes. (PubMed id 12188893)1, 2, 3 Walker M.G. (Curr. Cancer Drug Targets 2001)
    2. Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. (PubMed id 9074930)1, 2, 3 Ansari-Lari M.A.... Gibbs R.A. (Genome Res. 1997)
    3. Identification of type 2 diabetes-associated combination of SNPs using support vector machine. (PubMed id 20416077)1, 4 Ban H.J....Park K.J. (BMC Genet. 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. HoxB3 promotes prostate cancer cell progression by transactivating CDCA3. (PubMed id 23219899)1 Chen J....Niu Y. (Cancer Lett. 2013)
    6. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest. (PubMed id 22839099)1 Uchida F....Bukawa H. (BMC Cancer 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83461 HGNC: 14624 AceView: CDCA3 Ensembl:ENSG00000111665 euGenes: HUgn83461
    ECgene: CDCA3 H-InvDB: CDCA3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDCA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDCA3 gene:
    Search GeneIP for patents involving CDCA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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