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CDCA2 Gene

protein-coding   GIFtS: 51
GCID: GC08P025316

Cell Division Cycle Associated 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cell Division Cycle Associated 21 2
Recruits PP1 Onto Mitotic Chromatin At Anaphase Protein2 3
Repo-Man2 3
Cell Division Cycle-Associated Protein 22
Protein Phosphatase 1 [Gamma] (PPP1R3A) Binding Protein Repo-Man2

External Ids:    HGNC: 146231   Entrez Gene: 1573132   Ensembl: ENSG000001846617   UniProtKB: Q69YH53   

Export aliases for CDCA2 gene to outside databases

Previous GC identifers: GC08U990159 GC08P025137 GC08P025338 GC08P025372 GC08P023861


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CDCA2 Gene:
CDCA2 (cell division cycle associated 2) is a protein-coding gene. Diseases associated with CDCA2 include dermatophytosis, and fainting.

UniProtKB/Swiss-Prot: CDCA2_HUMAN, Q69YH5
Function: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain
their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit
(PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with
chromatin targets a pool of PPP1CC to dephosphorylate substrates




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDCA2 gene promoter:
         TBP   GR   Sp1   AP-1   ATF-2   GR-beta   CREB   deltaCREB   GR-alpha   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CDCA2 promoter sequence
   Search Chromatin IP Primers for CDCA2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDCA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.2   Ensembl cytogenetic band:  8p21.2   HGNC cytogenetic band: 8p21.2

CDCA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDCA2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P025316:  view genomic region     (about GC identifiers)

Start:
25,316,513 bp from pter      End:
25,365,436 bp from pter
Size:
48,924 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CDCA2_HUMAN, Q69YH5 (See protein sequence)
Recommended Name: Cell division cycle-associated protein 2  
Size: 1023 amino acids; 112676 Da
Subunit: Interacts with PPP1CC
Sequence caution: Sequence=AAH36214.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC05374.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAH10577.1;
Type=Erroneous translation; Note=Wrong choice of CDS;
Secondary accessions: Q3SX74 Q4G0W0 Q5RKN0 Q69YI4 Q6P464 Q8N7C1
Alternative splicing: 2 isoforms:  Q69YH5-1   Q69YH5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDCA2: NX_Q69YH5

Explore proteomics data for CDCA2 at MOPED

Post-translational modifications: 

  • Phosphorylated by CDK1. May regulate its subcellular location1
  • Ubiquitination2 at Lys323
  • Modification sites at PhosphoSitePlus

  • See CDCA2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689775.2  
    ENSEMBL proteins: 
     ENSP00000328228   ENSP00000370040  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026149 Cdca2

    Graphical View of Domain Structure for InterPro Entry Q69YH5

    ProtoNet protein and cluster: Q69YH5


    CDCA2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CDCA2_HUMAN, Q69YH5
    Function: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain
    their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit
    (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with
    chromatin targets a pool of PPP1CC to dephosphorylate substrates

    Phenotypes:
         1 GenomeRNAi human phenotype for CDCA2:

     Upregulation of Wnt/beta-caten 

    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDCA2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDCA2

    miRNA
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    miRTarBase miRNAs that target CDCA2:
    hsa-mir-18a-3p (MIRT040857), hsa-mir-193b-3p (MIRT016459)

    Block miRNA regulation of human, mouse, rat CDCA2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CDCA2
    SwitchGear 3'UTR luciferase reporter plasmidCDCA2 3' UTR sequence
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    GenScript: all cDNA clones in your preferred vector: CDCA2 (NM_152562)
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CDCA2_HUMAN, Q69YH5: Nucleus. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and
    G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane
    breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it
    accumulates on chromatin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    CDCA2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CDCA2
    Interactions:

        Search GeneGlobe Interaction Network for CDCA2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for CDCA2 (Q69YH52, 3 ENSP000003282284) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MBD4O952432, 3, ENSP000002499104MINT-8262891 I2D: score=2 STRING: ENSP00000249910
    CDK1P064933I2D: score=1 
    RB1CC1Q8TDY23I2D: score=1 
    JMJD6ENSP000003940854STRING: ENSP00000394085
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--

    CDCA2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDCA2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CDCA2 gene: 
    NM_152562.2  

    Unigene Cluster for CDCA2:

    Cell division cycle associated 2
    Hs.33366  [show with all ESTs]
    Unigene Representative Sequence: NM_152562
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000330560(uc003xep.1 uc011lae.1 uc003xeq.1 uc003xer.1)
    ENST00000518225 ENST00000380665 ENST00000523454 ENST00000521098
    miRNA
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    Block miRNA regulation of human, mouse, rat CDCA2 using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidCDCA2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CDCA2
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CDCA2 (NM_152562)
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    Primer
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      QuantiFast Probe-based Assays in human, mouse, rat CDCA2

    Additional mRNA sequence: 

    AK092164.1 AK098670.1 AK292505.1 AK299278.1 AL833396.1 AL833627.1 BC015691.2 BC036214.1 
    BC063651.1 BC085609.1 BC104450.1 BC104451.1 BX649008.1 

    6 DOTS entries:

    DT.414350  DT.100747109  DT.101981664  DT.121486990  DT.100734777  DT.100747110 

    Selected AceView cDNA sequences (see all 106):

    CF528734 NM_152562 AL833396 AA770066 AA706962 AW294271 AA706943 AA815224 
    AA780179 AL833627 AA278504 CK724907 BF516303 AA682508 AA554918 AA330145 
    AA682656 AA279057 AI022757 BG772002 BC015691 BI870448 AK098670 BQ677034 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CDCA2 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ·
    SP1:                                                                                                                                                            
    SP2:                                                                                            -                                                               
    SP3:                                -                                                                                                                           
    SP4:                                                                                            -                                                               
    SP5:                                                                                                                                                            

    ExUns: 15c ^ 16
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for CDCA2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDCA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTATTCTG
    CDCA2 Expression
    About this image


    CDCA2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Mesencephalic Ventricular Zone
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
    CDCA2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDCA2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.33366

    UniProtKB/Swiss-Prot: CDCA2_HUMAN, Q69YH5
    Tissue specificity: Ubiquitously expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDCA2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDCA2 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdca21 , 5 cell division cycle associated 21, 5 68.81(n)1
    54.93(a)1
      14 (34.66 cM)5
    1089121  NM_001110162.11  NP_001103632.11 
     676763315 
    chicken
    (Gallus gallus)
    Aves CDCA26
    cell division cycle associated 2
    32(a)
    1 ↔ 1
    22(805747-813900)
    lizard
    (Anolis carolinensis)
    Reptilia CDCA26
    cell division cycle associated 2
    24(a)
    1 ↔ 1
    GL343422.1(536942-678232)
    zebrafish
    (Danio rerio)
    Actinopterygii CDCA26
    cell division cycle associated 2
    22(a)
    1 ↔ 1
    5(16181199-16204516) ENSDARG00000068759


    ENSEMBL Gene Tree for CDCA2 (if available)
    TreeFam Gene Tree for CDCA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDCA2 (see all 1113)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1158758641,2
    C,F--25317987(+) AGATAC/TTTTTA 2 T I mis13Minor allele frequency- T:0.02WA NA EU 5991
    rs115591341,2
    H--25317996(+) TAAATC/TACCTT 2 S L mis1 ese34Minor allele frequency- T:0.00NS EA 406
    rs1160864381,2
    C,F--25318021(+) GTAACC/G/TGTAGA 3 T syn11WA 216
    rs1166325861,2
    C,F--25318022(+) TAACCG/ATAGAG 2 /I /V mis11Minor allele frequency- A:0.01WA 216
    rs1830745621,2
    --25318157(+) GTACTG/TTCATA 1 -- int10--------
    rs786971641,2
    F--25318184(+) TGCCTA/GCTCTG 1 -- int11Minor allele frequency- G:0.04WA 118
    rs1481468791,2
    --25318185(+) GCCTAC/GTCTGC 1 -- int10--------
    rs1419989081,2
    --25318187(+) CTACTC/TTGCAA 1 -- int10--------
    rs170537431,2
    C,F,H--25318253(+) GGATCA/GCGGAA 1 -- int122Minor allele frequency- G:0.27NA NS EA CSA WA 2294
    rs736773251,2
    C,F--25318254(+) GATCAC/GGGAAT 1 -- int12Minor allele frequency- G:0.09WA 120

    HapMap Linkage Disequilibrium report for CDCA2 (25316513 - 25365436 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CDCA2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2736778CNV Deletion23290073
    esv999925CNV Deletion20482838
    esv1305754CNV Deletion17803354
    esv2736777CNV Deletion23290073
    esv2307416CNV Deletion18987734
    nsv396689CNV Loss16902084
    nsv819420CNV Loss19587683
    nsv890689CNV Gain21882294
    essv1351CNV CNV17122850
    esv259811OTHER Complex20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CDCA2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for CDCA2:    
    About MalaCards
    dermatophytosis    fainting    folliculitis    squamous cell carcinoma
    cerebritis

    1 disease from the University of Copenhagen DISEASES database for CDCA2:
    Dermatophytosis

    CDCA2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CDCA2
    Human Genome Epidemiology (HuGE) Navigator: CDCA2 (1 document)

    Export disorders for CDCA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDCA2 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with CDCA2)
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    1. Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability. (PubMed id 16492807)1, 2, 3 Trinkle-Mulcahy L....Lamond A.I. (J. Cell Biol. 2006)
    2. Drug target discovery by gene expression analysis: cell cycle genes. (PubMed id 12188893)1, 2, 3 Walker M.G. (Curr. Cancer Drug Targets 2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. (PubMed id 16998479)1, 2 Vagnarelli P.... Earnshaw W.C. (Nat. Cell Biol. 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man. (PubMed id 23746640)1 Qian J....Bollen M. (Curr. Biol. 2013)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis. (PubMed id 23418564)1 Uchida F....Tanzawa H. (PLoS ONE 2013)
    9. Quantitative fragmentome mapping reveals novel, domain-specific partners for the modular protein RepoMan (recruits PP1 onto mitotic chromatin at anaphase). (PubMed id 23362328)1 PrAcvost M....Trinkle-Mulcahy L. (amp 2013)
    10. Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. (PubMed id 22801782)1 Wurzenberger C....Gerlich D.W. (J. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 157313 HGNC: 14623 AceView: CDCA2 Ensembl:ENSG00000184661 euGenes: HUgn157313
    ECgene: CDCA2 H-InvDB: CDCA2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDCA2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDCA2 gene:
    Search GeneIP for patents involving CDCA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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