Aliases for CDC7 Gene
External Ids for CDC7 Gene
Previous HGNC Symbols for CDC7 Gene
Previous GeneCards Identifiers for CDC7 Gene
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]
GeneCards Summary for CDC7 Gene
CDC7 (Cell Division Cycle 7) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic. GO annotations related to this gene include protein serine/threonine kinase activity and kinase activity.
UniProtKB/Swiss-Prot for CDC7 Gene
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.