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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDC42SE1 Gene

protein-coding   GIFtS: 46
GCID: GC01M151023

CDC42 Small Effector 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CDC42 Small Effector 11 2     SCIP12
Small Effector Of CDC42 Protein 12 3     CDC42 Small Effector Protein 12
SPEC12 3     Signaling Molecule SPEC1 Beta2
CDC42-Binding Protein SCIP12 3     Small Protein Effector 1 Of Cdc422
1300002M12Rik2     

External Ids:    HGNC: 177191   Entrez Gene: 568822   Ensembl: ENSG000001976227   UniProtKB: Q9NRR83   

Export aliases for CDC42SE1 gene to outside databases

Previous GC identifers: GC00U916969 GC01M147837 GC01M149290 GC01M122400


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CDC42SE1 Gene: 
CDC42SE1 (CDC42 small effector 1) is a protein-coding gene. Diseases associated with CDC42SE1 include scarlet fever, and schistosomiasis, and among its related super-pathways are G-protein signaling RAC1 in cellular process. GO annotations related to this gene include GTPase inhibitor activity. An important paralog of this gene is CDC42SE2.

UniProtKB/Swiss-Prot: C42S1_HUMAN, Q9NRR8
Function: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing
actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in
CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in
phagocytosis in macrophages




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDC42SE1 gene promoter:
         E2F-4   E2F-3a   Elk-1   E2F-5   HSF1 (long)   E2F-2   E2F   E2F-1   POU2F1a   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDC42SE1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDC42SE1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC42SE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.1

CDC42SE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDC42SE1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M151023:  view genomic region     (about GC identifiers)

Start:
151,023,447 bp from pter      End:
151,042,801 bp from pter
Size:
19,355 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: C42S1_HUMAN, Q9NRR8 (See protein sequence)
Recommended Name: CDC42 small effector protein 1  
Size: 79 amino acids; 8925 Da
Subunit: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA
Subcellular location: Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Recruited to the activated TCR
prior actin polymerization
Secondary accessions: D3DV12 Q9HB17 Q9NQR2
Alternative splicing: 2 isoforms:  Q9NRR8-1   Q9NRR8-2   

Explore the universe of human proteins at neXtProt for CDC42SE1: NX_Q9NRR8

Explore proteomics data for CDC42SE1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRR8

  • CDC42SE1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CDC42SE1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001033796.1  NP_064624.1  

    ENSEMBL proteins: 
     ENSP00000475845   ENSP00000445647   ENSP00000349773  

    Human Recombinant Protein Products for CDC42SE1: 
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    Novus Biologicals CDC42SE1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CDC42SE1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IDA--
    GO:0005856cytoskeleton IEA--
    GO:0005886plasma membrane IEA--

    CDC42SE1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000095 PAK_box_Rho-bd

    Graphical View of Domain Structure for InterPro Entry Q9NRR8

    ProtoNet protein and cluster: Q9NRR8

    UniProtKB/Swiss-Prot: C42S1_HUMAN, Q9NRR8
    Domain: The CRIB domain mediates interaction with CDC42
    Similarity: Belongs to the CDC42SE/SPEC family
    Similarity: Contains 1 CRIB domain


    CDC42SE1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: C42S1_HUMAN, Q9NRR8
    Function: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing
    actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in
    CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in
    phagocytosis in macrophages

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005095GTPase inhibitor activity TAS10816584
         
    CDC42SE1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CDC42SE1:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CDC42SE1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDC42SE1 
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    miRNA
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    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate CDC42SE1 (see all 59):
    hsa-miR-1321 hsa-let-7d hsa-miR-29a hsa-miR-371-5p hsa-miR-766 hsa-miR-877* hsa-miR-1273d hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidCDC42SE1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC42SE1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CDC42SE1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cytoskeleton remodeling CDC42 in cellular processes
    Cytoskeleton remodeling CDC42 in cellular processes0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for CDC42SE1
        Cytoskeleton remodeling CDC42 in cellular processes


    1 GeneGo (Thomson Reuters) Pathway for CDC42SE1
        Cytoskeleton remodeling CDC42 in cellular processes



    CDC42SE1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDC42SE1

    3 Interacting proteins for CDC42SE1 (Q9NRR83) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC42P609533I2D: score=4 
    RAC1P630003I2D: score=2 
    SNCAP378403I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006909phagocytosis IEA--
    GO:0007165signal transduction TAS10816584
    GO:0008360regulation of cell shape IEA--

    CDC42SE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDC42SE1 (C42S1)

    1 HMDB Compound for CDC42SE1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about CDC42SE1 / C42S1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CDC42SE1 gene (2 alternative transcripts): 
    NM_001038707.1  NM_020239.3  

    Unigene Cluster for CDC42SE1:

    CDC42 small effector 1
    Hs.22065  [show with all ESTs]
    Unigene Representative Sequence: NM_001038707
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000439374 ENST00000483763 ENST00000492796 ENST00000470278 ENST00000491825
    ENST00000540998(uc001ewo.3 uc001ewp.3) ENST00000357235
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDC42SE1
    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate CDC42SE1 (see all 59):
    hsa-miR-1321 hsa-let-7d hsa-miR-29a hsa-miR-371-5p hsa-miR-766 hsa-miR-877* hsa-miR-1273d hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidCDC42SE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CDC42SE1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDC42SE1
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    OriGene clones in human, mouse for CDC42SE1 (see all 13)
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    Sirion Biotech Customized lentivirus for stable overexpression of CDC42SE1 
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    Primer
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    OriGene qPCR primer pairs and template standards for CDC42SE1
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDC42SE1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDC42SE1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC42SE1

    Additional mRNA sequence: 

    AF187845.2 AF286041.1 AF286592.1 BC012796.2 BC041604.1 

    18 DOTS entries:

    DT.91757184  DT.415569  DT.97807183  DT.100818452  DT.97786331  DT.91757174  DT.95091232  DT.100818449 
    DT.86851661  DT.121380245  DT.206970  DT.121380198  DT.95301026  DT.121380200  DT.91757183  DT.92334622 
    DT.95120706  DT.95201978 

    24/272 AceView cDNA sequences (see all 272):

    CB306999 AA411456 AA411584 BF512176 AV709218 AI371485 AA243027 AA301989 
    AF286041 BQ574978 CA306594 BX342479 CA312500 AA236502 AI582786 BM976123 
    BM069530 AA234381 BC012796 AI277710 AI479639 D12149 CR605469 AI245429 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDC42SE1 expression in normal human tissues (normalized intensities)      CDC42SE1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTTTCTGC
    CDC42SE1 Expression
    About this image


    CDC42SE1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Bone marrow-derived hematopoietic stem cells
             neutrophils   
     
     Uterus (Reproductive System)
             endometrial endothelial cell   

    See CDC42SE1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDC42SE1

    SOURCE GeneReport for Unigene cluster: Hs.22065

    UniProtKB/Swiss-Prot: C42S1_HUMAN, Q9NRR8
    Tissue specificity: Widely expressed. Expressed at higher level in T-lymphocytes, dendritic and whole blood cells

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC42SE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CDC42SE1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdc42se11 , 5 CDC42 small effector 11, 5 91.56(n)1
    98.73(a)1
      3 (40.74 cM)5
    579121  NM_001038708.21  NP_001033797.11 
     952287325 
    chicken
    (Gallus gallus)
    Aves CDC42SE11 CDC42 small effector 1 76.07(n)
    84.62(a)
      100857323  XM_003642684.1  XP_003642732.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDC42SE16
    Uncharacterized protein
    82(a)
    1 ↔ 1
    AAWZ02040816(552-668)
    zebrafish
    (Danio rerio)
    Actinopterygii wufa55c042 wufa55c04 76.71(n)   337314  AY423037.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Spec26
    Spec2
    33(a)
    1 → many
    3R(1442368-1449803)


    ENSEMBL Gene Tree for CDC42SE1 (if available)
    TreeFam Gene Tree for CDC42SE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDC42SE1 gene
    CDC42SE22  
    1 SIMAP similar gene for CDC42SE1 using alignment to 1 protein entry:     C42S1_HUMAN:
    CDC42SE2

    CDC42SE1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/100 SNPs in CDC42SE1 are shown (see all 100)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs801024961,2
    F--151024516(+) GGCTCG/AGGCTT 2 -- ut311Minor allele frequency- A:0.01WA 118
    rs1127925741,2
    C,F--151024529(+) GATGAA/C/GTAAGA 4 -- ut311CSA 1
    rs741250591,2
    C,F--151024535(+) TAAGAT/CGATGA 2 -- ut313Minor allele frequency- C:0.09WA CSA 122
    rs1124631021,2
    F--151024654(+) AGAGAC/TATTTT 2 -- ut311Minor allele frequency- T:0.50CSA 2
    rs108884021,2
    C,F,H--151024688(+) CAGGGG/TTGCTG 2 -- ut31 ese313Minor allele frequency- T:0.05NS NA WA CSA 349
    rs1128175431,2
    C--151024792(+) TGTTCTAGA/-  
            
    TAGAG
    2 -- ut311Minor allele frequency- -:0.50CSA 2
    rs1862317891,2
    --151024885(+) CTCAAC/TGATCA 2 -- ut310--------
    rs121358751,2
    C,H--151024942(+) GGTTTC/TTTTCC 2 -- ut316Minor allele frequency- T:0.00NS EA NA 416
    rs1395957531,2
    C--151024959(+) CTCTTC/TCTCCT 2 -- ut310--------
    rs1906204901,2
    --151025175(+) AAAAGC/GAAAGT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for CDC42SE1 (151023447 - 151042801 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CDC42SE1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv522840CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CDC42SE1
    DNA2.0 Custom Variant and Variant Library Synthesis for CDC42SE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for CDC42SE1:    About MalaCards
    scarlet fever    schistosomiasis

    1 disease from the University of Copenhagen DISEASES database for CDC42SE1:
    Scarlet fever

    CDC42SE1 for disorders           About GeneDecksing


    Export disorders for CDC42SE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDC42SE1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with CDC42SE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SPECs, small binding proteins for Cdc42. (PubMed id 10816584)1, 2, 3 Pirone D.M.... Burbelo P.D. (2000)
    2. The role of SPECs, small Cdc42-binding proteins, in F-actin accumulation at the immunological synapse. (PubMed id 15840583)1, 2 Ching K.H.... Burbelo P.D. (2005)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    4. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PubMed id 21282530)1 Vandamme J.... Angrand P.O. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. (PubMed id 18541383)1 Schnack C....Gillardon F. (2008)
    10. Biochemical characterization of distinct regions of SPEC molecules and their role in phagocytosis. (PubMed id 17045588)2 Ching K.H.... Burbelo P.D. (2007)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56882 HGNC: 17719 AceView: CDC42SE1 Ensembl:ENSG00000197622 euGenes: HUgn56882
    ECgene: CDC42SE1 H-InvDB: CDC42SE1

    (According to HUGE)
    About This Section
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for CDC42SE1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for CDC42SE1 gene:
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