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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CDC42EP3 Gene

protein-coding GIFtS: 56
GCID: GC02M037782

CDC42 effector protein (Rho GTPase binding) 3

Explore 3 diseases affiliated with
CDC42EP3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CDC42 Effector Protein (Rho GTPase Binding) 3¹ ²		MSE55-Related Cdc42-Binding Protein² ³
BORG2¹ ² ³ ⁵		Cdc42 Effector Protein 3²
CEP3¹ ² ³ ⁵		CRIB-Containing BORG2 Protein²
UB1¹ ²		MSE55-Related Protein²
Binder Of Rho GTPases 2² ³

External Ids:	HGNC: 16943¹	Entrez Gene: 10602²	Ensembl: ENSG00000163171⁷	OMIM: 606133⁵	UniProtKB: Q9UKI2³

Export aliases for CDC42EP3 gene to outside databases

Previous GC identifers: GC02M037836 GC02M038019 GC02M037845 GC02M037610

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CDC42EP3:

This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB

(Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The

encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia

formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript

variants. (provided by RefSeq, Jul 2012)

UniProtKB/Swiss-Prot: BORG2_HUMAN, Q9UKI2

Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin

filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts

Gene Wiki entry for CDC42EP3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CDC42EP3 gene promoter:
Pax-5 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) Nkx2-5 POU3F2 NF-kappaB NF-kappaB2 SEF-1 (1) NF-kappaB1 RSRFC4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CDC42EP3 promoter sequence

Search SABiosciences Chromatin IP Primers for CDC42EP3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC42EP3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p22.2 HGNC cytogenetic band: 2p21

CDC42EP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDC42EP3 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M037782: view genomic region (about GC identifiers)

Start:	37,869,032 bp from pter	End:	37,965,611 bp from pter
Size:	96,580 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BORG2_HUMAN, Q9UKI2 (See protein sequence)

Recommended Name: Cdc42 effector protein 3

Size: 254 amino acids; 27678 Da

Subunit: Interacts with RHOQ and CDC42, in a GTP-dependent manner, and with SEPT7

Subcellular location: Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton

Secondary accessions: B2R8S0 O95353 Q9UQJ0

Explore the universe of human proteins at neXtProt for CDC42EP3: NX_Q9UKI2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UKI2

CDC42EP3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001257365.1 NP_001257366.1 NP_001257367.1 NP_006440.2

ENSEMBL proteins:

ENSP00000295324 ENSP00000403298 ENSP00000398062 ENSP00000409147

Human Recombinant Protein Products for CDC42EP3:

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	Uscn Proteins for CDC42EP3

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0012505	endomembrane system	IEA	--
GO:0015629	actin cytoskeleton	IDA	--
GO:0016020	membrane	IEA	--

CDC42EP3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CDC42EP3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CDC42EP3 for domains About GeneDecksing

1 InterPro domain/family:

IPR000095 PAK_box_Rho-bd

Graphical View of Domain Structure for InterPro Entry Q9UKI2

ProtoNet protein and cluster: Q9UKI2

UniProtKB/Swiss-Prot: BORG2_HUMAN, Q9UKI2

Similarity: Belongs to the BORG/CEP family

Similarity: Contains 1 CRIB domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: BORG2_HUMAN, Q9UKI2

Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin

filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0005519	cytoskeletal regulatory protein binding	TAS	11035016

CDC42EP3 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for CDC42EP3:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CDC42EP3

miRNA Products:		OriGene 3'-UTR Clone: CDC42EP3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDC42EP3
		8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate CDC42EP3 (see all 39):
		hsa-miR-411* hsa-miR-142-5p hsa-miR-345 hsa-miR-379* hsa-miR-429 hsa-miR-605 hsa-miR-200a hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: CDC42EP3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDC42EP3 (see all 7) OriGene shRNA RFP: CDC42EP3 OriGene siRNA: CDC42EP3
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC42EP3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

G-protein signaling_RAC1 in cellular process

Cytoskeleton remodeling CDC42 in cellular processes

0.37

Cytoskeleton remodeling_CDC42 in cellular processes

0.37

Actin Nucleation by ARP-WASP Complex

RhoA Pathway

0.35

CDC42 Pathway

0.34

Rho Family GTPases

Rho Family GTPases

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for CDC42EP3

Cytoskeleton remodeling CDC42 in cellular processes

3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDC42EP3

	RhoA Pathway
	CDC42 Pathway
	Rho Family GTPases

1 GeneGo (Thomson Reuters) Pathway for CDC42EP3

Cytoskeleton remodeling CDC42 in cellular processes

CDC42EP3 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CDC42EP3

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/9 Interacting proteins for CDC42EP3 (Q9UKI2^{2, 3} ENSP00000295324⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UMPS	P11172²^,³, ENSP00000232607⁴	MINT-63458 I2D: score=5 STRING: ENSP00000232607
SEPT6	Q14141³, ENSP00000341524⁴	I2D: score=1 STRING: ENSP00000341524
SEPT7	Q16181³, ENSP00000381992⁴	I2D: score=1 STRING: ENSP00000381992
CDC42	P60953³, ENSP00000314458⁴	I2D: score=6 STRING: ENSP00000314458
RHOQ	P17081³, ENSP00000238738⁴	I2D: score=4 STRING: ENSP00000238738

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	TAS	11035016
GO:0008360	regulation of cell shape	IEA	--

CDC42EP3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CDC42EP3

1 HMDB Compound for CDC42EP3 About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about CDC42EP3 / BORG2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CDC42EP3 gene (4 alternative transcripts):

NM_001270436.1 NM_001270437.1 NM_001270438.1 NM_006449.4

Unigene Cluster for CDC42EP3:

CDC42 effector protein (Rho GTPase binding) 3

Hs.369574 [show with all ESTs]

Unigene Representative Sequence: NM_006449

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000295324(uc002rqi.1) ENST00000457889 ENST00000453555 ENST00000422687

ENST00000494083

miRNA Products:		OriGene 3'-UTR Clone: CDC42EP3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDC42EP3
		8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate CDC42EP3 (see all 39):
		hsa-miR-411* hsa-miR-142-5p hsa-miR-345 hsa-miR-379* hsa-miR-429 hsa-miR-605 hsa-miR-200a hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: CDC42EP3 3' UTR sequence

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC42EP3

Additional cDNA sequence:

AF094521.1 AF104857.1 AF164118.1 AK055915.1 AK128735.1 AK313483.1 AL136842.1 BC019270.1

BT007190.1

12 DOTS entries:

DT.113817 DT.70102907 DT.100808730 DT.95098564 DT.100728249 DT.100803234 DT.100802916 DT.100837203

DT.121015207 DT.99993163 DT.91769573 DT.99976436

24/370 AceView cDNA sequences (see all 370):

CB240788 AI401609 AI784553 BI915037 BE385516 AA213816 AW731923 BQ435221

AI096810 CB158947 BX643017 AW297492 BI793294 BC019270 AI868953 CB528603

AA127216 C04148 AI204095 BI765476 BM981107 AI766892 AI203298 AI143973

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CDC42EP3 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	·	3c
SP1:					-		-
SP2:							-
SP3:

ECgene alternative splicing isoforms for CDC42EP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CDC42EP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGTAAGAC

About this image

CDC42EP3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Metanephric Mesenchyme

Metanephric Mesenchyme Cells

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

Posterior foregut-like cells (A scalable, suspensi...)

See CDC42EP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDC42EP3

SOURCE GeneReport for Unigene cluster: Hs.369574

UniProtKB/Swiss-Prot: BORG2_HUMAN, Q9UKI2

Tissue specificity: Highly expressed in the heart and weakly in the brain

SABiosciences Expression via Pathway-Focused PCR Arrays including CDC42EP3:

Cytoskeleton Regulators in human mouse rat

Leukemia in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC42EP3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CDC42EP3 gene from 4/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CDC42EP3¹	CDC42 effector protein (Rho GTPase binding) 3	73.17(n) 78.09(a)		428577 XM_426134.3 XP_426134.1
lizard (Anolis carolinensis)	Reptilia	CDC42EP3⁶	--	74(a)	1 ↔ 1	1(232199318-232200088)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.12221²	Transcribed sequence with moderate similarity to protein more	76.92(n)		BX707700.1
zebrafish (Danio rerio)	Actinopterygii	wufc21b02²	wufc21b02	77.5(n)		324174 57051513

ENSEMBL Gene Tree for CDC42EP3 (if available)
TreeFam Gene Tree for CDC42EP3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CDC42EP3 gene

CDC42EP5² CDC42EP2² CDC42EP4² CDC42EP1²

2 SIMAP similar genes for CDC42EP3 using alignment to 4 protein entries: BORG2_HUMAN (see all proteins):

CDC42EP1 CDC42EP2

CDC42EP3 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for CDC42EP3
PGOHUM00000234638

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs17021175^1,2	C,F,H	--	37868687(+)	`CCACAA/CAACTG`	4	--	ds500¹		8		NA NS EA WA	680
rs147543083^1,2		--	37868726(+)	`AAGCTC/TTTTTT`	4	--	ds500¹		0	--	--	--	--
rs186669736^1,2		--	37868768(+)	`GTGCAA/TATTTT`	4	--	ds500¹		0	--	--	--	--
rs191169039^1,2		--	37868769(+)	`TGCATA/GTTTTG`	4	--	ds500¹		0	--	--	--	--
rs184767140^1,2		--	37868830(+)	`ACTCAC/GCTTTG`	4	--	ds500¹		0	--	--	--	--
rs190535537^1,2		--	37868905(+)	`CTGCAC/TGATGG`	4	--	ds500¹		0	--	--	--	--
rs3832104^1,2	C	--	37869040(-)	`AAAAA-/ATCCGT`	4	--	ut3¹		1		CSA	2
rs74619361^1,2		--	37869040(+)	`ACGGAT/ATTTTT`	4	--	ut3¹		1		NA	2
rs182303452^1,2		--	37869216(+)	`TGAAAA/GATATT`	4	--	ut3¹		0	--	--	--	--
rs139401099^1,2		--	37869293(+)	`AATAGG/TGCACC`	4	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CDC42EP3 (37869032 - 37965611 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CDC42EP3
1 CNV: 3352

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDC42EP3

DNA2.0 Custom Variant and Variant Library Synthesis for CDC42EP3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CDC42EP3 for disorders           About GeneDecksing

OMIM gene information: 606133    OMIM disorders: --

3 diseases for CDC42EP3:    About MalaCards

excessive tearing alzheimer's disease pneumonia

Export disorders for CDC42EP3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CDC42EP3 gene, integrated from 9 sources (see all 31):
(articles sorted by number of sources associating them with CDC42EP3)

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A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. (PubMed id 11035016)^{1, 2, 3, 9} Hirsch D.S....Burbelo P.D. (2001)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
Borg proteins control septin organization and are negatively regulated by Cdc42. (PubMed id 11584266)^{1, 2} Joberty G.... Macara I.G. (2001)
The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. (PubMed id 10490598)^{1, 2} Joberty G.... Macara I.G. (1999)
Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. (PubMed id 9535835)^{1, 3} Alberts A.S....Treisman R. (1998)
Human fertility protein PUMILIO2 interacts in vitro with testis mRNA encoding Cdc42 effector 3 (CEP3). (PubMed id 17173092)^{1, 9} Spik A....Jaruzelska J. (2006)
Identification and characterization of genes related t o the development of breast muscles in Pekin duck. (PubMed id 22451153)¹ Xu T....Hou S. (2012)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10602	HGNC: 16943	AceView: CDC42EP3	Ensembl:ENSG00000163171	euGenes: HUgn10602
ECgene: CDC42EP3	H-InvDB: CDC42EP3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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Name	Description
PharmGKB entry for CDC42EP3	Pharmacogenomics, SNPs, Pathways

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CDC42EP3 Gene

CDC42 effector protein (Rho GTPase binding) 3

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CDC42 effector protein (Rho GTPase binding) 3

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