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CDC42EP2 Gene

protein-coding   GIFtS: 52
GCID: GC11P065082

CDC42 Effector Protein (Rho GTPase Binding) 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CDC42 Effector Protein (Rho GTPase Binding) 21 2
BORG12 3 5
CEP22 3 5
CRIB-Containing BOGR1 Protein1 2
Binder Of Rho GTPases 12 3
Cdc42 Effector Protein 22

External Ids:    HGNC: 162631   Entrez Gene: 104352   Ensembl: ENSG000001497987   OMIM: 6061325   UniProtKB: O146133   

Export aliases for CDC42EP2 gene to outside databases

Previous GC identifers: GC11P067598 GC11P066764 GC11P065332 GC11P064857 GC11P064838 GC11P061409


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CDC42EP2 Gene:
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with
the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42
effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and
negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this
protein in actin filament assembly and cell shape control. (provided by RefSeq, Aug 2011)

GeneCards Summary for CDC42EP2 Gene:
CDC42EP2 (CDC42 effector protein (Rho GTPase binding) 2) is a protein-coding gene. GO annotations related to this gene include Rho GTPase activator activity and opioid peptide activity. An important paralog of this gene is CDC42EP3.

UniProtKB/Swiss-Prot: BORG1_HUMAN, O14613
Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce
actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a
CDC42-dependent manner

Gene Wiki entry for CDC42EP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDC42EP2 gene promoter:
         Spz1   Elk-1   p53   Sp1   IRF-1   STAT5A   PPAR-gamma1   NRF-2   FOXO4   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDC42EP2 promoter sequence
   Search Chromatin IP Primers for CDC42EP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDC42EP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

CDC42EP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDC42EP2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P065082:  view genomic region     (about GC identifiers)

Start:
65,082,289 bp from pter      End:
65,089,900 bp from pter
Size:
7,612 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BORG1_HUMAN, O14613 (See protein sequence)
Recommended Name: Cdc42 effector protein 2  
Size: 210 amino acids; 22484 Da
Subunit: Interacts with RHOQ and CDC42 in a GTP-dependent manner, and with SEPT7
Secondary accessions: B2RD85 Q9UNS0

Explore the universe of human proteins at neXtProt for CDC42EP2: NX_O14613

Explore proteomics data for CDC42EP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CDC42EP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006770.1  
    ENSEMBL proteins: 
     ENSP00000279249   ENSP00000431660   ENSP00000442534  

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    antibodies-online peptides for CDC42EP2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000095 CRIB_dom
     IPR017363 Cdc42_effector_prot_2

    Graphical View of Domain Structure for InterPro Entry O14613

    ProtoNet protein and cluster: O14613

    UniProtKB/Swiss-Prot: BORG1_HUMAN, O14613
    Domain: The CRIB domain mediates interaction with CDC42
    Similarity: Belongs to the BORG/CEP family
    Similarity: Contains 1 CRIB domain


    Find genes that share domains with CDC42EP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BORG1_HUMAN, O14613
    Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce
    actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a
    CDC42-dependent manner

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001515opioid peptide activity IEA--
    GO:0005100Rho GTPase activator activity IMP10430899
    GO:0005515protein binding IPI11584266
    GO:0017049GTP-Rho binding IPI11035016
         
    Find genes that share ontologies with CDC42EP2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CDC42EP2:
     Wnt reporter downregulated 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDC42EP2
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    hsa-miR-634 hsa-miR-137 hsa-miR-92a hsa-miR-15a hsa-miR-367 hsa-miR-25 hsa-miR-497 hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidCDC42EP2 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BORG1_HUMAN, O14613: Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    plasma membrane5
    cytosol3
    extracellular1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA10430899
    GO:0012505endomembrane system IEA--
    GO:0015630microtubule cytoskeleton IDA--
    GO:0016020membrane IDA11035016

    Find genes that share ontologies with CDC42EP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CDC42EP2 About    
    See pathways by source

    SuperPathContained pathways About
    1Actin Nucleation by ARP-WASP Complex
    CDC42 Pathway0.41
    RhoA Pathway0.35
    2ERK Signaling
    Rho Family GTPases0.61
    3G protein signaling RAC1 in cellular process
    Cytoskeleton remodeling CDC42 in cellular processes0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CDC42EP2
        RhoA Pathway
    CDC42 Pathway
    Rho Family GTPases

    1 GeneGo (Thomson Reuters) Pathway for CDC42EP2
        Cytoskeleton remodeling CDC42 in cellular processes


        Pathway & Disease-focused RT2 Profiler PCR Array including CDC42EP2: 
              Cytoskeleton Regulators in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CDC42EP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for CDC42EP2 (O146133 ENSP000002792494) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SEPT7Q161813, ENSP000003819924I2D: score=2 STRING: ENSP00000381992
    SEPT6Q141413, ENSP000003415244I2D: score=1 STRING: ENSP00000341524
    CDC42P609533, ENSP000003144584I2D: score=5 STRING: ENSP00000314458
    RHOQP170813, ENSP000002387384I2D: score=3 STRING: ENSP00000238738
    SNCAP378403, ENSP000003383454I2D: score=1 STRING: ENSP00000338345
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    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007015actin filament organization NAS11035016
    GO:0008360regulation of cell shape IDA11035016
    GO:0030036actin cytoskeleton organization IDA10430899
    GO:0030838positive regulation of actin filament polymerization IDA11035016
    GO:0031274positive regulation of pseudopodium assembly IDA11035016

    Find genes that share ontologies with CDC42EP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDC42EP2 (BORG1)

    1 HMDB Compound for CDC42EP2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CDC42EP2 gene: 
    NM_006779.3  

    Unigene Cluster for CDC42EP2:

    CDC42 effector protein (Rho GTPase binding) 2
    Hs.343380  [show with all ESTs]
    Unigene Representative Sequence: AK098292
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000279249(uc001odl.3) ENST00000533419 ENST00000544348
    miRNA
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    hsa-miR-634 hsa-miR-137 hsa-miR-92a hsa-miR-15a hsa-miR-367 hsa-miR-25 hsa-miR-497 hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidCDC42EP2 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat CDC42EP2
      QuantiFast Probe-based Assays in human, mouse, rat CDC42EP2

    Additional mRNA sequence: 

    AF001436.1 AF098290.1 AF163840.1 AK098292.1 AK315444.1 BC022337.1 BC075834.1 BT020004.1 

    5 DOTS entries:

    DT.413804  DT.100019205  DT.100692155  DT.97764715  DT.100000194 

    Selected AceView cDNA sequences (see all 352):

    AU130810 BP379233 BF508931 BX956155 AK025315 BG680695 AL702238 BM984693 
    CR609836 AW248781 CR614190 BX345865 BM750008 AW449558 CA437753 BM543270 
    CD516028 BQ447537 BX345864 F07645 AL702193 Z39767 BQ670878 BQ063736 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDC42EP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCTGCTGG
    CDC42EP2 Expression
    About this image


    CDC42EP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter
     
     Spinal Cord (Nervous System)
    CDC42EP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDC42EP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.343380

    UniProtKB/Swiss-Prot: BORG1_HUMAN, O14613
    Tissue specificity: Highly expressed in the heart. Weakly expressed in the pancreas and liver

        Pathway & Disease-focused RT2 Profiler PCR Array including CDC42EP2: 
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CDC42EP2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdc42ep21 , 5 CDC42 effector protein (Rho GTPase binding) 21, 5 85.4(n)1
    88.57(a)1
      19 (4.34 cM)5
    1042521  NM_026772.21  NP_081048.11 
     59175565 
    chicken
    (Gallus gallus)
    Aves CDC42EP21 CDC42 effector protein (Rho GTPase binding) 2 70.45(n)
    71.13(a)
      426985  XM_004950210.1  XP_004950267.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDC42EP26
    CDC42 effector protein (Rho GTPase binding) 2
    90(a)
    1 ↔ 1
    GL345117.1(1737-1937)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC537322 similar to CDC42 effector protein (Rho GTPase binding) more 74.34(n)    BC045241.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cdc42ep21 CDC42 effector protein (Rho GTPase binding) 2 60.45(n)
    66.32(a)
      541404  NM_001013531.1  NP_001013549.1 


    ENSEMBL Gene Tree for CDC42EP2 (if available)
    TreeFam Gene Tree for CDC42EP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDC42EP2 gene
    CDC42EP32  
    1 SIMAP similar gene for CDC42EP2 using alignment to 1 protein entry:     BORG1_HUMAN:
    CDC42EP3

    Find genes that share paralogs with CDC42EP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDC42EP2 (see all 228)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1844660381,2
    --65080306(+) ATCTCA/GGCTCA 1 -- us2k10--------
    rs665360701,2
    C--65080428(-) AAAAA-/ATTAGC 1 -- us2k11Minor allele frequency- A:0.00NA 2
    rs29571091,2
    A,H--65080444(+) ttttgT/Gatttt 1 -- us2k14Minor allele frequency- G:0.00NS EA 418
    rs1876029031,2
    --65080686(+) GCTCTA/GTTGCC 1 -- us2k10--------
    rs1922380471,2
    --65080712(+) TGGCGC/TGATCA 1 -- us2k10--------
    rs1468421991,2
    C--65081027(+) AGCTTA/GTCTGG 1 -- us2k10--------
    rs1479558511,2
    --65081062(+) TGCCTC/TCCCCA 1 -- us2k10--------
    rs1840286591,2
    --65081155(+) TGGCAC/TAGCTG 1 -- us2k10--------
    rs127996741,2
    C,H--65081223(+) CCACTC/TTTCTT 1 -- us2k12Minor allele frequency- T:0.01NS NA 182
    rs1418999421,2
    C--65081352(+) GCTAGA/GCACTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CDC42EP2 (65082289 - 65089900 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CDC42EP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422285CNV Deletion17116639
    nsv832190CNV Loss17160897
    nsv897714CNV Loss21882294
    dgv1175n71CNV Loss21882294
    nsv526181CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606132    OMIM disorders: --


    Find genes that share disorders with CDC42EP2           About GenesLikeMe


    Export disorders for CDC42EP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDC42EP2 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with CDC42EP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. (PubMed id 11035016)1, 2, 3 Hirsch D.S.... Burbelo P.D. (J. Biol. Chem. 2001)
    2. The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. (PubMed id 10490598)1, 2, 3 Joberty G.... Macara I.G. (Mol. Cell. Biol. 1999)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Borg proteins control septin organization and are negatively regulated by Cdc42. (PubMed id 11584266)1, 2 Joberty G.... Macara I.G. (Nat. Cell Biol. 2001)
    6. A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. (PubMed id 9253601)1, 2 Guru S.C.... Chandrasekharappa S.C. (Genome Res. 1997)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Early proliferation alteration and differential gene expression in human periodontal ligament cells subjected to cyclic tensile stress. (PubMed id 20934684)1 Wang Y....Zhao Z. (Arch. Oral Biol. 2011)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10435 HGNC: 16263 AceView: POLA2andCDC42EP2 Ensembl:ENSG00000149798 euGenes: HUgn10435
    ECgene: CDC42EP2 H-InvDB: CDC42EP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDC42EP2 Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/cdc42ep2/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDC42EP2 gene:
    Search GeneIP for patents involving CDC42EP2

    GeneCards and IP:
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