Aliases for CDC40 Gene
External Ids for CDC40 Gene
Previous GeneCards Identifiers for CDC40 Gene
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDC40 Gene
CDC40 (Cell Division Cycle 40) is a Protein Coding gene. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and RNA Polymerase II Transcription Termination. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is WDR25.
UniProtKB/Swiss-Prot for CDC40 Gene
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.