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Aliases for CDC20B Gene

Aliases for CDC20B Gene

  • Cell Division Cycle 20B 2 3
  • CDC20 Cell Division Cycle 20 Homolog B (S. Cerevisiae) 2
  • Cell Division Cycle 20 Homolog B (S. Cerevisiae) 2
  • Cell Division Cycle Protein 20 Homolog B 3
  • CDC20 Cell Division Cycle 20 Homolog B 3
  • Cell Division Cycle 20 Homolog B 3
  • CDC20-Like Protein 3
  • G6VTS76519 3

External Ids for CDC20B Gene

Summaries for CDC20B Gene

GeneCards Summary for CDC20B Gene

CDC20B (Cell Division Cycle 20B) is a Protein Coding gene. Among its related pathways are miRNA Regulation of DNA Damage Response. An important paralog of this gene is FZR1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDC20B Gene

Genomics for CDC20B Gene

Genomic Location for CDC20B Gene

Start:
55,112,971 bp from pter
End:
55,173,177 bp from pter
Size:
60,207 bases
Orientation:
Minus strand

Genomic View for CDC20B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CDC20B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDC20B Gene

Regulatory Elements for CDC20B Gene

Proteins for CDC20B Gene

  • Protein details for CDC20B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86Y33-CD20B_HUMAN
    Recommended name:
    Cell division cycle protein 20 homolog B
    Protein Accession:
    Q86Y33
    Secondary Accessions:
    • B7WNV8
    • B9EGL8
    • C9J6X8
    • C9JHE9
    • C9JKL5
    • Q86Y31
    • Q86Y32
    • Q8IUZ8
    • Q8N1S1
    • Q8NG56

    Protein attributes for CDC20B Gene

    Size:
    519 amino acids
    Molecular mass:
    57335 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB97393.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CDC20B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CDC20B Gene

Proteomics data for CDC20B Gene at MOPED

Post-translational modifications for CDC20B Gene

No Post-translational modifications

Other Protein References for CDC20B Gene

No data available for DME Specific Peptides for CDC20B Gene

Domains for CDC20B Gene

Gene Families for CDC20B Gene

HGNC:
  • WDR :WD repeat domain containing

Protein Domains for CDC20B Gene

UniProtKB/Swiss-Prot:

CD20B_HUMAN
Family:
  • Belongs to the WD repeat CDC20/Fizzy family.:
    • Q86Y33
Similarity:
  • Contains 7 WD repeats.:
    • Q86Y33
genes like me logo Genes that share domains with CDC20B: view

Function for CDC20B Gene

Gene Ontology (GO) - Molecular Function for CDC20B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CDC20B: view

Phenotypes for CDC20B Gene

GenomeRNAi human phenotypes for CDC20B:
genes like me logo Genes that share phenotypes with CDC20B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CDC20B Gene

Localization for CDC20B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CDC20B Gene COMPARTMENTS Subcellular localization image for CDC20B gene
Compartment Confidence
nucleus 2
cytoskeleton 1
cytosol 1
extracellular 1
lysosome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for CDC20B Gene

Pathways for CDC20B Gene

genes like me logo Genes that share pathways with CDC20B: view

Pathways by source for CDC20B Gene

1 BioSystems pathway for CDC20B Gene

Gene Ontology (GO) - Biological Process for CDC20B Gene

None

Transcripts for CDC20B Gene

Unigene Clusters for CDC20B Gene

Cell division cycle 20B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CDC20B Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b
SP1: - - - -
SP2: - - -
SP3: - - - -
SP4: - -
SP5: - -
SP6:

Relevant External Links for CDC20B Gene

GeneLoc Exon Structure for
CDC20B
ECgene alternative splicing isoforms for
CDC20B

Expression for CDC20B Gene

mRNA expression in normal human tissues for CDC20B Gene

mRNA differential expression in normal tissues according to GTEx for CDC20B Gene

This gene is overexpressed in Testis (30.7), Lung (9.9), and Kidney - Cortex (4.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CDC20B Gene

SOURCE GeneReport for Unigene cluster for CDC20B Gene Hs.669184

genes like me logo Genes that share expressions with CDC20B: view

Orthologs for CDC20B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CDC20B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CDC20B 36
  • 98.9 (n)
  • 97.86 (a)
CDC20B 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CDC20B 36
  • 84.67 (n)
  • 78.17 (a)
CDC20B 37
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CDC20B 36
  • 85.56 (n)
  • 80.46 (a)
CDC20B 37
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cdc20b 36
  • 78.98 (n)
  • 72.53 (a)
Cdc20b 16
Cdc20b 37
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CDC20B 37
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 13 (a)
ManyToMany
chicken
(Gallus gallus)
Aves CDC20B 36
  • 60.64 (n)
  • 53.85 (a)
CDC20B 37
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CDC20B 37
  • 40 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cdc20b 36
  • 57.14 (n)
  • 50.4 (a)
Str.16369 36
zebrafish
(Danio rerio)
Actinopterygii si:ch73-182a11.1 37
  • 25 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta fzy 37
  • 27 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea fzy-1 37
  • 17 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CDH1 37
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10505 37
  • 26 (a)
OneToMany
Species with no ortholog for CDC20B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CDC20B Gene

ENSEMBL:
Gene Tree for CDC20B (if available)
TreeFam:
Gene Tree for CDC20B (if available)

Paralogs for CDC20B Gene

Paralogs for CDC20B Gene

Selected SIMAP similar genes for CDC20B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CDC20B: view

Variants for CDC20B Gene

Sequence variations from dbSNP and Humsavar for CDC20B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs182858 -- 55,137,248(-) TGGCA(A/G)TTTCT intron-variant
rs186762 -- 55,135,248(-) tctGT(A/G)TATAT intron-variant
rs191396 -- 55,143,685(-) TATCT(G/T)GTTTT intron-variant
rs193104 -- 55,131,457(-) atttg(G/T)gtttc intron-variant
rs233625 -- 55,157,548(-) TACGT(A/G)TATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CDC20B Gene

Variant ID Type Subtype PubMed ID
nsv830301 CNV Gain 17160897
nsv4833 CNV Loss 18451855
nsv830302 CNV Gain 17160897
nsv823075 CNV Loss 20364138
nsv823077 CNV Loss 20364138

Relevant External Links for CDC20B Gene

HapMap Linkage Disequilibrium report
CDC20B

Disorders for CDC20B Gene

No disorders were found for CDC20B Gene.

No data available for UniProtKB/Swiss-Prot for CDC20B Gene

Publications for CDC20B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for CDC20B Gene

Sources for CDC20B Gene

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