CDC14B Gene
protein-coding GIFtS: 60
GCID: GC09M099252
|
|
cell division cycle 14B(Previous names: CDC14 (cell division cycle 14, S. cerevisiae) homolog B,...)
| |
Aliases
for CDC14B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cell Division Cycle 14B1 2 | | CDC14 (Cell Division Cycle 14, S. Cerevisiae) Homolog B1 | | CDC14B31 2 | | CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae)1 | | Cdc14B11 2 | | Dual Specificity Protein Phosphatase CDC14B2 | | Cdc14B21 2 | | EC 3.1.3.163 | | HCDC14B1 | | EC 3.1.3.483 | | CDC14 Cell Division Cycle 14 Homolog B2 3 | | |
Export aliases for CDC14B gene to outside databasesPrevious GC identifers: GC09M090066 GC09M090996 GC09M092709 GC09M094632 GC09M096332 GC09M098292 |
Summaries
for CDC14B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CDC14B:
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This proteinis highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cellmitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shownto interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53.Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: CC14B_HUMAN, O60729Function: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damagecheckpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of theanaphase promoting complex/cyclosome (APC/C). Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to theubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified byproline-directed kinases
Gene Wiki entry for CDC14B
|
Genomic Views
for CDC14B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDC14B gene promoter:
E2F-4 E2F-3a AhR Elk-1 AML1a E2F-2 POU6F1 (c2) Arnt E2F-1 FOXO4
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDC14B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC14B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q22.3 Ensembl cytogenetic band: 9q22.33 HGNC cytogenetic band: 9q22.3CDC14B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M099252: view genomic region
(about GC identifiers)
Start:
|
99,252,523 bp from pter |
End:
|
99,382,112 bp from pter |
Size:
|
129,590 bases |
Orientation:
|
minus strand |
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Proteins
for CDC14B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC14B_HUMAN, O60729 (See
protein sequence)Recommended Name: Dual specificity protein phosphatase CDC14B Size: 498 amino acids; 56802 Da
Subunit: Interacts with FZR1/CDH1
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Following DNA damage, translocates from thenucleolus to the nucleoplasm and interacts with FZR1/CDH1
Sequence caution: Sequence=CAI40539.1; Type=Erroneous initiation;
3 PDB 3D structures from  and Proteopedia  for CDC14B:1OHC (3D)
1OHD (3D)
1OHE (3D)
Secondary accessions: A6N5X8 A8MQ20 B1AL31 B1AL32 O43183 O60730 Q5JU08Alternative splicing: 5 isoforms: O60729-1 O60729-2 O60729-3 O60729-4 O60729-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CDC14B: NX_O60729
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60729
CDC14B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001070649.1 NP_003662.1 NP_201588.1
ENSEMBL proteins: ENSP00000417897 ENSP00000413940 ENSP00000364389 ENSP00000364388 ENSP00000364390 ENSP00000420572 ENSP00000396951 ENSP00000400480 ENSP00000265659 ENSP00000364384
Human Recombinant Protein Products for CDC14B:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CDC14B for ontologies About GeneDecksing
CDC14B Antibody Products:
Assay Products for CDC14B: |
Protein
Domains /
Families
for CDC14B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDC14B for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60729ProtoNet protein and cluster: O60729 1 Blocks protein family: IPB000340 Dual specificity protein phosphatase
UniProtKB/Swiss-Prot: CC14B_HUMAN, O60729Domain: Composed of two structurally equivalent A and B domains that adopt a dual specificity protein phosphatase (DSP)foldSimilarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily |
Function
for CDC14B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CC14B_HUMAN, O60729Function: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damagecheckpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of theanaphase promoting complex/cyclosome (APC/C). Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to theubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified byproline-directed kinasesCatalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphateCatalytic activity: A phosphoprotein + H(2)O = a protein + phosphate Enzyme Numbers (IUBMB): EC 3.1.3.161 EC 3.1.3.481
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004722 | protein serine/threonine phosphatase activity |
IDA | 18662541 | | GO:0004725 | protein tyrosine phosphatase activity |
IDA | 9367992 | | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity |
IEA | -- |
CDC14B for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CDC14B:
8 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Cdc14b):
CDC14B for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Cdc14btm1.2Pzg for CDC14B
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CDC14B (NM_003671) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDC14B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC14B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC14B |
|
Pathways & Interactions
for CDC14B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell cycle | | | 2 | PLK1 signaling events | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for CDC14B
1 
Kegg Pathway (Kegg details for CDC14B):
CDC14B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDC14B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/31 Interacting proteins for CDC14B (O607292, 3 ENSP000003643894) via UniProtKB, MINT, STRING, and/or I2D (see all 31)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
CDC14B for ontologies About GeneDecksing
|
Drugs & Compounds
for CDC14B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDC14B
3 HMDB Compounds for CDC14B About this table
Search CenterWatch for drugs/clinical trials and news about CDC14B / CC14B
|
Transcripts
for CDC14B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDC14B gene (4 alternative transcripts): NM_001077181.1 NM_003671.3 NM_033331.2 NM_033332.1 Unigene Cluster for CDC14B: CDC14 cell division cycle 14 homolog B (S. cerevisiae) Hs.40582 [show with all ESTs]Unigene Representative Sequence: NM_03333115 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000474602 ENST00000412285(uc004awi.3) ENST00000375241(uc004awj.3 uc004awk.3 uc004awl.3)
ENST00000375240 ENST00000375242 ENST00000463569 ENST00000481149 ENST00000452280
ENST00000415608 ENST00000480920 ENST00000496750 ENST00000463547 ENST00000484948
ENST00000265659 ENST00000375236
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): CDC14B (NM_003671) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDC14B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC14B |
Additional cDNA sequence: AF064104.1 AK024886.1 AK126388.1 AK225361.1 BC050013.1 EF611343.1 16 DOTS entries: DT.454283 DT.91840499 DT.100739533 DT.100017203 DT.40202717 DT.317227 DT.100812802 DT.121174362 DT.91743831 DT.91909711 DT.97790162 DT.102832313 DT.121174427 DT.75105618 DT.91813544 DT.92324051 24/173 AceView cDNA sequences (see all 173): AI339756 BI492504 AI376757 BX641741 AF064104 BM722702 AI368021 AI828647 BE645878 CF272197 T35321 AK024886 BM687919 AU119655 CA418492 CK906128 AW271614 AI200409 Z43835 AA777790 AA242742 BM740949 AW118831 BG058500
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CDC14B About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | - | | | |
ECgene alternative splicing isoforms for CDC14B
|
Expression
for CDC14B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDC14B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATTAAAAG
About this image
See CDC14B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDC14B
SOURCE GeneReport for Unigene cluster: Hs.40582
SABiosciences Expression via Pathway-Focused PCR Arrays including CDC14B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDC14B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDC14B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDC14B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC14B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC14B |
Orthologs
for CDC14B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CDC14B gene from 7/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cdc14b1 , 5 |
CDC14 cell division cycle 14 homolog B (S. cerevisiae)5
CDC14 cell division cycle 14B1 |
87.72(n)1
87.05(a)1 |
|
13 (33.26 cM)5
2182941 NM_172587.31 NP_766175.31
641925455 |
chicken
(Gallus gallus) |
Aves |
CDC14B1 |
CDC14 cell division cycle 14 homolog B (S. cerevisiae) |
70.59(n)
65.13(a) |
|
427473 XM_425045.3 XP_425045.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CDC14B6 |
-- |
66(a) |
1 ↔ 1 |
2(39928474-39949634) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.193102 |
Transcribed sequence with moderate similarity to protein more |
74.43(n) |
|
AL874877.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
cdc14b6 |
CDC14 cell division cycle 14 homolog B |
54(a) |
1 ↔ 1 |
8(1290801-1335916) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG71343 |
protein amino acid dephosphorylation protein
tyrosine/serine/threonine more |
59(a) |
|
28C4 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
cdc-146 |
Probable tyrosine-protein phosphatase cdc-14 |
15(a) |
1 → many |
II(5587606-5593410) |
ENSEMBL Gene Tree for CDC14B (if available)
TreeFam Gene Tree for CDC14B (if available) |
Paralogs
for CDC14B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDC14B gene
- CDC14A2 DUSP232
4 SIMAP similar genes for CDC14B using alignment to 5 protein entries: CC14B_HUMAN (see all proteins):CDC14C MGC26484 CDC14A DUSP23
CDC14B for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for CDC14B
PGOHUM00000250867 PGOHUM00000250932
|
Genomic Variants
for CDC14B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDC14B (99252523 - 99382112 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CDC14B
1 CNV: 6700
2 Indels: 47756 60762 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDC14B |
|
Disorders
/ Diseases
for CDC14B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CDC14B for disorders About GeneDecksing
OMIM gene information: 603505
OMIM disorders: --
2  diseases for CDC14B: About MalaCardshepatocellular carcinoma carcinoma
Export disorders for CDC14B gene to outside databases
|
Publications
for CDC14B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDC14B gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with CDC14B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. (PubMed id 9367992)1, 2, 3 Li L.... Dixon J.E. (1997)
- The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. (PubMed id 18662541)1, 2 Bassermann F....Pagano M. (2008)
- The structure of the cell cycle protein Cdc14 reveals a proline- directed protein phosphatase. (PubMed id 12853468)1, 2 Gray C.H.... Barford D. (2003)
- Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. (PubMed id 11901424)1, 2 Mailand N.... Lukas J. (2002)
- Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. (PubMed id 12134069)1, 2 Kaiser B.K.... Jackson P.K. (2002)
- The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules. (PubMed id 15899858)1, 9 Cho H.P....Wang Y. (2005)
- Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication. (PubMed id 18458157)1, 9 Wu J....Wang Y. (2008)
- Functional homology among human and fission yeast Cdc14 phosphatases. (PubMed id 15911625)1, 9 Vazquez-Novelle M.D....Sacristan M.P. (2005)
- The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. (PubMed id 10644693)1, 9 Li L....Dixon J.E. (2000)
- Phospho-regulation of KIBRA by CDK1 and CDC14 phosphat ase controls cell-cycle progression. (PubMed id 22784093)1 Ji M....Dong J. (2012)
|
External Searches for CDC14B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDC14B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDC14B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDC14B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CDC14B gene:
Search GeneIP for patents involving CDC14B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDC14B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CDC14B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDC14B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDC14B | | | OriGene Protein Over-expression Lysate for CDC14B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDC14B | | OriGene 3'-UTR Clone for CDC14B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC14B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDC14B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDC14B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC14B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDC14B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC14B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDC14B |
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| | | | Search Tocris compounds for CDC14B |
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 | | | CDC14B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC14B |
|  |  |  |  | | | | ThermoFisher Antibodies for CDC14B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC14B |
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