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Aliases for CDADC1 Gene

Aliases for CDADC1 Gene

  • Cytidine And DCMP Deaminase Domain Containing 1 2 3
  • Testis Development Protein NYD-SP15 3 4
  • Cytidine And DCMP Deaminase Domain-Containing Protein 1 3
  • Protein Kinase NYD-SP15 3
  • BA103J18.1 3
  • NYD-SP15 3

External Ids for CDADC1 Gene

Previous GeneCards Identifiers for CDADC1 Gene

  • GC13P047620
  • GC13P048720
  • GC13P049822
  • GC13P030615

Summaries for CDADC1 Gene

GeneCards Summary for CDADC1 Gene

CDADC1 (Cytidine And DCMP Deaminase Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity.

UniProtKB/Swiss-Prot for CDADC1 Gene

  • May play an important role in testicular development and spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDADC1 Gene

Genomics for CDADC1 Gene

Regulatory Elements for CDADC1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CDADC1 Gene

49,247,911 bp from pter
49,293,486 bp from pter
45,576 bases
Plus strand

Genomic View for CDADC1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CDADC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDADC1 Gene

Proteins for CDADC1 Gene

  • Protein details for CDADC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cytidine and dCMP deaminase domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q49A08
    • Q4G119
    • Q5TAW9
    • Q7Z764
    • Q9NT36

    Protein attributes for CDADC1 Gene

    514 amino acids
    Molecular mass:
    58455 Da
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CDADC1 Gene


neXtProt entry for CDADC1 Gene

Proteomics data for CDADC1 Gene at MOPED

Post-translational modifications for CDADC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CDADC1 Gene

Antibody Products

No data available for DME Specific Peptides for CDADC1 Gene

Domains for CDADC1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q9BWV3
  • Contains 2 CMP/dCMP-type deaminase domains.
  • Belongs to the cytidine and deoxycytidylate deaminase family.
genes like me logo Genes that share domains with CDADC1: view

No data available for Gene Families for CDADC1 Gene

Function for CDADC1 Gene

Molecular function for CDADC1 Gene

UniProtKB/Swiss-Prot Function:
May play an important role in testicular development and spermatogenesis.

Gene Ontology (GO) - Molecular Function for CDADC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity --
GO:0008270 zinc ion binding IEA --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with CDADC1: view
genes like me logo Genes that share phenotypes with CDADC1: view

Animal Model Products

miRNA for CDADC1 Gene

miRTarBase miRNAs that target CDADC1

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CDADC1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CDADC1 Gene

Localization for CDADC1 Gene

Subcellular locations from

Jensen Localization Image for CDADC1 Gene COMPARTMENTS Subcellular localization image for CDADC1 gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CDADC1 Gene

Pathways for CDADC1 Gene

SuperPathways for CDADC1 Gene

No Data Available

Interacting Proteins for CDADC1 Gene

Gene Ontology (GO) - Biological Process for CDADC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with CDADC1: view

No data available for Pathways by source for CDADC1 Gene

Transcripts for CDADC1 Gene

Unigene Clusters for CDADC1 Gene

Cytidine and dCMP deaminase domain containing 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CDADC1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CDADC1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14
SP1: - - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5: - - - - -
SP6: - - -
SP7: - - - - - -

Relevant External Links for CDADC1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CDADC1 Gene

mRNA expression in normal human tissues for CDADC1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CDADC1 Gene

SOURCE GeneReport for Unigene cluster for CDADC1 Gene Hs.388220

mRNA Expression by UniProt/SwissProt for CDADC1 Gene

Tissue specificity: Widely expressed. Expressed at high levels in the testis.
genes like me logo Genes that share expressions with CDADC1: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Expression partners for CDADC1 Gene

Orthologs for CDADC1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CDADC1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CDADC1 35
  • 90.73 (n)
  • 91.05 (a)
  • 88 (a)
(Canis familiaris)
Mammalia CDADC1 35
  • 91.89 (n)
  • 92.41 (a)
  • 92 (a)
(Mus musculus)
Mammalia Cdadc1 35
  • 87.87 (n)
  • 89.24 (a)
Cdadc1 16
Cdadc1 36
  • 86 (a)
(Pan troglodytes)
Mammalia CDADC1 35
  • 99.87 (n)
  • 100 (a)
  • 100 (a)
(Monodelphis domestica)
Mammalia CDADC1 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia CDADC1 36
  • 81 (a)
(Gallus gallus)
Aves CDADC1 35
  • 78.32 (n)
  • 83.16 (a)
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cdadc1 35
  • 71.07 (n)
  • 74.89 (a)
(Danio rerio)
Actinopterygii cdadc1 35
  • 60.61 (n)
  • 59.54 (a)
cdadc1 36
  • 52 (a)
Species with no ortholog for CDADC1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CDADC1 Gene

Gene Tree for CDADC1 (if available)
Gene Tree for CDADC1 (if available)

Paralogs for CDADC1 Gene

No data available for Paralogs for CDADC1 Gene

Variants for CDADC1 Gene

Sequence variations from dbSNP and Humsavar for CDADC1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs719614 -- 49,271,349(-) AGACA(C/T)GAAGA intron-variant
rs1555670 -- 49,283,185(-) atatG(A/T)TATAT intron-variant
rs1924657 -- 49,288,989(-) ACCTG(A/C)TCTCA intron-variant
rs1924658 -- 49,279,816(-) CTAAC(A/G)ACTGG intron-variant
rs1924660 -- 49,269,949(-) ATTGA(A/C)CATCA intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CDADC1 Gene

Variant ID Type Subtype PubMed ID
nsv832607 CNV Loss 17160897
nsv900069 CNV Gain 21882294
esv2747389 CNV Deletion 23290073
esv2007070 CNV Deletion 18987734
esv2747390 CNV Deletion 23290073
nsv64013 CNV Loss 16902084

Relevant External Links for CDADC1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDADC1 Gene

Disorders for CDADC1 Gene

Relevant External Links for CDADC1

Genetic Association Database (GAD)

No disorders were found for CDADC1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CDADC1 Gene

Publications for CDADC1 Gene

  1. NYD-SP15: a novel gene potentially involved in regulating testicular development and spermatogenesis. (PMID: 16955368) Liu Q. … Li J. (Biochem. Genet. 2006) 3 4
  2. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PMID: 17903302) Levy D. … Mitchell G.F. (BMC Med. Genet. 2007) 48
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for CDADC1 Gene

Sources for CDADC1 Gene

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