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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CD99 Gene

protein-coding   GIFtS: 65
GCID: GC0XP002602

CD99 Molecule

(Previous names: antigen identified by monoclonal antibodies 12E7, F21 and...)
(Previous symbol: MIC2)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CD99 Molecule1 2     HBA712
MIC21 2 3 5     MSK5X2
CD99 Antigen1 2 3     Antigen Identified By Monoclonal 12E7, Y Homolog2
MIC2X2 3 5     MIC2 (Monoclonal Antibody 12E7)2
Antigen Identified By Monoclonal Antibodies 12E7, F21 And O131 2     Surface Antigen MIC22
MIC2Y2 3     12E73
E2 Antigen2 3     Protein MIC23
T-Cell Surface Glycoprotein E22 3     

External Ids:    HGNC: 70821   Entrez Gene: 42672   Ensembl: ENSG000000025867   OMIM: 3134705   UniProtKB: P142093   

Export aliases for CD99 gene to outside databases

Previous GC identifers: GC0XP001778 GC0XP002139 GC0XP002204 GC0YP002602 GC0XP000550


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD99 Gene:
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion,
ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In
addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an
oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This
gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Apr 2013)

GeneCards Summary for CD99 Gene: 
CD99 (CD99 molecule) is a protein-coding gene. Diseases associated with CD99 include onychomatricoma, and testicular fibroma, and among its related super-pathways are GnRH Signaling.

UniProtKB/Swiss-Prot: CD99_HUMAN, P14209
Function: Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a
role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane.
Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity)

Gene Wiki entry for CD99 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_167197.1  NC_000024.9  NT_167205.1  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD99 gene promoter:
         c-Fos   AP-1   FOXO4   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD99 promoter sequence
   Search SABiosciences Chromatin IP Primers for CD99

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD99


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.32 and Yp11.3   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.32 and Yp11.3

CD99 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD99 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP002602:  view genomic region     (about GC identifiers)

Start:
2,609,220 bp from pter      End:
2,659,350 bp from pter
Size:
50,131 bases      Orientation:
plus strand

1 alternative location:
ChrY+ 2,559,228-2,609,350     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CD99_HUMAN, P14209 (See protein sequence)
Recommended Name: CD99 antigen precursor  
Size: 185 amino acids; 18848 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Miscellaneous: The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y
chromosomes
Secondary accessions: A6NIW1 O00518 Q6ICV7
Alternative splicing: 3 isoforms:  P14209-1   P14209-2   P14209-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CD99: NX_P14209

Explore proteomics data for CD99 at MOPED 

Post-translational modifications:

  • UniProtKB: Extensively O-glycosylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P14209

  • CD99 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CD99 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001116370.1  NP_001264639.1  NP_002405.1  

    ENSEMBL proteins: 
     ENSP00000370588   ENSP00000370582   ENSP00000370579   ENSP00000370573   ENSP00000405544  
     ENSP00000370570  

    Human Recombinant Protein Products for CD99: 
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    Novus Biologicals CD99 Lysates
    Sino Biological Recombinant Protein for CD99
    Sino Biological Cell Lysate for CD99 
    ProSpec Recombinant Protein for CD99
    Cloud-Clone Corp. Proteins for CD99 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm TAS2479542
    GO:0005886plasma membrane TAS2465491
    GO:0005887integral to plasma membrane TAS2465491

    CD99 for ontologies           About GeneDecksing



    CD99 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    PAR1: Pseudoautosomal regions / PAR1

    1 InterPro protein domain:
     IPR022078 CD99L2

    Graphical View of Domain Structure for InterPro Entry P14209

    ProtoNet protein and cluster: P14209

    UniProtKB/Swiss-Prot: CD99_HUMAN, P14209
    Similarity: Belongs to the CD99 family


    CD99 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CD99_HUMAN, P14209
    Function: Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a
    role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane.
    Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity)

    Phenotypes:
         4 GenomeRNAi human phenotypes for CD99:

     Actin fiber cells  G0/1 arrest  Increased G1 DNA content  Increased cell size 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CD99 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD99

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD99 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD99 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD99


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CD99 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Integrin Pathway
    Transendothelial Migration of Leukocytes0.38
    2Leukocyte transendothelial migration
    Leukocyte transendothelial migration
    3Cell adhesion molecules (CAMs)
    Cell adhesion molecules (CAMs)

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for CD99
        Transendothelial Migration of Leukocytes



    2         Kegg Pathways  (Kegg details for CD99):
        Cell adhesion molecules (CAMs)
    Leukocyte transendothelial migration


    CD99 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CD99

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/12 Interacting proteins for CD99 (P142092, 3 ENSP000003705884) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN1Q9UMX02, 3, ENSP000003655764MINT-67309 I2D: score=5 STRING: ENSP00000365576
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2860903 I2D: score=3 STRING: ENSP00000357292
    ANXA2P073553, ENSP000003460324I2D: score=3 STRING: ENSP00000346032
    PPIAP629373, ENSP000004194254I2D: score=3 STRING: ENSP00000419425
    KPNB1Q149743, ENSP000002901584I2D: score=2 STRING: ENSP00000290158
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--

    CD99 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CD99 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CD99

    3 Novoseek inferred chemical compound relationships for CD99 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    paraffin 18.5 5 9343323 (4)
    phosphatidylserine 13.7 2 8399135 (2)
    vegf 0 3 17571460 (3)

    Search CenterWatch for drugs/clinical trials and news about CD99

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CD99 gene (3 alternative transcripts): 
    NM_001122898.1  NM_001277710.1  NM_002414.3  

    Unigene Cluster for CD99:

    CD99 molecule
    Hs.653349  [show with all ESTs]
    Unigene Representative Sequence: BF341535
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381192(uc004cqm.3 uc010nda.3 uc004cqn.3) ENST00000381187
    ENST00000381184 ENST00000482405 ENST00000381180 ENST00000449611 ENST00000482293
    ENST00000497752 ENST00000381177
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK309517.1 AK313617.1 BC002584.2 BC003147.1 BC010109.2 BC021620.1 BC024310.1 CR450286.1 
    M16279.1 U82164.1 X16996.1 

    24/55 DOTS entries (see all 55):

    DT.100882403  DT.95269792  DT.100882412  DT.40208580  DT.120654807  DT.121277500  DT.100811686  DT.75190973 
    DT.100882404  DT.99931808  DT.101968474  DT.95269789  DT.100882411  DT.102834185  DT.100882391  DT.120654775 
    DT.100837765  DT.120654790  DT.120654796  DT.121277568  DT.100882395  DT.91685405  DT.91769523  DT.95269779 

    24/696 AceView cDNA sequences (see all 696):

    BQ053378 CF128610 BM352800 CA951119 AL558448 AL551252 AW384184 AL548661 
    BM508233 BU727501 CA412512 AI920891 CR606510 BM716604 BM352485 T51012 
    BM704863 BQ226154 CR612683 CK819227 AL550748 BU076703 M16279 CR598638 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CD99 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d
    SP1:                          -                                               -     -                                 
    SP2:                          -                                               -     -                                 
    SP3:                          -                                                                                       
    SP4:                          -                                               -                                       
    SP5:                          -     -                                         -     -                                 


    ECgene alternative splicing isoforms for CD99

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CD99 expression in normal human tissues (normalized intensities)      CD99 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGATGTGAAA
    CD99 Expression
    About this image


    CD99 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Endoderm (Gastrulation Derivatives)
             Definitive endoderm-like cells ( Generation of mesendoderm and definitive endoderm...
     
     Testis (Reproductive System)

    See CD99 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CD99

    SOURCE GeneReport for Unigene cluster: Hs.653349
        SABiosciences Expression via Pathway-Focused PCR Array including CD99: 
              Tight Junctions in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD99

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CD99 gene from 4/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia CD991 CD99 molecule 73.05(n)
    70.99(a)
      609832  XM_847176.2  XP_852269.2 
    chicken
    (Gallus gallus)
    Aves CD991 CD99 molecule 57.81(n)
    49.65(a)
      418662  NM_001198651.1  NP_001185580.1 
    lizard
    (Anolis carolinensis)
    Reptilia CD996
    CD99 molecule
    45(a)
    1 ↔ 1
    3(113837936-113878121)
    zebrafish
    (Danio rerio)
    Actinopterygii cd996
    CD99 molecule
    26(a)
    1 ↔ 1
    1(33020650-33045276)


    ENSEMBL Gene Tree for CD99 (if available)
    TreeFam Gene Tree for CD99 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CD99 gene
    1 SIMAP similar gene for CD99 using alignment to 5 protein entries:     CD99_HUMAN (see all proteins):
    CD99L2

    CD99 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CD99
    PGOHUM00000241627


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    2 SNPs in CD99 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0147334
    ----see VAR_0147332 M V mis40--------
    VAR_0147344
    ----see VAR_0147342 N I mis40--------

    HapMap Linkage Disequilibrium report for CD99 (2609220 - 2659350 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CD99:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv29996CNV Loss17803354
    esv34985CNV Gain17911159
    esv29994CNV Gain17803354
    esv2752318CNV Gain17911159
    dgv2432e1CNV Complex17122850


    Locus Specific Mutation Databases (LSDB): CD99
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CD99
    DNA2.0 Custom Variant and Variant Library Synthesis for CD99

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 313470    OMIM disorders: --

    20/68 diseases for CD99 (see all 68):    About MalaCards
    onychomatricoma    testicular fibroma    pediatric lymphoma    small cell osteogenic sarcoma
    extraosseous ewing's sarcoma    malignant teratoma    central nervous system cancer    nervous system cancer
    pulmonary vein stenosis    embryonal cancer    spindle cell lipoma    peripheral primitive neuroectodermal tumor
    desmoplastic small round cell tumor    chikungunya    primitive neuroectodermal tumor    lymphoblastic lymphoma
    hepatitis e    pleomorphic carcinoma    thymic epithelial tumor    teratoma

    8 diseases from the University of Copenhagen DISEASES database for CD99:
    Peripheral primitive neuroectodermal tumor     Primitive neuroectodermal tumor     Sarcoma     Testicular fibroma
    Juvenile type testicular granulosa cell tumor     Synovial sarcoma     Small cell osteogenic sarcoma     Rhabdomyosarcoma

    CD99 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/20 Novoseek inferred disease relationships for CD99 gene (see all 20)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    peripheral neuroepithelioma 85.8 1 1848471 (1)
    ewings sarcoma 84.3 19 8150461 (5), 1848471 (3), 8163272 (2), 12724079 (1) (see all 11)
    sarcoma extraosseous ewings 71.7 2 12400989 (1)
    lymphoma lymphoblastic 61.6 4 8163272 (2), 9343323 (1)
    esthesioneuroblastoma 60.4 1 12724079 (1)
    rhabdomyosarcoma 41.8 1 8163272 (1)
    tumors 41.2 38 8150461 (4), 7627931 (3), 1848471 (2), 1988096 (2) (see all 23)
    stromal tumors 40.1 2 10374776 (1)
    hepatitis c 32 2 7689528 (1)
    epithelial tumor 25 4 10374776 (2)

    Genetic Association Database (GAD): CD99
    Human Genome Epidemiology (HuGE) Navigator: CD99 (1 document)

    Export disorders for CD99 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CD99 gene, integrated from 9 sources (see all 158):
    (articles sorted by number of sources associating them with CD99)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. (PubMed id 19723899)1, 4 Burkhardt J....Ahnert P. (2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product. (PubMed id 2479542)1, 2 Gelin C....Bernard A. (1989)
    4. Absence of methylation of a CpG-rich region at the 5' end of the MIC2 gene on the active X, the inactive X, and the Y chromosome. (PubMed id 2456574)1, 2 Goodfellow P.J....Goodfellow P.N. (1988)
    5. Molecular genetics of MIC2: a gene shared by the human X and Y chromosomes. (PubMed id 3472717)1, 2 Darling S.M....Goodfellow P.N. (1986)
    6. The association between CD99 and LMP-1 expression in nasopharyngeal carcinoma. (PubMed id 16614706)1, 9 Kim H.S....Park C.S. (2006)
    7. Quantitative analysis of XG blood group and CD99 antigens on human red cells. (PubMed id 10941840)1, 9 Fouchet C....Lopez C. (2000)
    8. CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion. (PubMed id 9278313)1, 9 Hahn J.H....Park S.H. (1997)
    9. Flow cytometric assessment of human MIC2 expression in bone marrow, thymus, and peripheral blood. (PubMed id 7506950)1, 9 Dworzak M.N....Gadner H. (1994)
    10. Immunoreactivity of CD99 in stomach cancer. (PubMed id 12172043)1, 9 Jung K.C....Park S.H. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4267 HGNC: 7082 AceView: CD99 Ensembl:ENSG00000002586 euGenes: HUgn4267
    ECgene: CD99 Kegg: 4267 H-InvDB: CD99

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CD99 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CD99 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CD99 gene:
    Search GeneIP for patents involving CD99

    GeneCards and IP:
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