Aliases for CD96 Gene
External Ids for CD96 Gene
Previous GeneCards Identifiers for CD96 Gene
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD96 Gene
CD96 (CD96 Molecule) is a Protein Coding gene. Diseases associated with CD96 include c syndrome and second-degree atrioventricular block. Among its related pathways are Immune System and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
UniProtKB/Swiss-Prot for CD96 Gene
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation