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CD9 Gene

protein-coding GIFtS: 65

GC12P006179

CD9 molecule
(Previous name: CD9 antigen (p24) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: MIC3)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
5H9 ^²
BA2 ^¹, ²
BTCC-1 ^²
DRAP-27 ^²
GIG2 ^²
MIC3 ^², ³, ⁵
MRP-1 ^¹, ², ³
OTTHUMP00000041574 ^²
OTTHUMP00000041576 ^²
P24 ^¹, ²
TSPAN29 ^¹, ², ³
Tetraspanin-29 ^³
Tspan-29 ^³
p24 ^³

Descriptions
5H9 antigen ^², ³
CD9 antigen ^², ³
CD9 antigen (p24) ^¹, ²
CD9 molecule ^²
Cell growth-inhibiting gene 2 protein ^³
Leukocyte antigen MIC3 ^², ³
Motility-related protein ^³
antigen defined by monoclonal antibody 602-29 ^²
growth-inhibiting gene 2 protein ^²
motility related protein ^²
motility related protein-1 ^²
p24 antigen ^²

External Ids
HGNC: 1709¹
Entrez Gene: 928²
UniProtKB: P21926³
Ensembl: ENSG00000010278⁷

Search outside databases for aliases for CD9 gene

Previous GC identifers: GC12P006164 GC12P006284

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CD9:

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the

tetraspanin family. Most of these members are cell-surface proteins that are characterized by the

presence of four hydrophobic domains. The proteins mediate signal transduction events that play a

role in the regulation of cell development, activation, growth and motility. This encoded protein

is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4

superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet

activation and aggregation. In addition, the protein appears to promote muscle cell fusion and

support myotube maintenance. [provided by RefSeq]

UniProtKB/Swiss-Prot: CD9_HUMAN, P21926

Function: Involved in platelet activation and aggregation. Regulates paranodal junction formation.

Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion

Gene Wiki entry for CD9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CD9 gene

Entrez Gene cytogenetic band: 12p13.3 Ensembl cytogenetic band: 12p13.31 HGNC cytogenetic band: 12p13

CD9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P006179: (about GC identifiers)

Start:	6,179,142 bp from pter
End:	6,222,635 bp from pter
Size:	43,494 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_009759.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CD9_HUMAN, P21926 (See protein sequence)

Recommended Name: CD9 antigen

Size: 228 amino acids; 25416 Da

Subunit: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers

with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1.

Interacts directly with IGSF8

Subcellular location: Membrane; Multi-pass membrane protein

Secondary accessions: Q5J7W6 Q96ES4

Post-translational modifications:

Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry

covalently linked fatty acids¹

REFSEQ proteins: NP_001760.1

ENSEMBL proteins:

ENSP00000371955 ENSP00000371958 ENSP00000009180 ENSP00000371959

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD9)
	Human Recombinant Proteins from Abnova (CD9)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	NAS	6198179
GO:0005887	integral to plasma membrane	NAS	2037603
GO:0031092	platelet alpha granule membrane	EXP	10515286

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Antibodies for CD9:

	Invitrogen Antibodies for CD9
	Millipore Mono- and Polyclonal Antibodies for the study of CD9
	Sigma-Aldrich Antibodies for CD9
	R&D Systems Antibodies for CD9
	Antibodies from Abcam (CD9), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CD9)
	Novus Biologicals Antibodies for CD9

Assays for CD9:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P21926

ProtoNet protein and cluster: P21926

1 Blocks protein family: IPB000301 Transmembrane four family signature

UniProtKB/Swiss-Prot: CD9_HUMAN, P21926

Similarity: Belongs to the tetraspanin (TM4SF) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD9)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001769

Applied Biosystems Silencer® siRNAs for CD9

Sigma-Aldrich siRNA and siRNA Panels for CD9

Sigma-Aldrich shRNA Panels and shRNA for CD9

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001769
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001769
untagged cDNA clones in CMV expression vector (see all 2): NM_001769

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001769

UniProtKB/Swiss-Prot: CD9_HUMAN, P21926

Function: Involved in platelet activation and aggregation. Regulates paranodal junction formation.

Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion

Genatlas biochemistry entry for CD9:

cell differentiation antigen CD9 (p34),24kDa,membrane glycoprotein,single chain,identified by

monoclonal antibodies ALB6,BLI16,FMC56

6 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Cd9):

growth/size	hematopoietic system	immune system	reproductive system	respiratory system
skeleton

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	11278880 11504738

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for CD9

5/95 Interacting proteins for CD9 (ENSP00000009180³) via UniProtKB, MINT, and/or STRING (see all 95 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ITGB1	ENSP00000364094³	STRING (score=.999)
ITGA3	ENSP00000007722³	STRING (score=.997)
PTGFRN	ENSP00000358485³	STRING (score=.991)
ITGA6	ENSP00000264106³	STRING (score=.982)
CD19	ENSP00000313419³	STRING (score=.981)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006928	cell motion	IDA	8478605
GO:0007155	cell adhesion	IDA	7511626
GO:0007342	fusion of sperm to egg plasma membrane	IDA	14575715
GO:0030168	platelet activation	NAS	2037603
GO:0030913	paranodal junction assembly	ISS	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CD9
10/36 Novoseek chemical compound relationships for CD9 gene (see all 36 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neopterin	68.25	29	2214610 (3), 7529507 (2), 8097095 (2), 2126281 (2) (see all 24)
emulphor	49.70	2	12705892 (1), 9804823 (1)
mdms	38.81	2	9568543 (1), 11897037 (1)
rantes	21.89	1	17331032 (1)
thromboxane	11.19	4	2306515 (1), 8217830 (1), 1832992 (1)
ribonucleic acid	4.80	4	9202611 (2), 9202613 (1), 8804331 (1)
adp	3.20	3	2317202 (1), 2306515 (1)
toluidine	2.54	4	7524750 (1), 9472805 (1), 9129208 (1)
fatty acid	1.41	1	10224565 (1)
cholesterol	1.34	5	15004227 (1), 17644758 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD9)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001769

Sigma-Aldrich siRNA and siRNA Panels for CD9

Sigma-Aldrich shRNA Panels and shRNA for CD9

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001769

REFSEQ mRNAs for CD9 gene:

NM_001769.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001769

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001769
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001769
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001769

Additional cDNA sequence:

AB079244.1 AK025016.1 AK296332.1 AK296894.1 AK298431.1 AK308700.1 AK311020.1 AK315219.1

AY423720.1 AY966455.1 BC011988.1 CR598565.1 CR599016.1 CR599322.1 CR619299.1 L34068.1

M38690.1 X60111.1

24/29 DOTS entries (see all 29 ):

DT.100849778 DT.453110 DT.100849783 DT.95222449 DT.95214031 DT.92043609 DT.95193123 DT.121110412

DT.121110457 DT.91867150 DT.97860873 DT.100849774 DT.100031871 DT.121110448 DT.121110399 DT.121110410

DT.100849776 DT.121110346 DT.121110398 DT.121110426 DT.91674152 DT.95213964 DT.95214018 DT.95214065

9 AceView cDNA sequences:

CR599322 CR619299 L34068 BC011988 NM_001769 CR598565 X60111 CR599016

M38690

highest scoring ESTs for CD9:

M38690 AA173738 AA524591 AA527819 AA640721 AA640905 AW844485 AW950198 BC011988 BE002765

Unigene Cluster for CD9:

CD9 molecule

Hs.114286 [show with all ESTs]

Unigene Representative Sequence: AK025016

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CD9 (see all 8 )

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	^	3	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9a	·	9b	·	9c	^	10	^	11a	·	11b	^	12
SP1:													-				-				-		-
SP2:													-				-				-
SP3:							-						-				-				-		-
SP4:																	-				-		-
SP5:																					-		-

About this scheme

ECgene alternative splicing isoforms for CD9

4 Ensembl transcripts including schematic representations:

ENST00000382515 ENST00000382518 ENST00000009180 ENST00000382519

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CD9 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CD9

¹ / ² / ³

3 probe-sets matching CD9 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39389_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M38690	1.00	1.00	1.00	1
201005_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001769	0.60	1.00	0.82	1
201005_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AAGATTGGTG

SOURCE GeneReport for Unigene cluster: Hs.114286
Expression variation in blood from EXPOLDB for CD9
UniProtKB/Swiss-Prot: CD9_HUMAN, P21926
Tissue specificity: Expressed by a variety of hematopoietic and epithelial cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CD9 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CD9¹	--	CD9 molecule	88.89(n) 92.16(a)	611695 XM_849393.1 XP_854486.1
chimpanzee (Pan troglodytes)	CD9¹	--	CD9 molecule	99.56(n) 99.56(a)	451775 XM_508947.2 XP_508947.2
cow (Bos taurus)	CD9¹	--	CD9 molecule	87.32(n) 84.51(a)	280746 NM_173900.2 NP_776325.1
mouse (Mus musculus)	Cd9^{1, 5}	6 (58.00 cM)⁵	CD9 antigen^{1, 5}	85.99(n)¹ 89.82(a)¹	12527¹ NM_007657.3¹ NP_031683.1¹ AK002251⁵ AK012793⁵ (see all 12)
chicken (Gallus gallus)	CD9¹	--	CD9 molecule	72.2(n) 73.99(a)	395527 NM_204762.1 NP_990093.1

About this table Species with no ortholog for CD9

ENSEMBL Gene Tree for CD9

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CD9 gene

TSPAN2² CD81²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/292 NCBI SNPs in CD9 are shown (see all 292 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 147)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs797773^1,2	A,C,F,H,O	6177827(+)	`TGCCCC/TGCCTT`	1	--	ng5¹		10	MN EU EA WA NA	1062
	rs10774419^1,2	A,C,F,H	6218155(+)	`taaagG/Aattct`	1	--	ng3¹		6	NS EU EA WA	506
	rs3181157^1,2	A,C,F,H	6178784(+)	`AAAGAC/TCCACA`	1	--	ng5¹		8	NA EU EA WA NS	586
--	rs11568276^1,2	C,F	6218129(+)	`TGAAGG/-AAATC`	1	--	ng3¹		2	NS	88
--	rs11568191^1,2	C,F	6178541(+)	`GATAAT/CAAACA`	1	--	ng5¹		8	NS	744
	rs3181158^1,2	H	6179107(+)	`CTGGGG/CCAACT`	1	--	ng5¹		4	NA EU EA	332
--	rs11568192^1,2	F	6178811(+)	`CGTTGG/CGGGGG`	1	--	ng5¹ tfbs³		2	NS	84
--	rs11568195^1,2	F	6178847(+)	`GCCAGC/AGAGTG`	1	--	ng5¹		2	NS	84
--	rs11574683^1,2	F	6179864(+)	`CGCCAG/ATCCCA`	1	--	ut5¹ ese³		1	NA	40
--	rs11539946^1,2	H	6204892(+)	`GGCTCC/GGATTC`	1	R/G	mis¹ ese³		4	EU EA WA	402

About this table

HapMap Linkage Disequilibrium images for CD9 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 143030

10/72 Novoseek disease relationships for CD9 gene (see all 72 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
immunodeficiency	87.36	153	9419745 (2), 12624024 (2), 1677177 (2), 1323624 (2) (see all 99)
hiv infections	81.89	78	9403423 (3), 14646380 (2), 8207645 (2), 8604210 (2) (see all 67)
aids-related complex	81.67	5	1506978 (1), 2123627 (1), 8811465 (1), 1974725 (1)
aids	73.56	82	10609356 (3), 11766280 (2), 1351128 (2), 11109648 (2) (see all 59)
viremia	63.77	13	7906292 (1), 9845513 (1), 14646380 (1), 8097416 (1) (see all 13)
pediatric aids	54.20	2	9041402 (1), 9420321 (1)
opportunistic infections	54.05	2	2227628 (1), 9586886 (1)
virus infection	52.16	19	8655993 (1), 14872188 (1), 2186629 (1), 2227628 (1) (see all 19)
vertical transmission	49.49	3	8784370 (1), 8161446 (1), 8280414 (1)
kaposi sarcoma	37.34	2	14559986 (2)

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1 PharmGKB disease relationship for CD9 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

Human Genome Epidemiology Navigator: CD9 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/572 PubMed articles for CD9 gene (see all 572 ):

Organization of the human CD9 gene. (PubMed id 8486348)^{1, 3, 4} Rubinstein E.... Boucheix C. (1993)
Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking. (PubMed id 14556650)^{1, 3, 4} Kovalenko O.V.... Hemler M.E. (2004)
Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation. (PubMed id 11959120)^{1, 3, 4} Charrin S....Rubinstein E. (2002)
Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. (PubMed id 8478605)^{1, 3, 4} Ikeyama S.... Miyake M. (1993)
Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility. (PubMed id 1720807)^{1, 3, 4} Miyake M.... Ikeyama S. (1991)
Molecular cloning of the CD9 antigen. A new family of cell surface proteins. (PubMed id 1840589)^{1, 3, 4} Boucheix C.... Uzan G. (1991)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The tetraspanin CD9 is preferentially expressed on the human CD4(+)CD45RA+ naive T cell population and is involved in T cell activation. (PubMed id 15196249)^{3, 4} Kobayashi H.... Morimoto C. (2004)
Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion. (PubMed id 14575715)^{3, 4} Higginbottom A.... Monk P.N. (2003)
EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily. (PubMed id 11504738)^{3, 4} Stipp C.S.... Hemler M.E. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 928	HGNC: 1709	AceView: CD9	Ensembl:ENSG00000010278	euGenes: HUgn928
ECgene: CD9	H-InvDB: CD9

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CD9	Genetics and Cytogenetics in Oncology and Haematology
SeattleSNPs	http://pga.gs.washington.edu/data/cd9/

Licensable Technologies for CD9
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CD9:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CD9-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CD9		Antibodies for CD9
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CD9		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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CD9 Gene at Home site.
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CD9 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for CD9

Summaries
for CD9

Genomic Location
for CD9

Proteins
for CD9

Protein Domains/
Families
for CD9

Gene Function
for CD9

Pathways & Interactions
for CD9

Drugs & Compounds
for CD9

Transcripts
for CD9

Expression
for CD9

Orthologs
for CD9

Paralogs
for CD9

SNPs/Variants
for CD9

Disorders & Mutations
for CD9

Medical News
for CD9

Publications
for CD9

Search for CD9

Genome Databases showing CD9

Other Databases showing CD9

Specialized Databases showing CD9

Licensable Technologies
for CD9

Services
for CD9

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CD9 (Gene Symbol)
5H9
BA2
BTCC-1
DRAP-27
GIG2
MIC3
MRP-1
OTTHUMP00000041574
OTTHUMP00000041576
P24
TSPAN29
Tetraspanin-29
Tspan-29
p24
5H9 antigen
CD9 antigen
CD9 antigen (p24)
CD9 molecule
Cell growth-inhibiting gene 2 protein
Leukocyte antigen MIC3
Motility-related protein
antigen defined by monoclonal antibody 602-29
growth-inhibiting gene 2 protein
motility related protein
motility related protein-1
p24 antigen

CD9 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor CD9

Summariesfor CD9

Genomic Locationfor CD9

Proteinsfor CD9

Protein Domains/Familiesfor CD9

Gene Functionfor CD9

Pathways & Interactionsfor CD9

Drugs & Compoundsfor CD9

Transcriptsfor CD9

Expression for CD9

Orthologsfor CD9

Paralogsfor CD9

SNPs/Variantsfor CD9

Disorders & Mutationsfor CD9

Medical Newsfor CD9

Publicationsfor CD9

Search for CD9

Genome Databases showing CD9

Other Databases showing CD9

Specialized Databases showing CD9

Licensable Technologiesfor CD9

Servicesfor CD9

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CD9

Summaries
for CD9

Genomic Location
for CD9

Proteins
for CD9

Protein Domains/
Families
for CD9

Gene Function
for CD9

Pathways & Interactions
for CD9

Drugs & Compounds
for CD9

Transcripts
for CD9

Expression
for CD9

Orthologs
for CD9

Paralogs
for CD9

SNPs/Variants
for CD9

Disorders & Mutations
for CD9

Medical News
for CD9

Publications
for CD9

Licensable Technologies
for CD9

Services
for CD9