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Aliases for CD8BP Gene

Aliases for CD8BP Gene

  • CD8b Molecule Pseudogene 2 3 5
  • CD8B2 3 4
  • CD8 Antigen, Beta Polypeptide 2, Pseudogene (P37) 2
  • CD8 Antigen, Beta Polypeptide Pseudogene 3
  • CD8b Pseudogene 4

External Ids for CD8BP Gene

Previous HGNC Symbols for CD8BP Gene

  • CD8B2

Previous GeneCards Identifiers for CD8BP Gene

  • GC02P107103

Summaries for CD8BP Gene

GeneCards Summary for CD8BP Gene

CD8BP (CD8b Molecule Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for CD8BP Gene

  • Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD8BP Gene

Genomics for CD8BP Gene

Regulatory Elements for CD8BP Gene

Promoters for CD8BP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CD8BP on UCSC Golden Path with GeneCards custom track

Genomic Location for CD8BP Gene

Chromosome:
2
Start:
106,487,368 bp from pter
End:
106,507,681 bp from pter
Size:
20,314 bases
Orientation:
Plus strand

Genomic View for CD8BP Gene

Genes around CD8BP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CD8BP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CD8BP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CD8BP Gene

Proteins for CD8BP Gene

  • Protein details for CD8BP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJW9-CD8BL_HUMAN
    Recommended name:
    Putative T-cell surface glycoprotein CD8 beta-2 chain
    Protein Accession:
    A6NJW9

    Protein attributes for CD8BP Gene

    Size:
    211 amino acids
    Molecular mass:
    23768 Da
    Quaternary structure:
    • In general heterodimer of an alpha and a beta chain linked by two disulfide bonds.

neXtProt entry for CD8BP Gene

Proteomics data for CD8BP Gene at MOPED

Post-translational modifications for CD8BP Gene

No Post-translational modifications

No data available for DME Specific Peptides for CD8BP Gene

Domains & Families for CD8BP Gene

Protein Domains for CD8BP Gene

Suggested Antigen Peptide Sequences for CD8BP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJW9

UniProtKB/Swiss-Prot:

CD8BL_HUMAN :
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Domain:
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
genes like me logo Genes that share domains with CD8BP: view

No data available for Gene Families for CD8BP Gene

Function for CD8BP Gene

Molecular function for CD8BP Gene

UniProtKB/Swiss-Prot Function:
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity).

Animal Model Products

  • Taconic Biosciences Mouse Models for CD8BP

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CD8BP Gene

Localization for CD8BP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CD8BP Gene

Cell membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for CD8BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with CD8BP: view

No data available for Subcellular locations from COMPARTMENTS for CD8BP Gene

Pathways & Interactions for CD8BP Gene

SuperPathways for CD8BP Gene

No Data Available

Interacting Proteins for CD8BP Gene

Gene Ontology (GO) - Biological Process for CD8BP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CD8BP Gene

Drugs & Compounds for CD8BP Gene

No Compound Related Data Available

Transcripts for CD8BP Gene

mRNA/cDNA for CD8BP Gene

(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CD8BP Gene

No ASD Table

Relevant External Links for CD8BP Gene

GeneLoc Exon Structure for
CD8BP
ECgene alternative splicing isoforms for
CD8BP

Expression for CD8BP Gene

mRNA expression in normal human tissues for CD8BP Gene

Protein differential expression in normal tissues from HIPED for CD8BP Gene

This gene is overexpressed in Tlymphocyte (58.4) and Peripheral blood mononuclear cells (10.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CD8BP Gene



genes like me logo Genes that share expression patterns with CD8BP: view

Protein tissue co-expression partners for CD8BP Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CD8BP Gene

Orthologs for CD8BP Gene

Evolution for CD8BP Gene

ENSEMBL:
Gene Tree for CD8BP (if available)
TreeFam:
Gene Tree for CD8BP (if available)

No data available for Orthologs for CD8BP Gene

Paralogs for CD8BP Gene

(3) SIMAP similar genes for CD8BP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CD8BP: view

No data available for Paralogs for CD8BP Gene

Variants for CD8BP Gene

Relevant External Links for CD8BP Gene

HapMap Linkage Disequilibrium report
CD8BP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CD8BP Gene

Disorders for CD8BP Gene

No disorders were found for CD8BP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for CD8BP Gene

Publications for CD8BP Gene

  1. Recent duplication of the two human CD8 beta-chain genes. (PMID: 1541829) Nakayama K. … Nakauchi H. (J. Immunol. 1992) 2 3 4 67
  2. Chromosomal mapping of the second human CD8B gene locus. (PMID: 8575821) Zhang X.L. … Chamberlain J.W. (Immunogenetics 1996) 3
  3. Duplication of the CD8 beta-chain gene as a marker of the man-gorilla-chimpanzee clade. (PMID: 8346216) Delarbre C. … Gachelin G. (Proc. Natl. Acad. Sci. U.S.A. 1993) 3
  4. Transcriptional diversity at the duplicated human CD8 beta loci. (PMID: 8436166) DiSanto J.P. … Flomenberg N. (Eur. J. Immunol. 1993) 3
  5. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 3

Products for CD8BP Gene

Sources for CD8BP Gene

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