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Aliases for CD8BP Gene

Aliases for CD8BP Gene

  • CD8b Molecule Pseudogene 2 3
  • CD8B2 3 4
  • CD8 Antigen, Beta Polypeptide 2, Pseudogene (P37) 2
  • CD8 Antigen, Beta Polypeptide Pseudogene 3
  • CD8b Pseudogene 4

External Ids for CD8BP Gene

Previous HGNC Symbols for CD8BP Gene

  • CD8B2

Previous GeneCards Identifiers for CD8BP Gene

  • GC02P107103

Summaries for CD8BP Gene

GeneCards Summary for CD8BP Gene

CD8BP (CD8b Molecule Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for CD8BP Gene

  • Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD8BP Gene

Genomics for CD8BP Gene

Genomic Location for CD8BP Gene

Start:
106,487,368 bp from pter
End:
106,507,681 bp from pter
Size:
20,314 bases
Orientation:
Plus strand

Genomic View for CD8BP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CD8BP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CD8BP Gene

No data available for Regulatory Elements for CD8BP Gene

Proteins for CD8BP Gene

  • Protein details for CD8BP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJW9-CD8BL_HUMAN
    Recommended name:
    Putative T-cell surface glycoprotein CD8 beta-2 chain
    Protein Accession:
    A6NJW9
    Secondary Accessions:

    Protein attributes for CD8BP Gene

    Size:
    211 amino acids
    Molecular mass:
    23768 Da
    Quaternary structure:
    • In general heterodimer of an alpha and a beta chain linked by two disulfide bonds

neXtProt entry for CD8BP Gene

Proteomics data for CD8BP Gene at MOPED

Post-translational modifications for CD8BP Gene

No data available for DME Specific Peptides for CD8BP Gene

Domains for CD8BP Gene

Protein Domains for CD8BP Gene

Suggested Antigen Peptide Sequences for CD8BP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJW9

UniProtKB/Swiss-Prot:

CD8BL_HUMAN :
  • A6NJW9
Domain:
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
genes like me logo Genes that share domains with CD8BP: view

No data available for Gene Families for CD8BP Gene

Function for CD8BP Gene

Molecular function for CD8BP Gene

UniProtKB/Swiss-Prot Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity).

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CD8BP Gene

Localization for CD8BP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CD8BP Gene

Cell membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CD8BP Gene COMPARTMENTS Subcellular localization image for CD8BP gene
Compartment Confidence
plasma membrane 5
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for CD8BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CD8BP: view

Pathways for CD8BP Gene

SuperPathways for CD8BP Gene

No Data Available

Interacting Proteins for CD8BP Gene

Gene Ontology (GO) - Biological Process for CD8BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002376 immune system process IEA --
genes like me logo Genes that share ontologies with CD8BP: view

No data available for Pathways by source for CD8BP Gene

Transcripts for CD8BP Gene

mRNA/cDNA for CD8BP Gene

(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CD8BP Gene

No ASD Table

Relevant External Links for CD8BP Gene

GeneLoc Exon Structure for
CD8BP
ECgene alternative splicing isoforms for
CD8BP

Expression for CD8BP Gene

mRNA expression in normal human tissues for CD8BP Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CD8BP Gene

genes like me logo Genes that share expressions with CD8BP: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CD8BP Gene

Orthologs for CD8BP Gene

Evolution for CD8BP Gene

ENSEMBL:
Gene Tree for CD8BP (if available)
TreeFam:
Gene Tree for CD8BP (if available)

No data available for Orthologs for CD8BP Gene

Paralogs for CD8BP Gene

Selected SIMAP similar genes for CD8BP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CD8BP: view

No data available for Paralogs for CD8BP Gene

Variants for CD8BP Gene

Relevant External Links for CD8BP Gene

HapMap Linkage Disequilibrium report
CD8BP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for CD8BP Gene

Disorders for CD8BP Gene

(1) University of Copenhagen DISEASES for CD8BP Gene

genes like me logo Genes that share disorders with CD8BP: view

No data available for UniProtKB/Swiss-Prot for CD8BP Gene

Publications for CD8BP Gene

  1. Recent duplication of the two human CD8 beta-chain genes. (PMID: 1541829) Nakayama K. … Nakauchi H. (J. Immunol. 1992) 2 3 4
  2. Transcriptional diversity at the duplicated human CD8 beta loci. (PMID: 8436166) DiSanto J.P. … Flomenberg N. (Eur. J. Immunol. 1993) 3 4
  3. Chromosomal mapping of the second human CD8B gene locus. (PMID: 8575821) Zhang X.L. … Chamberlain J.W. (Immunogenetics 1996) 3
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4
  5. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 3

Products for CD8BP Gene

Sources for CD8BP Gene

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