CD8B Gene
protein-coding GIFtS: 56
GCID: GC02M087042
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CD8b molecule(Previous names: CD8 antigen, beta polypeptide 1 (p37) )
(Previous symbol: CD8B1)
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Aliases
for CD8B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CD8b Molecule1 2 | | LYT32 | | CD8B11 2 3 5 | | P372 | | CD8 Antigen, Beta Polypeptide 1 (P37)1 2 | | T Lymphocyte Surface Glycoprotein Beta Chain2 | | LEU22 | | T-Cell Surface Glycoprotein CD8 Beta Chain2 | | LY32 | | CD8b Antigen3 |
Export aliases for CD8B gene to outside databasesPrevious GC identifer: GC02M086895 |
Summaries
for CD8B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CD8B:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cellinteractions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the Tlymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules.The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alphaand one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinctmembrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has beenidentified. (provided by RefSeq, May 2010)
UniProtKB/Swiss-Prot: CD8B_HUMAN, P10966Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought toplay a role in the process of T-cell mediated killing
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Genomic Views
for CD8B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CD8B gene promoter:
Nkx3-1 v4 AML1a NF-AT AREB6 NF-AT4 NF-AT2 Nkx3-1 v3 NF-AT3 ZIC2/Zic2 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CD8B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD8B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p12 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p12CD8B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M087042: view genomic region
(about GC identifiers)
Start:
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87,042,460 bp from pter |
End:
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87,089,047 bp from pter |
Size:
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46,588 bases |
Orientation:
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minus strand |
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Proteins
for CD8B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CD8B_HUMAN, P10966 (See
protein sequence)Recommended Name: T-cell surface glycoprotein CD8 beta chain precursor Size: 210 amino acids; 23722 Da
Subunit: In general heterodimer of an alpha and a beta chain linked by two disulfide bonds
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 2: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 3: Secreted (Probable)
Subcellular location: Isoform 4: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 5: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 6: Secreted (Probable)
Subcellular location: Isoform 7: Secreted (Probable)
Subcellular location: Isoform 8: Secreted (Probable)
Sequence caution: Sequence=AAD13877.1; Type=Erroneous gene model prediction;
Secondary accessions: P14860 P14861 Q15980 Q496E0 Q496E1 Q496E2 Q9UDB4 Q9UDB5 Q9UDB6 Q9UDB7 Q9UDB8Q9UDB9 Q9UDC0 Q9UQ55Alternative splicing: 8 isoforms: P10966-1 P10966-2 P10966-3 P10966-4 P10966-6 P10966-7 P10966-8 P10966-9 (Ref.6 (AAI00915) sequence is in conflict in position: 213:I->V)Explore the universe of human proteins at neXtProt for CD8B: NX_P10966
Post-translational modifications:
Phosphorylated as a consequence of T-cell activation (Potential)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P10966
CD8B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001171571.1 NP_004922.1 NP_742099.1 NP_742100.1 NP_757362.1
ENSEMBL proteins: ENSP00000377356 ENSP00000340592 ENSP00000331172 ENSP00000375070 ENSP00000377358 ENSP00000394806 Reactome Protein details: P10966
Human Recombinant Protein Products for CD8B:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
CD8B for ontologies About GeneDecksing
CD8B Antibody Products:
Assay Products for CD8B: |
Protein
Domains /
Families
for CD8B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CD8B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P10966ProtoNet protein and cluster: P10966 2 Blocks protein families: IPB003599 Immunoglobulin subtype IPB013106 Immunoglobulin V-set
UniProtKB/Swiss-Prot: CD8B_HUMAN, P10966Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain |
Function
for CD8B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CD8B_HUMAN, P10966Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought toplay a role in the process of T-cell mediated killing Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CD8B for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CD8B:
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Cd8b1):
CD8B for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for CD8B: Cd8b1tm1Litt Cd8b1tm1Wpfl Cd8a/Cd8b1Cd8a/tm3Welm
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): CD8B (NM_172213) | |  | Sino Biological Human cDNA Clone for CD8B | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CD8B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD8B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD8B |
|
Pathways & Interactions
for CD8B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | HIV Infection | | | 3 | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | | | 4 | Immune response Antigen presentation by MHC class I | | | 5 | Degradation of CD4 | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CD8B
1 
Cell Signaling Technology (CST) Pathway for CD8B
1  GeneGo (Thomson Reuters) Pathway for CD8B
3  BioSystems Pathways for CD8B
5/10 
Reactome Pathways for CD8B (see all 10)
5 
Kegg Pathways (Kegg details for CD8B):
CD8B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CD8B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/35 Interacting proteins for CD8B (P109663 ENSP000003311724) via UniProtKB, MINT, STRING, and/or I2D (see all 35)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
CD8B for ontologies About GeneDecksing
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Drugs & Compounds
for CD8B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CD8B
Search CenterWatch for drugs/clinical trials and news about CD8B
|
Transcripts
for CD8B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CD8B gene (6 alternative transcripts): NM_001178100.1 NM_004931.4 NM_172101.3 NM_172102.3 NM_172213.3 NM_172099.2 Unigene Cluster for CD8B: CD8b molecule Hs.405667 [show with all ESTs]Unigene Representative Sequence: BX6471506 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393759(uc002srx.3 uc002srw.3 uc002sry.3) ENST00000349455
ENST00000331469 ENST00000390655(uc002srz.3 uc010yto.2) ENST00000393761(uc010fgt.3)
ENST00000431506
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): CD8B (NM_172213) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CD8B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD8B |
Additional cDNA sequence: AK303360.1 AK303595.1 BC100911.1 BC100912.2 BC100913.1 BC100914.1 BX647150.1 M36712.1 X13444.1 X13445.1 X13446.1 X13452.1 Y00805.1 13 DOTS entries: DT.454836 DT.91661340 DT.100022047 DT.95157768 DT.100754500 DT.100754501 DT.101959550 DT.40271550 DT.65287337 DT.40106278 DT.121025736 DT.121028764 DT.95298835 24/54 AceView cDNA sequences (see all 54): NM_172101 AA293671 NM_172213 NM_004931 NM_172099 BV175346 AW083057 BV180642 BF507921 NM_172102 AW511492 AW504863 AA291562 AW272094 BQ004743 M36712 X13446 AI338104 AA890171 CD556809 BX415552 X13444 Y00805 T28933
GeneLoc Exon Structure
|
Expression
for CD8B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CD8B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATCCTGAAA
About this image
See CD8B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CD8B
SOURCE GeneReport for Unigene cluster: Hs.405667
UniProtKB/Swiss-Prot: CD8B_HUMAN, P10966Tissue specificity: Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymusand peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells.Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells
SABiosciences Expression via Pathway-Focused PCR Arrays including CD8B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD8B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CD8B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD8B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD8B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD8B |
Orthologs
for CD8B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CD8B gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for CD8B (if available)
TreeFam Gene Tree for CD8B (if available) |
Paralogs
for CD8B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CD8B gene
3 SIMAP similar genes for CD8B using alignment to 3 protein entries: CD8B_HUMAN (see all proteins):CD8B1 CD81 CD8BP
CD8B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CD8B
PGOHUM00000250471
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Genomic Variants
for CD8B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CD8B (87042460 - 87089047 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CD8B
2 CNVs: 50581 68073 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD8B |
|
Disorders
/ Diseases
for CD8B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CD8B for disorders About GeneDecksing
OMIM gene information: 186730
OMIM disorders: --
5  diseases for CD8B: About MalaCardssupranuclear palsy progressive supranuclear palsy mucinous stomach adenocarcinoma tauopathy
immunodeficiency
Human Genome Epidemiology (HuGE) Navigator: CD8B (1 document)
Export disorders for CD8B gene to outside databases
|
Publications
for CD8B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CD8B gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with CD8B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Recent duplication of the two human CD8 beta-chain genes. (PubMed id 1541829)1, 2, 3 Nakayama K.... Nakauchi H. (1992)
- Transcriptional diversity at the duplicated human CD8 beta loci. (PubMed id 8436166)1, 2 DiSanto J.P.... Flomenberg N. (1993)
- A second subunit of CD8 is expressed in human T cells. (PubMed id 3145195)1, 2 Norment A.M. and Littman D.R. (1988)
- The human Lyt-3 molecule requires CD8 for cell surface expression. (PubMed id 3145196)1, 2 Disanto J.P.... Flomenberg N. (1988)
- A second chain of human CD8 is expressed on peripheral blood lymphocytes. (PubMed id 3264320)1, 2 Shiue L.... Parnes J.R. (1988)
- Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3. (PubMed id 11937547)1, 9 Kieffer L.J.... Kavathas P.B. (2002)
- Down-modulation of CD8I+I^ is a fundamental activity of primate lentiviral Nef proteins. (PubMed id 22013062)1 Heigele A....Kirchhoff F. (2012)
- Short communication: HIV antigen-specific reactivation of HIV infection from cellular reservoirs: implications in the settings of ther apeutic vaccinations. (PubMed id 21936714)1 Shete A....Paranjape R. (2012)
- Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef. (PubMed id 22844345)1 Saxena S.K....Nair M.P. (2012)
- Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence. (PubMed id 21922073)1 Tokarev A. and Guatelli J. (2011)
|
External Searches for CD8B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CD8B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CD8B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CD8B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CD8B | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/CD8 |
|
| | |
About This Section
| Patent Information for CD8B gene:
Search GeneIP for patents involving CD8B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CD8B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CD8B | | OriGene shRNA RFP for CD8B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CD8B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD8B | | | OriGene Protein Over-expression Lysate for CD8B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CD8B | | OriGene 3'-UTR Clone for CD8B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD8B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CD8B | | OriGene Custom Protein Services for CD8B | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CD8B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD8B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD8B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD8B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD8B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD8B |
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| | Antibodies & Assays for CD8B |
| | | | Search Tocris compounds for CD8B |
| |  |  |  |  | | | | |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD8B |
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