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CD63 Gene

protein-coding   GIFtS: 63

GC12M054405
CD63 molecule
(Previous name: CD63 antigen (melanoma 1 antigen) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: MLA1)
Services    

Aliases &
Descriptions
for CD63

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
Granulophysin 3
LAMP-3 2, 3
ME491 1, 2
MLA1 2, 3, 5
OMA81H 2, 3
TSPAN30 1, 2, 3
Tetraspanin-30 3
Tspan-30 3
granulophysin 2
tetraspanin-30 2
Descriptions
CD63 antigen 2, 3
CD63 antigen (melanoma 1 antigen) 1, 2
CD63 molecule 2
Lysosomal-associated membrane protein 3 3
Melanoma-associated antigen ME491 2, 3
Ocular melanoma-associated antigen 2, 3
lysosome-associated membrane glycoprotein 3 2
melanoma 1 antigen 2
melanoma-associated antigen MLA1 2
External Ids
HGNC: 16921
Entrez Gene: 9672
UniProtKB: P089623
Ensembl: ENSG000001354047
Search outside databases for aliases for CD63 gene

Previous GC identifers: GC12M056043 GC12M056192 GC12M055834

Summaries
for CD63

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for CD63:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the
tetraspanin family. Most of these members are cell-surface proteins that are characterized by the
presence of four hydrophobic domains. The proteins mediate signal transduction events that play a
role in the regulation of cell development, activation, growth and motility. This encoded protein
is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood
platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak
syndrome. Also this gene has been associated with tumor progression. The use of alternate
polyadenylation sites has been found for this gene. Alternative splicing results in multiple
transcript variants encoding different proteins. [provided by RefSeq]

UniProtKB/Swiss-Prot: CD63_HUMAN, P08962
Function: This antigen is associated with early stages of melanoma tumor progression. May play a
role in growth regulation

Gene Wiki entry for CD63

Genomic Location
for CD63

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the CD63 gene  

Entrez Gene cytogenetic band: 12q12-q13   Ensembl cytogenetic band:  12q13.2   HGNC cytogenetic band: 12q12-q13

CD63 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M054405:     (about GC identifiers)

Start:
 54,405,497 bp from pter
End:
 54,409,177 bp from pter
Size:
 3,681 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000012.10  NT_029419.11  

Proteins
for CD63

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: CD63_HUMAN, P08962 (See protein sequence)
Recommended Name: CD63 antigen  
Size: 238 amino acids; 25637 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass
membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in
Weibel-Palade bodies of endothelial cells. Located in platelet dense granules
Miscellaneous: Lack of expression of CD63 in platelets has been observed in a patient with
Hermansky-Pudlak syndrome (HPS). Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous,
rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to
platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from
defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and
lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of
premature death in individuals with HPS
Secondary accessions: Q5TZP3 Q9UCG6

REFSEQ proteins (2 alternative transcripts): 
NP_001035123.1  NP_001771.1  


ENSEMBL proteins: 
ENSP00000257857 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (CD63)
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005765 lysosomal membrane TAS1993697
GO:0005886 plasma membrane TAS8661157 9602068
GO:0005887 integral to plasma membrane TAS1993697
GO:0031902 late endosome membrane IEA--
About this table

Antibodies for CD63: 
Invitrogen Antibodies for CD63
Millipore Mono- and Polyclonal Antibodies for the study of CD63
Sigma-Aldrich Antibodies for CD63
R&D Systems Antibodies for CD63
Antibodies from Abcam (CD63), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (CD63)
Novus Biologicals Antibodies for CD63

Assays for CD63: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for CD63

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
3 InterPro domains/families:
 IPR018499 Tetraspanin
 IPR000301 Tetraspanin_sub
 IPR018503 Tetraspanin_CS


   GeneDecks  CD63 for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry P08962

ProtoNet protein and cluster: P08962

1 Blocks protein family: IPB000301 Transmembrane four family signature

UniProtKB/Swiss-Prot: CD63_HUMAN, P08962
Similarity: Belongs to the tetraspanin (TM4SF) family

Gene Function
for CD63

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (CD63)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001780

              Applied Biosystems Silencer® siRNAs for CD63

              Sigma-Aldrich siRNA and siRNA Panels for CD63  
                     Sigma-Aldrich shRNA for CD63  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for CD63
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001040034
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001040034
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001040034 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001780

UniProtKB/Swiss-Prot: CD63_HUMAN, P08962
Function: This antigen is associated with early stages of melanoma tumor progression. May play a
role in growth regulation

Genatlas biochemistry entry for CD63:
cell differentiation antigen CD63 (melanoma 1 antigen)

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Cd63):

behavior/neurologicalhomeostasis/metabolismrenal/urinary system

Pathways & Interactions
for CD63

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Invitrogen iPath™ Online BioAtlas - Pathway for CD63 (Maps provided by GeneGo):
 Integrin-mediated cell-matrix adhesion

   GeneDecks  CD63 for the pathways selected above  
About GeneDecksing

1 Millipore Pathway for CD63
 Selected targets of ESR1

   GeneDecks  CD63 for the pathways selected above  
About GeneDecksing

 Gene Network CentralTM Interacting Genes and Proteins Network for  CD63 


5/60 Interacting proteins for CD63 (ENSP000002578573 P089622) via UniProtKB, MINT, and/or STRING (see all 60 )
InteractantInteraction Details
GeneCardExternal ID(s)
TIMP1P010332STRING (score=.937) MINT-2981831 MINT-2981920 MINT-2981902 MINT-2981857 MINT-2981881
ITGB1P055562STRING (score=.995) MINT-2981958 MINT-2981939
ITGAMENSP000002874973STRING (score=.957)
LAMP2ENSP000003603963STRING (score=.93)
LAMP1ENSP000003332983STRING (score=.923)
About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0045807 positive regulation of endocytosis IEA--
About this table

Drugs & Compounds
for CD63

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CD63
10/18 Novoseek chemical compound relationships for CD63 gene (see all 18 )
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
mdmp 76.21 1 15668187 (1)
adp 61.62 18 7519037 (3), 7684475 (1), 8062509 (1), 18217151 (1) (see all 11)
fibrinogen 51.04 20 8062509 (2), 8115992 (2), 8560414 (2), 7519037 (2) (see all 12)
mannose 6-phosphate 43.24 2 11764278 (1), 17959629 (1)
thromboxane a2 41.44 1 8928869 (1)
rantes 40.40 10 12010805 (4), 15668187 (2), 15829999 (1), 12361207 (1)
p002 13.44 1 12579280 (1)
glucose 4.78 2 16131384 (2)
wortmannin 4.20 1 11764278 (1)
sucrose 2.16 1 18000614 (1)
About this table


Transcripts
for CD63

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (CD63)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001780

              Sigma-Aldrich siRNA and siRNA Panels for CD63  
                     Sigma-Aldrich shRNA for CD63  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001040034  NM_001780  

REFSEQ mRNAs for CD63 gene (2 alternative transcripts): 

NM_001040034.1   NM_001780.4   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001040034  NM_001780  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001040034
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001040034
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001040034 

Additional cDNA sequence: 

AF508304.1 AK311893.1 BC002349.2 BC013017.2 BT007073.1 BT020137.1 BT020138.1 CR542096.1 
CR593138.1 CR596146.1 CR596402.1 CR598829.1 CR600108.1 CR601904.1 CR602841.1 CR604098.1 
CR604975.1 CR606636.1 CR609892.1 CR612079.1 CR615604.1 CR617106.1 CR620394.1 CR620480.1 
CR623622.1 CR624383.1 CR625184.1 M58485.1 M59907.1 S93788.1 X07982.1 

24/45 DOTS entries (see all 45 ):

DT.100045710  DT.92464516  DT.92464504  DT.97806488  DT.97838247  DT.100703308  DT.92464535  DT.95133114 
DT.100892203  DT.100892222  DT.100892200  DT.100892213  DT.92464537  DT.100045720  DT.100892216  DT.95133186 
DT.121147407  DT.95069045  DT.97864758  DT.100034582  DT.101965775  DT.114899  DT.91941712  DT.92043966 

24/1311 AceView cDNA sequences (see all 1311 ):

BE872920 CR600108 AA121623 BQ887578 BF338855 BF526426 BU168899 AA365698 
BU155574 AA595126 BQ680306 AU129378 BM845558 CK905018 AA605231 BU174353 
AA373241 BU149931 BU542899 AA468398 BE277492 CR615604 AL582859 AA706268 

highest scoring ESTs for CD63:

AL540159 AL540160 AL540758 AL544125 AL546270 AL546303 AL549929 AL561656 AL701749 AU076987 

Unigene Cluster for CD63:

CD63 molecule
Hs.445570  [show with all ESTs]
Unigene Representative Sequence: BM809097


GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for CD63 (see all 11 )

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c · 13d
SP1:                                -     -     -           -     -                 -                             -                                       
SP2:                    -     -     -     -     -           -     -                 -                             -                                       
SP3:                                                        -     -     -           -                             -                                       
SP4:        -           -     -     -     -     -           -     -                 -                                                                     
SP5:                                      -     -           -     -                 -                                                                     

About this scheme

ECgene alternative splicing isoforms for CD63

1 Ensembl transcript including schematic representation:
ENST00000257857  

Expression
for CD63

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CD63 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for CD63

1 / 2 / 3

3 probe-sets matching CD63 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

37003_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 X62654 0.20 1.00 0.72 1

200663_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001780 0.60 1.00 0.82 1

200663_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
About this table
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: TCGAAGAACC

SOURCE GeneReport for Unigene cluster: Hs.445570

Expression variation in blood from EXPOLDB for CD63

UniProtKB/Swiss-Prot: CD63_HUMAN, P08962
Tissue specificity: Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells,
tissue macrophages

Orthologs
for CD63

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for CD63 gene from 5/12 species (see all 12 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 CD631   -- CD63 molecule 87.39(n)
89.92(a)		 474391  XM_531624.2  XP_531624.2 
chimpanzee
(Pan troglodytes)		 CD631   -- CD63 molecule 99.86(n)
99.58(a)		 451969  XM_509121.2  XP_509121.1 
cow
(Bos taurus)		 CD631   -- CD63 molecule 84.53(n)
84.81(a)		 404156  NM_205803.1  NP_991372.1 
rat
(Rattus norvegicus)		 Cd631   -- Cd63 molecule 80.39(n)
78.57(a)		 29186  NM_017125.2  NP_058821.1 
mouse
(Mus musculus)		 Cd631, 5 10 (72.00 cM)5
 CD63 antigen1, 5 81.93(n)1
79.41(a)1		 125121  NM_001042580.11  NP_001036045.11 
 AF1594275  AK0282205  (see all 40)
About this table        Species with no ortholog for CD63

ENSEMBL Gene Tree for CD63

Paralogs
for CD63

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for CD63 gene
CD822  TSPAN82  CD372  

SNPs/Variants
for CD63

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/39 NCBI SNPs in CD63 are shown (see all 39 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 53)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 12 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs7722551,2
A,C,F,H54410315(+) AGAGCA/TGAAGA 2 -- ng31 trp312Minor allele frequency- T:0.10EA NA EU WA 936
rs7722541,2
A,C,F,H54410599(-) CAGTCG/AACTGC 2 -- ng317Minor allele frequency- A:0.27EA NA EU WA 460
rs47591901,2
A,F,H54405511(+) AACTCA/GGACCA 2 -- ut313Minor allele frequency- G:0.01EA WA 290
rs115746571,2
H54406257(-) CATGTC/TGAAGA 2 S/L mis1 ese35Minor allele frequency- T:0.00NA EU EA WA 450
rs10500431,2
H54405634(-) TATCAG/AAAGTG 2 K/R mis1 ese35Minor allele frequency- A:0.00MN EU EA WA 590
rs130201,2
C,F,H54406790(-) AAAAAC/TAACCA 2 N/N syn19Minor allele frequency- T:0.04NA EU EA WA 678
rs31381311,2
F54408351(-) TTGCTC/GTACGT 2 L/L syn11Minor allele frequency- G:0.05NA 40
rs7722581,2
A,C,F,H,O54407035(-) TGACTT/CCTGTC 2 -- int18Minor allele frequency- C:0.06EU EA WA NA 598
--
rs22314671,2
A,F54406681(-) tggtgA/Gctcac 2 -- int11Minor allele frequency- G:0.05NA 40
rs22314641,2
F,H54406856(-) CCTCCG/ATACTC 2 -- int14Minor allele frequency- A:0.01EU EA WA 410
About this table

HapMap Linkage Disequilibrium images for CD63 (up to first 250kb)

Disorders & Mutations
for CD63

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 155740

10/23 Novoseek disease relationships for CD63 gene (see all 23 )

Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
hermansky-pudlak syndrome 79.49 5 7682577 (2), 1515640 (1)
platelet storage pool deficiency 69.09 1 1515640 (1)
melanoma 50.88 48 8630057 (6), 9120293 (5), 12740908 (2), 12150730 (2) (see all 20)
metastatic melanoma 20.97 1 8219756 (1)
von willebrand disease 19.46 1 10203098 (1)
preeclampsia 14.02 5 8062509 (2), 15118653 (2)
metastasis 13.50 6 15375577 (2), 12480921 (1), 12740908 (1), 7665237 (1)
niddm 10.23 1 16093733 (1)
diphtheria 7.65 1 11235900 (1)
cancer 4.09 3 12740908 (1), 10515601 (1), 15375577 (1)
About this table

Medical News
for CD63

(Possibly Related Articles in Doctor's Guide)
About This Section

Publications
for CD63

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

10/258 PubMed articles for CD63 gene (see all 258 ):

Search for CD63

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing CD63

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 967 HGNC: 1692 AceView: CD63 Ensembl:ENSG00000135404 euGenes: HUgn967
ECgene: CD63 H-InvDB: CD63

Other Databases showing CD63

(According to HUGE)
About This Section

   --

Specialized Databases showing CD63

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
ATLAS Chromosomes in Cancer entry for CD63 Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies
for CD63

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for CD63

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for CD63:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for CD63-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for CD63 Antibodies for CD63
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for CD63 Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
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