External Ids for CD6 Gene
Previous GeneCards Identifiers for CD6 Gene
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for CD6 Gene
CD6 (CD6 Molecule) is a Protein Coding gene. Diseases associated with CD6 include epidural neoplasm and lower lip cancer. Among its related pathways are Cell adhesion molecules (CAMs). GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is LOXL1.
UniProtKB/Swiss-Prot for CD6 Gene
Involved in cell adhesion. Binds to CD166