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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CD5L Gene

protein-coding   GIFtS: 59
GCID: GC01M157800

CD5 Molecule-Like

(Previous names: apoptosis inhibitor 6, CD5 antigen-like (scavenger receptor...)
(Previous symbol: API6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CD5 Molecule-Like1 2     AIM2
API61 2 3     PRO2292
Apoptosis Inhibitor 61 2     SP-ALPHA2
CD5 Antigen-Like (Scavenger Receptor Cysteine Rich Family)1 2     Spalpha2
IgM-Associated Peptide2 3     CD5 Antigen-Like2
CT-22 3     SP-alpha3

External Ids:    HGNC: 16901   Entrez Gene: 9222   Ensembl: ENSG000000737547   OMIM: 6025925   UniProtKB: O438663   

Export aliases for CD5L gene to outside databases

Previous GC identifers: GC01M155669 GC01M153577 GC01M154578 GC01M155017 GC01M155011 GC01M154613 GC01M156067 GC01M129158


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CD5L Gene: 
CD5L (CD5 molecule-like) is a protein-coding gene. Diseases associated with CD5L include wolman disease, and hereditary elliptocytosis. GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is LOXL2.

UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
Function: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of
apoptosis

Gene Wiki entry for CD5L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD5L gene promoter:
         Evi-1   RORalpha1   Max   PPAR-gamma1   FAC1   POU2F1   POU2F1a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD5L promoter sequence
   Search SABiosciences Chromatin IP Primers for CD5L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD5L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q23   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q21-q23

CD5L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD5L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M157800:  view genomic region     (about GC identifiers)

Start:
157,800,704 bp from pter      End:
157,868,046 bp from pter
Size:
67,343 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866 (See protein sequence)
Recommended Name: CD5 antigen-like precursor  
Size: 347 amino acids; 38088 Da
Subunit: Associated with IgM
Subcellular location: Secreted
Secondary accessions: A8K7M5 Q6UX63

Explore the universe of human proteins at neXtProt for CD5L: NX_O43866

Explore proteomics data for CD5L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43866

  • CD5L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CD5L Protein Expression
    REFSEQ proteins: NP_005885.1  
    ENSEMBL proteins: 
     ENSP00000357156  

    Human Recombinant Protein Products for CD5L: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CD5L
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CD5L
    OriGene Protein Over-expression Lysate for CD5L
    OriGene MassSpec for CD5L 
    OriGene Custom Protein Services for CD5L
    GenScript Custom Purified and Recombinant Proteins Services for CD5L
    Novus Biologicals CD5L Proteins
    Novus Biologicals CD5L Lysates
    Sino Biological Recombinant Protein for CD5L
    Sino Biological Cell Lysate for CD5L 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CD5L 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS14718574
    GO:0005615extracellular space TAS9045627
    GO:0016020membrane IEA--

    CD5L for ontologies           About GeneDecksing



    CD5L Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals CD5L Antibodies
    Abcam antibodies for CD5L
    Cloud-Clone Corp. Antibodies for CD5L 
    ThermoFisher Antibodies for CD5L
    LSBio Antibodies in human, mouse, rat for CD5L 

    Assay Products for CD5L: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CD5L
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CD5L
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CD5L 
    Cloud-Clone Corp. CLIAs for CD5L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001190 Srcr_rcpt
     IPR017448 Srcr_rcpt-rel

    Graphical View of Domain Structure for InterPro Entry O43866

    ProtoNet protein and cluster: O43866

    1 Blocks protein domain: IPB001190 Speract/scavenger receptor

    UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
    Similarity: Contains 3 SRCR domains


    CD5L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CD5L_HUMAN, O43866
    Function: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of
    apoptosis

         Genatlas biochemistry entry for CD5L:
    CD5 antigen-like secreted protein alpha,expressed in lymphoid tissues,potential regulator of monocyte
    activation,function and/or survival

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005044scavenger receptor activity IEA--
         
    CD5L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CD5L:
     High actin ratio cells 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cd5l):
     cellular  hematopoietic system  immune system 

    CD5L for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cd5ltm1Nto for CD5L

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CD5L 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD5L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD5L 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD5L 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD5L
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CD5L:
    hsa-miR-431
    SwitchGear 3'UTR luciferase reporter plasmidCD5L 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD5L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD5L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CD5L
    Sirion Biotech Customized adenovirus for overexpression of CD5L

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CD5L (see all 7)
    OriGene ORF clones in mouse, rat for CD5L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CD5L (NM_005894)
    Sino Biological Human cDNA Clone for CD5L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD5L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD5L
    Sirion Biotech Customized lentivirus for stable overexpression of CD5L 
                         Customized lentivirus expression plasmids for stable overexpression of CD5L 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CD5L
    Search LifeMap BioReagents cell lines for CD5L
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD5L


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CD5L

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for CD5L (O438662, 3 ENSP000003571564) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD40LGP299653, ENSP000003596634I2D: score=1 STRING: ENSP00000359663
    --P129782MINT-6770856
    --Q9WMX22MINT-7049231
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0006968cellular defense response TAS9045627

    CD5L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CD5L

    Search CenterWatch for drugs/clinical trials and news about CD5L

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CD5L gene: 
    NM_005894.2  

    Unigene Cluster for CD5L:

    CD5 molecule-like
    Hs.134035  [show with all ESTs]
    Unigene Representative Sequence: NM_005894
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368174(uc001frk.4) ENST00000484609
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD5L
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CD5L:
    hsa-miR-431
    SwitchGear 3'UTR luciferase reporter plasmidCD5L 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD5L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD5L
    Clone
    Products:
         
    OriGene clones in human, mouse for CD5L (see all 7)
    OriGene ORF clones in mouse, rat for CD5L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CD5L (NM_005894)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD5L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD5L
    Sirion Biotech Customized lentivirus for stable overexpression of CD5L 
                         Customized lentivirus expression plasmids for stable overexpression of CD5L 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CD5L
    OriGene qSTAR qPCR primer pairs in human, mouse for CD5L
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CD5L
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD5L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD5L

    Additional mRNA sequence: 

    AF011429.1 AF147312.1 AK292040.1 AY358494.1 BC033586.1 U82812.1 

    4 DOTS entries:

    DT.413443  DT.101979190  DT.121383479  DT.40207025 

    24/52 AceView cDNA sequences (see all 52):

    AF011429 BE384446 BE274956 BX094535 AI022195 N77007 AF147312 BQ024474 
    BC033586 AA341838 BX279835 BX371695 AA341837 AA694304 BQ711118 BM091582 
    NM_005894 BQ711375 BI768584 BI768208 N55522 CA309054 BM091287 AA677254 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CD5L expression in normal human tissues (normalized intensities)      CD5L embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGAAGACAC
    CD5L Expression
    About this image


    CD5L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Liver (Hepatobiliary System)
             Mature Mesothelial Cells Hepatic Mesenchyme
     
     Spleen (Hematopoietic System)

    See CD5L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CD5L

    SOURCE GeneReport for Unigene cluster: Hs.134035

    UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
    Tissue specificity: Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid
    tissues

        SABiosciences Custom PCR Arrays for CD5L
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CD5L
    OriGene qSTAR qPCR primer pairs in human, mouse for CD5L
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD5L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD5L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for CD5L gene from 1/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cd5l1 , 5 CD5 antigen-like1, 5 76.26(n)1
    70.06(a)1
      3 (38.19 cM)5
    118011  NM_009690.21  NP_033820.21 
     873578815 


    ENSEMBL Gene Tree for CD5L (if available)
    TreeFam Gene Tree for CD5L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CD5L gene
    LOXL22  CD62  CD163L12  LOXL42  CD1632  LOXL32  SSC5D2  PRSS122  
    LOX2  SRCRB4D2  LOXL12  DMBT12  
    6 SIMAP similar genes for CD5L using alignment to 1 protein entry:     CD5L_HUMAN:
    CD163    CD163L1    DMBT1    PRSS12    CD6    SSC5D

    CD5L for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CD5L
    PGOHUM00000245024


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/299 SNPs in CD5L are shown (see all 299)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1428350651,2
    C--157800334(+) CTGATG/TATTGA 1 -- ds50010--------
    rs1460833081,2
    --157800336(+) GATGAC/TTGAAC 1 -- ds50010--------
    rs1401372401,2
    --157800353(+) GACAGA/TATTAA 1 -- ds50010--------
    rs754429531,2
    F--157800561(+) TTGCAC/TACCCA 1 -- ds50011Minor allele frequency- T:0.04WA 118
    rs1146924071,2
    F--157800603(+) TGGAAG/AGTTCT 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs781738841,2
    C,F--157800640(+) TGCCAT/CAGAGA 1 -- ds50011Minor allele frequency- C:0.02NA 120
    rs1860308071,2
    --157800815(+) TCAAGG/TCTTGA 1 -- ut310--------
    rs1907976221,2
    --157800869(+) CTCAGC/TTGATA 1 -- ut310--------
    rs1819117601,2
    --157800885(+) AAAATG/TATATT 1 -- ut310--------
    rs1864453731,2
    --157800938(+) GATCTC/TTTTCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CD5L (157800704 - 157868046 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CD5L: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CD5L
    DNA2.0 Custom Variant and Variant Library Synthesis for CD5L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602592    OMIM disorders: --

    12 diseases for CD5L:    About MalaCards
    wolman disease    hereditary elliptocytosis    kawasaki disease    atopic dermatitis
    choroiditis    dermatitis    inflammatory bowel disease    hepatitis c
    hepatitis b    hepatitis    adenocarcinoma    alzheimer's disease

    1 disease from the University of Copenhagen DISEASES database for CD5L:
    Wolman disease

    CD5L for disorders           About GeneDecksing

    Genetic Association Database (GAD): CD5L
    Human Genome Epidemiology (HuGE) Navigator: CD5L (4 documents)

    Export disorders for CD5L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CD5L gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with CD5L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins. (PubMed id 9045627)1, 2, 3, 9 Gebe J.A.... Aruffo A. (1997)
    2. IgM are associated to Spalpha (CD5 antigen-like). (PubMed id 11981870)1, 2, 9 Tissot J.D.... Duchosal M.A. (2002)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1, 4 Chapuis J....Lambert J.C. (2009)
    5. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (2008)
    6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    10. Two-dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM-associated peptide. (PubMed id 8034987)1, 2 Tissot J.-D....Schneider P. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 922 HGNC: 1690 AceView: CD5L Ensembl:ENSG00000073754 euGenes: HUgn922
    ECgene: CD5L H-InvDB: CD5L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CD5L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CD5L gene:
    Search GeneIP for patents involving CD5L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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