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CD5L Gene

protein-coding   GIFtS: 58
GCID: GC01M157800

CD5 Molecule-Like

(Previous names: apoptosis inhibitor 6, CD5 antigen-like (scavenger receptor...)
(Previous symbol: API6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD5 Molecule-Like1 2     AIM2
API61 2 3     PRO2292
Apoptosis Inhibitor 61 2     SP-ALPHA2
CD5 Antigen-Like (Scavenger Receptor Cysteine Rich Family)1 2     Spalpha2
IgM-Associated Peptide2 3     CD5 Antigen-Like2
CT-22 3     SP-alpha3

External Ids:    HGNC: 16901   Entrez Gene: 9222   Ensembl: ENSG000000737547   OMIM: 6025925   UniProtKB: O438663   

Export aliases for CD5L gene to outside databases

Previous GC identifers: GC01M155669 GC01M153577 GC01M154578 GC01M155017 GC01M155011 GC01M154613 GC01M156067 GC01M129158


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CD5L Gene:
CD5L (CD5 molecule-like) is a protein-coding gene. Diseases associated with CD5L include wolman disease, and hereditary elliptocytosis. GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is LOXL2.

UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
Function: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of
apoptosis

Gene Wiki entry for CD5L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD5L gene promoter:
         Evi-1   RORalpha1   Max   PPAR-gamma1   FAC1   POU2F1   POU2F1a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD5L promoter sequence
   Search Chromatin IP Primers for CD5L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD5L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q23   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q21-q23

CD5L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD5L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M157800:  view genomic region     (about GC identifiers)

Start:
157,800,704 bp from pter      End:
157,868,046 bp from pter
Size:
67,343 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866 (See protein sequence)
Recommended Name: CD5 antigen-like precursor  
Size: 347 amino acids; 38088 Da
Subunit: Associated with IgM
Secondary accessions: A8K7M5 Q6UX63

Explore the universe of human proteins at neXtProt for CD5L: NX_O43866

Explore proteomics data for CD5L at MOPED


See CD5L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_005885.1  
ENSEMBL proteins: 
 ENSP00000357156  

CD5L Human Recombinant Protein Products:

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CD5L Assay Products:

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Cloud-Clone Corp. ELISAs for CD5L
Cloud-Clone Corp. CLIAs for CD5L


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR001190 SRCR
 IPR017448 Srcr_rcpt-rel

Graphical View of Domain Structure for InterPro Entry O43866

ProtoNet protein and cluster: O43866

1 Blocks protein domain: IPB001190 Speract/scavenger receptor

UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
Similarity: Contains 3 SRCR domains


CD5L for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CD5L_HUMAN, O43866
Function: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of
apoptosis

     Genatlas biochemistry entry for CD5L:
CD5 antigen-like secreted protein alpha,expressed in lymphoid tissues,potential regulator of monocyte
activation,function and/or survival

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005044scavenger receptor activity IEA--
     
CD5L for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for CD5L:
 High actin ratio cells 

     2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cd5l):
 hematopoietic system  immune system 

CD5L for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Cd5ltm1Nto for CD5L

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD5L
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CD5L

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD5L
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD5L

miRNA
Products:
    
miRTarBase miRNAs that target CD5L:
hsa-mir-335-5p (MIRT017271)

Block miRNA regulation of human, mouse, rat CD5L using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate CD5L:
hsa-miR-431
SwitchGear 3'UTR luciferase reporter plasmidCD5L 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CD5L
Predesigned siRNA for gene silencing in human, mouse, rat CD5L

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CD5L

Clone
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OriGene clones in human, mouse for CD5L (see all 6)
OriGene ORF clones in mouse, rat for CD5L
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CD5L (NM_005894)
Sino Biological Human cDNA Clone for CD5L
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD5L
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD5L

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD5L


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CD5L_HUMAN, O43866: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region NAS14718574
GO:0005615extracellular space TAS9045627
GO:0016020membrane IEA--
GO:0072562blood microparticle IDA--

CD5L for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CD5L
Interactions:

    Search GeneGlobe Interaction Network for CD5L

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

3 Interacting proteins for CD5L (O438662, 3 ENSP000003571564) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CD40LGP299653, ENSP000003596634I2D: score=1 STRING: ENSP00000359663
--P129782MINT-6770856
--Q9WMX22MINT-7049231
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006915apoptotic process IEA--
GO:0006968cellular defense response TAS9045627

CD5L for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CD5L



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CD5L gene: 
NM_005894.2  

Unigene Cluster for CD5L:

CD5 molecule-like
Hs.134035  [show with all ESTs]
Unigene Representative Sequence: NM_005894
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000368174(uc001frk.4) ENST00000484609
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CD5L using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate CD5L:
hsa-miR-431
SwitchGear 3'UTR luciferase reporter plasmidCD5L 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CD5L
Predesigned siRNA for gene silencing in human, mouse, rat CD5L
Clone
Products:
     
OriGene clones in human, mouse for CD5L (see all 6)
OriGene ORF clones in mouse, rat for CD5L
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CD5L (NM_005894)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD5L
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD5L
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CD5L
OriGene qSTAR qPCR primer pairs in human, mouse for CD5L
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD5L
  QuantiTect SYBR Green Assays in human, mouse, rat CD5L
  QuantiFast Probe-based Assays in human, mouse, rat CD5L

Additional mRNA sequence: 

AF011429.1 AF147312.1 AK292040.1 AY358494.1 BC033586.1 U82812.1 

4 DOTS entries:

DT.413443  DT.101979190  DT.121383479  DT.40207025 

Selected AceView cDNA sequences (see all 52):

BC033586 N77007 BX279835 AA341838 AF011429 BE274956 AI022195 BE384446 
BX094535 BQ024474 AF147312 CA309054 BX371695 BQ711483 BG745579 AY358494 
U82812 AA677254 AA694304 H91150 BM091582 BQ711375 NM_005894 AA341837 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CD5L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATGAAGACAC
CD5L Expression
About this image


CD5L expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Liver (Hepatobiliary System)
         Mature Mesothelial Cells Hepatic Mesenchyme
 
 Adipose (Muscoskeletal System)
         Visceral White Adipocytes Visceral White Adipose
 
 Spleen (Hematopoietic System)
CD5L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CD5L Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.134035

UniProtKB/Swiss-Prot: CD5L_HUMAN, O43866
Tissue specificity: Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid
tissues

    Custom PCR Arrays for CD5L
Primer
Products:
OriGene qPCR primer pairs and template standards for CD5L
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Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD5L
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QuantiFast Probe-based Assays in human, mouse, rat CD5L
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD5L

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CD5L gene from Selected species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cd5l1 , 5 CD5 antigen-like1, 5 76.07(n)1
70.06(a)1
  3 (38.19 cM)5
118011  NM_009690.21  NP_033820.21 
 873578815 
lizard
(Anolis carolinensis)
Reptilia CD5L6
CD5 molecule-like
10(a)
1 ↔ 1
GL343679.1(5220-13334)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-161n3.36
si:ch211-161n3.3
8(a)
many ↔ many
4(10023966-10037937) ENSDARG00000092989


ENSEMBL Gene Tree for CD5L (if available)
TreeFam Gene Tree for CD5L (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CD5L gene
LOXL22  CD62  CD163L12  LOXL42  CD1632  LOXL32  SSC5D2  PRSS122  
LOX2  SRCRB4D2  LOXL12  DMBT12  
6 SIMAP similar genes for CD5L using alignment to 1 protein entry:     CD5L_HUMAN:
CD163    CD163L1    DMBT1    PRSS12    CD6    SSC5D

CD5L for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for CD5L
PGOHUM00000245024


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CD5L (see all 299)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1428350651,2
C--157800334(+) CTGATG/TATTGA 1 -- ds50010--------
rs1460833081,2
--157800336(+) GATGAC/TTGAAC 1 -- ds50010--------
rs1401372401,2
--157800353(+) GACAGA/TATTAA 1 -- ds50010--------
rs754429531,2
F--157800561(+) TTGCAC/TACCCA 1 -- ds50011Minor allele frequency- T:0.04WA 118
rs1146924071,2
F--157800603(+) TGGAAG/AGTTCT 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs781738841,2
C,F--157800640(+) TGCCAT/CAGAGA 1 -- ds50011Minor allele frequency- C:0.02NA 120
rs1860308071,2
--157800815(+) TCAAGG/TCTTGA 1 -- ut310--------
rs1907976221,2
--157800869(+) CTCAGC/TTGATA 1 -- ut310--------
rs1819117601,2
--157800885(+) AAAATG/TATATT 1 -- ut310--------
rs1864453731,2
--157800938(+) GATCTC/TTTTCT 1 -- ut310--------

HapMap Linkage Disequilibrium report for CD5L (157800704 - 157868046 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for CD5L: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CD5L
DNA2.0 Custom Variant and Variant Library Synthesis for CD5L

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 602592    OMIM disorders: --

13 diseases for CD5L:    
About MalaCards
wolman disease    hereditary elliptocytosis    kawasaki disease    atopic dermatitis
choroiditis    dermatitis    inflammatory bowel disease    hepatitis c
hepatitis    hepatitis b    alzheimer's disease    hiv-1
adenocarcinoma

1 disease from the University of Copenhagen DISEASES database for CD5L:
Wolman disease

CD5L for disorders           About GeneDecksing

Genetic Association Database (GAD): CD5L
Human Genome Epidemiology (HuGE) Navigator: CD5L (4 documents)

Export disorders for CD5L gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CD5L gene, integrated from 10 sources (see all 29):
(articles sorted by number of sources associating them with CD5L)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins. (PubMed id 9045627)1, 2, 3, 9 Gebe J.A.... Aruffo A. (J. Biol. Chem. 1997)
  2. IgM are associated to Spalpha (CD5 antigen-like). (PubMed id 11981870)1, 2, 9 Tissot J.D.... Duchosal M.A. (Electrophoresis 2002)
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  4. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1, 4 Chapuis J....Lambert J.C. (Mol. Psychiatry 2009)
  5. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (J. Lipid Res. 2008)
  6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
  9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  10. Two-dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM-associated peptide. (PubMed id 8034987)1, 2 Tissot J.-D....Schneider P. (J. Immunol. Methods 1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 922 HGNC: 1690 AceView: CD5L Ensembl:ENSG00000073754 euGenes: HUgn922
ECgene: CD5L H-InvDB: CD5L

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CD5L Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CD5L gene:
Search GeneIP for patents involving CD5L

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
 Antibodies for CD5L (CD5L)   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Recombinant/Natural Proteins for CD5L (CD5L)   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for CD5L   OriGene RNAi products in human, mouse, rat for CD5L  
 OriGene qPCR primer pairs and template standards for CD5L   OriGene Protein Over-expression Lysate for CD5L  
 OriGene MassSpec something-or-other for CD5L   OriGene clones in human, mouse for CD5L  
 OriGene qSTAR qPCR primer pairs in human, mouse for CD5L   OriGene Purified Protein for CD5L  
 OriGene ORF clones in mouse, rat for CD5L   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CD5L   OriGene Custom Protein Services for CD5L  

 
 
 Block miRNA regulation of human, mouse, rat CD5L using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CD5L
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD5L Predesigned siRNA for gene silencing in human, mouse, rat CD5L
 QuantiFast Probe-based Assays in human, mouse, rat CD5L QuantiTect SYBR Green Assays in human, mouse, rat CD5L
 Custom PCR Arrays for CD5L Search Chromatin IP Primers for CD5L
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD5L  Search GeneGlobe Interaction Network for CD5L
 Regulatory tfbs in CD5L promoter
 GenScript Custom Purified and Recombinant Proteins Services for CD5L GenScript cDNA clones with any tag delivered in your preferred vector for CD5L
 GenScript Custom Assay Services for CD5L GenScript Custom overexpressing Cell Line Services for CD5L
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for CD5L
 Proteins for CD5L
 Cell Lysates for CD5L
 cDNA Clones for CD5L
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 CD5L antibodies
 CD5L proteins
 CD5L lysates
 Antibodies for CD5L
 See all of Abcam's Antibodies, Kits and Proteins for CD5L
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for CD5L
 Antibodies for CD5L
 ELISAs for CD5L
 CLIAs for CD5L



 Browse ESI BIO Cell Lines and PureStem Progenitors for CD5L
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD5L
 SwitchGear 3'UTR luciferase reporter plasmids for CD5L
 SwitchGear Promoter luciferase reporter plasmids for CD5L
 ThermoFisher Antibodies for CD5L
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD5L
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD5L
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CD5L
 LSBio Antibodies in human, mouse, rat for CD5L
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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