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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CD52 Gene

protein-coding   GIFtS: 51
GCID: GC01P026644

CD52 Molecule

(Previous name: CD52 antigen (CAMPATH-1 antigen))
(Previous symbol: CDW52)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CD52 Molecule1 2     CDW52 Antigen (CAMPATH-1 Antigen)2
CDW521 2 3     he52
CD52 Antigen (CAMPATH-1 Antigen)1 2     CDw523
Cambridge Pathology 1 Antigen2 3     HE53
Epididymal Secretory Protein E52 3     He53
Human Epididymis-Specific Protein 52 3     CD52 Antigen3
CAMPATH-1 Antigen2     

External Ids:    HGNC: 18041   Entrez Gene: 10432   Ensembl: ENSG000001694427   OMIM: 1142805   UniProtKB: P313583   

Export aliases for CD52 gene to outside databases

Previous GC identifers: GC01P026329 GC01P026516 GC01P024898


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CD52 Gene: 
CD52 (CD52 molecule) is a protein-coding gene. Diseases associated with CD52 include epididymitis, and paroxysmal nocturnal hemoglobinuria.

UniProtKB/Swiss-Prot: CD52_HUMAN, P31358
Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD52 gene promoter:
         GR   COUP-TF1   COUP   HNF-4alpha2   Evi-1   HNF-4alpha1   COUP-TF   GR-alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD52 promoter sequence
   Search SABiosciences Chromatin IP Primers for CD52

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD52


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36

CD52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD52 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P026644:  view genomic region     (about GC identifiers)

Start:
26,644,411 bp from pter      End:
26,647,014 bp from pter
Size:
2,604 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CD52_HUMAN, P31358 (See protein sequence)
Recommended Name: CAMPATH-1 antigen precursor  
Size: 61 amino acids; 6614 Da
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Secondary accessions: Q5T138 Q9BW46

Explore the universe of human proteins at neXtProt for CD52: NX_P31358

CD52 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

REFSEQ proteins: NP_001794.2  
ENSEMBL proteins: 
 ENSP00000363330  

Human Recombinant Protein Products for CD52: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for CD52
OriGene Protein Over-expression Lysate for CD52
OriGene Custom MassSpec 
OriGene Custom Protein Services for CD52
GenScript Custom Purified and Recombinant Proteins Services for CD52
Novus Biologicals CD52 Lysate
Sino Biological Recombinant Protein for CD52
Sino Biological Cell Lysate for CD52 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for CD52 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005887integral to plasma membrane TAS1711975
GO:0016020membrane TAS1711975
GO:0031225anchored to membrane IEA--

CD52 for ontologies           About GeneDecksing



CD52 Antibody Products: 
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OriGene Antibodies for CD52
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Novus Biologicals CD52 Antibodies
Abcam antibodies for CD52
Cloud-Clone Corp. Antibodies for CD52 
ThermoFisher Antibodies for CD52
LSBio Antibodies in human, mouse, rat for CD52 

Assay Products for CD52: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for CD52
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CD52
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for CD52 
Cloud-Clone Corp. CLIAs for CD52


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
CD: CD molecules

1 InterPro protein domain:
 IPR026643 CAMPATH-1

Graphical View of Domain Structure for InterPro Entry P31358

ProtoNet protein and cluster: P31358


CD52 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CD52_HUMAN, P31358
Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role

Phenotypes:
     1 GenomeRNAi human phenotype for CD52:

 Decreased number of cells in m 

     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Cd52):
 normal 

CD52 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Cd52tm1Osb for CD52

   inGenious Targeting Laboratory - Custom generated mouse model solutions for CD52 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD52

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD52 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD52 

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD52
1 QIAGEN miScript miRNA Assays for microRNA that regulate CD52:
hsa-miR-1207-3p
SwitchGear 3'UTR luciferase reporter plasmidCD52 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for CD52
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD52

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CD52
Sirion Biotech Customized adenovirus for overexpression of CD52

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for CD52 (see all 7)
OriGene ORF clones in mouse, rat for CD52
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
Sino Biological Human cDNA Clone for CD52
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD52
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52
Sirion Biotech Customized lentivirus for stable overexpression of CD52 
                     Customized lentivirus expression plasmids for stable overexpression of CD52 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CD52
Search LifeMap BioReagents cell lines for CD52
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD52


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section




Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CD52

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007204elevation of cytosolic calcium ion concentration IDA8223854
GO:0045730respiratory burst NAS8223854

CD52 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CD52 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CD52

1 DrugBank Compound for CD52    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
Alemtuzumab-- 216503-57-0targetantibody10573085 10092828 11752352 10520035 10744652 10366506 19343298 19479612

5 Novoseek inferred chemical compound relationships for CD52 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
alemtuzumab 95.3 55 11999566 (2), 16728276 (2), 7718516 (1), 14635201 (1) (see all 40)
fludarabine 68.4 1 15325705 (1)
rituximab 63 6 15737872 (1), 14962245 (1), 16615876 (1), 15101704 (1)
sialic acid 15.5 1 11420384 (1)
polysaccharide 0 1 9148769 (1)

Search CenterWatch for drugs/clinical trials and news about CD52

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CD52 gene: 
NM_001803.2  

Unigene Cluster for CD52:

CD52 molecule
Hs.276770  [show with all ESTs]
Unigene Representative Sequence: BQ276596
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000374213(uc001bmc.3) ENST00000492808(uc009vsg.1) ENST00000470468

miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD52
1 QIAGEN miScript miRNA Assays for microRNA that regulate CD52:
hsa-miR-1207-3p
SwitchGear 3'UTR luciferase reporter plasmidCD52 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for CD52
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD52
Clone
Products:
     
OriGene clones in human, mouse for CD52 (see all 7)
OriGene ORF clones in mouse, rat for CD52
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD52
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52
Sirion Biotech Customized lentivirus for stable overexpression of CD52 
                     Customized lentivirus expression plasmids for stable overexpression of CD52 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CD52
OriGene qSTAR qPCR primer pairs in human, mouse for CD52
SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD52
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD52
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD52

Additional mRNA sequence: 

AK311554.1 BC000644.2 BT007116.1 CR456874.1 X62466.1 X67699.1 

13 DOTS entries:

DT.100684959  DT.418763  DT.121392224  DT.100813681  DT.100813686  DT.100813685  DT.121392215  DT.121392198 
DT.100813682  DT.121392240  DT.121392272  DT.95349573  DT.100887414 

24/133 AceView cDNA sequences (see all 133):

CR616675 F23564 AA352719 BG535652 AA352820 X62466 BM919818 AL552682 
AV714491 CR607239 AI148019 AL553529 BM727211 AA393138 AI081982 BE675834 
AI142305 AA335891 AA435559 N90866 BM919108 BE268017 BU740772 BV200703 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CD52    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
SP1:                          -               
SP2:                    -     -               
SP3:                                          


ECgene alternative splicing isoforms for CD52

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CD52 expression in normal human tissues (normalized intensities)      CD52 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGGGCAACAG
CD52 Expression
About this image


CD52 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/11 selected tissues (see all 11) fully expand
 
 Blood (Hematopoietic System)    fully expand to see all 13 entries
         Double Positive Thymocytes Thymus
         Peripheral blood Pan-T Cells   
 
 Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 4 entries
         Cord Blood Pan-T Cells   
 
 Thymus (Hematopoietic System)    fully expand to see all 3 entries
         Double Positive Thymocytes Thymus
         Thymus
         Thymus   
 
 Neural Crest (Gastrulation Derivatives)
         mesenchyme   
 
 Mesoderm (Gastrulation Derivatives)
         mesenchyme   

Genevestigator expression for CD52

SOURCE GeneReport for Unigene cluster: Hs.276770
    SABiosciences Custom PCR Arrays for CD52
Primer
Products:
OriGene qPCR primer pairs and template standards for CD52
OriGene qSTAR qPCR primer pairs in human, mouse for CD52
SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD52
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD52
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD52
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD52

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for CD52 gene from 1/3 species (see all 3)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cd525 CD52 antigen   --   4 (66.50 cM) 134082448 


ENSEMBL Gene Tree for CD52 (if available)
TreeFam Gene Tree for CD52 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CD52 gene
1 SIMAP similar gene for CD52 using alignment to 2 protein entries:     CD52_HUMAN (see all proteins):
CDW52

CD52 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/14 SNPs in CD52 are shown (see all 14)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0507754
----see VAR_0507752 N S mis40--------
VAR_0148384
----see VAR_0148382 I M mis40--------
rs412854291,2
C--26646783(+) CTTCTG/ACTTCA 2 /Y /C mis11Minor allele frequency- A:0.00NA 4552
rs1164806821,2
C,F--26646911(+) AGAAGT/CTGACA 1 -- ut311Minor allele frequency- C:0.03WA 118
rs1827609171,2
--26646947(+) AAATAA/GGGGGG 1 -- ut310--------
rs1139458111,2
C--26647015(+) TTGCAA/GTGGGG 1 -- spd10--------
rs1156426261,2
F--26647022(+) GGGGTC/GCTGCT 1 -- int11Minor allele frequency- G:0.03WA 118
rs1440893611,2
--26647169(+) GCCCTC/TCCCCT 1 -- int10--------
rs1482420081,2
--26647225(+) CAACCC/TTGCAG 1 -- int10--------
rs1413754931,2
C--26647321(+) CCCTAC/TCCCAC 1 -- int10--------

HapMap Linkage Disequilibrium report for CD52 (26644411 - 26647014 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for CD52: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing CD52
DNA2.0 Custom Variant and Variant Library Synthesis for CD52

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 114280    OMIM disorders: --

20/33 diseases for CD52 (see all 33):    About MalaCards
epididymitis    paroxysmal nocturnal hemoglobinuria    autoimmune hemolytic anemia    hairy cell leukemia
relapsing-remitting multiple sclerosis    macroglobulinemia    prolymphocytic leukemia    t-cell prolymphocytic leukemia
waldenstrom macroglobulinemia    hemoglobinuria    large granular lymphocyte leukemia    b-cell chronic lymphocytic leukemia
demyelinating polyneuropathy    aplastic anemia    mantle cell lymphoma    hemolytic anemia
chronic lymphocytic leukemia    polyneuropathy    leukopenia    multiple sclerosis

3 diseases from the University of Copenhagen DISEASES database for CD52:
Leukemia     Lymphoma     Leukopenia

CD52 for disorders           About GeneDecksing

10/11 Novoseek inferred disease relationships for CD52 gene (see all 11)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cll refractory 73.4 1 15325705 (1)
leukemia lymphocytic chronic 68.2 4 11999566 (1), 17624249 (1), 17960607 (1), 19642457 (1)
lymphoproliferative disorders 57.3 3 11999566 (1), 17624249 (1), 17428002 (1), 16371014 (1)
leukaemia lymphocytic 50.7 2 16371014 (1), 11792397 (1)
lymphoma t-cell 39.7 1 16371014 (1)
lymphoma non-hodgkins 37.2 3 11807632 (1), 9126378 (1), 8027367 (1)
lymphoma 24 3 11999566 (1), 10524207 (1)
autoimmune diseases 21 1 11792397 (1)
multiple sclerosis 15.4 2 8624684 (1), 9345418 (1)
rheumatoid arthritis 15.3 3 7718516 (1), 8707338 (1), 9126378 (1)

Human Genome Epidemiology (HuGE) Navigator: CD52 (1 document)

Export disorders for CD52 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CD52 gene, integrated from 9 sources (see all 115):
(articles sorted by number of sources associating them with CD52)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. (PubMed id 1711975)1, 2, 3 Xia M.-Q.... Waldmann H. (1991)
  2. A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone. (PubMed id 8418821)1, 2, 9 Kirchhoff C.... Ivell R. (1993)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol- anchored glycoprotein which is an exceptionally good target for complement lysis. (PubMed id 7688956)1, 2 Xia M.Q.... Waldmann H. (1993)
  5. Different levels of CD52 antigen expression evaluated by quantitative fluorescence cytometry are detected on B-lymphocytes, CD 34+ cells and tumor cells of patients with chronic B-cell lymphoproliferative diseases. (PubMed id 17428002)1, 9 Klabusay M....Mayer J. (2007)
  6. Structure and chromosomal location of mouse and human CD52 genes. (PubMed id 10524207)1, 9 Tone M.... Waldmann H. (1999)
  7. Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. (PubMed id 7718516)1, 9 Rowan W.C....Brett S.J. (1995)
  8. Surface and mRNA expression of the CD52 antigen by human eosinophils but not by neutrophils. (PubMed id 8977262)1, 9 Elsner J....Kapp A. (1996)
  9. The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen. (PubMed id 17624925)1, 9 Flori F....Giovampaola C.D. (2008)
  10. CD52 antigen--a review. (PubMed id 11257744)1, 9 Domagal/a A. and Kurpisz M. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 1043 HGNC: 1804 AceView: CDW52 Ensembl:ENSG00000169442 euGenes: HUgn1043
ECgene: CD52 H-InvDB: CD52

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for CD52 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CD52 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for CD52 gene:
Search GeneIP for patents involving CD52

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore Custom Antibody & Bulk Services
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 OriGene Antibodies for CD52   OriGene RNAi products in human, mouse, rat for CD52  
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 OriGene Custom Antibody Services for CD52   OriGene Custom Protein Services for CD52  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CD52
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 Regulatory tfbs in CD52 promoter
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 See all of Abcam's Antibodies, Kits and Proteins for CD52
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 Proteins for CD52
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 Gene Synthesis
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 inGenious Targeting Laboratory - Custom generated mouse model solutions for CD52
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD52
Customized:
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Customized transgenic rodents for:
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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