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CD52 Gene

protein-coding   GIFtS: 51
GCID: GC01P026644

CD52 Molecule

(Previous name: CD52 antigen (CAMPATH-1 antigen))
(Previous symbol: CDW52)
  See CD52-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD52 Molecule1 2     CDW52 Antigen (CAMPATH-1 Antigen)2
CDW521 2 3 5     Epididymis Secretory Sperm Binding Protein Li 171mP2
CD52 Antigen (CAMPATH-1 Antigen)1 2     he52
Cambridge Pathology 1 Antigen2 3     CDw523
Epididymal Secretory Protein E52 3     HE53
Human Epididymis-Specific Protein 52 3     He53
HEL-S-171mP2     CD52 Antigen3
CAMPATH-1 Antigen2     

External Ids:    HGNC: 18041   Entrez Gene: 10432   Ensembl: ENSG000001694427   OMIM: 1142805   UniProtKB: P313583   

Export aliases for CD52 gene to outside databases

Previous GC identifers: GC01P026329 GC01P026516 GC01P024898


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CD52 Gene:
CD52 (CD52 molecule) is a protein-coding gene. Diseases associated with CD52 include t-cell prolymphocytic leukemia, and hairy cell leukemia.

UniProtKB/Swiss-Prot: CD52_HUMAN, P31358
Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD52 gene promoter:
         GR   COUP-TF1   COUP   HNF-4alpha2   Evi-1   HNF-4alpha1   COUP-TF   GR-alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD52 promoter sequence
   Search Chromatin IP Primers for CD52

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD52


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36

CD52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD52 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P026644:  view genomic region     (about GC identifiers)

Start:
26,644,411 bp from pter      End:
26,647,014 bp from pter
Size:
2,604 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CD52_HUMAN, P31358 (See protein sequence)
Recommended Name: CAMPATH-1 antigen precursor  
Size: 61 amino acids; 6614 Da
Secondary accessions: Q5T138 Q9BW46

Explore the universe of human proteins at neXtProt for CD52: NX_P31358

Post-translational modifications: 

  • Glycosylation2 at Asn27, Asn40
  • REFSEQ proteins: NP_001794.2  
    ENSEMBL proteins: 
     ENSP00000363330  

    CD52 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CD52

     
    Search eBioscience for Proteins for CD52 

     
    Search antibodies-online for proteins for CD52 

     
    Search antibodies-online for peptides for CD52

    CD52 Antibody Products:

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    antibodies-online antibodies for CD52 (62 products) 

    CD52 Assay Products:

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    Cloud-Clone Corp. ELISAs for CD52
    Cloud-Clone Corp. CLIAs for CD52
    Search eBioscience for ELISAs for CD52 
    antibodies-online kits for CD52 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules

    1 InterPro protein domain:
     IPR026643 CAMPATH-1

    Graphical View of Domain Structure for InterPro Entry P31358

    ProtoNet protein and cluster: P31358


    Find genes that share domains with CD52           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CD52_HUMAN, P31358
    Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role

    Phenotypes:
         1 GenomeRNAi human phenotype for CD52:

     Decreased number of cells in m 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Cd52):
     normal 

    Find genes that share phenotypes with CD52           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cd52tm1Osb for CD52

       genOway: Develop your customized and physiologically relevant rodent model for CD52

    miRNA
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    Block miRNA regulation of human, mouse, rat CD52 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CD52:
    hsa-miR-1207-3p
    SwitchGear 3'UTR luciferase reporter plasmidCD52 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CD52
    Predesigned siRNA for gene silencing in human, mouse, rat CD52

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for CD52
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    GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
    Sino Biological Human cDNA Clone for CD52
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD52
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD52


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CD52_HUMAN, P31358: Cell membrane; Lipid-anchor, GPI-anchor
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    endoplasmic reticulum1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral component of plasma membrane TAS1711975
    GO:0016020membrane TAS1711975
    GO:0031225anchored component of membrane IEA--

    Find genes that share ontologies with CD52           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CD52
    Interactions:

        GeneGlobe Interaction Network for CD52

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007204positive regulation of cytosolic calcium ion concentration IDA8223854
    GO:0045730respiratory burst NAS8223854

    Find genes that share ontologies with CD52           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CD52

    1 DrugBank Compound for CD52    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Alemtuzumab-- 216503-57-0targetantibody10573085 10092828 11752352 10520035 10744652 10366506 19343298 19479612

    5 Novoseek inferred chemical compound relationships for CD52 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alemtuzumab 95.3 55 11999566 (2), 16728276 (2), 7718516 (1), 14635201 (1) (see all 40)
    fludarabine 68.4 1 15325705 (1)
    rituximab 63 6 15737872 (1), 14962245 (1), 16615876 (1), 15101704 (1)
    sialic acid 15.5 1 11420384 (1)
    polysaccharide 0 1 9148769 (1)



    Find genes that share compounds with CD52           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CD52 gene: 
    NM_001803.2  

    Unigene Cluster for CD52:

    CD52 molecule
    Hs.276770  [show with all ESTs]
    Unigene Representative Sequence: BQ276596
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374213(uc001bmc.3) ENST00000492808(uc009vsg.1) ENST00000470468

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate CD52:
    hsa-miR-1207-3p
    SwitchGear 3'UTR luciferase reporter plasmidCD52 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CD52
    Predesigned siRNA for gene silencing in human, mouse, rat CD52
    Clone
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    GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52
    Primer
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    OriGene qPCR primer pairs and template standards for CD52
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CD52
      QuantiTect SYBR Green Assays in human, mouse, rat CD52
      QuantiFast Probe-based Assays in human, mouse, rat CD52

    Additional mRNA sequence: 

    AK311554.1 BC000644.2 BT007116.1 CR456874.1 X62466.1 X67699.1 

    13 DOTS entries:

    DT.100684959  DT.418763  DT.121392224  DT.100813681  DT.100813686  DT.100813685  DT.121392215  DT.121392198 
    DT.100813682  DT.121392240  DT.121392272  DT.95349573  DT.100887414 

    Selected AceView cDNA sequences (see all 133):

    AA352820 X62466 CR607239 CR616675 BG535652 F23564 AI148019 BM919818 
    AL552682 AL553529 AV714491 AA352719 AW338974 BU564758 BM422397 N90866 
    AI718589 BE268017 AA435559 AA654602 BE675834 AI880649 AA335375 BV200703 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CD52    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
    SP1:                          -               
    SP2:                    -     -               
    SP3:                                          


    ECgene alternative splicing isoforms for CD52

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CD52 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGGCAACAG
    CD52 Expression
    About this image


    CD52 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             Double Positive Thymocytes Thymus
             Thymus
     
     Adipose (Muscoskeletal System)
             Body Subcutaneous White Adipose
     
     Blood (Cardiovascular System)
             Double Positive Thymocytes Thymus
     
     Lung (Respiratory System)
     
     Tonsil (Hematopoietic System)
    CD52 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.276770
        Custom PCR Arrays for CD52
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD52

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CD52 gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cd525 CD52 antigen   --   4 (66.50 cM) 134082448 


    ENSEMBL Gene Tree for CD52 (if available)
    TreeFam Gene Tree for CD52 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CD52 gene
    1 SIMAP similar gene for CD52 using alignment to 2 protein entries:     CD52_HUMAN (see all proteins):
    CDW52

    Find genes that share paralogs with CD52           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CD52 (see all 14)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs412854291,2
    C--26646783(+) CTTCTG/ACTTCA 2 /Y /C mis11Minor allele frequency- A:0.00NA 4552
    rs1164806821,2
    C,F--26646911(+) AGAAGT/CTGACA 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs1827609171,2
    --26646947(+) AAATAA/GGGGGG 1 -- ut310--------
    rs1139458111,2
    C--26647015(+) TTGCAA/GTGGGG 1 -- spd10--------
    rs1156426261,2
    F--26647022(+) GGGGTC/GCTGCT 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1440893611,2
    --26647169(+) GCCCTC/TCCCCT 1 -- int10--------
    rs1482420081,2
    --26647225(+) CAACCC/TTGCAG 1 -- int10--------
    rs1413754931,2
    C--26647321(+) CCCTAC/TCCCAC 1 -- int10--------
    rs1878366741,2
    C--26647470(+) TCCCAC/TGCTGG 1 -- int10--------
    rs10718491,2,4
    ----see VAR_0507752 mis40--------

    HapMap Linkage Disequilibrium report for CD52 (26644411 - 26647014 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CD52: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CD52
    DNA2.0 Custom Variant and Variant Library Synthesis for CD52

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 114280    OMIM disorders: --

    7 diseases for CD52:    
    About MalaCards
    t-cell prolymphocytic leukemia    hairy cell leukemia    aplastic anemia    mantle cell lymphoma
    chronic lymphocytic leukemia    b-cell chronic lymphocytic leukemia    chronic myeloid leukemia

    3 diseases from the University of Copenhagen DISEASES database for CD52:
    Leukemia     Lymphoma     Leukopenia

    Find genes that share disorders with CD52           About GenesLikeMe

    Selected Novoseek inferred disease relationships for CD52 gene (see all 11)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cll refractory 73.4 1 15325705 (1)
    leukemia lymphocytic chronic 68.2 4 11999566 (1), 17624249 (1), 17960607 (1), 19642457 (1)
    lymphoproliferative disorders 57.3 3 11999566 (1), 17624249 (1), 17428002 (1), 16371014 (1)
    leukaemia lymphocytic 50.7 2 16371014 (1), 11792397 (1)
    lymphoma t-cell 39.7 1 16371014 (1)
    lymphoma non-hodgkins 37.2 3 11807632 (1), 9126378 (1), 8027367 (1)
    lymphoma 24 3 11999566 (1), 10524207 (1)
    autoimmune diseases 21 1 11792397 (1)
    multiple sclerosis 15.4 2 8624684 (1), 9345418 (1)
    rheumatoid arthritis 15.3 3 7718516 (1), 8707338 (1), 9126378 (1)

    Human Genome Epidemiology (HuGE) Navigator: CD52 (1 document)

    Export disorders for CD52 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CD52 gene, integrated from 10 sources (see all 115):
    (articles sorted by number of sources associating them with CD52)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. (PubMed id 1711975)1, 2, 3 Xia M.-Q.... Waldmann H. (Eur. J. Immunol. 1991)
    2. A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone. (PubMed id 8418821)1, 2, 9 Kirchhoff C.... Ivell R. (Mol. Reprod. Dev. 1993)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol- anchored glycoprotein which is an exceptionally good target for complement lysis. (PubMed id 7688956)1, 2 Xia M.Q.... Waldmann H. (Biochem. J. 1993)
    5. Different levels of CD52 antigen expression evaluated by quantitative fluorescence cytometry are detected on B-lymphocytes, CD 34+ cells and tumor cells of patients with chronic B-cell lymphoproliferative diseases. (PubMed id 17428002)1, 9 Klabusay M....Mayer J. (Cytometry B Clin Cytom 2007)
    6. Structure and chromosomal location of mouse and human CD52 genes. (PubMed id 10524207)1, 9 Tone M.... Waldmann H. (Biochim. Biophys. Acta 1999)
    7. Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. (PubMed id 7718516)1, 9 Rowan W.C....Brett S.J. (Int. Immunol. 1995)
    8. Surface and mRNA expression of the CD52 antigen by human eosinophils but not by neutrophils. (PubMed id 8977262)1, 9 Elsner J....Kapp A. (Blood 1996)
    9. The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen. (PubMed id 17624925)1, 9 Flori F....Giovampaola C.D. (Mol. Reprod. Dev. 2008)
    10. CD52 antigen--a review. (PubMed id 11257744)1, 9 DomagaA8a A. and Kurpisz M. (Med. Sci. Monit. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1043 HGNC: 1804 AceView: CDW52 Ensembl:ENSG00000169442 euGenes: HUgn1043
    ECgene: CD52 H-InvDB: CD52

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CD52 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CD52 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CD52 gene:
    Search GeneIP for patents involving CD52

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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