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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CD52 Gene

protein-coding   GIFtS: 49
GCID: GC01P026644

CD52 molecule

(Previous name: CD52 antigen (CAMPATH-1 antigen) )
(Previous symbol: CDW52)
 Explore 33 diseases affiliated with
CD52 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CD52    

Aliases
for CD52 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
CD52 Molecule1 2     CDW52 Antigen (CAMPATH-1 Antigen)2
CDW521 2 3     He53
CD52 Antigen (CAMPATH-1 Antigen)1 2     CDw523
Cambridge Pathology 1 Antigen2 3     HE53
Epididymal Secretory Protein E52 3     He53
Human Epididymis-Specific Protein 52 3     CD52 Antigen3
CAMPATH-1 Antigen2     

External Ids:    HGNC: 18041   Entrez Gene: 10432   Ensembl: ENSG000001694427   OMIM: 1142805   UniProtKB: P313583   

Export aliases for CD52 gene to outside databases

Previous GC identifers: GC01P026329 GC01P026516 GC01P024898


Summaries
for CD52 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: CD52_HUMAN, P31358
Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role




Genomic Views
for CD52 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD52 gene promoter:
         GR   COUP-TF1   COUP   HNF-4alpha2   Evi-1   HNF-4alpha1   COUP-TF   GR-alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CD52 promoter sequence
   Search SABiosciences Chromatin IP Primers for CD52

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD52


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36

CD52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD52 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P026644:  view genomic region     (about GC identifiers)

Start:
 26,644,411 bp from pter      End:
 26,647,014 bp from pter
Size:
 2,604 bases      Orientation:
 plus strand

Proteins
for CD52 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CD52_HUMAN, P31358 (See protein sequence)
Recommended Name: CAMPATH-1 antigen precursor  
Size: 61 amino acids; 6614 Da
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Secondary accessions: Q5T138 Q9BW46

Explore the universe of human proteins at neXtProt for CD52: NX_P31358

CD52 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_001794.2  
ENSEMBL proteins: 
 ENSP00000363330  

Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: CD52
OriGene Protein Over-expression Lysate: CD52
OriGene Custom Protein Services for CD52 
GenScript Custom Purified and Recombinant Proteins Services for CD52
Novus Biologicals CD52 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for CD52

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005624membrane fraction ----
GO:0005887integral to plasma membrane TAS1711975
GO:0016020membrane TAS1711975
GO:0031225anchored to membrane IEA--


CD52 for ontologies           About GeneDecksing



CD52 Antibody Products: 
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OriGene Antibodies: CD52
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Novus Biologicals CD52 Antibody
Search for Antibodies for CD52 at Abcam  
Uscn Antibodies for CD52
ThermoFisher Antibodies for CD52

Assay Products for CD52: 
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OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
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GenScript Custom Assay Services for CD52
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for CD52

Protein Domains /
Families
for CD52 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
CD52 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR026643 CAMPATH-1

Graphical View of Domain Structure for InterPro Entry P31358

ProtoNet protein and cluster: P31358


Function
for CD52 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:

     UniProtKB/Swiss-Prot: CD52_HUMAN, P31358
Function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role

miRNA
Products:    		 OriGene 3'-UTR Clone: CD52
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD52
1 QIAGEN miScript miRNA Assays for microRNA that regulate CD52:
hsa-miR-1207-3p
SwitchGear 3'UTR luciferase reporter plasmid: CD52 3' UTR sequence
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CD52 (see all 7)
OriGene shRNA RFP: CD52
OriGene siRNA: CD52
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD52

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for CD52

Clone
Products:     		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD52 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD52
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD52
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for CD52
Search LifeMap BioReagents cell lines for CD52

In Situ Assay
Products:   
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CD52

1 GenomeRNAi human phenotype for CD52:
 Decreased number of cells in m 

Animal Models:
     Mouse knock-out Cd52tm1Osb for CD52
     1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Cd52):
 normal 

CD52 for phenotypes           About GeneDecksing


Pathways & Interactions
for CD52 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CD52

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007204elevation of cytosolic calcium ion concentration IDA8223854
GO:0045730respiratory burst NAS8223854


CD52 for ontologies           About GeneDecksing



Drugs & Compounds
for CD52 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CD52 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CD52

1 DrugBank Compound for CD52    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
Alemtuzumab-- 216503-57-0targetantibody10573085 10092828 11752352 10520035 10744652 10366506 19343298 19479612

5 Novoseek chemical compound relationships for CD52 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
alemtuzumab 95.3 55 11999566 (2), 16728276 (2), 7718516 (1), 14635201 (1) (see all 40)
fludarabine 68.4 1 15325705 (1)
rituximab 63 6 15737872 (1), 14962245 (1), 16615876 (1), 15101704 (1)
sialic acid 15.5 1 11420384 (1)
polysaccharide 0 1 9148769 (1)

Search CenterWatch for drugs/clinical trials and news about CD52 

Transcripts
for CD52 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for CD52 gene: 
NM_001803.2  

Unigene Cluster for CD52:

CD52 molecule
Hs.276770  [show with all ESTs]
Unigene Representative Sequence: BQ276596
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000374213(uc001bmc.3) ENST00000492808(uc009vsg.1) ENST00000470468


miRNA
Products:     		 OriGene 3'-UTR Clone: CD52
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD52
1 QIAGEN miScript miRNA Assays for microRNA that regulate CD52:
hsa-miR-1207-3p
SwitchGear 3'UTR luciferase reporter plasmid: CD52 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CD52 (see all 7)
OriGene shRNA RFP: CD52
OriGene siRNA: CD52
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD52
Clone
Products:     		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD52 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD52
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CD52 (NM_001803)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD52
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52 
Primer
Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD52
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD52
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD52
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD52

Additional cDNA sequence: 

AK311554.1 BC000644.2 BT007116.1 CR456874.1 X62466.1 X67699.1 

13 DOTS entries:

DT.100684959  DT.418763  DT.121392224  DT.100813681  DT.100813686  DT.100813685  DT.121392215  DT.121392198 
DT.100813682  DT.121392240  DT.121392272  DT.95349573  DT.100887414 

24/133 AceView cDNA sequences (see all 133):

AA352820 BG535652 X62466 AL553529 CR616675 AA352719 BM919818 AV714491 
AI148019 CR607239 F23564 AL552682 AA335375 BC000644 AA654602 BU740772 
AI081982 BM919108 BE043996 AI142305 AA687774 AV715738 BM720065 AA435559 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CD52    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
SP1:                          -               
SP2:                    -     -               
SP3:                                          


ECgene alternative splicing isoforms for CD52

Expression
for CD52 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CD52 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGGCAACAG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

CD52 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell 
Tissue Anatomical Compartment CellCategory (developmental path)
AdiposeBody Subcutaneous White AdiposeAdipose
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See CD52 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CD52

SOURCE GeneReport for Unigene cluster: Hs.276770
    SABiosciences Custom PCR Arrays for CD52
Primer
Products:		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD52
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD52
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD52
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD52
In Situ
Assay Products: 
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CD52

Orthologs
for CD52 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of human and mouse.

Orthologs for CD52 gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia Cd525 CD52 antigen   --   4 (66.50 cM) 134082448 


ENSEMBL Gene Tree for CD52 (if available)
TreeFam Gene Tree for CD52 (if available) 

Paralogs
for CD52 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for CD52 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/96 NCBI SNPs in CD52 are shown (see all 96)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 1 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs124078791,2
C,H--24897016(+) AGGGAG/AAGTGG 1 -- int1 trp34Minor allele frequency- A:0.00NS EA 408
rs124078801,2
C,H--24897026(+) GGCCAG/AAGCTG 1 -- int14Minor allele frequency- A:0.00NS EA 410
rs747825311,2
--24897186(+) GGTCAA/CATGAG 1 -- int11Minor allele frequency- C:0.01NA 120
rs1163876791,2
C--24897389(+) NNNNCA/CCAGCC 1 -- int10--------
rs799600981,2
C,--24897546(+) TGGGCG/ACGGTG 1 -- int12Minor allele frequency- A:0.08WA 120
rs120888191,2
C,--24897705(+) acacaT/Cctgta 1 -- int11Minor allele frequency- C:0.00WA 2
rs120888581,2
C,--24897807(+) caaaaC/Atctgt 1 -- int14Minor allele frequency- A:0.10WA NA EA 360
rs802901831,2
--24898102(+) TTCAGC/TTCCTA 1 -- int11Minor allele frequency- T:0.01EA 120
rs1113388691,2
--24898213(+) TTCTTT/CTGTTA 1 -- int12Minor allele frequency- C:0.03CSA WA 119
rs412853471,2
C,--24898498(+) CACCCC/TGCCTC 1 -- int13Minor allele frequency- T:0.14WA NA 240

HapMap Linkage Disequilibrium report for CD52 (26644411 - 26647014 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CD52: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD52
DNA2.0 Custom Variant and Variant Library Synthesis for CD52

Disorders / Diseases
for CD52 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
CD52 for disorders           About GeneDecksing

OMIM gene information: 114280    OMIM disorders: --

20/33 diseases for CD52 (see all 33):    About MalaCards
relapsing-remitting multiple sclerosis    paroxysmal nocturnal hemoglobinuria    large granular lymphocyte leukemia    waldenstrom macroglobulinemia
prolymphocytic leukemia    non-hodgkin lymphoma    autoimmune hemolytic anemia    hemolytic anemia
demyelinating polyneuropathy    t-cell prolymphocytic leukemia    hairy cell leukemia    hemoglobinuria
mantle cell lymphoma    multiple sclerosis    lymphoid leukemia    lymphocytic leukemia
macroglobulinemia    aplastic anemia    hodgkin's lymphoma    rheumatoid arthritis

3 diseases from the University of Copenhagen DISEASES database for CD52:
Chronic lymphocytic leukemia     Lymphoma     Leukopenia

10/11 Novoseek disease relationships for CD52 gene (see all 11)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cll refractory 73.4 1 15325705 (1)
leukemia lymphocytic chronic 68.2 4 11999566 (1), 17624249 (1), 17960607 (1), 19642457 (1)
lymphoproliferative disorders 57.3 3 11999566 (1), 17624249 (1), 17428002 (1), 16371014 (1)
leukaemia lymphocytic 50.7 2 16371014 (1), 11792397 (1)
lymphoma t-cell 39.7 1 16371014 (1)
lymphoma non-hodgkins 37.2 3 11807632 (1), 9126378 (1), 8027367 (1)
lymphoma 24 3 11999566 (1), 10524207 (1)
autoimmune diseases 21 1 11792397 (1)
multiple sclerosis 15.4 2 8624684 (1), 9345418 (1)
rheumatoid arthritis 15.3 3 7718516 (1), 8707338 (1), 9126378 (1)

Human Genome Epidemiology (HuGE) Navigator: CD52 (1 document)

Export disorders for CD52 gene to outside databases

Publications
for CD52 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CD52 gene, integrated from 9 sources (see all 114):
(articles sorted by number of sources associating them with CD52)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. (PubMed id 1711975)1, 2, 3 Xia M.-Q.... Waldmann H. (1991)
  2. A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone. (PubMed id 8418821)1, 2, 9 Kirchhoff C.... Ivell R. (1993)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol- anchored glycoprotein which is an exceptionally good target for complement lysis. (PubMed id 7688956)1, 2 Xia M.Q.... Waldmann H. (1993)
  5. Different levels of CD52 antigen expression evaluated by quantitative fluorescence cytometry are detected on B-lymphocytes, CD 34+ cells and tumor cells of patients with chronic B-cell lymphoproliferative diseases. (PubMed id 17428002)1, 9 Klabusay M....Mayer J. (2007)
  6. Structure and chromosomal location of mouse and human CD52 genes. (PubMed id 10524207)1, 9 Tone M.... Waldmann H. (1999)
  7. Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. (PubMed id 7718516)1, 9 Rowan W.C....Brett S.J. (1995)
  8. Surface and mRNA expression of the CD52 antigen by human eosinophils but not by neutrophils. (PubMed id 8977262)1, 9 Elsner J....Kapp A. (1996)
  9. The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen. (PubMed id 17624925)1, 9 Flori F....Giovampaola C.D. (2008)
  10. CD52 antigen--a review. (PubMed id 11257744)1, 9 Domagal/a A. and Kurpisz M. (2001)

External Searches for CD52 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing CD52 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 1043 HGNC: 1804 AceView: CDW52 Ensembl:ENSG00000169442 euGenes: HUgn1043
ECgene: CD52 H-InvDB: CD52

Other Databases showing CD52 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing CD52 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for CD52 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CD52 Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property
for CD52 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for CD52 gene:
Search GeneIP for patents involving CD52

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for CD52 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
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 OriGene Antibodies for CD52   OriGene shRNA RFP for CD52  
 OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CD52   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD52  
 OriGene Protein Over-expression Lysate for CD52   Browse OriGene Fluorogenic Cell Assay Kits  
 OriGene siRNA for CD52   OriGene 3'-UTR Clone for CD52  
 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD52   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD52  
 Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
 Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
 OriGene Purified Protein for CD52   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CD52   OriGene Custom Protein Services for CD52  
 OriGene Custom Immunoassay Development  

 		 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CD52
 QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD52
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD52
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD52
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD52
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD52
 GenScript Custom Purified and Recombinant Proteins Services for CD52 GenScript cDNA clones with any tag delivered in your preferred vector for CD52
 GenScript Custom Assay Services for CD52 GenScript Custom Superior Antibodies Services for CD52
 GenScript Custom overexpressing Cell Line Services for CD52 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
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 Regulatory tfbs in CD52 promoter
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 RT2 qPCR Primer Assay in human, mouse / rat CD52
 GNC Network for CD52
 SABiosciences Custom PCR Arrays for CD52
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 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 CD52 antibodies
 CD52 lysates
 Search for Antibodies for CD52 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for CD52
 Custom Antibody / Protein Production Service
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 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 CD52 Proteins, Antibodies, CLIAs, and ELISAs
 Search LifeMap BioReagents cell lines for CD52
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CD52
 SwitchGear 3'UTR luciferase reporter plasmids for CD52
 SwitchGear Promoter luciferase reporter plasmids for CD52
 ThermoFisher Antibodies for CD52
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD52
       
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