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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

CD40 Gene

protein-coding   GIFtS: 69
GCID: GC20P044746

CD40 Molecule, TNF Receptor Superfamily Member 5

(Previous names: tumor necrosis factor receptor superfamily, member 5)
(Previous symbol: TNFRSF5)
Microbiology & Infectious Diseases Congress
  See related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

CD40 Molecule, TNF Receptor Superfamily Member 51 2     B Cell-Associated Molecule2
TNFRSF51 2 3 5     CD40 Antigen (TNF Receptor Superfamily Member 5)2
Tumor Necrosis Factor Receptor Superfamily, Member 51 2     CD40 Type II Isoform2
Bp502 3     Nerve Growth Factor Receptor-Related B-Lymphocyte Activation Molecule2
B-Cell Surface Antigen CD402 3     p502
CD40L Receptor2 3     Tumor Necrosis Factor Receptor Superfamily Member 52
CDW402     CDw403
B Cell Surface Antigen CD402     CD40 Antigen3

External Ids:    HGNC: 119191   Entrez Gene: 9582   Ensembl: ENSG000001010177   OMIM: 1095355   UniProtKB: P259423   

Export aliases for CD40 gene to outside databases

Previous GC identifers: GC20P044181 GC20P041488

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD40 Gene:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be
essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent
immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription
factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be
important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a
mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for
amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease
pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been
reported. (provided by RefSeq, Jul 2008)

GeneCards Summary for CD40 Gene: 
CD40 (CD40 molecule, TNF receptor superfamily member 5) is a protein-coding gene. Diseases associated with CD40 include cd40 deficiency, and chromosome 20q deletion, and among its related super-pathways are TNF Signaling and Toll-like receptor signaling pathway. GO annotations related to this gene include receptor activity and signal transducer activity. An important paralog of this gene is TNFRSF21.

UniProtKB/Swiss-Prot: TNR5_HUMAN, P25942
Function: Receptor for TNFSF5/CD40LG

Gene Wiki entry for CD40 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011362.10  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD40 gene promoter:
         c-Fos   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CD40 promoter sequence
   Search SABiosciences Chromatin IP Primers for CD40

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD40

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q12-q13.2   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q12-q13.2

CD40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD40 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P044746:  view genomic region     (about GC identifiers)

44,746,906 bp from pter      End:
44,758,502 bp from pter
11,597 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TNR5_HUMAN, P25942 (See protein sequence)
Recommended Name: Tumor necrosis factor receptor superfamily member 5 precursor  
Size: 277 amino acids; 30619 Da
Subunit: Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form
homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6
Subcellular location: Isoform I: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform II: Secreted
6 PDB 3D structures from and Proteopedia for CD40:
1CDF (3D)        1CZZ (3D)        1D00 (3D)        1FLL (3D)        1LB6 (3D)        3QD6 (3D)    
Secondary accessions: E1P5S9 Q53GN5 Q5JY15 Q5U007 Q7M4Q8 Q86YK5 Q9BYU0
Alternative splicing: 2 isoforms:  P25942-1   P25942-2   

Explore the universe of human proteins at neXtProt for CD40: NX_P25942

Explore proteomics data for CD40 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P25942

  • CD40 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CD40 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001241.1  NP_690593.1  

    ENSEMBL proteins: 
     ENSP00000361359   ENSP00000361350   ENSP00000434825  
    Reactome Protein details: P25942
    Human Recombinant Protein Products for CD40: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CD40 (CD40/TNFRSF5)
    Enzo Life Sciences proteins for CD40
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CD40
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for CD40
    GenScript Purified and Recombinant Proteins for CD40
    Novus Biologicals CD40 Proteins
    Novus Biologicals CD40 Lysates
    Sino Biological Recombinant Protein for CD40
    Sino Biological Cell Lysate for CD40 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS10748139
    GO:0009897external side of plasma membrane IEA--
    GO:0009986cell surface ----

    CD40 for ontologies           About GeneDecksing

    CD40 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CD40 (CD40/TNFRSF5)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CD40
    GenScript Custom Superior Antibodies Services for CD40
    Novus Biologicals CD40 Antibodies
    Abcam antibodies for CD40
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibodies for CD40
    LSBio Antibodies in human, mouse, rat for CD40 

    Assay Products for CD40: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CD40
    R&D Systems ELISAs for CD40 (CD40/TNFRSF5)         (see all)
    GenScript Custom Assay Services for CD40
    Enzo Life Sciences assays for CD40
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    TNFRSF: Tumor necrosis factor receptor superfamily

    IUPHAR Guide to PHARMACOLOGY protein family classification: CD40 
    Tumour necrosis factor (TNF) receptor family

    2 InterPro protein domains:
     IPR020435 TNFR_5
     IPR001368 TNFR/NGFR_Cys_rich_reg

    Graphical View of Domain Structure for InterPro Entry P25942

    ProtoNet protein and cluster: P25942

    2 Blocks protein domains:
    IPB001368 TNFR/CD27/30/40/95 cysteine-rich region
    IPB008063 FAS/CD95 receptor family signature

    UniProtKB/Swiss-Prot: TNR5_HUMAN, P25942
    Similarity: Contains 4 TNFR-Cys repeats

    CD40 for domains           About GeneDecksing

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TNR5_HUMAN, P25942
    Function: Receptor for TNFSF5/CD40LG

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity TAS9671306
    GO:0004872receptor activity TAS10092834
    GO:0005515protein binding IPI12140561
    GO:0019899enzyme binding IPI12223522
    GO:0031625ubiquitin protein ligase binding IPI11279055
    CD40 for ontologies           About GeneDecksing

         8 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Cd40):
     cellular  hematopoietic system  homeostasis/metabolism  immune system  nervous system 
     normal  renal/urinary system  skeleton 

    CD40 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for CD40: Cd40tm1Geha Cd40tm1Kik Cd40tm1Arah

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CD40 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD40

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD40 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD40 

    miRTarBase miRNAs that target CD40:
    hsa-mir-486-5p (MIRT004620), hsa-mir-224 (MIRT003393)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD40
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate CD40:
    hsa-miR-30c-2* hsa-miR-30c-1* hsa-miR-575 hsa-miR-145 hsa-miR-3165 hsa-miR-3155 hsa-miR-3155b hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidCD40 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD40
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD40

    Gene Editing
    DNA2.0 Custom Protein Engineering Service for CD40
    Sirion Biotech Customized adenovirus for overexpression of CD40

    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CD40 (see all 16)
    OriGene ORF clones in mouse, rat for CD40
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CD40 (NM_152854)
    Sino Biological Human cDNA Clone for CD40
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD40
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD40
    Sirion Biotech Customized lentivirus for stable overexpression of CD40 
                         Customized lentivirus expression plasmids for stable overexpression of CD40 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for CD40
    Search LifeMap BioReagents cell lines for CD40
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD40

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CD40 About   (see all 21)                                                                                              See pathways by source

    SuperPathContained pathways About
    1TNF Signaling
    TNF Signaling0.50
    TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions0.49
    Death Receptor Signaling0.50
    NF-kB (NFkB) Pathway0.46
    2Toll-like receptor signaling pathway
    Toll-like receptor signaling pathway0.93
    Toll-like receptor signaling pathway0.93
    3Allograft rejection
    Allograft rejection0.69
    Intestinal immune network for IgA production0.42
    Autoimmune thyroid disease0.62
    Viral myocarditis0.35
    4Immune System
    Immune System0.56
    Adaptive Immune System0.56
    5Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
    Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway0.46

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for CD40
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway

    2 R&D Systems Pathways for CD40
        TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions
    A-beta Uptake & Degradation

    1 GeneGo (Thomson Reuters) Pathway for CD40
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway

    5 BioSystems Pathways for CD40
        NLR proteins
    Toll-like receptor signaling pathway
    IL-6 Signaling Pathway
    CD40/CD40L signaling
    Inflammatory Response Pathway

    3 Sino Biological Pathways for CD40 
        TNF Signaling
    Death Receptor Signaling
    NF-kB (NFkB) Pathway

    3        Reactome Pathways for CD40
        Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
    Adaptive Immune System
    Immune System

    5/16         Kegg Pathways  (Kegg details for CD40) (see all 16):
        Cytokine-cytokine receptor interaction
    NF-kappa B signaling pathway
    Cell adhesion molecules (CAMs)
    Toll-like receptor signaling pathway
    Intestinal immune network for IgA production

    CD40 for pathways           About GeneDecksing


        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CD40

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/77 Interacting proteins for CD40 (P259421, 3 ENSP000003613594) via UniProtKB, MINT, STRING, and/or I2D (see all 77)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAF6Q9Y4K31, 3EBI-525714,EBI-359276 I2D: score=7 
    ENSG00000229802Q925043, ENSP000003917354I2D: score=2 STRING: ENSP00000391735
    SLC39A7Q925043, ENSP000003638074I2D: score=2 STRING: ENSP00000363807
    ENSG00000206288Q925043I2D: score=2 
    ENSG00000224399Q925043I2D: score=2 
    About this table

    Gene Ontology (GO): 5/24 biological process terms (GO ID links to tree view) (see all 24):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001934positive regulation of protein phosphorylation IMP--
    GO:0002768immune response-regulating cell surface receptor signaling pathway IEA--
    GO:0006461protein complex assembly TAS10748139
    GO:0006874cellular calcium ion homeostasis IMP--
    GO:0006954inflammatory response TAS2475341

    CD40 for ontologies           About GeneDecksing

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CD40 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CD40 (TNR5)

    1 HMDB Compound for CD40    About this table
    CompoundSynonyms CAS #PubMed Ids
    Simvastatin(+)-Simvastatin (see all 28)79902-63-9--

    1 IUPHAR Ligand for CD40 (CD40)    About this table 
    LigandTypeActionAffinityPubmed IDs
    CD40 ligand

    10/116 Novoseek inferred chemical compound relationships for CD40 gene (see all 116)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lfa703 69.8 4 15618295 (3), 17482516 (1)
    rantes 59.7 36 16864989 (8), 11274230 (5), 12122011 (3), 11754818 (1) (see all 18)
    blys 55.5 12 19421221 (3), 17567982 (2), 11015437 (1), 12154359 (1) (see all 6)
    ionomycin 48.9 9 1708162 (1), 16223731 (1), 9727564 (1), 7699321 (1) (see all 9)
    pdtc 47.1 3 20037166 (1), 12901869 (1), 16141529 (1)
    triazolopyrimidine 43.2 7 10600333 (5)
    sb 203580 43 5 16356505 (1), 11708812 (1), 12209089 (1), 17911635 (1)
    n-tosyl-l-phenylalanine chloromethyl ketone 37 1 10995749 (1)
    pd 98,059 36 5 16272352 (1), 16904975 (1), 19288477 (1), 10586056 (1)
    ly294002 35.9 2 15888255 (1), 18174238 (1)

    Search CenterWatch for drugs/clinical trials and news about CD40 / TNR5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CD40 gene (2 alternative transcripts): 
    NM_001250.4  NM_152854.2  

    Unigene Cluster for CD40:

    CD40 molecule, TNF receptor superfamily member 5
    Hs.472860  [show with all ESTs]
    Unigene Representative Sequence: AB209660
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372285(uc002xrf.1 uc002xrg.1 uc002xrh.1 uc002xrj.1 uc002xrk.1)
    ENST00000372276 ENST00000466205 ENST00000489304 ENST00000477696 ENST00000461171

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD40
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate CD40:
    hsa-miR-30c-2* hsa-miR-30c-1* hsa-miR-575 hsa-miR-145 hsa-miR-3165 hsa-miR-3155 hsa-miR-3155b hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidCD40 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD40
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD40
    OriGene clones in human, mouse for CD40 (see all 16)
    OriGene ORF clones in mouse, rat for CD40
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CD40 (NM_152854)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD40
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD40
    Sirion Biotech Customized lentivirus for stable overexpression of CD40 
                         Customized lentivirus expression plasmids for stable overexpression of CD40 
    OriGene qPCR primer pairs and template standards for CD40
    OriGene qSTAR qPCR primer pairs in human, mouse for CD40
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CD40
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD40
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD40

    Additional mRNA sequence: 

    AB209660.1 AJ300189.1 AK222896.1 AY225405.1 BC012419.1 BC064518.1 BT019901.1 

    9 DOTS entries:

    DT.451574  DT.100791759  DT.86853137  DT.100791764  DT.92423397  DT.102104  DT.95170181  DT.40204598 

    24/119 AceView cDNA sequences (see all 119):

    BI759406 AI267899 CA307201 CA944736 CR619622 BM708033 BM456032 AI791563 
    BC012419 AA934395 NM_001250 NM_152854 BM707407 CK826276 AI620202 CA417566 
    AA749024 BF797410 AA767182 CA305932 AI674469 H50599 BQ548631 AA876065 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CD40    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:              -                                   -           -         
    SP2:              -                       -     -                 -         
    SP3:                                      -           -           -         
    SP4:                                                  -                     

    ECgene alternative splicing isoforms for CD40

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CD40 expression in normal human tissues (normalized intensities)      CD40 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CD40 Expression
    About this image

    CD40 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/11 selected tissues (see all 11) fully expand
     Blood (Hematopoietic System)    fully expand to see all 11 entries
             Monocytes Peripheral Blood
             Immunosuppressive dendritic cells
             b cells   
     Dermis (Integumentary System)    fully expand to see all 3 entries
             Dermal Fibroblasts Dorsal Dermis
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Periosteum
             Bone marrow-derived mesenchymal stem cells
     Lymph (Hematopoietic System)    fully expand to see all 2 entries
             LYMPH NODE   
     Spleen (Hematopoietic System)
             spleen ; cells in white pulp   

    See CD40 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CD40

    SOURCE GeneReport for Unigene cluster: Hs.472860

    UniProtKB/Swiss-Prot: TNR5_HUMAN, P25942
    Tissue specificity: B-cells and in primary carcinomas

        SABiosciences Expression via Pathway-Focused PCR Arrays including CD40 (see all 21): 
              Cell Surface Markers in human mouse rat
              Antiviral Response in human mouse rat
              Multiple Sclerosis in human mouse rat
              Lymphoma in human mouse rat
              T-cell & B-cell Activation in human mouse rat

    OriGene qPCR primer pairs and template standards for CD40
    OriGene qSTAR qPCR primer pairs in human, mouse for CD40
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CD40
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD40
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD40
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD40

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CD40 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Cd401 , 5 CD40 antigen1, 5 71.29(n)1
      2 (85.38 cM)5
    219391  NM_011611.21  NP_035741.21 
    (Gallus gallus)
    Aves CD401 CD40 molecule, TNF receptor superfamily member 5 52.58(n)
      395385  NM_204665.1  NP_989996.1 
    (Anolis carolinensis)
    Reptilia CD406
    Uncharacterized protein
    1 ↔ 1
    (Danio rerio)
    Actinopterygii cd406
    CD40 antigen
    1 ↔ 1

    ENSEMBL Gene Tree for CD40 (if available)
    TreeFam Gene Tree for CD40 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68)
    About This Section
    Paralogs for CD40 gene
    3 SIMAP similar genes for CD40 using alignment to 3 protein entries:     TNR5_HUMAN (see all proteins):

    CD40 for paralogs           About GeneDecksing

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/351 SNPs in CD40 are shown (see all 351)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 20 posSequence#AA
    Bladder carcinoma cell line Hu5494--see VAR_0393022 S G mis40--------
    Bladder carcinoma cell line Hu5494--see VAR_0393012 C Q mis40--------
    Bladder carcinoma cell line Hu5494--see VAR_0393032 S T mis40--------
    CImmunodeficiency with hyper-IgM 3 (HIGM3)4 pathogenic144721508(+) AATACC/TGCGAC 4 R C mis1 ese30--------
    F--44715482(+) GTGAGG/ATCTGG 2 -- us2k11Minor allele frequency- A:0.01NA 120
    --44715658(+) GAGTGC/TTAACA 2 -- us2k10--------
    --44715916(+) GAGCCG/TAGATC 2 -- us2k10--------
    F--44715976(+) AACCCA/CAAAAC 2 -- us2k11Minor allele frequency- C:0.08WA 118
    --44716005(+) CCAAAA/GAACAA 2 -- us2k10--------
    C,F--44716413(+) CTCAAG/CCAATC 2 -- us2k11Minor allele frequency- C:0.04WA 118

    HapMap Linkage Disequilibrium report for CD40 (44746906 - 44758502 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CD40:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv833993CNV Gain17160897
    dgv1329e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): CD40

    Locus Specific Mutation Databases (LSDB): CD40
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CD40
    DNA2.0 Custom Variant and Variant Library Synthesis for CD40

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 109535   
    OMIM disorders: 606843  
    UniProtKB/Swiss-Prot: TNR5_HUMAN, P25942
  • Immunodeficiency with hyper-IgM 3 (HIGM3) [MIM:606843]: A rare immunodeficiency syndrome characterized by
    normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to
    bacterial infections. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 20/166 diseases for CD40 (see all 166):    About MalaCards
    cd40 deficiency    chromosome 20q deletion    critical limb ischemia    plasma cell leukemia
    x-linked hyper igm syndrome    frozen shoulder    macroglobulinemia    waldenstrom macroglobulinemia
    monocytic leukemia    autoimmune thrombocytopenic purpura    hiv-1, resistance to    cervical squamous cell carcinoma
    graves' disease    langerhans-cell histiocytosis    aphthous stomatitis    acute monocytic leukemia
    histiocytosis    agammaglobulinemia    primary immunodeficiency disease    lupus nephritis

    12 diseases from the University of Copenhagen DISEASES database for CD40:
    Lymphoma     Hypersensitivity reaction type II disease     Primary immunodeficiency disease     Leukemia
    Atherosclerosis     Connective tissue disease     Multiple sclerosis     Multiple myeloma
    Blood protein disease     Rheumatoid arthritis     Tetanus     Hyperthyroidism

    CD40 for disorders           About GeneDecksing

    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/93 Novoseek inferred disease relationships for CD40 gene (see all 93)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hyper-igm syndrome 80.7 23 9058789 (3), 14752331 (2), 11358428 (2), 10559240 (1) (see all 14)
    higm3 77.3 3 15661021 (1), 14610488 (1), 12893749 (1)
    necrosis 74.5 256 9511754 (3), 14517219 (2), 10096561 (2), 10318845 (2) (see all 99)
    tumors 61.1 374 8623911 (6), 11304696 (6), 10980464 (5), 10473114 (4) (see all 99)
    m syndrome 59 2 15661021 (1), 8914765 (1)
    inflammation 56.9 68 11488834 (2), 19183933 (2), 12209092 (2), 19834879 (2) (see all 52)
    autoimmune diseases 49.4 15 9617563 (1), 17114447 (1), 12223069 (1), 19421221 (1) (see all 12)
    atherosclerosis 48 21 17967972 (2), 15921025 (1), 16904975 (1), 19896127 (1) (see all 19)
    lymphocytic leukemia chronic b-cell 44.7 7 1281692 (2), 11313271 (1), 11426465 (1), 9531577 (1) (see all 6)
    lymphoma 43.3 52 7530508 (3), 7541711 (3), 11825564 (3), 9137085 (2) (see all 30)

    Genetic Association Database (GAD): CD40
    Human Genome Epidemiology (HuGE) Navigator: CD40 (89 documents)

    Export disorders for CD40 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CD40 gene, integrated from 9 sources (see all 1592) (see top 10):
    (articles sorted by number of sources associating them with CD40)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization. (PubMed id 9718306)1, 2, 9 Pullen S.S....Kehry M.R. (1998)
    2. Association analysis of CD40 polymorphisms with asthma and the level of serum total IgE. (PubMed id 17255560)1, 4, 9 Park J.H....Shin H.D. (2007)
    3. Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions. (PubMed id 19735272)1, 4, 9 Kim S.H....Park H.W. (2009)
    4. Individual and epistatic effects of genetic polymorphisms of B-cell co-stimulatory molecules on susceptibility to pemphigus foliaceus. (PubMed id 19421221)1, 4, 9 Malheiros D. and Petzl-Erler M.L. (2009)
    5. Downstream regulator TANK binds to the CD40 recognition site on TRAF3. (PubMed id 12005438)1, 2, 9 Li C.... Ely K.R. (2002)
    6. Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells. (PubMed id 11676606)1, 2, 9 Khandekar S.S....Fishman-Lobell J. (2001)
    7. Molecular basis for CD40 signaling mediated by TRAF3. (PubMed id 10984535)1, 2, 9 Ni C.Z.... Ely K.R. (2000)
    8. The role of polar interactions in the molecular recognition of CD40L with its receptor CD40. (PubMed id 9605317)1, 2, 9 Singh J.... Thomas D. (1998)
    9. Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease. (PubMed id 16279844)1, 4, 9 Kurylowicz A....Bednarczuk T. (2005)
    10. Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5). (PubMed id 9511754)1, 2, 9 Mizushima S.... Inoue J. (1998)
    11. Common variants at CD40 and other loci confer risk of rheumatoid arthritis. (PubMed id 18794853)1, 4, 9 Raychaudhuri S....Plenge R.M. (2008)
    12. [Association between inflammatory cytokine CD40 gene polymorphism and risk of acute coronary syndrome] (PubMed id 19099972)1, 4, 9 Tian C.X....Huang C.X. (2008)
    13. Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS). (PubMed id 16504636)1, 4, 9 Burdon K.P....Bowden D.W. (2006)
    14. A C/T polymorphism in the 5' untranslated region of the CD40 gene is associated with later onset of Graves' disease in Japanese. (PubMed id 16127217)1, 4, 9 Mukai T....Yamada K. (2005)
    15. Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM. (PubMed id 11675497)1, 2, 9 Ferrari S....Plebani A. (2001)
    16. Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway. (PubMed id 9432981)1, 2, 9 Kashiwada M.... Takemori T. (1998)
    17. A genome-wide association study identifies three new r isk loci for Kawasaki disease. (PubMed id 22446962)1, 4 Onouchi Y.... . (2012)
    18. Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1. (PubMed id 20797713)1, 4 Sundqvist J....D'Hooghe T.M. (2011)
    19. Investigation of potential non-HLA rheumatoid arthrit is susceptibility loci in a European cohort increases the evidence for nine mar kers. (PubMed id 20498205)1, 4 Plant D....Worthington J. (2010)
    20. Cumulative association of 22 genetic variants with se ropositive rheumatoid arthritis risk. (PubMed id 20233754)1, 4 Karlson E.W....Plenge R.M. (2010)
    21. Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans. (PubMed id 20650312)1, 4 Lewis J.P....Bowden D.W. (2010)
    22. CD40: novel association with Crohn's disease and repl ication in multiple sclerosis susceptibility. (PubMed id 20634952)1, 4 Blanco-Kelly F....Urcelay E. (2010)
    23. Genetic variants in the prediction of rheumatoid arth ritis. (PubMed id 20439292)1, 4 van der Helm-van Mil A.H....Huizinga T.W. (2010)
    24. Genome-wide association study meta-analysis identifie s seven new rheumatoid arthritis risk loci. (PubMed id 20453842)1, 4 Stahl E.A....Plenge R.M. (2010)
    25. A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis. (PubMed id 20049410)1, 4 Wieczorek S....Epplen J.T. (2010)
    26. Association of CD40 with rheumatoid arthritis confirm ed in a large UK case-control study. (PubMed id 19435719)1, 4 Orozco G....Ke X. (2010)
    27. A common polymorphism in CD40 Kozak sequence (-1C/T) is associated with acute coronary syndrome. (PubMed id 20137882)1, 4 Tian C....Qiu F. (2010)
    28. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    29. Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077)1, 4 Ban H.J....Park K.J. (2010)
    30. Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-t umour necrosis factor treatment. (PubMed id 20444755)1, 4 Tan R.J....Barton A. (2010)
    31. A functional TNFRSF5 polymorphism and risk of non-Hod gkin lymphoma, a pooled analysis. (PubMed id 20473910)1, 4 Nieters A....Skibola C.F. (2010)
    32. Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis. (PubMed id 19674979)1, 4 Hinks A....Packham J. (2010)
    33. The relationship between CD40 gene polymorphism and u nstable coronary atherosclerotic plaques. (PubMed id 20552594)1, 4 Wang C....Chen G. (2010)
    34. Common single nucleotide polymorphisms in immunoregul atory genes and multiple myeloma risk among women in Connecticut. (PubMed id 20568250)1, 4 Lee K.M....Lan Q. (2010)
    35. The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. (PubMed id 20190274)1, 4 Gandhi K.S....Booth D.R. (2010)
    36. CD40-1C>T polymorphism (rs1883832) is associated w ith brain vessel reocclusion after fibrinolysis in ischemic stroke. (PubMed id 20504251)1, 4 del RA-o-EspA-nola A....Montaner J. (2010)
    37. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (2010)
    38. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    39. Influence of CD40 rs1883832 polymorphism in susceptib ility to and clinical manifestations of biopsy-proven giant cell arteritis. (PubMed id 20682661)1, 4 RodrA-guez-RodrA-guez L....GonzA!lez-Gay M.A. (2010)
    40. Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. (PubMed id 20716621)1, 4 Chang J.S....Buffler P.A. (2010)
    41. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (2009)
    42. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (2009)
    43. Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations. (PubMed id 19180477)1, 4 Lee H.S....Bae S.C. (2009)
    44. Association analysis of CD40 gene polymorphism with acute coronary syndrome. (PubMed id 19246174)1, 4 Yan J....Chen G. (2009)
    45. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
    46. Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. (PubMed id 19525955)1, 4 (2009)
    47. Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (2009)
    48. Common genetic variants in candidate genes and risk o f familial lymphoid malignancies. (PubMed id 19573080)1, 4 Liang X.S....Goldin L.R. (2009)
    49. STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma. (PubMed id 19159017)1, 4 Hsieh Y.Y....Tsai F.J. (2009)
    50. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    51. Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus. (PubMed id 19110536)1, 4 Fung E.Y....Todd J.A. (2009)
    52. Association of CD40 -1C/T polymorphism in the 5'-untr anslated region and chronic obstructive pulmonary disease. (PubMed id 19622350)1, 4 Liu Y....Zhang L. (2009)
    53. Association of a single-nucleotide polymorphism in CD 40 with the rate of joint destruction in rheumatoid arthritis. (PubMed id 19644859)1, 4 van der Linden M.P....van der Helm-Van Mil A.H. (2009)
    54. Association of CD40 and thyroglobulin genes with later-onset Graves' disease in Taiwanese patients. (PubMed id 18755875)1, 4 Hsiao J.Y....Ke D.S. (2008)
    55. A functional TNFRSF5 gene variant is associated with risk of lymphoma. (PubMed id 18287517)1, 4 Skibola C.F....Holly E.A. (2008)
    56. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
    57. A C/T polymorphism in CD40 gene is not associated with susceptibility and phenotype of Graves' disease in Taiwanese. (PubMed id 18446002)1, 4 Hsiao J.Y....Hsieh M.C. (2008)
    58. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. (PubMed id 18636124)1, 4 Skibola C.F....Smith M.T. (2008)
    59. A CD40 Kozak sequence polymorphism and susceptibility to antibody-mediated autoimmune conditions: the role of CD40 tissue-specific expression. (PubMed id 17344890)1, 4 Jacobson E.M....Tomer Y. (2007)
    60. Susceptible alleles of the CD40 and CTLA-4 genes are not associated with the relapse after antithyroid withdrawal in Graves' disease. (PubMed id 17949264)1, 4 Kim K.W....Cho B.Y. (2007)
    61. Association and linkage studies of the 20q11.2 region (GRD-2 locus) with Graves' disease in the Tunisian population. (PubMed id 17786592)1, 4 Makni K....Ayadi H. (2007)
    62. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (2007)
    63. [Correlation of CD40 gene polymorphisms with acute coronary syndrome, hypertension and diabetes] (PubMed id 17553307)1, 4 Li Y....Xia Z.E. (2007)
    64. Association of a C/T single-nucleotide polymorphism in the 5' untranslated region of the CD40 gene with Graves' disease in Japanese. (PubMed id 16756465)1, 4 Ban Y....Ban Y. (2006)
    65. Analysis of the C/T(-1) single nucleotide polymorphism in the CD40 gene in multiple sclerosis. (PubMed id 17026470)1, 4 Buck D....Wiendl H. (2006)
    66. A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians. (PubMed id 15272925)1, 4 Heward J.M....Gough S.C. (2004)
    67. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    68. Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population. (PubMed id 15301860)1, 4 Cho S.M....Lee J.K. (2004)
    69. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    70. Variants in TNFRSF5 locus and association analysis with Hepatitis B virus (HBV) infection. (PubMed id 14695541)1, 4 Zhou G....He F. (2004)
    71. CD40 ligand gene and Kawasaki disease. (PubMed id 15367912)1, 4 Onouchi Y....Hata A. (2004)
    72. A C/T polymorphism in the 5'-untranslated region of the CD40 gene is associated with Graves' disease in Koreans. (PubMed id 14611700)1, 4 Kim T.Y....Park D.J. (2003)
    73. Regulation of CD40 function by its isoforms generated through alternative splicing. (PubMed id 11172023)1, 2 Tone M.... Waldmann H. (2001)
    74. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    75. Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40. (PubMed id 9037712)1, 2 Bajorath J. and Aruffo A. (1997)
    76. A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40. (PubMed id 7530216)1, 2 Sato T.... Reed J.C. (1995)
    77. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. (PubMed id 7533327)1, 2 Cheng G.... Baltimore D. (1995)
    78. Chromosomal localization of the gene for human B-cell antigen CD40. (PubMed id 7687385)1, 3 Ramesh N....Geha R. (1993)
    79. A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. (PubMed id 2475341)1, 2 Stamenkovic I.... Seed B. (1989)
    80. A p50 surface antigen restricted to human urinary bladder carcinomas and B lymphocytes. (PubMed id 2998589)1, 3 Paulie S....Perlmann P. (1985)
    81. Effect of 15d-PGJ2 on the expression of CD40 and RANTES induced by IFN-gamma and TNF-alpha on renal tubular epithelial cells (HK-2). (PubMed id 16864989)1, 9 Zhang Y.J....Yu X.Q. (2006)
    82. CD40-mediated death and cytokine secretion in colorectal cancer: a potential target for inflammatory tumour cell killing. (PubMed id 17534894)1, 9 Georgopoulos N.T....Trejdosiewicz L.K. (2007)
    83. Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo. (PubMed id 18603231)1, 9 Wu Y....Zhang Y. (2008)
    84. CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses. (PubMed id 12576427)1, 9 Hakkarainen T....Curiel D.T. (2003)
    85. [Expression of CD40 and CD40 ligand in peripheral blood mononuclear cells in children with bronchiolitis.] (PubMed id 19470255)1, 9 Zhu P. and Zou L.P. (2009)
    86. CD40 expression in HCV-associated chronic liver diseases. (PubMed id 16964404)1, 9 Shiraki K....Nakano T. (2006)
    87. CD40: a mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells. (PubMed id 16033859)1, 9 Laxmanan S....Pal S. (2005)
    88. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. (PubMed id 12676820)1, 9 Inwald D.P....Klein N.J. (2003)
    89. Molecular characterization of CD40 signaling intermediates. (PubMed id 11562359)1, 9 Werneburg B.G....Crute J.J. (2001)
    90. CD40 expression and its association with low-grade in flammation in a Greek population of type 1 diabetic juveniles: evidence for dif ferences in CD40 mRNA isoforms expressed by peripheral blood mononuclear cells. (PubMed id 19834879)1, 9 Chatzigeorgiou A.E....Kamper E.F. (2010)
    91. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response. (PubMed id 17967972)1, 9 Korff T....Hecker M. (2007)
    92. Molecular regulation of CD40 gene expression in macrophages and microglia. (PubMed id 14651941)1, 9 Benveniste E.N....Wesemann D.R. (2004)
    93. CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation. (PubMed id 12209092)1, 9 Bureau F....Lekeux P. (2002)
    94. Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesis. (PubMed id 7543281)1, 9 Bajorath J....Aruffo A. (1995)
    95. CD40 is a regulator for vascular endothelial growth f actor in the tumor microenvironment of glioma. (PubMed id 20303602)1, 9 Xie F....Zhang X. (2010)
    96. Up-regulation of CD40 with juxtacrine activity in human nonsmall lung cancer cells correlates with poor prognosis. (PubMed id 18548529)1, 9 Ishikawa K....Kondo S. (2008)
    97. Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway. (PubMed id 15708600)1, 9 Harhaj E.W....Wigdahl B. (2005)
    98. Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1). (PubMed id 15838273)1, 9 Sakurai K....Sawamura T. (2004)
    99. Stimulation of CD40 inhibits Fas- or chemotherapy-mediated apoptosis and increases cell motility in human gastric carcinoma cells. (PubMed id 14612943)1, 9 Yamaguchi H....Mori M. (2003)
    100. Critical role of tumor necrosis factor-alpha and NF-kappa B in interferon-gamma -induced CD40 expression in microglia/macrophages. (PubMed id 11830590)1, 9 Nguyen V.T. and Benveniste E.N. (2002)
    101. Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. (PubMed id 9133417)1, 9 Hanissian S.H. and Geha R.S. (1997)
    102. CD154-CD40 interactions are essential for thymus-depe ndent antibody production in zebrafish: insights into the origin of costimulato ry pathway in helper T cell-regulated adaptive immunity in early vertebrates. (PubMed id 19494299)1, 9 Gong Y.F....Shao J.Z. (2009)
    103. A functional CD40 receptor is expressed in pancreatic beta cells. (PubMed id 15690148)1, 9 Klein D....Pastori R.L. (2005)
    104. CD40-CD154 expression in calcified and non-calcified coronary lesions of patients with chronic renal failure. (PubMed id 16494885)1, 9 Campean V....Amann K. (2007)
    105. Persistence of high CD40 and CD40L expression after restorative proctocolectomy for ulcerative colitis. (PubMed id 16149136)1, 9 Polese L....D'Amico D.F. (2005)
    106. Upregulation of CD40--CD40 ligand system in patients with diabetes mellitus. (PubMed id 14687897)1, 9 Jinchuan Y....Xiantao K. (2004)
    107. Cross-species costimulation: relative contributions of CD80, CD86, and CD40. (PubMed id 12829914)1, 9 Rogers N.J....Lechler R.I. (2003)
    108. Immunohistochemical expression of CD23 and CD40 may identify prognostically favorable subgroups of diffuse large B-cell lymphoma: a Nordic Lymphoma Group Study. (PubMed id 12576441)1, 9 Linderoth J....Torlakovic E. (2003)
    109. CD40 activation induces p53-dependent vascular endothelial growth factor secretion in human multiple myeloma cells. (PubMed id 11830495)1, 9 Tai Y.T....Anderson K.C. (2002)
    110. Competition between TRAF2 and TRAF6 regulates NF-kapp aB activation in human B lymphocytes. (PubMed id 20449947)1, 9 Zhang W....Lipsky P.E. (2010)
    111. The CD40-CD40L pathway contributes to the proinflamma tory function of intestinal epithelial cells in inflammatory bowel disease. (PubMed id 20133813)1, 9 Borcherding F....BA1ning J. (2010)
    112. High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95. (PubMed id 18552209)1, 9 Troeger A....Dilloo D. (2008)
    113. CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF- kappaB-mediated de novo synthesis of IRF-1. (PubMed id 18694960)1, 9 Moschonas A....Eliopoulos A.G. (2008)
    114. Coculture of human liver macrophages and cholangiocytes leads to CD40-dependent apoptosis and cytokine secretion. (PubMed id 17999420)1, 9 Alabraba E.B....Afford S.C. (2008)
    115. Role of CD40-dependent down-regulation of CD154 in impaired induction of CD154 in CD4(+) T cells from HIV-1-infected patients. (PubMed id 17237414)1, 9 Subauste C.S....Wessendarp M. (2007)
    116. [Effect of prolactin on CD40/CD154 expression on peripheral blood mononuclear cells in patients with systemic lupus erythematosus] (PubMed id 17884785)1, 9 Wang N....Zeng K. (2007)
    117. TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells. (PubMed id 16260598)1, 9 Davies C.C....Eliopoulos A.G. (2005)
    118. CD40-mediated activation of NF-kappa B in airway epithelial cells. (PubMed id 12122011)1, 9 Propst S.M....Schwiebert L.M. (2002)
    119. Bruton's tyrosine kinase is activated upon CD40 stimulation in human B lymphocytes. (PubMed id 12437073)1, 9 Brunner C....Schuster V. (2002)
    120. CD40 ligand in CLL pathogenesis and therapy. (PubMed id 11042507)1, 9 Schattner E.J. (2000)
    121. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. (PubMed id 9468137)1, 9 Henn V....Kroczek R.A. (1998)
    122. Identification, characterisation and regulation by CD 40 activation of novel CD95 splice variants in CD95-apoptosis-resistant, human, B-cell non-Hodgkin's lymphoma. (PubMed id 19751723)1, 9 Lajmanovich A....Callanan M.B. (2009)
    123. Roles of the TRAF2/3 binding site in differential B c ell signaling by CD40 and its viral oncogenic mimic, LMP1. (PubMed id 19667091)1, 9 Graham J.P....Bishop G.A. (2009)
    124. Mechanisms of LPS-induced CD40 expression in human peripheral blood monocytic cells. (PubMed id 19118532)1, 9 Wu W....Peden D.B. (2009)
    125. Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells. (PubMed id 17237417)1, 9 Pido-Lopez J....Lehner T. (2007)
    126. A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. (PubMed id 16429118)1, 9 Georgopoulos N.T....Trejdosiewicz L.K. (2006)
    127. TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40. (PubMed id 15670770)1, 9 Chan H. and Reed J.C. (2005)
    128. Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation. (PubMed id 14557256)1, 9 Fotin-Mleczek M....Wajant H. (2004)
    129. Increased CD40 expression on articular chondrocytes from patients with rheumatoid arthritis: contribution to production of cytokines and matrix metalloproteinases. (PubMed id 15290728)1, 9 Gotoh H....Kamatani N. (2004)
    130. CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines leading to T-cell transmigration. (PubMed id 14699489)1, 9 Vogel J.D....Fiocchi C. (2004)
    131. Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling. (PubMed id 12810728)1, 9 Contin C....Dechanet-Merville J. (2003)
    132. CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling. (PubMed id 12433678)1, 9 Tai Y.T....Anderson K.C. (2003)
    133. A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. (PubMed id 12885753)1, 9 Longo C.R....Ferran C. (2003)
    134. Disruption of CD40/CD40 ligand interaction with cleavage of CD40 on human gingival fibroblasts by human leukocyte elastase resulting in down-regulation of chemokine production. (PubMed id 12223522)1, 9 Nemoto E....Shimauchi H. (2002)
    135. Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40. (PubMed id 9990007)1, 9 Tsukamoto N....Inoue J. (1999)
    136. HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71). (PubMed id 7541827)1, 9 Chirmule N....Pahwa S. (1995)
    137. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. (PubMed id 7544915)1, 9 Rothe M....Goeddel D.V. (1995)
    138. Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells. (PubMed id 7522634)1, 9 Pellat-Deceunynck C....Amiot M. (1994)
    139. The CD40 antigen and its ligand. (PubMed id 7516669)1, 9 Banchereau J....Saeland S. (1994)
    140. A novel mutation in CD40 and its functional character ization. (PubMed id 19479954)1, 9 Qi C.J....Zhang X.G. (2009)
    141. CD40 signaling activated by Epstein-Barr virus promotes cell survival and proliferation in gastric carcinoma-derived human epithelial cells. (PubMed id 19397878)1, 9 Imadome K....Fujiwara S. (2009)
    142. The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes. (PubMed id 19183933)1, 9 Poggi M....Alessi M.C. (2009)
    143. Activation of human B cells by the agonist CD40 antib ody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulat ion. (PubMed id 19906293)1, 9 Carpenter E.L....Vonderheide R.H. (2009)
    144. C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells. (PubMed id 19171874)1, 9 Baruah P....Botto M. (2009)
    145. CD40/CD40L interaction induces Abeta production and i ncreases gamma-secretase activity independently of tumor necrosis factor recept or associated factor (TRAF) signaling. (PubMed id 19422822)1, 9 Volmar C.H....Mullan M.J. (2009)
    146. Characterization of natural human antagonistic soluble CD40 isoforms produced through alternative splicing. (PubMed id 18849075)1, 9 Eshel D....Douvdevani A. (2008)
    147. OK432-activated human dendritic cells kill tumor cells via CD40/CD40 ligand interactions. (PubMed id 18713981)1, 9 Hill K.S....Melcher A.A. (2008)
    148. Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease. (PubMed id 18835787)1, 9 Ait-ghezala G....Mullan M.J. (2008)
    149. Simvastatin reduces platelet-endocardium adhesion in atrial fibrillation. (PubMed id 17904146)1, 9 Chello M....Covino E. (2008)
    150. CD40 ligation decreases its protein half-life at the cell surface. (PubMed id 18253927)1, 9 Tucker T.A. and Schwiebert L.M. (2008)
    151. N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells. (PubMed id 18437082)1, 9 Vosters O....Verhasselt V. (2008)
    152. TACI attenuates antibody production costimulated by BAFF-R and CD40. (PubMed id 17154264)1, 9 Sakurai D....Kobata T. (2007)
    153. Effect of exogenous ghrelin on cell differentiation antigen 40 expression in endothelial cells. (PubMed id 18064390)1, 9 Zhang M....Fang W. (2007)
    154. CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets. (PubMed id 16936191)1, 9 Barbe-Tuana F.M....Pastori R.L. (2006)
    155. Chylomicron remnants upregulate CD40 expression via the ERK pathway and a redox-sensitive mechanism in THP-1 cells. (PubMed id 16356505)1, 9 Kamemura K....Yokoyama M. (2006)
    156. Nuclear localization in the biology of the CD40 receptor in normal and neoplastic human B lymphocytes. (PubMed id 16644731)1, 9 Lin-Lee Y.C....Ford R.J. (2006)
    157. Reduced radiosensitivity and increased CD40 expression in cyclophosphamide-resistant subclones established from human cervical squamous cell carcinoma cells. (PubMed id 16142355)1, 9 Tanaka T....Umesaki N. (2005)
    158. Retinoic acid inhibits CD40 plus IL-4 mediated IgE production through alterations of sCD23, sCD54 and IL-6 production. (PubMed id 15883744)1, 9 Scheffel F....Worm M. (2005)
    159. TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages. (PubMed id 15634933)1, 9 Mukundan L....Suttles J. (2005)
    160. Activation of mesangial cells by platelets in systemic lupus erythematosus via a CD154-dependent induction of CD40. (PubMed id 16221206)1, 9 Delmas Y....Ripoche J. (2005)
    161. Human immunodeficiency virus (HIV) type 1 Vpu induces the expression of CD40 in endothelial cells and regulates HIV-induced adhesion of B-lymphoma cells. (PubMed id 15078922)1, 9 Henderson W.W....Moses A.V. (2004)
    162. Effect of beta2-adrenergic receptor agonists on intercellular adhesion molecule (ICAM)-1, B7, and CD40 expression in mixed lymphocyte reaction. (PubMed id 14742996)1, 9 Tamura R....Tanaka N. (2004)
    163. Functional defects of dendritic cells in patients with CD40 deficiency. (PubMed id 12893749)1, 9 Fontana S....Badolato R. (2003)
    164. Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling. (PubMed id 14517219)1, 9 Li C....Ely K.R. (2003)
    165. Strong expression of CD40, CD54 and HLA-DR antigen and lack of evidence for direct cellular cytotoxicity are unique immunohistopathological features in alopecia areata. (PubMed id 12624779)1, 9 Sato-Kawamura M....Tagami H. (2003)
    166. CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis. (PubMed id 12637493)1, 9 Deregibus M.C....Camussi G. (2003)
    167. The selective triggering of CD40 on keratinocytes in vivo enhances cell-mediated immunity. (PubMed id 11870634)1, 9 Fuller B.W....Noelle R.J. (2002)
    168. CD40 on salivary gland epithelial cells: high constitutive expression by cultured cells from Sjogren's syndrome patients indicating their intrinsic activation. (PubMed id 11876766)1, 9 Dimitriou I.D....Manoussakis M.N. (2002)
    169. CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE. (PubMed id 12209089)1, 9 Zhang K....Saxon A. (2002)
    170. The serine protease plasmin triggers expression of MCP-1 and CD40 in human primary monocytes via activation of p38 MAPK and janus kinase (JAK)/STAT signaling pathways. (PubMed id 12093796)1, 9 Burysek L....Simmet T. (2002)
    171. CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells. (PubMed id 11997318)1, 9 Li H. and Nord E.P. (2002)
    172. CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. (PubMed id 12356871)1, 9 Becker T....Wieland F. (2002)
    173. Human lung myofibroblasts as effectors of the inflammatory process: the common receptor gamma chain is induced by Th2 cytokines, and CD40 ligand is induced by lipopolysaccharide, thrombin and TNF-alpha. (PubMed id 12207328)1, 9 Doucet C....Azzarone B. (2002)
    174. Characterization of a CD40-dominant inhibitory receptor mutant. (PubMed id 11714804)1, 9 Mehl A.M....Brennan P. (2001)
    175. Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling. (PubMed id 10748139)1, 9 Hostager B.S....Bishop G.A. (2000)
    176. TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation. (PubMed id 10764746)1, 9 Pype S.... Remacle J.E. (2000)
    177. CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway. (PubMed id 10601289)1, 9 Segui B....Levade T. (1999)
    178. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. (PubMed id 7859281)1, 9 Mosialos G....Kieff E. (1995)
    179. Autocrine TNF-a-mediated NF-kB activation is a determi nant for evasion of CD40-induced cytotoxicity in cancer cells. (PubMed id 23751348)1 Li D....Wang X. (2013)
    180. Infiltration of CD40-positive tumor-associated macroph ages indicates a favorable prognosis in colorectal cancer patients. (PubMed id 22687258)1 Kinouchi M....Unno M. (2013)
    181. Single nucleotide polymorphism of CD40 region and the risk of systemic lupus erythematosus. (PubMed id 23257401)1 Piotrowski P....Jagodzinski P.P. (2013)
    182. Cysteine-rich domain 1 of CD40 mediates receptor self- assembly. (PubMed id 23463508)1 Smulski C.R....Fournel S. (2013)
    183. CD40 signal regulates CXCR4 mediating ovarian carcinom a cell migration: implications for extrapelvic metastastic factors. (PubMed id 23924922)1 Qu Q.X....Zhang X.G. (2013)
    184. CD40-CD40L: linking pancreatic, adipose tissue and vas cular inflammation in type 2 diabetes and its complications. (PubMed id 22965071)1 Seijkens T....Lutgens E. (2013)
    185. Monocyte CD40 expression in head and neck squamous cel l carcinoma (HNSCC). (PubMed id 23000501)1 Sathawane D....Saha B. (2013)
    186. [The effect of genetic factors on the phenotypic expre ssion of multiple sclerosis]. (PubMed id 23528589)1 Korobko D.S....Filipenko M.L. (2013)
    187. Role of CD40 in prion disease and the immune response to recombinant PrP. (PubMed id 23419881)1 Rubenstein R....Wisniewski T. (2013)
    188. CD40 inhibits replication of hepatitis C virus in prim ary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway. (PubMed id 22814930)1 Rau S.J....Fischer R. (2013)
    189. CD40 induces anti-Toxoplasma gondii activity in nonhem atopoietic cells dependent on autophagy proteins. (PubMed id 23509150)1 Van Grol J....Subauste C.S. (2013)
    190. Bcl2-associated Athanogene 3 Interactome Analysis Reve als a New Role in Modulating Proteasome Activity. (PubMed id 23824909)1 Chen Y....Ge F. (2013)
    191. OTUD7B controls non-canonical NF-kB activation through deubiquitination of TRAF3. (PubMed id 23334419)1 Hu H....Sun S.C. (2013)
    192. Markers CD40, VEGF, AKT, PI3K, and S100 correlate with tumor stage in gastric cancer. (PubMed id 23429328)1 Tian W.Y....Liu L. (2013)
    193. Association of genetic polymorphisms in CD40 with susc eptibility to SLE in the Korean population. (PubMed id 23256180)1 Joo Y.B....Bae S.C. (2013)
    194. [The first results of a combined all-Russian study on clinical genetics of multiple sclerosis]. (PubMed id 23528588)1 Sokolova E.A....Filipenko M.L. (2013)
    195. CD40 mediates downregulation of CD32B on specific memo ry B cell populations in rheumatoid arthritis. (PubMed id 23686494)1 Zhang X....Strome S.E. (2013)
    196. Pentoxifylline decreases soluble CD40 ligand concentra tion and CD40 gene expression in coronary artery disease patients. (PubMed id 21999662)1 Shamsara J....Ramezani M. (2012)
    197. Monocyte-derived CD40 expression is regulated by inter feron-g/interferon-g receptor-1 pathway when acting as a bridge during their int eraction with T cells and allogeneic endothelial cells. (PubMed id 22564607)1 Zhu L.M....Xu H. (2012)
    198. Genetically driven target tissue overexpression of CD4 0: a novel mechanism in autoimmune disease. (PubMed id 22888137)1 Huber A.K....Tomer Y. (2012)
    199. Expression of CD40 and growth-inhibitory activity of C D40 agonist in ovarian carcinoma cells. (PubMed id 22406982)1 Zhou Y....Yang J.L. (2012)
    200. The interleukin-2 receptor a chain (CD25) plays an imp ortant role in regulating monocyte-derived CD40 expression during anti-porcine c ellular responses. (PubMed id 22564647)1 Sun Z.G....Xu H. (2012)
    201. Two new susceptibility loci for Kawasaki disease ident ified through genome-wide association analysis. (PubMed id 22446961)1 Lee Y.C....Wu J.Y. (2012)
    202. Activation of CD40 with platelet derived CD154 promote s reactive oxygen species dependent death of human hepatocytes during hypoxia an d reoxygenation. (PubMed id 22295117)1 Bhogal R.H....Afford S.C. (2012)
    203. CD40 C/T-1 polymorphism plays different roles in Grave s' disease and Hashimoto's thyroiditis: a meta-analysis. (PubMed id 22863718)1 Li M....Sun D. (2012)
    204. Polymorphisms of the genes encoding CD40 and growth di fferentiation factor 15 and in the 9p21.3 region in patients with rheumatoid art hritis and cardiovascular disease. (PubMed id 22505696)1 Arlestig L. and Rantapaa-Dahlqvist S. (2012)
    205. Expression of the co-signaling molecules CD40-CD40L an d their growth inhibitory effect on pancreatic cancer in vitro. (PubMed id 22552529)1 He S....Li D. (2012)
    206. Gene expression profiling indicates that immunohistoch emical expression of CD40 is a marker of an inflammatory reaction in the tumor s troma of diffuse large B-cell lymphoma. (PubMed id 22335531)1 Rydstrom K....Linderoth J. (2012)
    207. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    208. Influence of MIF, CD40, and CD226 polymorphisms on ris k of rheumatoid arthritis. (PubMed id 22302395)1 Liu R....Fan W. (2012)
    209. CD40 gene polymorphisms confer risk of Behcet's disease but not of Vogt-Koyanagi-Harada syndrome in a Han Chinese population. (PubMed id 22087016)1 Chen F....Yang P. (2012)
    210. Associations between autoimmune thyroid disease progno sis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, F CRL3, and ZFAT, previously revealed in genome-wide association studies. (PubMed id 22706687)1 Inoue N....Iwatani Y. (2012)
    211. Contribution of p38 MAPK, NF-kB and glucocorticoid sig naling pathways to ER stress-induced increase in retinal endothelial permeabilit y. (PubMed id 22310643)1 Adachi T....Hara H. (2012)
    212. Morphological characteristics and co-stimulatory molec ule (CD80, CD86, CD40) expression in tumor infiltrating dendritic cells in human endometrioid adenocarcinoma. (PubMed id 22142817)1 Jia J....Wang X. (2012)
    213. CD40 stimulation induces vincristine resistance via AK T activation and MRP1 expression in a human multiple myeloma cell line. (PubMed id 22445357)1 Lee S.W....Choi I. (2012)
    214. Critical role of CD40-mediated autocrine tumor necrosi s factor-alpha in potentiation of cisplatin-induced cytotoxicity in cancer cells . (PubMed id 22010829)1 Sun H....Wang X. (2012)
    215. Study of human B7 homolog 1 expression in patients wit h hepatitis B virus infection. (PubMed id 22851860)1 Zhang W.J....Zheng S.S. (2012)
    216. Aberrant CD40-induced NF-kB activation in human lupus B lymphocytes. (PubMed id 22952582)1 Zhang W....He W. (2012)
    217. The CD40-CD40L axis and IFN-g play critical roles in L anghans giant cell formation. (PubMed id 22058328)1 Sakai H....Heike T. (2012)
    218. CD40-mediated cell death requires TRAF6 recruitment. (PubMed id 21813202)1 Jundi M....Mourad W. (2012)
    219. The involvement of the CD40-CD40L pathway in activated platelet-induced changes in HUVEC COX-2 and PPARa expression. (PubMed id 22219050)1 Wu Y.Q....Chai J.B. (2012)
    220. Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-kB. (PubMed id 23092922)1 Gillespie E.F....Douglas R.S. (2012)
    221. CD40/CD154 blockade inhibits dendritic cell expression of inflammatory cytokines but not costimulatory molecules. (PubMed id 23002440)1 Ferrer I.R....Ford M.L. (2012)
    222. CD40 C/T(-1) and CTLA-4 A/G(49) SNPs are associated wi th autoimmune thyroid diseases in the Chinese population. (PubMed id 21866398)1 Yang J....Zhang J.A. (2012)
    223. Study of association of CD40-CD154 gene polymorphisms with disease susceptibility and cardiovascular risk in Spanish rheumatoid arthri tis patients. (PubMed id 23166616)1 Garcia-Bermudez M....Gonzalez-Gay M.A. (2012)
    224. CD40 signal expression in gastric cancer tissue and it s correlation with prognosis of gastric cancer patients. (PubMed id 22722990)1 Li R....Zhang X.G. (2012)
    225. CD40, CD45 CTLA-4 levels are elevated in healthy older adults. (PubMed id 22783574)1 Yalcin A.D....Terzioglu E. (2012)
    226. Investigation of the interaction between the MIR-503 a nd CD40 genes in irradiated U937 cells. (PubMed id 22429276)1 Cheng G....Jin S. (2012)
    227. Evaluation of CD40, its ligand CD40L and Bcl-2 in psor iatic patients. (PubMed id 22532139)1 Mysliwiec H....Chodynicka B. (2012)
    228. The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes. (PubMed id 22558273)1 Renga B....Fiorucci S. (2012)
    229. CD40 Gene polymorphisms associated with susceptibility and coronary artery lesions of Kawasaki disease in the Taiwanese population. (PubMed id 22645426)1 Kuo H.C....Wang C.L. (2012)
    230. The germinal center kinase TNIK is required for canoni cal NF-kB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. (PubMed id 22904686)1 Shkoda A....Kieser A. (2012)
    231. CD40 stimulates a 'feed-forward' NF-kB-drive n molecular pathway that regulates IFN-b expression in carcinoma cells. (PubMed id 22547704)1 Moschonas A....Eliopoulos A.G. (2012)
    232. Involvement of nuclear factor kB in platelet CD40 sign aling. (PubMed id 22820189)1 Hachem A....Merhi Y. (2012)
    233. Analysis of the association between CD40 and CD40 liga nd polymorphisms and systemic sclerosis. (PubMed id 22731751)1 Teruel M....Martin J. (2012)
    234. Functional interaction of CD154 protein with a5b1 inte grin is totally independent from its binding to aIIbb3 integrin and CD40 molecul es. (PubMed id 22461623)1 El Fakhry Y....Mourad W. (2012)
    235. A common SNP in the CD40 region is associated with sy stemic lupus erythematosus and correlates with altered CD40 expression: implica tions for the pathogenesis. (PubMed id 21914625)1 Vazgiourakis V.M....Goulielmos G.N. (2011)
    236. A CD40 single-nucleotide polymorphism affects the lymp hocyte profiles in the bronchoalveolar lavage of Japanese patients with sarcoido sis. (PubMed id 22077624)1 Tanizawa K....Izumi T. (2011)
    237. Toll-like receptor 9, transmembrane activator and cal cium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B- cell activation. (PubMed id 21741080)1 Ozcan E....Geha R.S. (2011)
    238. CD40 translocation to lipid rafts: signaling requirem ents and downstream biological events. (PubMed id 21567389)1 Nadiri A....Mourad W. (2011)
    239. Crystallographic and mutational analysis of the CD40- CD154 complex and its implications for receptor activation. (PubMed id 21285457)1 An H.J....Lee H. (2011)
    240. Tyrosine nitration limits stretch-induced CD40 expres sion and disconnects CD40 signaling in human endothelial cells. (PubMed id 21832282)1 Wagner A.H....Hecker M. (2011)
    241. Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence. (PubMed id 21922073)1 Tokarev A. and Guatelli J. (2011)
    242. Ligation of CD40 receptor in human B lymphocytes trig gers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK. (PubMed id 21200133)1 Ha Y.J....Lee J.R. (2011)
    243. Genome-wide meta-analysis identifies novel multiple sc lerosis susceptibility loci. (PubMed id 22190364)1 Patsopoulos Bakker P.I. (2011)
    244. Sensitization of SiHa cell to gemcitabine by CD40 act ivation and its overexpression in cervical carcinoma. (PubMed id 20467921)1 Huang Q....Zhang X.G. (2011)
    245. The CD40 gene polymorphism rs1883832 is associated wi th risk of acute coronary syndrome in a Chinese case-control study. (PubMed id 21091218)1 Wang M....Wu Q. (2011)
    246. CTSS activation coexists with CD40 activation in huma n atheroma: evidence from plasma mRNA analysis. (PubMed id 21223957)1 Cerne D....Kranjec I. (2011)
    247. A composite MyD88/CD40 switch synergistically activat es mouse and human dendritic cells for enhanced antitumor efficacy. (PubMed id 21383499)1 Narayanan P....Spencer D.M. (2011)
    248. The CD40-CD154 interaction would correlate with proli feration and immune escape in pancreatic ductal adenocarcinoma. (PubMed id 21337550)1 Shoji Y....Kondo S. (2011)
    249. CD40L-containing virus-like particle as a candidate HI V-1 vaccine targeting dendritic cells. (PubMed id 21239998)1 Franco D....Ho D.D. (2011)
    250. A CD40 and an NCOA5 gene polymorphism confer suscepti bility to psoriasis in a Southern European population: a case-control study. (PubMed id 21645569)1 Zervou M.I....Krueger-Krasagakis S. (2011)
    251. Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)1  ....Compston A. (2011)
    252. The death domain kinase RIP1 links the immunoregulato ry CD40 receptor to apoptotic signaling in carcinomas. (PubMed id 21282461)1 Knox P.G....Eliopoulos A.G. (2011)
    253. CD40 stimulation sensitizes CLL cells to rituximab-in duced cell death. (PubMed id 21403646)1 Jak M....van Oers M.H. (2011)
    254. CD40 polymorphisms in Han Chinese patients with Fuch uveitis syndrome. (PubMed id 21976957)1 Chen F....Yang P. (2011)
    255. CD40/CD40L interaction induces E-selectin dependent l eukocyte adhesion to human endothelial cells and inhibits endothelial cell migr ation. (PubMed id 21138731)1 Urban D....Stawowy P. (2011)
    256. PPARI^ expression is increased in systemic lupus eryth ematosus patients and represses CD40/CD40L signaling pathway. (PubMed id 21415255)1 Oxer D.S....Souza H.P. (2011)
    257. Association of CD40 gene polymorphisms with sporadic breast cancer in Chinese Han women of Northeast China. (PubMed id 21912605)1 Shuang C....Li D. (2011)
    258. The role of rheumatoid arthritis genetic susceptibili ty markers in the prediction of erosive disease in patients with early inflamma tory polyarthritis: results from the Norfolk Arthritis Register. (PubMed id 20219786)1 Plant D....Barton A. (2010)
    259. Primary and malignant cholangiocytes undergo CD40 med iated Fas dependent apoptosis, but are insensitive to direct activation with ex ogenous Fas ligand. (PubMed id 21103345)1 Humphreys E.H....Afford S.C. (2010)
    260. Different molecular behavior of CD40 mutants causing hyper-IgM syndrome. (PubMed id 20702779)1 Lanzi G....Giliani S. (2010)
    261. Association between serum levels of soluble CD40/CD40 ligand and organ damage in hypertensive patients. (PubMed id 20456428)1 Yuan M....Ren J. (2010)
    262. Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients. (PubMed id 20368992)1 Jensen C.J....Butzkueven H. (2010)
    263. The transmembrane activator TACI triggers immunoglobu lin class switching by activating B cells through the adaptor MyD88. (PubMed id 20676093)1 He B....Cerutti A. (2010)
    264. CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells. (PubMed id 20081875)1 Zheng J....Tu W. (2010)
    265. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    266. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    267. CD40 is a potential marker of favorable prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy. (PubMed id 20593977)1 RydstrAPm K....Jerkeman M. (2010)
    268. CD40 expression by human melanocytic lesions and mela noma cell lines and direct CD40 targeting with the therapeutic anti-CD40 antibo dy CP-870,893. (PubMed id 20842056)1 Kalbasi A....Ribas A. (2010)
    269. Enhanced levels of soluble CD40 ligand exacerbate pla telet aggregation and thrombus formation through a CD40-dependent tumor necrosi s factor receptor-associated factor-2/Rac1/p38 mitogen-activated protein kinase signaling pathway. (PubMed id 21071692)1 Yacoub D....Merhi Y. (2010)
    270. Association analysis of CD40 gene polymorphism with a cute coronary syndrome. (PubMed id 20127135)1 Yan J....Chen G. (2010)
    271. CD40 signalling induces IL-10-producing, tolerogenic dendritic cells. (PubMed id 19889024)1 Tuettenberg A....Jonuleit H. (2010)
    272. Differential TRAF3 utilization by a variant human CD4 0 receptor with enhanced signaling. (PubMed id 21041727)1 Peters A.L. and Bishop G.A. (2010)
    273. Pollen-induced oxidative stress influences both innat e and adaptive immune responses via altering dendritic cell functions. (PubMed id 20118277)1 Csillag A....Bacsi A. (2010)
    274. Gene-gene interaction between CD40 and CD40L reduces bone mineral density and increases osteoporosis risk in women. (PubMed id 20577873)1 Pineda B....GarcA-a-PAcrez M.A. (2010)
    275. Impact of residual renal function and HCV seropositiv ity on plasma CD40/CD40L system and oxidative status in haemodialysis patients. (PubMed id 20846521)1 Pawlak K....Pawlak D. (2010)
    276. Flow cytometric investigation of CD40-CD40 ligand sys tem in preeclampsia and normal pregnancy. (PubMed id 19221099)1 Lukanov T.H....Konova E.I. (2010)
    277. MS80, a novel sulfated polysaccharide, inhibits CD40- NF-kappaB pathway via targeting RIP2. (PubMed id 19911254)1 Du X....Jiang H. (2010)
    278. Lycorine sensitizes CD40 ligand-protected chronic lym phocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistan ce. (PubMed id 20634492)1 Hayden R.E....Bunce C.M. (2010)
    279. CD40 -1C>T single nucleotide polymorphism and CD40 expression on breast tumors. (PubMed id 20371189)1 Dolen Y....Guc D. (2010)
    280. Analysis of Immune Regulatory Genes' Copy Number Vari ants in Graves' Disease. (PubMed id 21054240)1 Huber A.K....Tomer Y. (2010)
    281. The expression of intercellular adhesion molecule-1 i nduced by CD40-CD40L ligand signaling in orbital fibroblasts in patients with G raves' ophthalmopathy. (PubMed id 20107176)1 Zhao L.Q....Li Y. (2010)
    282. HOIL-1L interacting protein (HOIP) as an NF-kappaB reg ulating component of the CD40 signaling complex. (PubMed id 20614026)1 Hostager B.S....Colgan J.D. (2010)
    283. Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheuma toid arthritis in African Americans. (PubMed id 21120996)4 Hughes L.B....Bridges S.L. (2010)
    284. Up-regulation of the expression of costimulatory mole cule CD40 in hepatocytes by hepatitis B virus X antigen. (PubMed id 19336218)1 Tang Y....Wu Y. (2009)
    285. Inhibition of lung cancer cell proliferation by CD40 signaling through tumor necrosis factor I. (PubMed id 19448410)1 Lu X.D....Huang J.A. (2009)
    286. Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting. (PubMed id 19023113)1 Longo N.S....Lipsky P.E. (2009)
    287. HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr). (PubMed id 19275586)1 Majumder B....Ayyavoo V. (2009)
    288. Interactions of viral protein U (Vpu) with cellular fa ctors. (PubMed id 20012522)1 Guatelli J.C. (2009)
    289. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    290. CD40 and B-cell receptor signalling induce MAPK family members that can either induce or repress Bcl-6 expression. (PubMed id 19268365)1 Batlle A....Wagner S.D. (2009)
    291. Anthocyanin attenuates CD40-mediated endothelial cell activation and apoptosis by inhibiting CD40-induced MAPK activation. (PubMed id 18495129)1 Xia M....Ye Q. (2009)
    292. Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas. (PubMed id 19475450)1 Mees S.T....Haier J. (2009)
    293. CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion. (PubMed id 19002156)1 Carreno B.M....Linette G.P. (2009)
    294. Human immunodeficiency virus type 1 Vpr: functions and molecular interactions. (PubMed id 19458171)1 Romani B. and Engelbrecht S. (2009)
    295. Disease activity in systemic lupus erythematosus is a ssociated with an altered expression of low-affinity Fc gamma receptors and cos timulatory molecules on dendritic cells. (PubMed id 20067533)1 CarreA+o L.J....Kalergis A.M. (2009)
    296. Impact of CD40 expression by flowcytometry on outcome of patients with non-Hodgkin's lymphoma. (PubMed id 20726323)1 Soliman M.A....El-Bassal F. (2009)
    297. Elevated plasma levels of soluble CD40 in incipient Alzheimer's disease. (PubMed id 18996438)1 Buchhave P....Hansson O. (2009)
    298. Fas apoptosis inhibitory molecule enhances CD40 signa ling in B cells and augments the plasma cell compartment. (PubMed id 19592656)1 Kaku H. and Rothstein T.L. (2009)
    299. Upregulation of the CD40-CD40 ligand system in pre-ec lampsia. (PubMed id 19272596)1 Lukanov T.H....Konova E.I. (2009)
    300. [Expression of CD40 in human gastric cancer tissue an d its prognostic correlation] (PubMed id 20058617)1 Li R....Zhang X.G. (2009)
    301. Expression of the Bcl-2 protein BAD promotes prostate cancer growth. (PubMed id 19593445)1 Smith A.J....Kulik G. (2009)
    302. Interferon-beta therapy up-regulates BDNF secretion f rom PBMCs of MS patients through a CD40-dependent mechanism. (PubMed id 19419774)1 Azoulay D....Karni A. (2009)
    303. c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. (PubMed id 18796631)1 Hallaert D.Y....Eldering E. (2008)
    304. Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells. (PubMed id 18487509)1 Polo J.M....Melnick A. (2008)
    305. Analysis of 45 candidate genes for disease modifying a ctivity in multiple sclerosis. (PubMed id 18563468)4 Ramagopalan S.V....Ebers G.C. (2008)
    306. Distinct effect of CD40 and TNF-signaling on the chemokine/chemokine receptor expression and function of the human monocyte-derived dendritic cells. (PubMed id 18445342)1 Xia Y....Zhang X. (2008)
    307. Relationship between the serum sCD40L level and aspirin-resistant platelet aggregation in patients with stable coronary artery disease. (PubMed id 18159101)1 Pamukcu B....Nisanci Y. (2008)
    308. A C >T polymorphism located at position -1 of the Kozak sequence of CD40 gene is associated with low bone mass in Spanish postmenopausal women. (PubMed id 18097708)1 Pineda B....GarcA-a-PAcrez M.A. (2008)
    309. Expression of CD40 in ovarian cancer and adenovirus-mediated CD40 ligand therapy on ovarian cancer in vitro. (PubMed id 18705404)1 Jiang E....Zhao X. (2008)
    310. CD40 ligand protects from TRAIL-induced apoptosis in follicular lymphomas through NF-kappaB activation and up-regulation of c-FLIP and Bcl-xL. (PubMed id 18606651)1 Travert M....Guillaudeux T. (2008)
    311. A novel polymorphism of the human CD40 receptor with enhanced function. (PubMed id 18591382)1 Peters A.L....Bishop G.A. (2008)
    312. TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation. (PubMed id 17599408)1 Merluzzi S....Pucillo C. (2008)
    313. Neutrophil CD40 enhances platelet-mediated inflammation. (PubMed id 18289643)1 Vanichakarn P....Chakrabarti S. (2008)
    314. CD4+T cells in CIKs (CD4+ CIKs) reversed resistance to fas-mediated apoptosis through CD40/CD40L ligation rather than IFN-gamma stimulation. (PubMed id 18593367)1 Yu J....Ren X. (2008)
    315. CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis. (PubMed id 17989345)1 Nolan A....Gold J.A. (2008)
    316. CD40-CD40 ligand interactions in human microglia induc e CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1 /2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator p rotein-1 (AP-1). (PubMed id 17918746)1 D'Aversa T.G....Berman J.W. (2008)
    317. CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling. (PubMed id 18669876)1 Pluvinet R....Aran J.M. (2008)
    318. [A study of costimulatory molecules in allergic allergic rhinitis patients] (PubMed id 19086656)1 Zhu R....Zhang W. (2008)
    319. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo. (PubMed id 19018001)1 Dormond O....Briscoe D.M. (2008)
    320. Relationship between upregulation of CD40 system and restenosis in patients after percutaneous coronary intervention. (PubMed id 17302995)1 Yan J.C....Luo D. (2007)
    321. High expression of CD40 on skin fibroblasts from pati ents with systemic sclerosis. (PubMed id 17687557)1 Jun J.B....Yoo D.H. (2007)
    322. Monocytes are activated in patients with myelodysplastic syndromes and can contribute to bone marrow failure through CD40-CD40L interactions with T helper cells. (PubMed id 17805323)1 Meers S....Delforge M. (2007)
    323. Monocyte-derived dendritic cells of patients with coronary artery disease show an increased expression of costimulatory molecules CD40, CD80 and CD86 in vitro. (PubMed id 17925605)1 Dopheide J.F....Blankenberg S. (2007)
    324. Soluble CD40 and its ligand CD154 in patients with Graves' ophthalmopathy during combined therapy with corticosteroids and teleradiotherapy. (PubMed id 18217399)1 Mysliwiec J....Gorska M. (2007)
    325. Expression of RANTES and MCP-1 in epithelial cells is regulated via LMP1 and CD40. (PubMed id 17721998)1 Buettner M....Niedobitek G. (2007)
    326. Cooperativity in the interaction of synthetic CD40L mimetics with CD40 and its implication in cell signaling. (PubMed id 17319699)1 Wieckowski S....Hoebeke J. (2007)
    327. C4b binding protein binds to CD154 preventing CD40 mediated cholangiocyte apoptosis: a novel link between complement and epithelial cell survival. (PubMed id 17225862)1 Williams K.T....Afford S.C. (2007)
    328. Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. (PubMed id 16806233)1 Ma J....Liew C.C. (2007)
    329. CD40 ligand-mediated activation of the de novo RelB NF-kappaB synthesis pathway in transformed B cells promotes rescue from apoptosis. (PubMed id 17446175)1 Mineva N.D....Sonenshein G.E. (2007)
    330. Association between circulating level of CD40 ligand and angiographic morphologic features indicating high-burden thrombus formation in patients with acute myocardial infarction undergoing primary coronary intervention. (PubMed id 18037736)1 Youssef A.A....Yip H.K. (2007)
    331. A costimulatory function for T cell CD40. (PubMed id 17202327)1 Munroe M.E. and Bishop G.A. (2007)
    332. Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B. (PubMed id 17878343)1 Qiao G....Zhang J. (2007)
    333. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes. (PubMed id 18045485)4 Cooper J.D....Todd J.A. (2007)
    334. Functional synergy between CD40 ligand and HIV-1 Tat c ontributes to inflammation: implications in HIV type 1 dementia. (PubMed id 17312171)1 Sui Z....Maggirwar S.B. (2007)
    335. The CD40-induced protection against CD95-mediated apoptosis is associated with a rapid upregulation of anti-apoptotic c-FLIP. (PubMed id 16901543)1 Eeva J....Pelkonen J. (2007)
    336. sCD40 ligand determined in maternal and umbilical cord blood in pregnancies complicated by pre-eclampsia with and without intrauterine growth retardation. (PubMed id 17199090)1 Laskowska M....Oleszczuk J. (2007)
    337. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    338. Lipid rafts regulate cellular CD40 receptor localization in vascular endothelial cells. (PubMed id 17678876)1 Xia M....Ling W. (2007)
    339. CD40-40L signaling in vascular inflammation. (PubMed id 17459878)1 Chakrabarti S....Freedman J.E. (2007)
    340. Up-regulation of c-FLIPS+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL. (PubMed id 17376892)1 Troeger A....Dilloo D. (2007)
    341. CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. (PubMed id 16357329)1 von Bergwelt-Baildon M....Schultze J.L. (2006)
    342. Giving blood: a new role for CD40 in tumorigenesis. (PubMed id 17043147)1 Bergmann S. and Pandolfi P.P. (2006)
    343. CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system. (PubMed id 16893496)1 Chen K....Wang J.M. (2006)
    344. Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia. (PubMed id 17012138)1 Luomala M....Lehtimaki T. (2006)
    345. [Serum levels and clinical significance of soluble CD40 in liver disease] (PubMed id 17077013)1 Liu H....Zhang X.G. (2006)
    346. Circulating CD40 ligand is elevated only in patients with more advanced symptomatic peripheral arterial diseases. (PubMed id 16356539)1 Lee W.J....Lee W.L. (2006)
    347. CD40/CD40 ligand signaling in mouse cerebral microvasculature after focal ischemia/reperfusion. (PubMed id 15795333)1 Ishikawa M....Granger D.N. (2005)
    348. Constitutive activation of the CD40 pathway promotes cell transformation and neoplastic growth. (PubMed id 16091748)1 Baxendale A.J....Eliopoulos A.G. (2005)
    349. Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L. (PubMed id 16213477)1 Lee J.K....Wiltrout R.H. (2005)
    350. Thyroid cancers express CD-40 and CD-40 ligand: cancers that express CD-40 ligand may have a greater risk of recurrence in young patients. (PubMed id 15753667)1 Costello A....Francis G.L. (2005)
    351. Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways. (PubMed id 15749123)1 Chen W....Pomerantz R.J. (2005)
    352. T cells from paroxysmal nocturnal haemoglobinuria (PNH) patients show an altered CD40-dependent pathway. (PubMed id 15817705)1 Terrazzano G....Ruggiero G. (2005)
    353. Fas-ligand (CD178) and TRAIL synergistically induce apoptosis of CD40-activated chronic lymphocytic leukemia B cells. (PubMed id 15339846)1 Dicker F....Kipps T.J. (2005)
    354. Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets. (PubMed id 15808676)1 Mai G....Buhler L.H. (2005)
    355. Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40. (PubMed id 15994291)1 de Goer de Herve M.G....Taoufik Y. (2005)
    356. Biotinylation of heat shock protein 70 induces RANTES production in HEK293 cells in a CD40-independent pathway. (PubMed id 16246299)1 Tao Y....Tani F. (2005)
    357. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
    358. HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro. (PubMed id 15611322)1 Muthumani K....Weiner D.B. (2005)
    359. Tracking CD40 signaling during germinal center development. (PubMed id 15331443)1 Basso K....Dalla-Favera R. (2004)
    360. Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells. (PubMed id 15113760)1 Luft T....Bierhaus A. (2004)
    361. Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma. (PubMed id 15069543)1 Suzuki O....Abe M. (2004)
    362. Signaling and protein associations of a cell permeable CD40 complex in B cells. (PubMed id 14644094)1 Zoog S.J....Kehry M.R. (2004)
    363. Prognostic value of CD40 in adult soft tissue sarcomas. (PubMed id 15102691)1 Ottaiano A....Apice G. (2004)
    364. Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation. (PubMed id 15578091)1 Jain A....Derry J.M. (2004)
    365. [Immune dysfuntion of uremic patients: potential role for the soluble form of CD40] (PubMed id 15291139)1 Contin C....Merville P. (2004)
    366. Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplification. (PubMed id 14764664)1 Danese S....Fiocchi C. (2004)
    367. CD40 activation of BCP-ALL cells generates IL-10-producing, IL-12-defective APCs that induce allogeneic T-cell anergy. (PubMed id 15001471)1 D'Amico G....Biondi A. (2004)
    368. Role of the CD40 locus in Graves' disease. (PubMed id 15307939)1 Houston F.A....Pearce S.H. (2004)
    369. Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor. (PubMed id 14747545)1 D'Souza B.N....Walls D. (2004)
    370. CD154/CD40-mediated expression of CD154 in endothelial cells: consequences for endothelial cell-monocyte interaction. (PubMed id 14976003)1 Wagner A.H....Hecker M. (2004)
    371. Functional caveolae are a prerequisite for CD40 signaling in human renal proximal tubule cells. (PubMed id 14665433)1 Li H. and Nord E.P. (2004)
    372. The human antibody response to pneumococcal capsular polysaccharides is dependent on the CD40-CD40 ligand interaction. (PubMed id 14991615)1 Jeurissen A....Bossuyt X. (2004)
    373. CD40 expression in prostate cancer: a potential diagnostic and therapeutic molecule. (PubMed id 15375484)1 Palmer D.H....James N.D. (2004)
    374. The CD40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves Ras and phosphatidylinositol 3-kinase. (PubMed id 15187129)1 Flaxenburg J.A....Pal S. (2004)
    375. The role of CD40-CD154 interaction in cell immunoregulation. (PubMed id 15153777)1 Xu Y. and Song G. (2004)
    376. Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. (PubMed id 15485634)1 Qian Y....Li X. (2004)
    377. Kinetics and signaling requirements of CD40-mediated protection from B cell receptor-induced apoptosis. (PubMed id 14515262)1 Eeva J....Pelkonen J. (2003)
    378. CD40 ligand trimer enhances the response of CD8+ T cells to Mycobacterium tuberculosis. (PubMed id 12626576)1 Samten B....Barnes P.F. (2003)
    379. Upregulation of CD40-CD40 ligand (CD154) in patients with acute cerebral ischemia. (PubMed id 12764232)1 Garlichs C.D....Daniel W.G. (2003)
    380. Differential regulation of cell survival by CD40. (PubMed id 12510151)1 Dallman C....Packham G. (2003)
    381. Differential induction of nuclear factor-kappaB and activator protein-1 activity after CD40 ligation is associated with primary human hepatocyte apoptosis or intrahepatic endothelial cell proliferation. (PubMed id 12686591)1 Ahmed-Choudhury J....Choudhury J.A. (2003)
    382. Disseminated cryptosporidium infection in an infant with hyper-IgM syndrome caused by CD40 deficiency. (PubMed id 12584544)1 Kutukculer N....Notarangelo L.D. (2003)
    383. Recent advances on the role of CD40 and dendritic cells in immunity and tolerance. (PubMed id 12799532)1 O'Sullivan B. and Thomas R. (2003)
    384. CD40 stimulation of human peripheral B lymphocytes: distinct response from naive and memory cells. (PubMed id 14568936)1 Fecteau J.F. and Neron S. (2003)
    385. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1 Matsuda A....Sugano S. (2003)
    386. Major involvement of CD40 in the regulation of chemokine secretion from human peritoneal mesothelial cells. (PubMed id 14633128)1 Man L....Douvdevani A. (2003)
    387. Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. (PubMed id 14617752)1 Grammer A.C....Lipsky P.E. (2003)
    388. CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium. (PubMed id 12507785)1 Omari K.M. and Dorovini-Zis K. (2003)
    389. CD40 can costimulate human memory T cells and favors IL-10 secretion. (PubMed id 12672076)1 Rogers N.J....Lechler R.I. (2003)
    390. Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis. (PubMed id 12905492)1 Clayton A.R....Savage C.O. (2003)
    391. CD40-dependent and -independent activation of human tonsil B cells by CpG oligodeoxynucleotides. (PubMed id 12778475)1 Gantner F....Bacon K.B. (2003)
    392. Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis. (PubMed id 12855571)1 Zazzeroni F....Franzoso G. (2003)
    393. Proangiogenic function of CD40 ligand-CD40 interactions. (PubMed id 12874247)1 Reinders M.E....Briscoe D.M. (2003)
    394. Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40-mediated interleukin-12 synthesis in human endothelial cells. (PubMed id 12857749)1 Cattaruzza M....Hecker M. (2003)
    395. CD40 triggering enhances fludarabine-induced apoptosis of chronic lymphocytic leukemia B-cells through autocrine release of tumor necrosis factor-alpha and interferon-gama and tumor necrosis factor receptor-I-II upregulation. (PubMed id 12604404)1 de Totero D....Gobbi M. (2003)
    396. Significance of chemokines and soluble CD40 ligand in patients with autoimmune thrombocytopenic purpura. (PubMed id 12460235)1 Nagahama M....Fukuhara S. (2002)
    397. CD40-mediated tumor necrosis factor receptor-associated factor 3 signaling upregulates IL-4-induced germline Cepsilon transcription in a human B cell line. (PubMed id 12220533)1 Basaki Y....Yanagihara Y. (2002)
    398. Ceramide-rich membrane rafts mediate CD40 clustering. (PubMed id 11751974)1 Grassme H....Gulbins E. (2002)
    399. Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia. (PubMed id 11891278)1 Chu P....Kipps T.J. (2002)
    400. Distinct molecular mechanism for initiating TRAF6 signalling. (PubMed id 12140561)1 Ye H.... Wu H. (2002)
    401. Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax. (PubMed id 12070030)1 Szocinski J.L....Murphy W.J. (2002)
    402. Clustering of CD40 ligand is required to form a functional contact with CD40. (PubMed id 12011072)1 Grassme H....Gulbins E. (2002)
    403. A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease. (PubMed id 12593727)1 Tomer Y....Greenberg D.A. (2002)
    404. Differential involvement of CD40, CD80, and major histocompatibility complex class I molecules in cytotoxicity induction and interferon-gamma production by human natural killer effectors. (PubMed id 12149421)1 Terrazzano G....Ruggiero G. (2002)
    405. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    406. Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals. (PubMed id 11867568)1 Yasui T....Kikutani H. (2002)
    407. CD40 ligation and phagocytosis differently affect the differentiation of monocytes into dendritic cells. (PubMed id 12488500)1 Rosenzwajg M....Gluckman J.C. (2002)
    408. Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. (PubMed id 11751963)1 Fanales-Belasio E....Ensoli B. (2002)
    409. Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. (PubMed id 11877469)1 Erickson L.D....Noelle R.J. (2002)
    410. CD40 ligation-induced cytokine production in human sk in explants is partly mediated via IL-1. (PubMed id 12039918)1 Companjen A.R....Laman J.D. (2002)
    411. Efficient generation of antigen-specific cytotoxic T cells using retrovirally transduced CD40-activated B cells. (PubMed id 12165546)1 Kondo E....Akatsuka Y. (2002)
    412. Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells. (PubMed id 12089335)1 Qian Y....Li X. (2002)
    413. CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. (PubMed id 12324477)1 Hase H....Kobata T. (2002)
    414. CD40 signaling and autoimmunity. (PubMed id 11826760)1 Cheng G. and Schoenberger S.P. (2002)
    415. CD40/CD40 ligand interactions in the host defense against disseminated Candida albicans infection: the role of macrophage-derived nitric oxide. (PubMed id 11981834)1 Netea M.G....Kullberg B.J. (2002)
    416. Human B cell activation by autologous NK cells is regulated by CD40-CD40 ligand interaction: role of memory B cells and CD5+ B cells. (PubMed id 11714772)1 Blanca I.R....Ortaldo J.R. (2001)
    417. The Common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism. (PubMed id 11160013)1 Ulanova M....Hanson L.A. (2001)
    418. CD40 ligation induces macrophage IL-10 and TNF-alpha production: differential use of the PI3K and p42/44 MAPK-pathways. (PubMed id 11792123)1 Foey A.D....Brennan F.M. (2001)
    419. A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains. (PubMed id 11279055)1 Zapata J.M....Reed J.C. (2001)
    420. CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes. (PubMed id 11817328)1 Bhushan A. and Covey L.R. (2001)
    421. Interleukin-12 counterbalances the deleterious effect of human immunodeficiency virus type 1 envelope glycoprotein gp120 on the immune response to Cryptococcus neoformans. (PubMed id 11087201)1 Pietrella D....Vecchiarelli A. (2001)
    422. Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNA. (PubMed id 11268217)1 Siddiqa A.... Martinez-Valdez H. (2001)
    423. Chemokines and CD40 expression in human fibroblasts. (PubMed id 10741409)1 Brouty-Boye D....Azzarone B. (2000)
    424. CD40-CD40 ligand. (PubMed id 10647992)1 van Kooten C. and Banchereau J. (2000)
    425. Identification of mature and immature human thymic dendritic cells that differentially express HLA-DR and interleukin-3 receptor in vivo. (PubMed id 11129651)1 Schmitt C....Dalloul A.H. (2000)
    426. Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2. (PubMed id 10847592)1 Lee S.K....Lee J.W. (2000)
    427. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. (PubMed id 10600748)1 Tan J....Mullan M. (1999)
    428. Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb. (PubMed id 10514012)1 Morio T....Yata J. (1999)
    429. Activation of the Janus kinase 3-STAT5a pathway after CD40 triggering of human monocytes but not of resting B cells. (PubMed id 10395671)1 Revy P....Durandy A. (1999)
    430. CD20 is physically and functionally coupled to MHC class II and CD40 on human B cell lines. (PubMed id 9933087)1 Leveille C....Mourad W. (1999)
    431. Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif. (PubMed id 10075662)1 Darnay B.G....Aggarwal B.B. (1999)
    432. Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation. (PubMed id 10352240)1 Hostager B.S. and Bishop G.A. (1999)
    433. Crystallographic analysis of CD40 recognition and signaling by human TRAF2. (PubMed id 10411888)1 McWhirter S.M....Alber T. (1999)
    434. Differential effects of CD40 ligand/trimer stimulation on the ability of dendritic cells to replicate and transmit HIV infection: evidence for CC-chemokine-dependent and -independent mechanisms. (PubMed id 10092834)1 McDyer J.F....Seder R.A. (1999)
    435. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. (PubMed id 9671306)1 Mach F....Libby P. (1998)
    436. RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. (PubMed id 9642260)1 McCarthy J.V.... Dixit V.M. (1998)
    437. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. (PubMed id 9624004)1 Bennett S.R....Heath W.R. (1998)
    438. CD40 is a functional activation antigen and B7-independent T cell costimulatory molecule on normal human lung fibroblasts. (PubMed id 9144479)1 Sempowski G.D....Phipps R.P. (1997)
    439. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. (PubMed id 9020361)1 Malinin N.L.... Wallach D. (1997)
    440. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. (PubMed id 9384571)1 Roy N....Reed J.C. (1997)
    441. Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily. (PubMed id 9168896)1 Boucher L.-M.... Mak T.W. (1997)
    442. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. (PubMed id 9050882)1 Mach F....Libby P. (1997)
    443. TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. (PubMed id 8790348)1 Ishida T.K....Inoue J. (1996)
    444. The human CD40 gene lies within chromosome 20q deletions associated with myeloid malignancies. (PubMed id 8562382)1 Asimakopoulos F.A....Green A.R. (1996)
    445. Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. (PubMed id 8906799)1 Okura T....Yeh E.T. (1996)
    446. Cleavage of membrane-bound CD40 ligand is not required for inducing B cell proliferation and differentiation. (PubMed id 8605945)1 Pietravalle F....Gauchat J.F. (1996)
    447. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. (PubMed id 7538666)1 Karmann K....Pober J.S. (1995)
    448. Localization of the human CD40 gene to chromosome 20, bands q12-q13.2. (PubMed id 7518550)1 Lafage-Pochitaloff M....Banchereau J. (1994)
    449. A novel RING finger protein interacts with the cytoplasmic domain of CD40. (PubMed id 7527023)1 Hu H.M.... Dixit V.M. (1994)
    450. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. (PubMed id 7516405)1 Foy T.M....Noelle R.J. (1994)
    451. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
    452. CD40: a cytokine receptor in search of a ligand. (PubMed id 1701063)1 Clark E.A. (1990)
    453. Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40. (PubMed id 2463309)2 Braesch-Andersen S....Perlmann P. (1989)
    454. Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. (PubMed id 3487090)1 Clark E.A. and Ledbetter J.A. (1986)
    455. CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis, and cytokine secretion. (PubMed id 11950960)9 Gallagher N.J....Young L.S. (2002)
    456. CD40 expression by human fibroblasts. (PubMed id 7554483)9 Fries K.M....Phipps R.P. (1995)
    457. Regulation of tumor necrosis factor-alpha expression by CD40 ligation in BV-2 microglial cells. (PubMed id 11796758)9 Jana M....Pahan K. (2002)
    458. CD40 expression by human bronchial epithelial cells. (PubMed id 10219759)9 Gormand F....Pacheco Y. (1999)
    459. CD40 is a prognostic marker in primary cutaneous malignant melanoma. (PubMed id 8952530)9 van den Oord J.J....De Wolf-Peeters C. (1996)
    460. Expression of CD40 and growth-inhibitory activity of CD40 ligand in ovarian cancer cell lines. (PubMed id 17166566)9 Melichar B....Freedman R.S. (2007)
    461. CD40 expression in normal human cornea and regulation of CD40 in cultured human corneal epithelial and stromal cells. (PubMed id 11818376)9 Iwata M....Hwang D.G. (2002)
    462. Expression of CD40 and CD40 ligand in the human conjunctival epithelium. (PubMed id 10634610)9 Bourcier T....Baudouin C. (2000)
    463. Post-transcriptional inhibition of CD40 gene expression in microglia by transforming growth factor-beta. (PubMed id 9710231)9 Nguyen V.T....Benveniste E.N. (1998)
    464. CD40 mediated activation of gingival and periodontal ligament fibroblasts. (PubMed id 9100204)9 Sempowski G.D....Blieden T.M. (1997)
    465. CD40 is expressed on human peritoneal mesothelial cells and upregulates the production of interleukin-15 and RANTES. (PubMed id 11274230)9 Basok A....Douvdevani A. (2001)
    466. Expression of functional CD40 in human hepatocellular carcinoma. (PubMed id 10498643)9 Sugimoto K....Nakano T. (1999)
    467. High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization. (PubMed id 10433725)9 Pullen S.S....Kehry M.R. (1999)
    468. High CD40 membrane expression in AIDS-related lymphoma B cell lines is associated with the CD45RA+, CD45RO+, CD95+ phenotype and high levels of its soluble form in culture supernatants. (PubMed id 9056740)9 De Paoli P....Carbone A. (1997)
    469. Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes. (PubMed id 9366415)9 Hsing Y....Bishop G.A. (1997)
    470. CD40 is functionally expressed on human thymic epithelial cells. (PubMed id 1378865)9 Galy A.H. and Spits H. (1992)
    471. [Effect of different patterns activation forms of CD40 on cloning of CD40 mutant and its proliferation and phenotype in RPMI8226 cell line] (PubMed id 18681310)9 Zheng L....Zhang X.G. (2008)
    472. [Functional significance of CD40 and CD40 ligand linking on human lung cells] (PubMed id 14642089)9 Cui W. and Li L.Y. (2003)
    473. Upregulation of CD40 expression on endothelial cells infected with human cytomegalovirus. (PubMed id 12438605)9 Maisch T....Mach M. (2002)
    474. CD40-CD40 ligand (CD154) engagement is required but not sufficient for modulating MHC class I, ICAM-1 and Fas expression and proliferation of human non-small cell lung tumors. (PubMed id 11304696)9 Yamada M....Bankert R.B. (2001)
    475. A polymorphic CD40 ligand (CD154) molecule mediates CD40-dependent signalling but interferes with the ability of soluble CD40 to functionally block CD154:CD40 interactions. (PubMed id 10651941)9 Barnhart B....Covey L.R. (2000)
    476. Expression of the CD40 antigen on normal endothelial cells and in benign and malignant tumours of vascular origin. (PubMed id 8971558)9 Pammer J....Tschachler E. (1996)
    477. Antibodies to distinct epitopes on the CD40 molecule co-operate in stimulation and can be used for the detection of soluble CD40. (PubMed id 7530692)9 Bjorck P....Paulie S. (1994)
    478. Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40. (PubMed id 1698631)9 Inui S....Kishimoto T. (1990)
    479. Fenofibrate inhibits tumor necrosis factor-alpha-indu ced expression of CD40 and matrix metalloproteinase in human vascular endotheli al cells. (PubMed id 17062332)9 Lin R....Fang Z.Y. (2006)
    480. IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia. (PubMed id 16571771)9 Qin H....Benveniste E.N. (2006)
    481. Prognostic significance of CD40 expression in malignant lymphoma developing in rheumatoid arthritis. (PubMed id 16177927)9 Sasaki T....Aozasa K. (2005)
    482. Lovastatin modulation of microglial activation via suppression of functional CD40 expression. (PubMed id 15378516)9 Townsend K.P....Tan J. (2004)
    483. Coexpression of CD40 and CD40L on B lymphoma and carcinoma cells: an autocrine anti-apoptotic role. (PubMed id 15360007)9 Voorzanger-Rousselot N. and Blay J.Y. (2004)
    484. CD40 expression on human pancreatic duct cells: role in nuclear factor-kappa B activation and production of pro-inflammatory cytokines. (PubMed id 15298343)9 Vosters O....Verhasselt V. (2004)
    485. Differential expression of CD40 and CD95 in ovarian carcinoma. (PubMed id 15053058)9 Ciaravino G....Teng N.N. (2004)
    486. CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells. (PubMed id 11689460)9 Afford S.C....Adams D.H. (2001)
    487. Expression of CD40 and CD40 ligand in Bowen's disease and squamous cell carcinoma. (PubMed id 10980464)9 Amo Y....Katsuoka K. (2000)
    488. CD40 is functionally expressed on human breast carcinomas: variable inducibility by cytokines and enhancement of Fas-mediated apoptosis. (PubMed id 9802617)9 Wingett D.G....Nielson C.P. (1998)
    489. Endothelial expression of CD40 in renal cell carcinoma. (PubMed id 9041191)9 Kluth B....Feucht H.E. (1997)
    490. Bidirectional regulation of human B cell responses by CD40-CD40 ligand interactions. (PubMed id 9144474)9 Miyashita T....Lipsky P.E. (1997)
    491. Role of the CD40 and CD95 (APO-1/Fas) antigens in the apoptosis of human B-cell malignancies. (PubMed id 9163608)9 Wang D....Robertson M.J. (1997)
    492. Expression of the co-stimulatory molecule CD40 on melanoma cells. (PubMed id 8980186)9 Thomas W.D....Hersey P. (1996)
    493. CD40 expressed on thymic epithelial cells provides costimulation for proliferation but not for apoptosis of human thymocytes. (PubMed id 8621909)9 Ruggiero G....Spits H. (1996)
    494. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. (PubMed id 8691131)9 Karmann K....Pober J.S. (1996)
    495. CD40 is functionally expressed on human keratinocytes. (PubMed id 8898941)9 Denfeld R.W....Simon J.C. (1996)
    496. CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma. (PubMed id 8623911)9 Pammer J....Tschachler E. (1996)
    497. CD40 cross-linking inhibits specific antibody production by human B cells. (PubMed id 8580079)9 Callard R.E....Costelloe K.E. (1995)
    498. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation. (PubMed id 7543921)9 Yellin M.J....Chess L. (1995)
    499. Expression of CD40 and CD43 during activation of human B lymphocytes. (PubMed id 1708162)9 Bjorck P....Paulie S. (1991)
    500. Nuclear CD40 interacts with c-Rel and enhances proliferation in aggressive B-cell lymphoma. (PubMed id 17567982)9 Zhou H.J....Ford R.J. (2007)
    501. LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia. (PubMed id 16020513)9 Qin H....Benveniste E.N. (2005)
    502. Trapidil inhibits monocyte CD40 expression by preventing IFN-gamma-induced STAT1 S727 phosphorylation. (PubMed id 15182726)9 Zhou L....Stordeur P. (2004)
    503. In situ Expression of CD40 and CD40 ligand in psoriasis. (PubMed id 15237263)9 Ohta Y. and Hamada Y. (2004)
    504. Mouse endothelial CD40 expression does not play a role during the development of transplant arteriosclerosis. (PubMed id 12791519)9 Ensminger S.M....Wood K.J. (2003)
    505. Monocyte CD40 expression in severe sepsis. (PubMed id 12558139)9 Sugimoto K....Pradier O. (2003)
    506. Heterogeneous expression and regulation of CD40 in human hepatocellular carcinoma. (PubMed id 12560754)9 Holub M....Reinisch W. (2003)
    507. Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages. (PubMed id 12193701)9 Wesemann D.R....Benveniste E.N. (2002)
    508. CD40 is not detected on human prostate cancer cells by immunohistologic techniques. (PubMed id 11248650)9 Moghaddami M....Brown M.P. (2001)
    509. Expression of CD40 and CD40 ligand among cell populat ions within rheumatoid synovial compartment. (PubMed id 11905840)9 Liu M.F....Lei H.Y. (2001)
    510. IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia. (PubMed id 11086058)9 Nguyen V.T. and Benveniste E.N. (2000)
    511. Increased CD40 expression on muscle cells of polymyositis and dermatomyositis: role of CD40-CD40 ligand interaction in IL-6, IL-8, IL-15, and monocyte chemoattractant protein-1 production. (PubMed id 10843719)9 Sugiura T....Kamatani N. (2000)
    512. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection. (PubMed id 9892626)9 Afford S.C....Adams D.H. (1999)
    513. Stimulation of CD40 on immunogenic human malignant melanomas augments their cytotoxic T lymphocyte-mediated lysis and induces apoptosis. (PubMed id 10096561)9 von Leoprechting A....Simon J.C. (1999)
    514. Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. (PubMed id 9717810)9 Lollini P.L....Nanni P. (1998)
    515. CD40 expression in epidermal tumors. (PubMed id 9066581)9 Viac J....Claudy A. (1997)
    516. CD40-mediated signals inhibit the binding of TNF receptor-associated factor 2 to the CD40 cytoplasmic domain. (PubMed id 9379019)9 Chaudhuri A....Cherayil B.J. (1997)
    517. Proliferation of precursor B-lineage acute lymphoblastic leukaemia by activating the CD40 antigen. (PubMed id 8904887)9 Planken E.V....Kluin-Nelemans J.C. (1996)
    518. Human dendritic cells activate T lymphocytes via a CD40: CD40 ligand-dependent pathway. (PubMed id 8647193)9 McLellan A.D....Hart D.N. (1996)
    519. Human epidermal keratinocytes are induced to secrete interleukin-6 and co-stimulate T lymphocyte proliferation by a CD40-dependent mechanism. (PubMed id 8647219)9 Gaspari A.A....Phipps R.P. (1996)
    520. Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ. (PubMed id 8921937)9 Feuillard J....Raphael M. (1996)
    521. CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. (PubMed id 7688031)9 Alderson M.R....Spriggs M.K. (1993)
    522. Inhibition by glucocorticoid and staurosporine of IL-4-dependent CD23 production in B lymphocytes is reversed on engaging CD40. (PubMed id 7683590)9 Katira A....Gordon J. (1993)
    523. Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression. (PubMed id 18817573)9 Rezai-Zadeh K....Shytle R.D. (2008)
    524. Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells. (PubMed id 18187173)9 Wu W....Peden D.B. (2008)
    525. IL-10 inhibits lipopolysaccharide-induced CD40 gene expression through induction of suppressor of cytokine signaling-3. (PubMed id 17114447)9 Qin H....Benveniste E.N. (2006)
    526. The expression of CD40 on monocytes of children with primary humoral immunodeficiencies. (PubMed id 16641210)9 Kowalczyk D....Zembala M. (2006)
    527. Nifedipine inhibits tumor necrosis factor-alpha-induced upregulation of monocyte chemoattractant protein-1 mRNA levels by suppressing CD40 expression in endothelial cells. (PubMed id 15921025)9 Yamagishi S. and Takeuchi M. (2005)
    528. TRAF interactions with raft-like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1. (PubMed id 15386359)9 Ardila-Osorio H....Busson P. (2005)
    529. Unique regulation profile of prostaglandin e1 on adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells. (PubMed id 14561849)9 Takahashi H.K....Nishibori M. (2003)
    530. Cytokine balance in kidney tissue from lupus nephritis patients. (PubMed id 12730502)9 Uhm W.S....Yoo D.H. (2003)
    531. Functional CD40 expression induced following bacterial infection of mouse and human osteoblasts. (PubMed id 12595434)9 Schrum L.W....Bost K.L. (2003)
    532. [Inhibition of human glioma cell growth by a soluble recombinant human CD40 ligand] (PubMed id 12508655)9 Gao Y.L....Gu X.S. (2002)
    533. Differential effects of cytokines and immunosuppressive drugs on CD40, B7-1, and B7-2 expression on purified epidermal Langerhans cells1. (PubMed id 10594746)9 Salgado C.G....Tamaki K. (1999)
    534. Inhibition of the CD40 pathway of monocyte activation by triazolopyrimidine. (PubMed id 10600333)9 Zhou L....Pradier O. (1999)
    535. CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs. (PubMed id 10318845)9 Pullen S.S....Kehry M.R. (1999)
    536. Ligation of CD40 induced tumor necrosis factor-alpha in rheumatoid arthritis: a novel mechanism of activation of synoviocytes. (PubMed id 10332965)9 Harigai M....Kashiwazaki S. (1999)
    537. Interferon-gamma-induced ICAM-1 and CD40 expression, complete lack of HLA-DR and CD80 (B7.1), and inconsistent HLA-ABC expression in basal cell carcinoma: a possible role for interleukin-10? (PubMed id 10398091)9 Kooy A.J....Tank B. (1999)
    538. Stimulation of CD40 in human bladder carcinoma cells inhibits anti-Fas/APO-1 (CD95)-induced apoptosis. (PubMed id 9714053)9 Jakobson E....Paulie S. (1998)
    539. CD40 induces resistance to TNF-mediated apoptosis in a fibroblast cell line. (PubMed id 9842902)9 Hess S....Engelmann H. (1998)
    540. IL-4 and CD40 ligation affect differently the differentiation, maturation, and function of human CD34+ cell-derived CD1a+CD14- and CD1a-CD14+ dendritic cell precursors in vitro. (PubMed id 9715264)9 Canque B....Gluckman J.C. (1998)
    541. CD40 ligation of human keratinocytes inhibits their proliferation and induces their differentiation. (PubMed id 8977185)9 Peguet-Navarro J....Schmitt D. (1997)
    542. The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium. (PubMed id 8973616)9 Rissoan M.C....Banchereau J. (1996)
    543. Endothelial cells augment the expression of CD40 ligand on newly activated human CD4+ T cells through a CD2/LFA-3 signaling pathway. (PubMed id 8605928)9 Karmann K....Pober J.S. (1996)
    544. CD40 expression in Hodgkin's disease. (PubMed id 7507299)9 O'Grady J.T....Krajewski A.S. (1994)
    545. The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation. (PubMed id 1740105)9 Ten R.M....Israel A. (1992)
    546. Tumor Necrosis Factor alpha (TNFalpha) regulates CD40 expression through SMAR1 phosphorylation. (PubMed id 20006573)9 Singh K....Chattopadhyay S. (2010)
    547. The immunogenicity of L1210 lymphoma clones correlate s with their ability to function as antigen-presenting cells. (PubMed id 19740325)9 Cycon K.A....Murphy S.P. (2009)
    548. A nuclear factor-kappaB inhibitor BAY11-7082 inhibits interactions between human endothelial cells, T cells, and monocytes. (PubMed id 18929846)9 Zhu B....Xu H. (2008)
    549. Inhibitory effects of Triptolide on interferon-gamma-induced human leucocyte antigen-DR, intercellular adhesion molecule-1, CD40 expression on retro-ocular fibroblasts derived from patients with Graves' ophthalmopathy. (PubMed id 16671908)9 Yan S.X. and Wang Y. (2006)
    550. Novel role of CD40 in Fas-dependent apoptosis of cultured salivary epithelial cells from patients with SjAPgren's syndrome. (PubMed id 15692983)9 Ping L....Sugai S. (2005)
    551. Relation between upregulation of CD40 system and complex stenosis morphology in patients with acute coronary syndrome. (PubMed id 14769218)9 Yan J.C....Zhan L.Z. (2004)
    552. LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. (PubMed id 12637341)9 Li D....Mehta J.L. (2003)
    553. Expression of CD154 on renal cell carcinomas and effect on cell proliferation, motility and platelet-activating factor synthesis. (PubMed id 12209602)9 Bussolati B....Camussi G. (2002)
    554. Synergy between CD40 ligation and IL-4 on fibroblast proliferation involves IL-4 receptor signaling. (PubMed id 11801648)9 Atamas S.P....White B. (2002)
    555. Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases. (PubMed id 12476345)9 O'Keefe G.M....Benveniste E.N. (2002)
    556. Route of monocyte differentiation determines their cytokine production profile: CD40 ligation induces interleukin 10 expression. (PubMed id 11023664)9 Foey A.D....Brennan F.M. (2000)
    557. Tumor necrosis factor alpha and CD40 ligand antagonize the inhibitory effects of interleukin 10 on T-cell stimulatory capacity of dendritic cells. (PubMed id 10969796)9 Brossart P....Brugger W. (2000)
    558. Control of apoptosis in Epstein Barr virus-positive nasopharyngeal carcinoma cells: opposite effects of CD95 and CD40 stimulation. (PubMed id 10029086)9 Sbih-Lammali F....Busson P. (1999)
    559. In situ expression of B7 and CD40 costimulatory molecules by normal human lung macrophages and epithelioid cells in tuberculoid granulomas. (PubMed id 10337027)9 Soler P....Tazi A. (1999)
    560. Surface membrane-expressed CD40 is present on tumor cells from squamous cell cancer of the head and neck in vitro and in vivo and regulates cell growth in tumor cell lines. (PubMed id 10473114)9 Posner M.R....Norris C.M. (1999)
    561. The modulation of B7.2 and B7.1 on B cells by immunos uppressive agents. (PubMed id 10540152)9 Jirapongsananuruk O. and Leung D.Y. (1999)
    562. Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation. (PubMed id 10428814)9 Leo E....Reed J.C. (1999)
    563. Possible role of interleukin-10 (IL-10) and CD40 ligand expression in the pathogenesis of hypergammaglobulinemia in human immunodeficiency virus infection: modulation of IL-10 and Ig production after intravenous Ig infusion. (PubMed id 9808566)9 Muller F....Froland S.S. (1998)
    564. Regulation of CD80/B7-1 and CD86/B7-2 molecule expression in human primary acute myeloid leukemia and their role in allogenic immune recognition. (PubMed id 9485189)9 Costello R.T....Olive D. (1998)
    565. Localization in situ of costimulatory molecules and cytokines in B-cell non-Hodgkin's lymphoma. (PubMed id 9767448)9 Vyth-Dreese F.A....De Jong D. (1998)
    566. CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells. (PubMed id 9541585)9 Worm M.M....Geha R.S. (1998)
    567. Activation of B-lymphocytes during pollen season. Effect of immunotherapy. (PubMed id 9720812)9 HAYkansson L....Venge P. (1998)
    568. Expression of costimulatory molecules B7-1, B7-2, and CD40 in the heart of patients with acute myocarditis and dilated cardiomyopathy. (PubMed id 9495297)9 Seko Y....Yazaki Y. (1998)
    569. Interleukin-1 beta and granulocyte-macrophage colony-stimulating factor mediate Langerhans cell maturation differently. (PubMed id 8648174)9 Ozawa H....Aiba S. (1996)
    570. CD40 function in nonhematopoietic cells. Nuclear factor kappa B mobilization and induction of IL-6 production. (PubMed id 7594457)9 Hess S....Engelmann H. (1995)
    571. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. (PubMed id 7595197)9 Garrone P....Banchereau J. (1995)
    572. Identification of residues on CD40 and its ligand which are critical for the receptor-ligand interaction. (PubMed id 7531493)9 Bajorath J....Aruffo A. (1995)
    573. Beta-adrenergic-induced CD40 overexpression on gingiv al fibroblasts: role of PGE2. (PubMed id 19947915)9 FurlA!n C....Borda E. (2010)
    574. CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle. (PubMed id 19220210)9 Krimmer D.I....Burgess J.K. (2009)
    575. Inhibition of apoptosis, activation of NKT cell and upregulation of CD40 and CD40L mediated by M. leprae antigen(s) combined with Murabutide and Trat peptide in leprosy patients. (PubMed id 18008143)9 Chattree V....Rao D.N. (2008)
    576. Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. (PubMed id 18303186)9 Miyazawa M....Nishiyama N. (2008)
    577. Effects of different LDL particles on inflammatory molecules in human mesangial cells. (PubMed id 18751966)9 Santini E....Solini A. (2008)
    578. Inflammatory and vasoactive factors in the aspirate from the culprit coronary artery of patients with acute myocardial infarction. (PubMed id 16309761)9 Ko Y.G....Cho S.Y. (2006)
    579. Expression of CD40 and CD40L on peripheral blood mono nuclear cells in patients with condyloma acuminatum. (PubMed id 16961300)9 Liu D....Yang D. (2006)
    580. Sensitization of multiple myeloma and B lymphoma lines to dexamethasone and gamma-radiation-induced apoptosis by CD40 activation. (PubMed id 15711928)9 Zhou Z.H....Zhang X.G. (2005)
    581. Upregulation of CD40, CD80, CD83 or CD86 on alveolar macrophages after lung transplantation. (PubMed id 16102442)9 Nicod L.P....Pache J.C. (2005)
    582. Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study. (PubMed id 16205698)9 Lessard L....Saad F. (2005)
    583. Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. (PubMed id 15618295)9 Takahashi H.K....Nishibori M. (2005)
    584. Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes. (PubMed id 14981114)9 Xie P....Bishop G.A. (2004)
    585. beta2-adrenergic receptor stimulation-induced immunosuppressive effects possibly through down-regulation of co-stimulatory molecules, ICAM-1, CD40 and CD14 on monocytes. (PubMed id 15458278)9 Kuroki K....Tanemoto K. (2004)
    586. Role of tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) in distinct and overlapping CD40 and TNF receptor 2/CD120b-mediated B lymphocyte activation. (PubMed id 15485859)9 Munroe M.E. and Bishop G.A. (2004)
    587. [Expression of NF-kappa B in human bladder cancer and its clinical significance] (PubMed id 12452071)9 Xie D.H....Cai Y. (2002)
    588. Aberrant nuclear factor-kappaB activity and its participation in the growth of human malignant astrocytoma. (PubMed id 12005399)9 Nagai S....Kumanishi T. (2002)
    589. CD40-expressing carcinoma cells induce down-regulation of CD40 ligand (CD154) and impair T-cell functions. (PubMed id 11929824)9 Batrla R....GA1ckel B. (2002)
    590. [Costimulatory molecule expression on allergen-stimul ated PBMC in cedar pollinosis subjects] (PubMed id 11305050)9 Morikawa H. and Baba K. (2001)
    591. Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody. (PubMed id 11525169)9 Karpusas M....Hsu Y.M. (2001)
    592. Expression of CD40 and apoptosis related molecules in autoimmune thyroid diseases. (PubMed id 11675676)9 Kie J.H....Yang W.I. (2001)
    593. RelA, p50 and inhibitor of kappa B alpha are elevated in human metastatic melanoma cells and respond aberrantly to ultraviolet light B. (PubMed id 11775058)9 McNulty S.E....Meyskens F.L. (2001)
    594. Systemic upregulation of CD40 and CD40 ligand mRNA expression in multiple sclerosis. (PubMed id 10773848)9 Huang W.X....Hillert J. (2000)
    595. The amino-terminus and membrane-spanning domains of LMP-1 inhibit cell proliferation. (PubMed id 10723131)9 Kaykas A. and Sugden B. (2000)
    596. Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions. (PubMed id 10623803)9 Jalukar S.V....Bishop G.A. (2000)
    597. Tumour-necrosis-factor-receptor-associated factor 6, NF-kappaB-inducing kinase and IkappaB kinases mediate IgE isotype switching in response to CD40. (PubMed id 10970786)9 Brady K....Moynagh P.N. (2000)
    598. Analysis of TNF-receptor and ligand superfamily molecules in patients with lymphoproliferative disease of granular lymphocytes. (PubMed id 10887130)9 Zambello R....Semenzato G. (2000)
    599. Characterization of RNA binding proteins associated with CD40 ligand (CD154) mRNA turnover in human T lymphocytes. (PubMed id 10510356)9 Rigby W.F....Hamilton B.J. (1999)
    600. CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection. (PubMed id 10201021)9 Gaweco A.S....Van Thiel D.H. (1999)
    601. Liver and bile duct pathology following Cryptosporidium parvum infection of immunodeficient mice. (PubMed id 10385635)9 Stephens J....Hayward A. (1999)
    602. Impairment of T-cell activation in head and neck cancer in situ and in vitro: strategies for an immune restoration. (PubMed id 9932594)9 Lang S....Wollenberg B. (1999)
    603. Expression of CD40 and its ligand, CD40L, in intestinal lesions of Crohn's disease. (PubMed id 10566730)9 Battaglia E....Camussi G. (1999)
    604. Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation. (PubMed id 9990039)9 Lee H.H....Cheng G. (1999)
    605. Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50. (PubMed id 9742085)9 Baer M....Johnson P.F. (1998)
    606. Expression and function of CD40 in rheumatoid arthritis synovium. (PubMed id 9632061)9 Sekine C....Okumura K. (1998)
    607. Assembly and regulation of the CD40 receptor complex in human B cells. (PubMed id 9221764)9 KuhnAc M.R....Calderhead D.M. (1997)
    608. Upregulation of CD40 and CD40 ligand expression in IgE-associated cutaneous diseases. (PubMed id 9394977)9 Hermes B....Henz B.M. (1997)
    609. Memory, but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and costimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3. (PubMed id 9278293)9 Kindler V. and Zubler R.H. (1997)
    610. Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides. (PubMed id 9008608)9 Yellin M.J....Chess L. (1997)
    611. Antibody to gp39, the ligand for CD40 significantly inhibits the humoral response from Graves' thyroid tissues xenografted into severe combined immunodeficient (SCID) mice. (PubMed id 8875745)9 Resetkova E....VolpAc R. (1996)
    612. Functional expression of CD40 antigen on human epidermal Langerhans cells. (PubMed id 7594581)9 PAcguet-Navarro J....Schmitt D. (1995)
    613. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. (PubMed id 7533177)9 Burdin N....Rousset F. (1995)
    614. [Reconstitution of immunoglobulin production in patients with variable immunodeficiency syndrome (CVI) by the CD40 system and IL-10] (PubMed id 7523284)9 Zielen S....Meuer S.C. (1994)
    615. Structural characteristics of CD40 ligand that determ ine biological function. (PubMed id 7532457)9 Fanslow W.C....Armitage R.J. (1994)
    616. Regulation of ICAM-1 (CD54) expression in human breast cancer cell lines by interleukin 6 and fibroblast-derived factors. (PubMed id 7516927)9 Hutchins D. and Steel C.M. (1994)
    617. CD40-activated surface IgD-positive lymphocytes constitute the long term IL-4-dependent proliferating B cell pool. (PubMed id 7504711)9 Galibert L....Rousset F. (1994)
    618. Inhibition of human B-cell lymphoma growth by CD40 stimulation. (PubMed id 7514045)9 Funakoshi S....Murphy W.J. (1994)
    619. Two FKBP-related proteins are associated with progesterone receptor complexes. (PubMed id 7688746)9 Smith D.F....Rimerman R.A. (1993)
    620. Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. (PubMed id 1634604)9 Kaufman P.A....Greene W.C. (1992)
    621. Beta2-adrenoceptor stimulation inhibits advanced glyc ation end products-induced adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells. (PubMed id 19857486)9 Takahashi H.K....Nishibori M. (2010)
    622. Circulating levels and hepatic expression of molecula r mediators of atherosclerosis in nonalcoholic fatty liver disease. (PubMed id 19896127)9 Sookoian S....Pirola C.J. (2010)
    623. Effects of labetalol on hemodynamic parameters and so luble biomarkers of inflammation in acute coronary syndrome in patients with ac tive cocaine use. (PubMed id 20133495)9 Hoskins M.H....Khan B.V. (2010)
    624. Low expression of T-cell co-stimulatory molecules in bone marrow-derived dendritic cells in a mouse model of chronic respiratory inf ection with Pseudomonas aeruginosa. (PubMed id 20046053)9 Mukae H....Kohno S. (2010)
    625. Signalling pathways involved in the activation of den dritic cells by layered double hydroxide nanoparticles. (PubMed id 19853910)9 Li A....Wang S. (2010)
    626. Ketamine inhibits maturation of bone marrow-derived d endritic cells and priming of the Th1-type immune response. (PubMed id 19690248)9 Ohta N....Fujino Y. (2009)
    627. Tumor necrosis factor-alpha in ocular mucous membrane pemphigoid and its effect on conjunctival fibroblasts. (PubMed id 19494201)9 Saw V.P....Calder V.L. (2009)
    628. Etanercept impairs maturation of human monocyte-derived dendritic cells by inhibiting the autocrine TNFalpha-mediated signaling. (PubMed id 19301111)9 Slobodin G....Toubi E. (2009)
    629. Expression of CD40 and CD40L in gastric cancer tissue and its clinical significance. (PubMed id 19865524)9 Li R....Zhang X.G. (2009)
    630. Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1. (PubMed id 19117935)9 Hwang C.J....Douglas R.S. (2009)
    631. Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. (PubMed id 19349372)9 Liu M....Pestell R.G. (2009)
    632. Early events associated with infection of Epstein-Bar r virus infection of primary B-cells. (PubMed id 19784370)9 Halder S....Robertson E.S. (2009)
    633. Circulating interleukin-6 and high-sensitivity C-reactive protein decrease after periodontal therapy in otherwise healthy subjects. (PubMed id 19335079)9 Marcaccini A.M....Gerlach R.F. (2009)
    634. The multi-functionality of CD40L and its receptor CD4 0 in atherosclerosis. (PubMed id 19652870)9 Lievens D....Lutgens E. (2009)
    635. Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells. (PubMed id 19723087)9 Reuter S....Diederich M. (2009)
    636. TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation. (PubMed id 19164127)9 LarangAc A....Kerdine-RAPmer S. (2009)
    637. TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation. (PubMed id 18228247)9 Vanden Bush T.J. and Bishop G.A. (2008)
    638. Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO4. (PubMed id 18303184)9 Miyazawa M....Nishiyama N. (2008)
    639. Relationship between plasma levels of soluble CD40L and insulin sensitivity and insulin secretion status in non-diabetic dyslipidemic patients. (PubMed id 17716773)9 Filozof C....Fernandez-Cruz A. (2008)
    640. The influence of alpha1-antagonist on the expression pattern of TNF receptor family in primary culture of prostate epithelial cells from BPH patients. (PubMed id 17533395)9 Drewa T....Styczynski J. (2008)
    641. Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF-kappaB pathway. (PubMed id 18500358)9 Johansson A.S....Palmblad J. (2008)
    642. Predictive value of serum-soluble CD154 in fulminant hepatic failure. (PubMed id 18652769)9 Zheng Y.B....Chong Y.T. (2008)
    643. CD40 expression on antigen presenting cells and correlation with disease severity in atopic dermatitis. (PubMed id 18693155)9 Oflazoglu E....Gerber H.P. (2008)
    644. Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction. (PubMed id 18652845)9 Fedoric B. and Krishnan R. (2008)
    645. CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice. (PubMed id 18606155)9 Laporte V....Mullan M. (2008)
    646. Expression of cytokeratins, adhesion and activation molecules in oral ulcers of Behcet's disease. (PubMed id 17983454)9 Kose O....Fortune F. (2008)
    647. Protective anti-mycobacterial T cell responses through exquisite in vivo activation of vaccine-targeted dendritic cells. (PubMed id 18412160)9 Kamath A.T....Siegrist C.A. (2008)
    648. Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF-kappaB pathways and promotes osteoclastogenesis in human oral cancer cells. (PubMed id 18310089)9 Tang C.H....Hung C.H. (2008)
    649. Bradykinin-induced IL-6 expression through bradykinin B2 receptor, phospholipase C, protein kinase Cdelta and NF-kappaB pathway in human synovial fibroblasts. (PubMed id 18621420)9 Lee C.H....Tang C.H. (2008)
    650. TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells. (PubMed id 17332487)9 Zirlik A....Schonbeck U. (2007)
    651. Expression of functional Toll-like receptors by salivary gland epithelial cells: increased mRNA expression in cells derived from patients with primary Sjogren's syndrome. (PubMed id 17302899)9 Spachidou M.P....Manoussakis M.N. (2007)
    652. High plasma levels of CD40 are associated with low coenzyme Q and vitamin E content of low-density lipoprotein in healthy men. (PubMed id 17365991)9 Luomala M....LehtimAoki T. (2007)
    653. NF-kappaB plays a major role in the maturation of human dendritic cells induced by NiSO(4) but not by DNCB. (PubMed id 17636246)9 Ade N....Pallardy M. (2007)
    654. Incorporation of glycosylphosphatidylinositol-anchored granulocyte- macrophage colony-stimulating factor or CD40 ligand enhances immunogenicity of chimeric simian immunodeficiency virus-like particles. (PubMed id 17108046)9 Skountzou I....Kang S.M. (2007)
    655. Analysis of variation in NF-kappaB genes and expression levels of NF-kappaB-regulated molecules. (PubMed id 18466468)9 Liu-Mares W....Goode E.L. (2007)
    656. NOS2 regulation of NF-kappaB by S-nitrosylation of p65. (PubMed id 17720813)9 Kelleher Z.T....Marshall H.E. (2007)
    657. Autoimmune thrombocytopenia: flow cytometric determination of platelet-associated CD154/CD40L and CD40 on peripheral blood T and B lymphocytes. (PubMed id 17654056)9 Meabed M.H....El-Hadidy K.S. (2007)
    658. Interaction of calreticulin with CD40 ligand, TRAIL and Fas ligand. (PubMed id 17953526)9 Duus K....Houen G. (2007)
    659. Expression of CCR2A, an isoform of MCP-1 receptor, is increased by MCP-1, CD40 ligand and TGF-beta in fibroblast like synoviocytes of patients with RA. (PubMed id 17934338)9 Cho M.L....Kim H.Y. (2007)
    660. Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity. (PubMed id 17073943)9 Hao S....Xiang J. (2007)
    661. Markers of apoptosis and proliferation related gene products as predictors of treatment outcome in childhood acute lymphoblastic leukemia. (PubMed id 17558696)9 Hafez M....Farahat N. (2007)
    662. Expression of CD40 and CD40L on tumor cells: the role of their interaction and new approach to immunotherapy. (PubMed id 17431381)9 Bereznaya N.M. and Chekhun V.F. (2007)
    663. Plasmid DNA and IL-4 modulate expression of mHC class I and costimulatory molecules in B lymphocytes. (PubMed id 17417943)9 Frazzi R. and Zanetti M. (2007)
    664. Soluble CD40 ligand:interleukin-10 ratio predicts in-hospital adverse events in patients with ST-segment elevation myocardial infarction. (PubMed id 17521712)9 Dominguez-Rodriguez A....Kaski J.C. (2007)
    665. Protein-protein interactions in TRAF3. (PubMed id 17633021)9 Ely K.R....Wu S. (2007)
    666. Cloning, sequence analysis and expression of ovine CD154 (CD40 ligand). (PubMed id 16777229)9 Oledzka G....Stankiewicz M. (2007)
    667. [Effects of two different antigen-loading methods on the activity of dendritic cell vaccine for colorectal carcinoma cell inhibition in vitro] (PubMed id 17545041)9 Huang H....Hermonat P.L. (2007)
    668. Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand. (PubMed id 17237425)9 Chen K....Wang J.M. (2007)
    669. Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma. (PubMed id 17268792)9 Diaconu N.C....Harvima I.T. (2007)
    670. Therapeutic vaccination against murine lymphoma by intratumoral injection of recombinant fowlpox virus encoding CD40 ligand. (PubMed id 17638917)9 Liu A....Levy R. (2007)
    671. Progesterone receptor expression by human leukocyte cell lines: molecular mechanisms of cytokine suppression. (PubMed id 17447631)9 Srivastava M.D. and Anderson D.J. (2007)
    672. Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with CD40-CD40L-mediated endogenous production of interleukin-12. (PubMed id 17961770)9 Bose A. and Baral R. (2007)
    673. Lovastatin reduces apoptosis and downregulates the CD40 expression induced by TNF-alpha in cerebral vascular endothelial cells. (PubMed id 16472124)9 Lin R....Ding C. (2006)
    674. Transfection of CD40 in a human oral squamous cell carcinoma keratinocyte line upregulates immune potency and costimulatory molecules. (PubMed id 16433790)9 Villarroel Dorrego M....Barrett A.W. (2006)
    675. Detection of epsilon class switching and IgE synthesis in human B cells. (PubMed id 16110166)9 PA"ne J....Gauchat J.F. (2006)
    676. In situ glomerular expression of activated NF-kappaB in human lupus nephritis and other non-proliferative proteinuric glomerulopathy. (PubMed id 16205945)9 Zheng L....Hsu S.I. (2006)
    677. Acute lymphoblastic leukaemia cells express CCR7 but not higher amounts of IL-10 after CD40 ligation. (PubMed id 17101562)9 Luczynski W....Wieczorek M. (2006)
    678. Is there more than C-reactive protein and fibrinogen? The prognostic value of soluble CD40 ligand, interleukin-6 and oxidized low-density lipoprotein with respect to coronary and cerebral vascular disease. (PubMed id 16360159)9 Lobbes M.B....Nelemans P.J. (2006)
    679. Low expression of costimulatory molecules and mRNA for cytokines are important mechanisms of immunosuppression in acute lymphoblastic leukemia in children? (PubMed id 16830056)9 LuczyA8ski W....Jaworowski R. (2006)
    680. The ICOS-ligand B7-H2, expressed on human type II alv eolar epithelial cells, plays a role in the pulmonary host defense system. (PubMed id 16552709)9 Qian X....Hayashi T. (2006)
    681. The immunosuppressive effects of ciprofloxacin during human mixed lymphocyte reaction. (PubMed id 16458073)9 Katsuno G....Tanaka N. (2006)
    682. Pioglitazone decreased CD40/CD40L expression on human umbilical vein endothelial cells induced by oxidized low-density lipoprotein. (PubMed id 16545355)9 Jiang D.Q....Zhang S.B. (2006)
    683. Induction of murine liver damage by overexpression of CD40 ligand provides an experimental model to study fulminant hepatic failure. (PubMed id 16871541)9 Schmitz V....Leifeld L. (2006)
    684. RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. (PubMed id 15678102)9 Gohda J....Inoue J. (2005)
    685. Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis. (PubMed id 15730398)9 McCully M.L....Madrenas J. (2005)
    686. Interferon-gamma production by human cord blood monocyte-derived dendritic cells. (PubMed id 15812666)9 Yamaguchi N....Hara H. (2005)
    687. Therapeutic peptidomimetic strategies for autoimmune diseases: costimulation blockade. (PubMed id 15885118)9 Allen S.D....Kaumaya P.T. (2005)
    688. Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes. (PubMed id 15840408)9 Takahashi H.K....Nishibori M. (2005)
    689. Coexpression of CD40 and CD40 ligand in Epstein-Barr virus-infected T and NK cells and their role in cell survival. (PubMed id 16170750)9 Imadome K....Fujiwara S. (2005)
    690. Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features. (PubMed id 15661021)9 Lougaris V....Plebani A. (2005)
    691. Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential. (PubMed id 15741223)9 Watanabe N....Soumelis V. (2005)
    692. CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis. (PubMed id 15591506)9 Gao D....Hecker M. (2005)
    693. Inhibition of immunoglobulin E synthesis through Fc gammaRII (CD32) by a mechanism independent of B-cell receptor co-cross-linking. (PubMed id 15946258)9 Horejs-Hoeck J....Woisetschlager M. (2005)
    694. Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system. (PubMed id 15833357)9 Wischhusen J....Weller M. (2005)
    695. Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells. (PubMed id 15936988)9 Takahashi H.K....Nishibori M. (2005)
    696. NF-kappaB activation during Rickettsia rickettsii infection of endothelial cells involves the activation of catalytic IkappaB kinases IKKalpha and IKKbeta and phosphorylation-proteolysis of the inhibitor protein IkappaBalpha. (PubMed id 15618150)9 Clifton D.R....Sahni S.K. (2005)
    697. Regulation of tyrosine phosphorylation during the CD40-mediated rescue of Ramos-BL B cells from BCR-triggered apoptosis. (PubMed id 16211267)9 Hristov K.K....Mitev V.I. (2005)
    698. Inflammatory mediators are associated with 1-year mortality in critical limb ischemia. (PubMed id 16012455)9 Barani J....GottsAoter A. (2005)
    699. Increased levels of CD40-CD40 ligand system in patients with essential hypertension. (PubMed id 15820495)9 Yan J.C....Zhan L.Z. (2005)
    700. alpha1-Adrenergic receptor antagonists induce production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. (PubMed id 15614043)9 Takahashi H.K....Nishibori M. (2005)
    701. Anti-inflammatory effects of clopidogrel intake in renal transplant patients: effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkers. (PubMed id 16321613)9 Graff J....Gossmann J. (2005)
    702. Impaired accessory cell function in a human dendritic cell line after human immunodeficiency virus infection. (PubMed id 15753259)9 Beuria P....Sperber K. (2005)
    703. The TRAF6, but not the TRAF2/3, binding domain of CD40 is required for cytokine production in human lung fibroblasts. (PubMed id 16143987)9 Purkerson J.M....Phipps R.P. (2005)
    704. [Molecular mechanisms of salivary gland destruction in patients with Sjogren's syndrome. ] (PubMed id 15744117)9 Ogawa N....Kawanami T. (2005)
    705. Retinoic acid inhibits the proliferative response induced by CD40 activation and interleukin-4 in mantle cell lymphoma. (PubMed id 15695403)9 Guidoboni M....Dolcetti R. (2005)
    706. CD40 ligand: a novel target in the fight against cardiovascular disease. (PubMed id 15280513)9 Vishnevetsky D....Gandhi P.J. (2004)
    707. Synergistic B cell activation by CD40 and the B cell antigen receptor: role of B lymphocyte antigen receptor-mediated kinase activation and tumor necrosis factor receptor-associated factor regulation. (PubMed id 14604983)9 Haxhinasto S.A. and Bishop G.A. (2004)
    708. [Functional modulating effect of CD40 ligand on CD40- transfected human lung carcinomas] (PubMed id 15196434)9 Cui W. and Li L.Y. (2004)
    709. Enhanced P-selectin expression and increased soluble CD40 Ligand in patients with Type 1 diabetes mellitus and microangiopathy: evidence for platelet hyperactivity and chronic inflammation. (PubMed id 14963650)9 Yngen M....Wallen N.H. (2004)
    710. Effect of atorvastatin on the expression of CD40 ligand and P-selectin on platelets in patients with hypercholesterolemia. (PubMed id 15276107)9 Hwang Y.S....Chen Y.F. (2004)
    711. The hyper IgM syndrome--an evolving story. (PubMed id 15319456)9 Etzioni A. and Ochs H.D. (2004)
    712. Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation. (PubMed id 14691250)9 Luftig M....Kieff E. (2004)
    713. In situ demonstration of CD40- and CD154-positive cells in psoriatic lesions and keratinocyte production of chemokines by CD40 ligation in vitro. (PubMed id 15221944)9 Pasch M.C....Asghar S.S. (2004)
    714. The role of CD40 ligand in systemic lupus erythematosus. (PubMed id 15230296)9 Yazdany J. and Davis J. (2004)
    715. Complex mechanisms for inhibition of immunoglobulin gene expression in a germinal center B cell line. (PubMed id 15140576)9 Bernstein R.M....Max E.E. (2004)
    716. HLA-DR, ICAM-1, CD40, CD40L, and CD86 are incorporated to a similar degree into clinical human immunodeficiency virus type 1 variants expanded in natural reservoirs such as peripheral blood mononuclear cells and human lymphoid tissue cultured ex vivo. (PubMed id 15183148)9 Martin G. and Tremblay M.J. (2004)
    717. Interferon-beta up-regulates the expression of co-stimulatory molecules CD80, CD86 and CD40 on monocytes: significance for treatment of multiple sclerosis. (PubMed id 15544628)9 Marckmann S....Windhagen A. (2004)
    718. Expression and localization of nuclear factor-kappa B subunits in cultured human paranasal sinus mucosal cells. (PubMed id 12868372)9 Osada R....Yajin K. (2003)
    719. Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L. (PubMed id 12771917)9 Airoldi I....Corrias M.V. (2003)
    720. Expression of CD40 has no predictive value in soft tissue sarcomas. (PubMed id 12820428)9 Ottaiano A....Iaffaioli R.V. (2003)
    721. Oxygen conformance of cellular respiration. A perspective of mitochondrial physiology. (PubMed id 14713113)9 Gnaiger E. (2003)
    722. Autologous immunotherapy for human leukemias. (PubMed id 12850495)9 Claxton D. and Kao S.F. (2003)
    723. IFN regulatory factor-1 is required for the up-regulation of the CD40-NF-kappa B activator 1 axis during airway inflammation. (PubMed id 12759449)9 Zhao Z....Li X. (2003)
    724. Survival and proliferation factors of normal and malignant plasma cells. (PubMed id 12953803)9 Klein B....Rossi J.F. (2003)
    725. B cells in the aged: CD27, CD5, and CD40 expression. (PubMed id 12714244)9 Colonna-Romano G....Caruso C. (2003)
    726. Expression of serotherapy target antigens in Waldenstrom's macroglobulinemia: therapeutic applications and considerations. (PubMed id 12720146)9 Treon S.P....Anderson K.C. (2003)
    727. Inhibition of interferon (IFN) gamma-induced Jak-STAT1 activation in microglia by vasoactive intestinal peptide: inhibitory effect on CD40, IFN-induced protein-10, and inducible nitric-oxide synthase expression. (PubMed id 12754213)9 Delgado M. (2003)
    728. Enhanced levels of CD154 (CD40 ligand) on platelets in patients with chronic heart failure. (PubMed id 14607202)9 Stumpf C....Garlichs C.D. (2003)
    729. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. (PubMed id 12874180)9 Verma S....Mickle D.A. (2003)
    730. IL-10 enhances B-cell IgE synthesis by promoting differentiation into plasma cells, a process that is inhibited by CD27/CD70 interaction. (PubMed id 12197885)9 Kobayashi N....Agematsu K. (2002)
    731. Triptolide is a potent suppressant of C3, CD40 and B7h expression in activated human proximal tubular epithelial cells. (PubMed id 12234299)9 Hong Y....Sacks S.H. (2002)
    732. CD40 stimulation leads to effective therapy of CD40(- ) tumors through induction of strong systemic cytotoxic T lymphocyte immunity. (PubMed id 11929985)9 van Mierlo G.J....Toes R.E. (2002)
    733. Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1. (PubMed id 11781233)9 Wagner A.H....Hecker M. (2002)
    734. B7-1 (CD80) and B7-2 (CD 86) expression in human tubular epithelial cells in vivo and in vitro. (PubMed id 12372936)9 Niemann-Masanek U....van der Woude F.J. (2002)
    735. c-Rel is a selective activator of a novel IL-4/CD40 responsive element in the human Ig gamma4 germline promoter. (PubMed id 11922943)9 Agresti A. and Vercelli D. (2002)
    736. Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS. (PubMed id 11929776)9 Zimmer M.I....Barratt-Boyes S.M. (2002)
    737. Aberrant expression of the costimulatory molecule CD40 ligand on monocytes from patients with systemic lupus erythematosus. (PubMed id 11987985)9 Katsiari C.G....Sfikakis P.P. (2002)
    738. CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1. (PubMed id 11886848)9 Mann J....Mann D.A. (2002)
    739. Interferon-alpha induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo. (PubMed id 12145689)9 Paquette R.L....Glaspy J.A. (2002)
    740. In vitro expression of fas and CD40 and induction of apoptosis in human cystic fibrosis airway epithelial cells. (PubMed id 12000003)9 Amsellem C....PachAcco Y. (2002)
    741. B cells activated via CD40 and IL-4 undergo a divisio n burst but require continued stimulation to maintain division, survival and di fferentiation. (PubMed id 11298340)9 Rush J.S. and Hodgkin P.D. (2001)
    742. Coexpression of normal and mutated CD40 ligand with deletion of a putative RNA lariat branchpoint sequence in X-linked hyper-IgM syndrome. (PubMed id 11358428)9 Zhu X....Scholl P.R. (2001)
    743. Differential regulation of myocardial NF kappa B following acute or chronic TNF-alpha exposure. (PubMed id 11444928)9 Haudek S.B....Giroir B.P. (2001)
    744. Maturation of dendritic cells by recombinant human CD40L-trimer leads to a homogeneous cell population with enhanced surface marker expression and increased cytokine production. (PubMed id 11422906)9 WA1rtzen P.A....Claesson M.H. (2001)
    745. CD40 and IFN-gamma dependent T cell activation by human bronchial epithelial cells. (PubMed id 11286011)9 Tanaka H....Sone S. (2001)
    746. Effect of trapidil on effector functions of monocytes related to atherosclerotic plaque. (PubMed id 11689197)9 Kato Y....Mochizuki H. (2001)
    747. Tubular lesions and tubular cell adhesion molecules for the prognosis of lupus nephritis. (PubMed id 11737595)9 Daniel L....Berland Y. (2001)
    748. Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells. A model for immunotherapy. (PubMed id 11495701)9 Dotti G....Brenner M. (2001)
    749. Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation. (PubMed id 11306145)9 Szeberenyi J.B....Laszlo V. (2001)
    750. Modification of fibroblast gamma-interferon responses by extracellular matrix. (PubMed id 11442757)9 Kern A....Mansbridge J. (2001)
    751. Interferon-gamma enhances interleukin 12 production in rheumatoid synovial cells via CD40-CD154 dependent and independent pathways. (PubMed id 11508577)9 Kitagawa M....Sumida T. (2001)
    752. Expression of CD40 ligand, interferon-gamma and Fas ligand genes in endomyocardial biopsies of human cardiac allografts: correlation with acute rejection. (PubMed id 11378668)9 Shulzhenko N....Gerbase-Delima M. (2001)
    753. Bi-directional activation between human airway smooth muscle cells and T lymphocytes: role in induction of altered airway responsiveness. (PubMed id 11123305)9 Hakonarson H....Grunstein M.M. (2001)
    754. Effects of prolactin on HLA-DR and CD40 expressions by human thyrocytes. (PubMed id 11729509)9 Li J....Shan Z. (2001)
    755. Effect of different activation stimuli on the cytokine response of human macrophages to CD40L. (PubMed id 11792121)9 Bolacchi F....Bergamini A. (2001)
    756. Flow cytometric analysis of inflammatory markers in conjunctival epithelial cells of patients with dry eyes. (PubMed id 10798650)9 Brignole F....Baudouin C. (2000)
    757. IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells. (PubMed id 10925267)9 KaliA8ski P....Kapsenberg M.L. (2000)
    758. Production of IL-10 and IL-12 in CD40 and interleukin 4-activated mononuclear cells from patients with Graves' disease. (PubMed id 10843746)9 Itoh M....Nagasaka A. (2000)
    759. Altered expression of costimulatory molecules in myasthenia gravis. (PubMed id 10842273)9 Teleshova N....Link H. (2000)
    760. CD40 expressed on human melanoma cells mediates T cell co-stimulation and tumor cell growth. (PubMed id 10837406)9 Pirozzi G....Manzo C. (2000)
    761. Expression of CD40 in the brain of Alzheimer's disease and other neurological diseases. (PubMed id 11121537)9 Togo T....Kosaka K. (2000)
    762. Analysis of CD154 and CD40 expression in native coronary atherosclerosis and transplant associated coronary artery disease. (PubMed id 10993275)9 Szabolcs M.J....Yellin M.J. (2000)
    763. Contribution of NF-kappaB and p53 in the glutamate-induced apoptosis. (PubMed id 10817929)9 Uberti D....Memo M. (2000)
    764. Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome. (PubMed id 11059686)9 Sacco M.G....Vezzoni P. (2000)
    765. Stress-induced apoptosis is not mediated by endolysosomal ceramide. (PubMed id 10627278)9 Segui B....Levade T. (2000)
    766. Granulocyte-macrophage colony-stimulating factor, interleukin-2, and interleukin-12 synergize with calcium ionophore to enhance dendritic cell function. (PubMed id 10838660)9 Bedrosian I....Czerniecki B.J. (2000)
    767. TRAF-3 interacts with p62 nucleoporin, a component of the nuclear pore central plug that binds classical NLS-containing import complexes. (PubMed id 10781837)9 Gamper C....Lederman S. (2000)
    768. Impaired antigen-presenting cell function contributes to T-cell hyporesponsiveness in stable lung transplant recipients. (PubMed id 10798749)9 Knoop C....Goldman M. (2000)
    769. Interferon gamma priming is not critical for IL-12 production of murine spleen cells. (PubMed id 10623437)9 Hino A....Nariuchi H. (2000)
    770. CD154 variants associated with hyper-IgM syndrome can form oligomers and trigger CD40-mediated signals. (PubMed id 10559240)9 Garber E....Hsu Y.M. (1999)
    771. Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides. (PubMed id 10535333)9 Tan J....Mullan M. (1999)
    772. Incorporation of an isoleucine zipper motif enhances the biological activity of soluble CD40L (CD154). (PubMed id 9867859)9 Morris A.E....Armitage R.J. (1999)
    773. Elevated CD154 (CD40 ligand) synthesis in T-cells from allergic patients after nonspecific stimulation in vitro. (PubMed id 10513352)9 Markert U.R....Zwacka G. (1999)
    774. Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis. (PubMed id 10408982)9 Tan J....Mullan M. (1999)
    775. Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells. (PubMed id 10601993)9 Baccam M. and Bishop G.A. (1999)
    776. Differential expression of costimulatory molecules in chronic inflammatory periodontal disease tissue. (PubMed id 9933436)9 Orima K....Hara K. (1999)
    777. Interleukin-12 production by human alveolar macrophages is controlled by the autocrine production of interleukin-10. (PubMed id 9922218)9 Isler P....Nicod L.P. (1999)
    778. Costimulatory markers in muscle of patients with idiopathic inflammatory myopathies and in cultured muscle cells. (PubMed id 10444360)9 Nagaraju K....Plotz P.H. (1999)
    779. Expression of stromelysin-3 in atherosclerotic lesions: regulation via CD40-CD40 ligand signaling in vitro and in vivo. (PubMed id 10049948)9 Schonbeck U....Libby P. (1999)
    780. A comparison of primary endothelial cells and endothelial cell lines for studies of immune interactions. (PubMed id 10638837)9 Lidington E.A....Rose M.L. (1999)
    781. Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure. (PubMed id 10362796)9 Leifeld L....Spengler U. (1999)
    782. Dendritic cells and MPIF-1: chemotactic activity and inhibition of endogenous chemokine production by IFN-gamma and CD40 ligation. (PubMed id 10380905)9 Nardelli B....Garotta G. (1999)
    783. Expression of surface antigens during the differentiation of human dendritic cells vs macrophages from blood monocytes in vitro. (PubMed id 10416127)9 Santin A.D....Parham G.P. (1999)
    784. Expression, regulation, and function of B cell-expressed CD154 in germinal centers. (PubMed id 10510350)9 Grammer A.C....Lipsky P.E. (1999)
    785. Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. (PubMed id 9757011)9 Suo Z....Mullan M. (1998)
    786. Analysis of the ligand binding site in Fas (CD95) by site-directed mutagenesis and comparison with TNFR and CD40. (PubMed id 9521690)9 Starling G.C....Bajorath J. (1998)
    787. Low CD83, but normal MHC class II and costimulatory molecule expression, on spleen dendritic cells from HIV+ patients. (PubMed id 9566553)9 McIlroy D....Hosmalin A. (1998)
    788. The N-terminal domain of IkappaB alpha masks the nuclear localization signal(s) of p50 and c-Rel homodimers. (PubMed id 9566883)9 Latimer M....Rice N.R. (1998)
    789. Glucocorticoids inhibit CD40 ligand expression of peripheral CD4+ lymphocytes. (PubMed id 9682002)9 Bischof F. and Melms A. (1998)
    790. The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation. (PubMed id 9469423)9 de Saint-Vis B....Caux C. (1998)
    791. CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line. (PubMed id 9498752)9 Cerutti A....Casali P. (1998)
    792. Cutaneous CD30+ lymphoproliferative disorders: expression of bcl-2 and proteins of the tumor necrosis factor receptor superfamily. (PubMed id 9824099)9 Paulli M....Kadin M.E. (1998)
    793. Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. (PubMed id 9529318)9 Oehler L....Knapp W. (1998)
    794. CD40 ligand and IFN-gamma synergistically restore IL-12 production in HIV-infected patients. (PubMed id 9521075)9 Chougnet C....Shearer G.M. (1998)
    795. Analysis of the promoter elements necessary for IL-4 and anti-CD40 antibody induction of murine Fc epsilon RII (CD23): comparison with the germline epsilon promoter. (PubMed id 8977198)9 Richards M.L. and Katz D.H. (1997)
    796. Modulation of soluble CD40 ligand bioactivity with anti-CD40 antibodies. (PubMed id 9219031)9 Schwabe R.F....Engelmann H. (1997)
    797. CD40 ligation inhibits IL-2 and SAC+IL-2 induced proliferation in chronic lymphocytic leukaemia cells. (PubMed id 9201312)9 SAPderberg O....Nilsson K. (1997)
    798. Induction and differential regulation of bee venom phospholipase A2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells. (PubMed id 9058690)9 Akdis C.A....Blaser K. (1997)
    799. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. (PubMed id 9244201)9 Mach F....Libby P. (1997)
    800. Effect of B-cell receptor engagement on CD40-stimulated B cells. (PubMed id 9486107)9 Schilizzi Leij L.F. (1997)
    801. Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia. (PubMed id 9209268)9 Bonaiuto C....Cassatella M.A. (1997)
    802. Expression of tumor necrosis factor-receptor superfamily members by lung T lymphocytes in interstitial lung disease. (PubMed id 8616567)9 Agostini C....Semenzato G. (1996)
    803. Induction of LFA-1 independent human B cell proliferation and differentiation by binding of CD40 with its ligand. (PubMed id 8675236)9 NAcron S....Darveau A. (1996)
    804. Activation of the Ras signaling pathway by the CD40 receptor. (PubMed id 8816388)9 Gulbins E....Lang F. (1996)
    805. B cell early response gene expression coupled to B cell receptor, CD40 and interleukin-4 receptor co-stimulation: evidence for a role of the egr-2/krox 20 transcription factor in B cell proliferation. (PubMed id 8625972)9 Newton J.S....Murphy J.J. (1996)
    806. Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins. (PubMed id 8676482)9 Su F. and Schneider R.J. (1996)
    807. Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin. (PubMed id 8759752)9 Francisco J.A....Siegall C.B. (1996)
    808. Identification of distinct domains in CD40 involved in B7-1 induction or growth inhibition. (PubMed id 8816387)9 Goldstein M.D. and Watts T.H. (1996)
    809. Classification of mutations in the human CD40 ligand, gp39, that are associated with X-linked hyper IgM syndrome. (PubMed id 16509032)9 Bajorath J....Aruffo A. (1996)
    810. Structural and biological features of the TNF receptor and TNF ligand superfamilies: interactive signals in the pathobiology of Hodgkin's disease. (PubMed id 8836404)9 Gruss H.J....Herrmann F. (1996)
    811. Interferon-gamma and interleukin-10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 (B7-1) expression. (PubMed id 8605933)9 Ozawa H....Tagami H. (1996)
    812. A novel function of CD40: induction of cell death in transformed cells. (PubMed id 8551219)9 Hess S. and Engelmann H. (1996)
    813. CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype. (PubMed id 8551247)9 Galibert L....Rousset F. (1996)
    814. Functions of CD40 and its ligand, gp39 (CD40L). (PubMed id 8809473)9 Laman J.D....Noelle R.J. (1996)
    815. Apoptosis mediated by the TNF-related cytokine and receptor families. (PubMed id 8825415)9 Ware C.F....VanArsdale T.L. (1996)
    816. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. (PubMed id 8698875)9 Koshy M....Crow M.K. (1996)
    817. CD20 and CD40 mediated mitogenic responses in B-lineage acute lymphoblastic leukaemia. (PubMed id 8611444)9 Smiers F.J....Touw I.P. (1996)
    818. Identification of a silencer, enhancer, and basal promoter region in the human CD95 (Fas/APO-1) gene. (PubMed id 7576179)9 Rudert F....Watson J. (1995)
    819. Signaling through CD40 rescues IgE but not IgG or IgA secretion in X- linked immunodeficiency with hyper-IgM. (PubMed id 7532185)9 Saiki O.... Matsuda I. (1995)
    820. Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells. (PubMed id 7561026)9 Cleary A.M....Lederman S. (1995)
    821. Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells. (PubMed id 7542629)9 Loh R.K....Geha R.S. (1995)
    822. Induction of CD40 in promyelocytic HL60 cells cultured with retinoic acid and/or various cytokines. (PubMed id 8690713)9 Shinagawa T....Kanegasaki S. (1995)
    823. RelA is a potent transcriptional activator of the CD2 8 response element within the interleukin 2 promoter. (PubMed id 7623820)9 Lai J.H....Tan T.H. (1995)
    824. CD40-mediated lymphotoxin alpha expression in human B cells is tyrosine kinase dependent. (PubMed id 7589108)9 Worm M. and Geha R.S. (1995)
    825. Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein. (PubMed id 7737295)9 Birkeland M.L....Barclay A.N. (1995)
    826. Functional expression of adhesion receptors and costimulatory molecules by fresh and immortalized B-cell non-Hodgkin's lymphoma cells. (PubMed id 7742541)9 Vyth-Dreese F.A....Hekman A. (1995)
    827. Tumor necrosis factor-alpha facilitates induction of CD80 (B7-1) and CD54 on human B cells by activated T cells: complex regulation by IL-4, IL-10, and CD40L. (PubMed id 7535196)9 Ranheim E.A. and Kipps T.J. (1995)
    828. Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-Rel/p65 heterodimers to a kappa B-like site. (PubMed id 8196620)9 Oeth P.A....Mackman N. (1994)
    829. Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgE. (PubMed id 7523475)9 Loh R.K....Geha R.S. (1994)
    830. Anti-CD40 antibody binding modulates human multiple myeloma clonogenicity in vitro. (PubMed id 7524765)9 Tong A.W....Stone M.J. (1994)
    831. Proliferation and cytogenetic analysis of hairy cell leukemia upon stimulation via the CD40 antigen. (PubMed id 7524766)9 Kluin-Nelemans H.C....Falkenburg J.H. (1994)
    832. Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease. (PubMed id 7522624)9 Gruss H.J....Dower S.K. (1994)
    833. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. (PubMed id 8145033)9 Sallusto F. and Lanzavecchia A. (1994)
    834. A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors. (PubMed id 8095800)9 Peitsch M.C. and Jongeneel C.V. (1993)
    835. Human B cell precursors proliferate and express CD23 after CD40 ligation. (PubMed id 7686210)9 Saeland S....Banchereau J. (1993)
    836. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. (PubMed id 7678782)9 Aruffo A....Neubauer M. (1993)
    837. The role of NF-kappa B1 (p50/p105) gene expression in activation of human blood T-lymphocytes via CD2 and CD28 adhesion molecules. (PubMed id 7905283)9 Costello R....Imbert J. (1993)
    838. Inhibition of LFA-1-dependent human B-cell aggregation induced by CD40 antibodies and interleukin-4 leads to decreased IgE synthesis. (PubMed id 7682536)9 BjAPrck P. and Paulie S. (1993)
    839. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. (PubMed id 7679801)9 Allen R.C.... Spriggs M.K. (1993)
    840. Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors. (PubMed id 1281692)9 Fluckiger A.C....Defrance T. (1992)
    841. Growth factor requirements for the stimulation of germinal center B cells: evidence for an IL-2-dependent pathway of development. (PubMed id 1723294)9 Holder M.J....Gordon J. (1991)
    842. CD40 stimulation provides an IFN-gamma-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production. (PubMed id 1706382)9 Zhang K....Saxon A. (1991)
    843. Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. (PubMed id 2157591)9 Mallett S....Barclay A.N. (1990)
    844. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. (PubMed id 1701824)9 Jabara H.H....Vercelli D. (1990)
    845. Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells. (PubMed id 1702326)9 Uckun F.M....Ledbetter J.A. (1990)
    846. Pericardial fat volume correlates with inflammatory m arkers: the Framingham Heart Study. (PubMed id 19875999)9 Tadros T.M....Benjamin E.J. (2010)
    847. Plasma adiponectin levels in chronic kidney disease p atients: relation with molecular inflammatory profile and metabolic status. (PubMed id 19359150)9 Norata G.D....Catapano A.L. (2010)
    848. B-cell CLL/lymphoma 10 (BCL10) is required for NF-kap paB production by both canonical and noncanonical pathways and for NF-kappaB-in ducing kinase (NIK) phosphorylation. (PubMed id 19897484)9 Bhattacharyya S....Tobacman J.K. (2010)
    849. Tolerogenic dendritic cells generated with different immunosuppressive cytokines induce antigen-specific anergy and regulatory prope rties in memory CD4+ T cells. (PubMed id 20083662)9 Torres-Aguilar H....SA!nchez-Torres C. (2010)
    850. Inhibition of nuclear factor kappa B attenuates tumou r progression in an animal model of renal cell carcinoma. (PubMed id 20037166)9 Morais C....Gobe G. (2010)
    851. Identification of hepatoprotective flavonolignans fro m silymarin. (PubMed id 20231449)9 Polyak S.J....Oberlies N.H. (2010)
    852. High levels of endothelin (ET)-1 and aneurysm diamete r independently predict growth of stable abdominal aortic aneurysms. (PubMed id 19689995)9 Flondell-SitAc D....GottsAoter A. (2010)
    853. IgA and IgG hypogammaglobulinemia in WaldenstrAPm's ma croglobulinemia. (PubMed id 19903677)9 Hunter Z.R....Treon S.P. (2010)
    854. (E)-4-hydroxy-3-methyl-but-2 enyl pyrophosphate-stimu lated Vgamma9Vdelta2 T cells possess T helper type 1-promoting adjuvant activit y for human monocyte-derived dendritic cells. (PubMed id 20306041)9 Dunne M.R....Doherty D.G. (2010)
    855. NF-kappaB function in the human myometrium during pre gnancy and parturition. (PubMed id 20503182)9 Cookson V.J. and Chapman N.R. (2010)
    856. Protective effect of resin adsorption on septic plasm a-induced tubular injury. (PubMed id 20064258)9 Cantaluppi V....Camussi G. (2010)
    857. Activation of mixed glia by Abeta-specific Th1 and Th 17 cells and its regulation by Th2 cells. (PubMed id 20060887)9 McQuillan K....Mills K.H. (2010)
    858. Cytokine expression in placenta-derived mesenchymal s tem cells in patients with pre-eclampsia and normal pregnancies. (PubMed id 19819721)9 Hwang J.H....Oh M.J. (2010)
    859. Different responsiveness of endothelial cells to vasc ular endothelial growth factor and basic fibroblast growth factor added to cult ure media under gravity and simulated microgravity. (PubMed id 20001221)9 Grimm D....Baatout S. (2010)
    860. The role of costimulatory molecules in allergic disea se and asthma. (PubMed id 19786798)9 Lombardi V....Akbari O. (2010)
    861. Interaction of T-cell and antigen presenting cell co- stimulatory genes in childhood IgE. (PubMed id 19574333)9 Bottema R.W....Kerkhof M. (2010)
    862. Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantatio n. (PubMed id 20156509)9 Bodonyi-Kovacs G....Pavlakis M. (2010)
    863. Gene discovery in rheumatoid arthritis highlights the CD40/NF-kappaB signaling pathway in disease pathogenesis. (PubMed id 20192992)9 Criswell L.A. (2010)
    864. Induction of type 2 T helper cell allergen tolerance by IL-10-differentiated regulatory dendritic cells. (PubMed id 19372244)9 Li X....Gordon J.R. (2010)
    865. Increased levels of resistin in rotating shift worker s: a potential mediator of cardiovascular risk associated with circadian misali gnment. (PubMed id 20106477)9 BurgueA+o A....Pirola C.J. (2010)
    866. Soluble CD40 ligand impairs the function of periphera l blood angiogenic outgrowth cells and increases neointimal formation after art erial injury. (PubMed id 20048211)9 Hristov M....Weber C. (2010)
    867. Toll-like receptors 2 and 4 and the cryopyrin inflamm asome in normal pregnancy and pre-eclampsia. (PubMed id 20002372)9 Xie F....von Dadelszen P. (2010)
    868. Novel therapeutic targets for multiple myeloma. (PubMed id 20222797)9 Mahindra A....Raje N. (2010)
    869. Neuronal apoptosis is inhibited by cord blood stem ce lls after spinal cord injury. (PubMed id 19469692)9 Dasari V.R....Rao J.S. (2009)
    870. Regulation and function of NF-kappaB transcription factors in the immune system. (PubMed id 19302050)9 Vallabhapurapu S. and Karin M. (2009)
    871. RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo. (PubMed id 19347041)9 Tian W. and Liou H.C. (2009)
    872. NF-kappaB activation through the alternative pathway correlates with chemoresistance and poor survival in extranodal NK/T-cell lymph oma, nasal type. (PubMed id 19395464)9 Liu X....Guo Y. (2009)
    873. Signaling defects and functional impairment in T-cell s from cervical cancer patients. (PubMed id 20025546)9 Cheriyan V.T....Balaram P. (2009)
    874. Metallic haptens induce differential phenotype of human dendritic cells through activation of mitogen-activated protein kinase and NF-kappaB pathways. (PubMed id 19101624)9 Antonios D....Pallardy M. (2009)
    875. Naive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules. (PubMed id 19201847)9 Buhtoiarov I.N....Sondel P.M. (2009)
    876. Angiotensin II modulates CD40 expression in vascular smooth muscle cells. (PubMed id 18785879)9 Souza H.P....Tostes R.C. (2009)
    877. Future novel single agent and combination therapies. (PubMed id 20010171)9 Cirstea D....Raje N. (2009)
    878. Neutralization of granulocyte macrophage colony-stimu lating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease. (PubMed id 19617638)9 Manczak M....Reddy P.H. (2009)
    879. Collapse of the CD27+ B-cell compartment associated w ith systemic plasmacytosis in patients with advanced melanoma and other cancers . (PubMed id 19549767)9 Carpenter E.L....Vonderheide R.H. (2009)
    880. [Preparation and characterization of a mouse anti-hum an CD40 mutant monoclonal antibody] (PubMed id 19811740)9 Zheng S.D....Zhang X.G. (2009)
    881. Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene. (PubMed id 19164932)9 Esendagli G....Guc D. (2009)
    882. Ligation or cross-linking of CD40 has different effec ts on AGS gastric cancer cells. (PubMed id 19604505)9 Qi C.J....Zhang X.G. (2009)
    883. Targeting CD40 in WaldenstrAPm's macroglobulinemia. (PubMed id 19362983)9 Lee M. and Advani R. (2009)
    884. The humanized CD40 antibody SGN-40 demonstrates pre-clinical activity that is enhanced by lenalidomide in chronic lymphocytic leukaemia. (PubMed id 19183192)9 Lapalombella R....Byrd J.C. (2009)
    885. REL, encoding a member of the NF-kappaB family of tra nscription factors, is a newly defined risk locus for rheumatoid arthritis. (PubMed id 19503088)9 Gregersen P.K....Siminovitch K.A. (2009)
    886. Doxorubicin enhances CD4(+) T-cell immune responses b y inducing expression of CD40 ligand and 4-1BB. (PubMed id 19778641)9 Park J.Y....Kim D. (2009)
    887. A rapid flow cytometric technique for the detection o f platelet-monocyte complexes, activated platelets and platelet-derived micropa rticles. (PubMed id 18384393)9 Pearson L....Baker R. (2009)
    888. The biological functions of NF-kappaB1 (p50) and its potential as an anti-cancer target. (PubMed id 19519322)9 Yu Y....Huang C. (2009)
    889. Lenalidomide (Revlimid) administration at symptom ons et is neuroprotective in a mouse model of amyotrophic lateral sclerosis. (PubMed id 19733563)9 Neymotin A....Kiaei M. (2009)
    890. Liver X receptors control IgE expression in B cells. (PubMed id 19380774)9 Heine G....Worm M. (2009)
    891. Histamine inhibits advanced glycation end products-in duced adhesion molecule expression on human monocytes. (PubMed id 19567778)9 Wake H....Nishibori M. (2009)
    892. Inflammatory biomarkers in coronary artery disease. (PubMed id 19477372)9 Zakynthinos E. and Pappa N. (2009)
    893. Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability. (PubMed id 19087197)9 Pizzi M....Spano P. (2009)
    894. Altered bone marrow dendritic cell cytokine production to toll-like receptor and CD40 ligation during chronic feline immunodeficiency virus infection. (PubMed id 18775027)9 Lehman T.L....Avery P.R. (2009)
    895. Linking innate and adaptive immunity: human Vgamma9Vd elta2 T cells enhance CD40 expression and HMGB-1 secretion. (PubMed id 19841752)9 Kalyan S. and Chow A.W. (2009)
    896. NF-kappaB dimers in the regulation of neuronal surviv al. (PubMed id 19607980)9 Sarnico I....Pizzi M. (2009)
    897. Autoantibodies to beta1-adrenoceptors in human chroni c periodontitis induce overexpression of fibroblast CD40 and trigger prostaglan din E2 generation. (PubMed id 18973525)9 Sterin-Borda L....Borda E. (2009)
    898. SDF-1alpha up-regulates interleukin-6 through CXCR4, PI3K/Akt, ERK, and NF-kappaB-dependent pathway in microglia. (PubMed id 19285061)9 Lu D.Y....Fu W.M. (2009)
    899. Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. (PubMed id 19417017)9 Bonehill A....Thielemans K. (2009)
    900. Relation of multiple inflammatory biomarkers to incid ent atrial fibrillation. (PubMed id 19576326)9 Schnabel R.B....Benjamin E.J. (2009)
    901. Active uptake of dendritic cell-derived exovesicles b y epithelial cells induces the release of inflammatory mediators through a TNF- alpha-mediated pathway. (PubMed id 19628765)9 Obregon C....Nicod L.P. (2009)
    902. Unraveling the genetics of complex diseases: suscepti bility genes for rheumatoid arthritis and psoriasis. (PubMed id 19446472)9 Li Y. and Begovich A.B. (2009)
    903. STAT6 activation by Toxoplasma gondii infection induc es the expression of Th2 C-C chemokine ligands and B clade serine protease inhi bitors in macrophage. (PubMed id 19655172)9 Ahn H.J....Nam H.W. (2009)
    904. Inducement of mitogen-activated protein kinases in frozen shoulders. (PubMed id 19214689)9 Kanbe K....Chen Q. (2009)
    905. Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways. (PubMed id 19558546)9 Requena P....MartA-nez-Augustin O. (2009)
    906. Glucocorticoids suppress NF-kappaB activation induced by LPS and PGN in paranasal sinus epithelial cells. (PubMed id 19936369)9 Nishi Y....Hirakawa K. (2009)
    907. Costimulation signals for memory CD8+ T cells during viral infections. (PubMed id 20121696)9 Duttagupta P.A....Katsikis P.D. (2009)
    908. Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts. (PubMed id 19288477)9 Hou C.H....Tang C.H. (2009)
    909. Prostaglandin E2 inhibits advanced glycation end prod uct-induced adhesion molecule expression, cytokine production, and lymphocyte p roliferation in human peripheral blood mononuclear cells. (PubMed id 19700629)9 Takahashi H.K....Nishibori M. (2009)
    910. Nuclear factor kappa B subunit p50 promotes melanoma angiogenesis by upregulating interleukin-6 expression. (PubMed id 18942706)9 Karst A.M....Li G. (2009)
    911. Differential effects of hepatitis C virus JFH1 on human myeloid and plasmacytoid dendritic cells. (PubMed id 19297478)9 Liang H....Anthony D.D. (2009)
    912. Human IgA-inducing protein from dendritic cells induces IgA production by naive IgD+ B cells. (PubMed id 19201837)9 Endsley M.A....Estes D.M. (2009)
    913. Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects. (PubMed id 19283894)9 Margolles-Clark E....Buchwald P. (2009)
    914. Role of the mannose receptor in a murine model of Cryptococcus neoformans infection. (PubMed id 18391001)9 Dan J.M....Levitz S.M. (2008)
    915. Differential effects of allergens and irritants on early differentiating monocyte-derived dendritic cells. (PubMed id 18424372)9 Furio L....Peguet-Navarro J. (2008)
    916. Beyond hemostasis: the role of platelets in inflammation, malignancy and infection. (PubMed id 18537597)9 McNicol A. and Israels S.J. (2008)
    917. Jun D cooperates with p65 to activate the proximal kappaB site of the cyclin D1 promoter: role of PI3K/PDK-1. (PubMed id 18174238)9 Toualbi-Abed K....Bernuau D. (2008)
    918. Expression of heat shock protein receptors on fibroblast-like synovial cells derived from rheumatoid arthritis-affected joints. (PubMed id 18231792)9 Hromadnikova I....Sosna A. (2008)
    919. CD8+CD28-, suppressive T cells in systemic lupus erythematosus. (PubMed id 18625635)9 Tulunay A....Eksioglu-Demiralp E. (2008)
    920. Proteinase-activated receptor-1-triggered activation of tumor progression locus-2 promotes actin cytoskeleton reorganization and cell migration. (PubMed id 18339866)9 Hatziapostolou M....Tsichlis P.N. (2008)
    921. Thrombin regulates CD40 expression in microglial cells. (PubMed id 18418252)9 Weinstein J.R....MAPller T. (2008)
    922. Immune response following miltefosine therapy in a patient with post-kala-azar dermal leishmaniasis. (PubMed id 18639311)9 Ansari N.A....Salotra P. (2008)
    923. Association of low-grade inflammation and platelet activation in patients with hypertension with microalbuminuria. (PubMed id 17988217)9 Ferroni P....DavA- G. (2008)
    924. A CD40-CD154 interaction in tissue fibrosis. (PubMed id 18975310)9 Kawai M....Kuwana M. (2008)
    925. Induction of high expression of CCR7 and high production of IL-12 in human monocyte-derived dendritic cells by a new bacterial component: LCOS 1013. (PubMed id 18602060)9 Gillet-Hladky S....Rigal D. (2008)
    926. IFN-gamma arms human dendritic cells to perform multiple effector functions. (PubMed id 18209042)9 Frasca L....Ausiello C.M. (2008)
    927. Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures. (PubMed id 18959781)9 Adrien D....Marcus L. (2008)
    928. Immune properties of human umbilical cord Wharton's jelly-derived cells. (PubMed id 18703664)9 Weiss M.L....McIntosh K.R. (2008)
    929. Distribution and clinical significance of blood dendritic cells in children with juvenile idiopathic arthritis. (PubMed id 17965117)9 Smolewska E....Smolewski P. (2008)
    930. Comparison of human B cell activation by TLR7 and TLR9 agonists. (PubMed id 18652679)9 Hanten J.A....Birmachu W. (2008)
    931. T-cell costimulation and coinhibition in atherosclerosis. (PubMed id 19028921)9 Gotsman I....Lichtman A.H. (2008)
    932. Nuclear factor-kappaB mediates the inhibitory effects of tumor necrosis factor-alpha on growth hormone-inducible gene expression in liver. (PubMed id 18719026)9 Buzzelli M.D....Cooney R.N. (2008)
    933. Novel biomarkers in early diagnosis of acute myocardial infarction compared with cardiac troponin T. (PubMed id 18682444)9 McCann C.J....Adgey J.A. (2008)
    934. The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine. (PubMed id 19088025)9 Hewamana S....Pepper C. (2008)
    935. Systemic inflammation and COPD: the Framingham Heart Study. (PubMed id 17908709)9 Walter R.E....Benjamin E.J. (2008)
    936. TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients. (PubMed id 18684674)9 Wu P....Cao X. (2008)
    937. Clinical implications of elevated serum interleukin-6, soluble CD40 ligand, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in patients with acute ST-segment elevation myocardial infarction. (PubMed id 18781600)9 Tan J....Fan Z.X. (2008)
    938. CD40 activation in human pancreatic islets and ductal cells. (PubMed id 18661119)9 Klein D....Pastori R.L. (2008)
    939. Monocyte-derived dendritic cells as antigen-presentin g cells in T-cell proliferation and cytokine production. (PubMed id 18615247)9 Sung S.S. (2008)
    940. Peroxisome proliferator-activated receptor-gamma1 gene therapy attenuates atherosclerosis and stabilizes plaques in apolipoprotein E-deficient mice. (PubMed id 18302511)9 Hu Q....Zhang Y. (2008)
    941. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. (PubMed id 18997792)9 Vallabhapurapu S....Karin M. (2008)
    942. The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells. (PubMed id 18606639)9 Spirig R....Rieben R. (2008)
    943. Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. (PubMed id 18373164)9 Futagami S....Sakamoto C. (2008)
    944. Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale. (PubMed id 18391760)9 Kaka A.S....Leen A.M. (2008)
    945. Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages. (PubMed id 18358739)9 Kent L....Singh D. (2008)
    946. 1,25-dihydroxyvitamin D(3) promotes IL-10 production in human B cells. (PubMed id 18651709)9 Heine G....Worm M. (2008)
    947. Deficiency of Act1, a critical modulator of B cell function, leads to development of SjAPgren's syndrome. (PubMed id 18624351)9 Qian Y....Li X. (2008)
    948. The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP. (PubMed id 18556415)9 Goval Leval L. (2008)
    949. Onychomadesis in a patient with immunoglobulin class switch recombination deficiency. (PubMed id 18322312)9 Safari M....Hammarstrom L. (2008)
    950. Preclinical assessment of therapeutic antibodies against human CD40 and human interleukin-12/23p40 in a nonhuman primate model of multiple sclerosis. (PubMed id 18075274)9 't Hart B.A....Laman J.D. (2008)
    951. The modulatory effects of lipopolysaccharide-stimulated B cells on differential T-cell polarization. (PubMed id 18355243)9 Xu H....Chua K.Y. (2008)
    952. IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. (PubMed id 18566370)9 Turnquist H.R....Thomson A.W. (2008)
    953. Activation of p300 histone acetyltransferase activity is an early endothelial response to laminar shear stress and is essential for stimulation of endothelial nitric-oxide synthase mRNA transcription. (PubMed id 18397880)9 Chen W....Harrison D.G. (2008)
    954. Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor. (PubMed id 17710396)9 Liu C.C....Chu R.M. (2008)
    955. NF-kappa B genes have a major role in inflammatory breast cancer. (PubMed id 18248671)9 Lerebours F....Bieche I. (2008)
    956. Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations. (PubMed id 18275936)9 Mackenzie G.G....Oteiza P.I. (2008)
    957. COX-2 and CCR2 induced by CD40 ligand and MCP-1 are linked to VEGF production in endothelial cells. (PubMed id 18093816)9 Futagami S....Sakamoto C. (2008)
    958. Negative regulators of angiogenesis in inflammatory bowel disease: thrombospondin in the spotlight. (PubMed id 18334836)9 Danese S. (2008)
    959. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. (PubMed id 18426996)9 Schnabel R....Benjamin E.J. (2008)
    960. Complete rejection of a T-cell lymphoma due to synerg ism of T-cell receptor costimulatory molecules, CD80, CD40L, and CD40. (PubMed id 18155328)9 Ruybal P....Mongini C. (2008)
    961. JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin. (PubMed id 18507870)9 Park H.J....Hong J.T. (2008)
    962. CD40L and IL-4 stimulation of acute lymphoblastic leukemia cells results in upregulation of mRNA level of FLICE--an important component of apoptosis. (PubMed id 17378240)9 l/uczynski W....Wieczorek M. (2007)
    963. A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair. (PubMed id 17485519)9 PAcron S....Durandy A. (2007)
    964. Janus faces of microglia in multiple sclerosis. (PubMed id 17383006)9 Sanders P. and De Keyser J. (2007)
    965. CD154-stimulated GM-CSF release by vascular smooth muscle cells elicits monocyte activation--role in atherogenesis. (PubMed id 17619839)9 Stojakovic M....Hecker M. (2007)
    966. Elevation of activated platelet-dependent chemokines and soluble cell adhesion molecules in patients with hematologic malignancies and high levels of beta-D-glucan. (PubMed id 18332612)9 Nomura S....Urase F. (2007)
    967. Differential effects of somatostatin on circulating tissue factor procoagulant activity and protein. (PubMed id 17213471)9 Boden G....Rao A.K. (2007)
    968. Presence and phenotype of dendritic cells in uveal melanoma. (PubMed id 17347328)9 Polak M.E....Cree I.A. (2007)
    969. Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway. (PubMed id 17938270)9 Lee S.H....Hong J.T. (2007)
    970. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. (PubMed id 17692804)9 Annunziata C.M....Staudt L.M. (2007)
    971. Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands. (PubMed id 18334250)9 Martinson J.A....Landay A.L. (2007)
    972. Altered signal transduction in SLE T cells. (PubMed id 17586862)9 Tenbrock K....Tsokos G.C. (2007)
    973. Anthocyanin prevents CD40-activated proinflammatory signaling in endothelial cells by regulating cholesterol distribution. (PubMed id 17158355)9 Xia M....Ye Q. (2007)
    974. Endothelin-1 induces functionally active CD40 protein via nuclear factor-kappaB in human vascular smooth muscle cells. (PubMed id 17507309)9 Browatzki M....Kranzhofer R. (2007)
    975. Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling. (PubMed id 17614141)9 Kantor A.B....Goelz S.E. (2007)
    976. Ultrasound induces cyclooxygenase-2 expression through integrin, integrin-linked kinase, Akt, NF-kappaB and p300 pathway in human chondrocytes. (PubMed id 17692505)9 Hsu H.C....Tang C.H. (2007)
    977. The immunosuppressive effects of nicotine during human mixed lymphocyte reaction. (PubMed id 17254563)9 Takahashi H.K....Nishibori M. (2007)
    978. Antithymocyte globulins suppress dendritic cell function by multiple mechanisms. (PubMed id 17318082)9 Naujokat C....Daniel V. (2007)
    979. Inflammatory markers of atherosclerosis are decreased after moderate consumption of cava (sparkling wine) in men with low cardiovascular risk. (PubMed id 17885011)9 VA!zquez-Agell M....Estruch R. (2007)
    980. Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males. (PubMed id 17043800)9 Bonaterra G.A....Kinscherf R. (2007)
    981. TRAF proteins in CD40 signaling. (PubMed id 17633023)9 Bishop G.A....Kraus Z.J. (2007)
    982. Mechanisms of disease: regulation of RANTES (CCL5) in renal disease. (PubMed id 17322928)9 Krensky A.M. and Ahn Y.T. (2007)
    983. CD40.FasL inhibits human T cells: evidence for an auto-inhibitory loop-back mechanism. (PubMed id 17314083)9 Dranitzki-Elhalel M....Tykocinski M.L. (2007)
    984. The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. (PubMed id 17369021)9 Jacobson E.M. and Tomer Y. (2007)
    985. OX40 gene expression is up-regulated by chromatin remodeling in its promoter region containing Sp1/Sp3, YY1, and NF-kappa B binding sites. (PubMed id 17641042)9 Tone Y....Tone M. (2007)
    986. The clinical grade maturation cocktail monophosphoryl lipid A plus IFNgamma generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization. (PubMed id 17719152)9 Ten Brinke A....van Ham S.M. (2007)
    987. Cord blood CD34+ cells cultured with FLT3L, stem cell factor, interleukin-6, and IL-3 produce CD11c+CD1a-/c- myeloid dendritic cells. (PubMed id 17999605)9 Fadilah S.A....Hart D.N. (2007)
    988. Expression of dendritic cell markers on cultured neutrophils and its modulation by anti-apoptotic and pro-apoptotic compounds. (PubMed id 17934331)9 Park H.Y....Kwak J.Y. (2007)
    989. Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells. (PubMed id 17083604)9 Naujokat C....Daniel V. (2007)
    990. Physiological roles and mechanisms of signaling by TRAF2 and TRAF5. (PubMed id 17633015)9 Au P.Y. and Yeh W.C. (2007)
    991. Human immunodeficiency virus type 1-associated CD40 ligand transactivates B lymphocytes and promotes infection of CD4+ T cells. (PubMed id 17392362)9 Martin G....Tremblay M.J. (2007)
    992. Increased serum levels of circulating CD40 ligand in patients with bullous pemphigoid: preliminary results. (PubMed id 17823512)9 Watanabe R....Tamaki K. (2007)
    993. Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study). (PubMed id 17531588)9 Thakore A.H....O'Donnell C.J. (2007)
    994. Phenotypic alterations and cytokine production in THP-1 cells in response to allergens. (PubMed id 17118622)9 Miyazawa M....Suzuki H. (2007)
    995. Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus. (PubMed id 17530637)9 Dieker J.W....van der Vlag J. (2007)
    996. Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis? (PubMed id 18079224)9 Choudhury A....Lip G.Y. (2007)
    997. Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells. (PubMed id 17513725)9 Wang J....Beg A.A. (2007)
    998. Nuclear factor kappa-B p50 and p65 subunits expression in dementia with Lewy bodies. (PubMed id 17442064)9 SaldaA+a M....Marin C. (2007)
    999. Monocyte-derived dendritic cell function in chronic hepatitis C is impaired at physiological numbers of dendritic cells. (PubMed id 17362265)9 MacDonald A.J....Rosenberg W.M. (2007)
    1000. Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4. (PubMed id 18481208)9 Lee R.L....Gold M.R. (2007)
    1001. Human platelets can activate peripheral blood B cells and increase production of immunoglobulins. (PubMed id 17656005)9 Cognasse F....Garraud O. (2007)
    1002. Roles of TRAF6 in CD40 signaling. (PubMed id 17917059)9 Hostager B.S. (2007)
    1003. Apolipoprotein E deficiency enhances the antigen-presenting capacity of Schwann cells. (PubMed id 17357152)9 Duan R.S....Zhu J. (2007)
    1004. Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. (PubMed id 17617622)9 Tang C.H....Chen Y.F. (2007)
    1005. Post-prandial endothelial dysfunction in hypertriglyceridemic subjects: molecular mechanisms and gene expression studies. (PubMed id 17055512)9 Norata G.D....Catapano A.L. (2007)
    1006. Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. (PubMed id 17482516)9 Takahashi H.K....Nishibori M. (2007)
    1007. Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus. (PubMed id 17292732)9 Tesauro M....Quon M.J. (2007)
    1008. Mechanisms of polymorphonuclear neutrophil-mediated induction of HIV-1 replication in macrophages during pulmonary tuberculosis. (PubMed id 17396999)9 Hoshino Y....Weiden M. (2007)
    1009. Histamine enhances the production of human beta-defensin-2 in human keratinocytes. (PubMed id 17928537)9 Kanda N. and Watanabe S. (2007)
    1010. Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function. (PubMed id 17452522)9 Summers-DeLuca L.E....Gommerman J.L. (2007)
    1011. Delayed redistribution of CD27, CD40 and CD80 positive B cells and the impaired in vitro immunoglobulin production in patients with non-Hodgkin lymphoma after rituximab treatment as an adjuvant to autologous stem cell transplantation. (PubMed id 17456057)9 Nishio M....Koike T. (2007)
    1012. Platelet expression of CD40/CD40 ligand and its relation to inflammatory markers and adhesion molecules in patients with atrial fibrillation. (PubMed id 17392495)9 HammwAPhner M....Goette A. (2007)
    1013. CD40 expression identifies a prognostically favourable subgroup of diffuse large B-cell lymphoma. (PubMed id 17786713)9 Linderoth J....Cavallin-StAYhl E. (2007)
    1014. Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. (PubMed id 17068485)9 Lebre Jong E.C. (2007)
    1015. Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway. (PubMed id 17911635)9 Tang C.H....Fu W.M. (2007)
    1016. GCSF receptor regulates antigen uptake and expression of cytokines and costimulatory molecules in dendritic cells. (PubMed id 16574228)9 Geng D....She J.X. (2007)
    1017. Measuring soluble CD40 ligand:interleukin-10 ratio as a prognostic marker in acute myocardial infarction: yet another prognostic biomarker? (PubMed id 17610938)9 Jessani S. and Lip G.Y. (2007)
    1018. Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling. (PubMed id 17442935)9 Sanderson J.P....Park B.K. (2007)
    1019. Dendritic cells suppress IgE production in B cells. (PubMed id 17208926)9 Obayashi K....Koyasu S. (2007)
    1020. Circulating myeloid dendritic cell directly isolated from patients with chronic myelogenous leukemia are functional and carry the bcr-abl translocation. (PubMed id 16527350)9 Orsini E....Foa R. (2006)
    1021. Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway. (PubMed id 16493050)9 Slukvin I.I....Choi K.D. (2006)
    1022. The proportion of CD40+ mucosal macrophages is increased in inflammatory bowel disease whereas CD40 ligand (CD154)+ T cells are relatively decreased, suggesting differential modulation of these costimulatory molecules in human gut lamina propria. (PubMed id 17075342)9 Carlsen H.S....Brandtzaeg P. (2006)
    1023. Circulating inflammatory mediators and organ dysfunction after cardiovascular surgery with cardiopulmonary bypass: a prospective observational study. (PubMed id 16542504)9 de MendonAsa-Filho H.T....Castro-Faria-Neto H.C. (2006)
    1024. Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression. (PubMed id 16709811)9 Shorts L....Wiltrout R.H. (2006)
    1025. Protective effect of tanshinone IIA on human umbilica l vein endothelial cell injured by hydrogen peroxide and its mechanism. (PubMed id 16797899)9 Lin R....Han C.J. (2006)
    1026. Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB. (PubMed id 16214042)9 Tzimas C....Hatzivassiliou E.G. (2006)
    1027. Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation. (PubMed id 16981910)9 Cantaluppi V....Camussi G. (2006)
    1028. Comparison by flow cytometry of immune changes induce d in human monocyte-derived dendritic cells upon infection with dengue 2 live-a ttenuated vaccine or 16681 parental strain. (PubMed id 16420604)9 Sanchez V....Guy B. (2006)
    1029. Early growth response-1 is required for CD154 transcription. (PubMed id 16393964)9 Cron R.Q....Crow M.K. (2006)
    1030. Follicular dendritic cells are related to bone marrow stromal cell progenitors and to myofibroblasts. (PubMed id 16785523)9 Munoz-Fernandez R....Olivares E.G. (2006)
    1031. Uptake characteristics of NGR-coupled stealth PEI/pDNA nanoparticles loaded with PLGA-PEG-PLGA tri-block copolymer for targeted delivery to human monocyte-derived dendritic cells. (PubMed id 16860501)9 Moffatt S. and Cristiano R.J. (2006)
    1032. Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis. (PubMed id 16513684)9 Stasiolek M....Selmaj K. (2006)
    1033. Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes. (PubMed id 16412852)9 Lenderink T....Boersma E. (2006)
    1034. Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome. (PubMed id 17027571)9 Wang T.D....Lee Y.T. (2006)
    1035. CD40 stimulation induces differentiation of acute lymphoblastic leukemia cells into dendritic cells. (PubMed id 16733557)9 LuczyA8ski W....SzymaA8ski M. (2006)
    1036. The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development. (PubMed id 16970925)9 Dejardin E. (2006)
    1037. Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA. (PubMed id 16680372)9 Tian F....Xue L.X. (2006)
    1038. DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes. (PubMed id 16839201)9 Rappocciolo G....Rinaldo C.R. (2006)
    1039. Abnormal soluble CD40 ligand and C-reactive protein concentrations in hypertension: relationship to indices of angiogenesis. (PubMed id 16331109)9 Patel J.V....Lip G.Y. (2006)
    1040. Luteolin, a flavonoid, inhibits AP-1 activation by basophils. (PubMed id 16343431)9 Hirano T....Tanaka T. (2006)
    1041. Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria. (PubMed id 16857732)9 Ben Nasr A....Klimpel G.R. (2006)
    1042. Cardiac function, inflammatory mediators and mortality in critical limb ischemia. (PubMed id 17022379)9 Barani J....GottsAoter A. (2006)
    1043. Enhanced expression of mRNA for nuclear factor kappaB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis. (PubMed id 16519794)9 Hirohata S....Chiorazzi N. (2006)
    1044. Differential expression and activation of NF-kappaB family proteins during oral carcinogenesis: Role of high risk human papillomavirus infection. (PubMed id 16998793)9 Mishra A....Das B.C. (2006)
    1045. Characterization of the expanded T-cell populations in patients with Wegener's granulomatosis. (PubMed id 16918819)9 Giscombe R....Lefvert A.K. (2006)
    1046. Effect of nicotine on IL-18-initiated immune response in human monocytes. (PubMed id 16966384)9 Takahashi H.K....Nishibori M. (2006)
    1047. GM-CSF priming of human monocytes is dependent on ERK1/2 activation. (PubMed id 16420740)9 Lendemans S....FlohAc S. (2006)
    1048. Mycobacterium tuberculosis upregulates coreceptors CCR5 and CXCR4 while HIV modulates CD14 favoring concurrent infection. (PubMed id 16438645)9 Rosas-Taraco A.G....Salinas-Carmona M.C. (2006)
    1049. A novel mechanism of nuclear factor-kappaB regulation by adenoviral protein 14.7K. (PubMed id 16423054)9 Carmody R.J....Chen Y.H. (2006)
    1050. Chronic inflammation, immune response, and infection in abdominal aortic aneurysms. (PubMed id 16414293)9 Lindholt J.S. and Shi G.P. (2006)
    1051. Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR- and CD40-specific stimuli in a MyD88/TLR2-dependent manner. (PubMed id 16818783)9 Turner J.D....Taylor M.J. (2006)
    1052. Increased endocytic activity in monocyte-derived dendritic cells in patients with psoriasis vulgaris. (PubMed id 16567867)9 Zhu K.J....Ye J. (2006)
    1053. The immunobiological development of human bone marrow mesenchymal stem cells in the course of neuronal differentiation. (PubMed id 17448455)9 Liu C.T....Xie M. (2006)
    1054. A CD40-CD95L fusion protein interferes with CD40L-induced prosurvival signaling and allows membrane CD40L-restricted activation of CD95. (PubMed id 16924474)9 Assohou-Luty C....Wajant H. (2006)
    1055. CD11c+ blood dendritic cells induce antigen-specific cytotoxic T lymphocytes with similar efficiency compared to monocyte-derived dendritic cells despite higher levels of MHC class I expression. (PubMed id 17063122)9 Radford K.J....Hart D.N. (2006)
    1056. Interleukin-7 induced immunopathology in arthritis. (PubMed id 17038478)9 Hartgring S.A....van Roon J.A. (2006)
    1057. Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K. (PubMed id 16897814)9 Benson R.J....Bishop G.A. (2006)
    1058. CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2. (PubMed id 15970430)9 Ahmed-Choudhury J....Afford S.C. (2006)
    1059. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. (PubMed id 17145890)9 Saccani A....Sica A. (2006)
    1060. CD40 ligand increases expression of its receptor CD40 in human coronary artery endothelial cells. (PubMed id 16904975)9 Chai H....Chen C. (2006)
    1061. A time course study of immunological responses in Trichuris suis infected pigs demonstrates induction of a local type 2 response associated with worm burden. (PubMed id 16750534)9 Kringel H....Roepstorff A. (2006)
    1062. [Preparation and identification of soluble trimeric CD40-isoleucine zipper fusion protein] (PubMed id 16755930)9 Xu L.H....He X.H. (2006)
    1063. Comparison of effects of bare metal versus drug-eluting stent implantation on biomarker levels following percutaneous coronary intervention for non-ST-elevation acute coronary syndrome. (PubMed id 16679086)9 Gibson C.M....Morrow D.A. (2006)
    1064. Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-gamma. (PubMed id 16461742)9 Doni A....Mantovani A. (2006)
    1065. Regulation of dendritic cell differentiation by vasoactive intestinal peptide: therapeutic applications on autoimmunity and transplantation. (PubMed id 17192565)9 Chorny A....Delgado M. (2006)
    1066. Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes. (PubMed id 16505242)9 Devaraj S....Jialal I. (2006)
    1067. Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells. (PubMed id 16317058)9 Norata G.D....Catapano A.L. (2006)
    1068. [Heterogeneity and function of human B lymphocytes] (PubMed id 17156729)9 Jacquot S. and Boyer O. (2006)
    1069. Release of potential immunomodulatory factors during platelet storage. (PubMed id 16836566)9 Cognasse F....Garraud O. (2006)
    1070. Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor. (PubMed id 15720433)9 Rahim S.S....Mukhopadhyay S. (2005)
    1071. Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. (PubMed id 16291659)9 Oki S....Miyake S. (2005)
    1072. Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection. (PubMed id 15688034)9 Fan S....Rosen E.M. (2005)
    1073. CD40-dependent activation of phosphatidylinositol 3-kinase/AKT pathway inhibits apoptosis of human cultured mesangial cells induced by oxidized LDL. (PubMed id 15888255)9 Deambrosis I....Bussolati B. (2005)
    1074. Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis. (PubMed id 15914563)9 Ruiz-Ballesteros E....Piris M.A. (2005)
    1075. Mechanisms of cell signaling and inflammation in Alzheimer's disease. (PubMed id 15853747)9 Ho G.J....Masliah E. (2005)
    1076. Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis. (PubMed id 15653020)9 Heeschen C....Zeiher A.M. (2005)
    1077. Resolution of inflammation: prostaglandin E2 dissociates nuclear trafficking of individual NF-kappaB subunits (p65, p50) in stimulated rheumatoid synovial fibroblasts. (PubMed id 16272352)9 Gomez P.F....Abramson S.B. (2005)
    1078. TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs. (PubMed id 15708970)9 Hauer J....Engelmann H. (2005)
    1079. Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells. (PubMed id 15674425)9 Farahani M....Chen H. (2005)
    1080. Expression of adhesion molecules and RANTES in kidney transplant from nonheart-beating donors. (PubMed id 15730495)9 Gomez del Moral M....Martinez-Naves E. (2005)
    1081. NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity. (PubMed id 15818410)9 Pizzi M....Spano P.F. (2005)
    1082. Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40. (PubMed id 16166310)9 Law C.L....Grewal I.S. (2005)
    1083. Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. (PubMed id 15611226)9 Hill S.C....Eliopoulos A.G. (2005)
    1084. CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo. (PubMed id 16186418)9 Davis B. and Zou M.H. (2005)
    1085. Soluble CD40 ligand levels in patients with hypertension. (PubMed id 16303639)9 Sonmez A....Kocar I.H. (2005)
    1086. CD1d ligation on human monocytes directly signals rapid NF-kappaB activation and production of bioactive IL-12. (PubMed id 16091469)9 Yue S.C....Exley M.A. (2005)
    1087. LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3. (PubMed id 16009714)9 Wu S....Ely K.R. (2005)
    1088. Phenotypic characterisation of alveolar macrophages and peripheral blood monocytes in COPD. (PubMed id 15802338)9 Pons A.R....AgustA- A.G. (2005)
    1089. Strength of TRAF6 signalling determines osteoclastogenesis. (PubMed id 15678156)9 Kadono Y....Choi Y. (2005)
    1090. Inhibitory activity of polyhydroxycarboxylate chelators against recombinant NF-kappaB p50 protein-DNA binding. (PubMed id 15788163)9 Sharma R.K....Otsuka M. (2005)
    1091. Lovastatin reduces nuclear factor kappaB activation i nduced by C-reactive protein in human vascular endothelial cells. (PubMed id 16141529)9 Lin R....Wang W. (2005)
    1092. Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages. (PubMed id 16207716)9 Billiet L....Rouis M. (2005)
    1093. Biotin deficiency stimulates survival pathways in hum an lymphoma cells exposed to antineoplastic drugs. (PubMed id 15681168)9 Griffin J.B. and Zempleni J. (2005)
    1094. Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-kappaB activation. (PubMed id 15684433)9 Zeyda M....Stulnig T.M. (2005)
    1095. CD40/CD154 ligation induces mononuclear cell adhesion to human renal proximal tubule cells via increased ICAM-1 expression. (PubMed id 15713910)9 Li H. and Nord E.P. (2005)
    1096. Effects of acetaldehyde and TNF alpha on the inhibitory kappa B-alpha protein and nuclear factor kappa B activation in hepatic stellate cells. (PubMed id 15550448)9 Novitskiy G....Mezey E. (2005)
    1097. Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation. (PubMed id 16343349)9 Ehrhart J....Shytle R.D. (2005)
    1098. Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis. (PubMed id 16909005)9 Kiaei M....Beal M.F. (2005)
    1099. c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells. (PubMed id 15890690)9 Gururajan M....Bondada S. (2005)
    1100. A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kappa B p65/p50 dimer. (PubMed id 16081828)9 Lesner A....Simm M. (2005)
    1101. CD40 ligand expression correlates with resolution of peritonitis and mononuclear cell recruitment. (PubMed id 15981772)9 Glik A....Douvdevani A. (2005)
    1102. Markers of inflammation and their clinical significance. (PubMed id 15823493)9 Ballantyne C.M. and Nambi V. (2005)
    1103. Transfection of human monocyte-derived dendritic cells with CpG oligonucleotides. (PubMed id 15877606)9 Erhardt M....Schmidt-Wolf I.G. (2005)
    1104. Stabilization of basally translated NF-kappaB-inducing kinase (NIK) protein functions as a molecular switch of processing of NF-kappaB2 p100. (PubMed id 16223731)9 Qing G....Xiao G. (2005)
    1105. Laboratory diagnosis of acute myocardial injury. (PubMed id 15914301)9 Melanson S.F. and Tanasijevic M.J. (2005)
    1106. Quantitative mRNA expression analysis of co-stimulatory molecules in sequential biopsies from heart allografts. (PubMed id 16162107)9 Akdere F....Mengel M. (2005)
    1107. CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 response. (PubMed id 15650062)9 Reid G.S....Schultz K.R. (2005)
    1108. Combined thrombolysis with abciximab favourably influences platelet-leukocyte interactions and platelet activation in acute myocardial infarction. (PubMed id 16261288)9 Szabo S....Hoffmeister H.M. (2005)
    1109. Critical role of host gammadelta T cells in experimental acute graft-versus-host disease. (PubMed id 15797996)9 Maeda Y....Ferrara J.L. (2005)
    1110. Mitogen induced activation, proliferation and surface antigen expression patterns in unmutated and hypermutated chronic lymphocytic leukemia cells. (PubMed id 15946308)9 Vilpo J....Rosenquist R. (2005)
    1111. Characterization and expression of a CD40 homolog gen e in Japanese flounder Paralichthys olivaceus. (PubMed id 16189669)9 Park C.I....Aoki T. (2005)
    1112. Inhibition of IkappaBalpha phosphorylation prevents glutamate-induced NF-kappaB activation and neuronal cell death. (PubMed id 15986728)9 Pizzi M....Spano P.F. (2005)
    1113. Dendritic cells pulsed with gp96-peptide complexes derived from human hepatocellular carcinoma (HCC) induce specific cytotoxic T lymphocytes. (PubMed id 15965645)9 Wang X.H....Xie Y. (2005)
    1114. Identification and characterization of circulating human transitional B cells. (PubMed id 15701725)9 Sims G.P....Lipsky P.E. (2005)
    1115. Defining the proinflammatory phenotype using high sensitive C-reactive protein levels as the biomarker. (PubMed id 15899961)9 Devaraj S....Jialal I. (2005)
    1116. Endothelin-1 induces CD40 but not IL-6 in human monocytes via the proinflammatory transcription factor NF-kappaB. (PubMed id 15946919)9 Browatzki M....Kranzhofer R. (2005)
    1117. De novo mutation causing X-linked hyper-IgM syndrome: a family study in Taiwan. (PubMed id 15997875)9 Ma Y.C....Wu J.Y. (2005)
    1118. Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells. (PubMed id 15784460)9 Taams L.S....Lafeber F.P. (2005)
    1119. C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. (PubMed id 16370373)9 Fournel S....Guichard G. (2005)
    1120. Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control: results from the pioneer study. (PubMed id 15963388)9 PfA1tzner A....Forst T. (2005)
    1121. Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. (PubMed id 15774573)9 Apple F.S....Jaffe A.S. (2005)
    1122. Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines. (PubMed id 16101141)9 Ramachandran C....Melnick S.J. (2005)
    1123. Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis. (PubMed id 15914559)9 Kater A.P....Kipps T.J. (2005)
    1124. Presence and maturity of dendritic cells in melanoma lymph node metastases. (PubMed id 15983979)9 Polak M.E....Cree I.A. (2005)
    1125. Human leukocyte antigen expression by peritoneal macrophages from women with pelvic endometriosis is depressed but coordinated with costimulatory molecule expression. (PubMed id 15831297)9 Kusume T....Fukaya T. (2005)
    1126. Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice. (PubMed id 15857890)9 Huang D....Ransohoff R.M. (2005)
    1127. Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS. (PubMed id 15953129)9 Norata G.D....Catapano A.L. (2005)
    1128. Cobrotoxin inhibits NF-kappa B activation and target gene expression through reaction with NF-kappa B signal molecules. (PubMed id 15938622)9 Park M.H....Hong J.T. (2005)
    1129. Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40. (PubMed id 15972685)9 BlA1ml S....Leitinger N. (2005)
    1130. Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival. (PubMed id 16099873)9 Pham L.V....Ford R.J. (2005)
    1131. Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. (PubMed id 16277667)9 Han S.S....Janz S. (2005)
    1132. Characterization of dendritic-like cells derived from t(9;22) acute lymphoblastic leukemia blasts. (PubMed id 15302850)9 Lee J....Wetzler M. (2004)
    1133. Dose-dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kappaB) in EA.hy.926 endothelial cells after low-dose X-irradiation. (PubMed id 15164793)9 Rodel F....Voll R.E. (2004)
    1134. Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation. (PubMed id 15585864)9 Ni C.Z....Ely K.R. (2004)
    1135. Lipoprotein lipase protects bovine endothelial cells from human NK cytotoxic activity. (PubMed id 15051515)9 De Sanctis J.B....Bianco N.E. (2004)
    1136. Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. (PubMed id 15131062)9 Zheng B....Younes A. (2004)
    1137. Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis. Tissue characteristics compared to primary atherosclerosis. (PubMed id 15528935)9 Skowasch D....Bauriedel G. (2004)
    1138. Small interference RNA modulation of IL-10 in human monocyte-derived dendritic cells enhances the Th1 response. (PubMed id 15162438)9 Liu G....Yu J.S. (2004)
    1139. Allogeneic reaction induces dendritic cell maturation through proinflammatory cytokine secretion. (PubMed id 14742992)9 Laurin D....Eljaafari A. (2004)
    1140. Paclitaxel treatment of breast cancer cell lines modulates Fas/Fas ligand expression and induces apoptosis which can be inhibited through the CD40 receptor. (PubMed id 15138361)9 Stumm S....GA1ckel B. (2004)
    1141. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. (PubMed id 15470505)9 Bonizzi G....Karin M. (2004)
    1142. Truncated thioredoxin: physiological functions and mechanism. (PubMed id 14713335)9 Pekkari K. and Holmgren A. (2004)
    1143. CD16+ human monocyte-derived dendritic cells matured with different and unrelated stimuli promote similar allogeneic Th2 responses: regulation by pro- and anti-inflammatory cytokines. (PubMed id 15277404)9 Rivas-Carvalho A....SA!nchez-Torres C. (2004)
    1144. Expression of transforming growth factor beta (TGF-beta1) in human epithelial alveolar cells: a pro-inflammatory mediator independent pathway. (PubMed id 15051419)9 Kwong K.Y....Minoo P. (2004)
    1145. Pharmacodynamics in the development of new immunosuppressive drugs. (PubMed id 15570181)9 Burkhart C....Welzenbach K. (2004)
    1146. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. (PubMed id 15485626)9 Ramakrishnan P....Wallach D. (2004)
    1147. [Acute coronary syndrome and inflammation. Biomarkers for diagnostics and risk stratification] (PubMed id 15599673)9 Trepels T....Fichtlscherer S. (2004)
    1148. [BAY11-7082 and Lactacystein in CD154-induced NF-kappaB activation] (PubMed id 15562757)9 Zhang X....Yu M.X. (2004)
    1149. Rapid regulation of platelet activation in vivo by nitric oxide. (PubMed id 15066953)9 SchAofer A....Channon K.M. (2004)
    1150. Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice. (PubMed id 15256474)9 Saha A....Bhattacharya-Chatterjee M. (2004)
    1151. Epstein-Barr virus promotes human monocyte survival and maturation through a paracrine induction of IFN-alpha. (PubMed id 15210790)9 Salek-Ardakani S....Arrand J.R. (2004)
    1152. [Hyper-IgM syndrome in members of two unrelated Chilean families: molecular and mutation analysis] (PubMed id 15631205)9 Luttges P.D....De Cornejo M.L. (2004)
    1153. Cross-linking of CD40 using anti-CD40 antibody, 5C11, has different effects on XG2 multiple myeloma cells. (PubMed id 15158611)9 Qi C.J....Zhang X.G. (2004)
    1154. Molecular study on chicken tumor necrosis factor receptor-II and tumor necrosis factor receptor-associated factor-5. (PubMed id 15127839)9 Abdalla S.A....Matsuda H. (2004)
    1155. Differential regulation of gene expression following CD40 activation of leukemic compared to healthy B cells. (PubMed id 15161673)9 Gricks C.S....Gribben J.G. (2004)
    1156. Chemotherapy plus G-CSF mobilized peripheral blood stem cell harvests from acute myeloid leukaemia patients contain large amounts of polyclonal myeloid linnegCD11cpos dendritic precursor cells. (PubMed id 14871251)9 Sanchez J....Alvarez M.A. (2004)
    1157. Programmed cell death of peripheral blood B cells determined by laser scanning cytometry in Sjogren's syndrome with a special emphasis on BAFF. (PubMed id 15622444)9 Szodoray P....Jonsson R. (2004)
    1158. CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway. (PubMed id 14687667)9 Mukundan L....Suttles J. (2004)
    1159. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways. (PubMed id 15059275)9 Hwang S.Y....Kim H.Y. (2004)
    1160. Comparison of morphological and functional characteristics of primary-cultured human conjunctival epithelium and of Wong-Kilbourne derivative of Chang conjunctival cell line. (PubMed id 14729358)9 De Saint Jean M....Brignole F. (2004)
    1161. Hyper-IgM syndrome: report of one case. (PubMed id 15868849)9 Ma Y.C....Lin S.C. (2004)
    1162. Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. (PubMed id 14978013)9 Dedeoglu F....Geha R.S. (2004)
    1163. The effect of LIGHT in inducing maturation of monocyte-derived dendritic cells from MDS patients. (PubMed id 15103504)9 Zou G.M....Klingemann H.G. (2004)
    1164. Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma. (PubMed id 15481028)9 Pallares J....Matias-Guiu X. (2004)
    1165. [Morphological characteristics and immunophenotype of dendritic cells generated from monocytes of human peripheral blood] (PubMed id 15359705)9 Khalturina E.O....KiselevskiA- M.V. (2004)
    1166. Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation. (PubMed id 15548703)9 Hammerman P.S....Thompson C.B. (2004)
    1167. OM-197-MP-AC adjuvant properties: the in vitro maturation of normal and leukemic dendritic cells in a serum-free culture model. (PubMed id 15481142)9 VAcran J....Olive D. (2004)
    1168. Bradykinin B2 receptor mediates NF-kappaB activation and cyclooxygenase-2 expression via the Ras/Raf-1/ERK pathway in human airway epithelial cells. (PubMed id 15470067)9 Chen B.C....Lin C.H. (2004)
    1169. Defective costimulatory function is a striking feature of antigen-presenting cells in an HLA-B27-transgenic rat model of spondylarthropathy. (PubMed id 15146433)9 Hacquard-Bouder C....Breban M. (2004)
    1170. Prognostic value of placental growth factor in patients with acute chest pain. (PubMed id 14747500)9 Heeschen C....Zeiher A.M. (2004)
    1171. C-reactive protein-induced expression of CD40-CD40L and the effect of lovastatin and fenofibrate on it in human vascular endothelial cells. (PubMed id 15467191)9 Lin R....Yang G. (2004)
    1172. CD40 and vascular inflammation. (PubMed id 15197419)9 Urbich C. and Dimmeler S. (2004)
    1173. Immunopathogenesis of acute graft-versus-host disease: implications for novel preventive and therapeutic strategies. (PubMed id 15449032)9 Zeiser R....Finke J. (2004)
    1174. Ebola and Marburg virus-like particles activate human myeloid dendritic cells. (PubMed id 15302213)9 Bosio C.M....Bavari S. (2004)
    1175. [Nonlipid effects of fibrates] (PubMed id 15230150)9 CeliA8ska-LAPwenhoff M. and Undas A. (2004)
    1176. All-trans-retinoic acid induces interleukin-8 via the nuclear factor-kappaB and p38 mitogen-activated protein kinase pathways in normal human keratinocytes. (PubMed id 15610518)9 Dai X....Hashimoto K. (2004)
    1177. Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers. (PubMed id 15078798)9 Harding S.A....Newby D.E. (2004)
    1178. RT-PCR analysis of RNA extracted from Bouin-fixed and paraffin-embedded lymphoid tissues. (PubMed id 15507667)9 Gloghini A....Carbone A. (2004)
    1179. Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas. (PubMed id 15004148)9 Thornton M.V....Finke J.H. (2004)
    1180. Infiltrating cells, related cytokines and chemokine receptors in lesional skin of patients with dermatomyositis. (PubMed id 15491417)9 Caproni M....Fabbri P. (2004)
    1181. The interaction of human dendritic cells with yeast and germ-tube forms of Candida albicans leads to efficient fungal processing, dendritic cell maturation, and acquisition of a Th1 response-promoting function. (PubMed id 14525965)9 Romagnoli G....Torosantucci A. (2004)
    1182. CD40/CD40 homodimers are required for CD40-induced phosphatidylinositol 3-kinase-dependent expression of B7.2 by human B lymphocytes. (PubMed id 14676197)9 Reyes-Moreno C....Mourad W. (2004)
    1183. Identification of genes expressed in malignant cells that promote invasion. (PubMed id 14695211)9 Walter-Yohrling J....Teicher B.A. (2003)
    1184. Three novel mutations reflect the variety of defects causing phenotypically diverse X-linked hyper-IgM syndrome. (PubMed id 12823286)9 LA^pez-Granados E....GarcA-a-RodrA-guez M.C. (2003)
    1185. High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism. (PubMed id 12419773)9 Kang B.P....Meggs L.G. (2003)
    1186. Insulin-like growth factor I promotes maturation and inhibits apoptosis of immature cord blood monocyte-derived dendritic cells through MEK and PI 3-kinase pathways. (PubMed id 12930919)9 Liu E....Lau Y.L. (2003)
    1187. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. (PubMed id 12865416)9 Avery D.T....Tangye S.G. (2003)
    1188. Differential gene expression of cytokine and cell surface molecules in T cell subpopulation derived from mammary gland secretion of cows. (PubMed id 14750552)9 Asai K....Kumagai K. (2003)
    1189. S epsilon S mu and S epsilon S gamma switch circles in human nasal mucosa following ex vivo allergen challenge: evidence for direct as well as sequential class switch recombination. (PubMed id 14500683)9 Cameron L....Hamid Q. (2003)
    1190. Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. (PubMed id 14499877)9 Mulhaupt F....Mach F. (2003)
    1191. Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis. (PubMed id 14610488)9 Lee W.I....Ochs H.D. (2003)
    1192. Inhibition of NF-kappaB sensitizes A431 cells to epidermal growth factor-induced apoptosis, whereas its activation by ectopic expression of RelA confers resistance. (PubMed id 12714587)9 Anto R.J....Karunagaran D. (2003)
    1193. Coordinated regulation of the promoter and enhancer regions of human CD23 gene by signal through IL-4R and CD40, and the role of Ku70/80 in the enhancer activity. (PubMed id 12968637)9 Imai M....Morio T. (2003)
    1194. Activation of human dendritic cells is modulated by components of the outer membranes of Neisseria meningitidis. (PubMed id 14500478)9 Al-Bader T....Friedmann P.S. (2003)
    1195. CD40 ligand is a critical effector of Epstein-Barr virus in host cell survival and transformation. (PubMed id 12805559)9 Imadome K....Yamanashi Y. (2003)
    1196. Stretch-induced IL-6 secretion from endothelial cells requires NF-kappaB activation. (PubMed id 12901869)9 Kobayashi S....Sokabe M. (2003)
    1197. Tumor cells engineered with IL-12 and IL-15 genes induce protective antibody responses in nude mice. (PubMed id 12847220)9 Orengo A.M....Ferrini S. (2003)
    1198. Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors. (PubMed id 12897145)9 Romieu-Mourez R....Sonenshein G.E. (2003)
    1199. Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells. (PubMed id 12881706)9 Ling M.T....Wong Y.C. (2003)
    1200. Increased CD40 expression in skin fibroblasts from patients with systemic sclerosis (SSc): role of CD40-CD154 in the phenotype of SSc fibroblasts. (PubMed id 14515263)9 Fukasawa C....Kamatani N. (2003)
    1201. Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease-substrate interaction. (PubMed id 12704411)9 Johnson K.J....Galanis E. (2003)
    1202. Neither acute rejection nor immunosuppressant drug therapy (cyclosporine or tacrolimus) correlates with expression of either CD40 or CD154 on peripheral blood cells among human cardiac transplant patients. (PubMed id 12962873)9 Domenech N....Castro-Beiras A. (2003)
    1203. Rapamycin impairs antigen uptake of human dendritic cells. (PubMed id 12544886)9 Monti P....Piemonti L. (2003)
    1204. Dendritic cells generated in the presence of granulocyte-macrophage colony-stimulating factor and IFN-alpha are potent inducers of HIV-specific CD8 T cells. (PubMed id 12891059)9 Carbonneil C....Weiss L. (2003)
    1205. CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP. (PubMed id 12626566)9 Baccam M....Bishop G.A. (2003)
    1206. Autoimmune thyroid disease: propagation and progressi on. (PubMed id 12534350)9 Weetman A.P. (2003)
    1207. TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients. (PubMed id 12684428)9 Schlienger K....June C.H. (2003)
    1208. Alteration in the production of IL-10 and IL-12 and aberrant expression of CD23, CD83 and CD86 by monocytes or monocyte-derived dendritic cells from atopic dermatitis patients. (PubMed id 12631251)9 Aiba S....Tagami H. (2003)
    1209. Pooled human gammaglobulin modulates surface molecule expression and induces apoptosis in human B cells. (PubMed id 12603211)9 Toyoda M....Jordan S.C. (2003)
    1210. iC3b arrests monocytic cell differentiation into CD1c-expressing dendritic cell precursors: a mechanism for transiently decreased dendritic cells in vivo after human skin injury by ultraviolet B. (PubMed id 12713585)9 Takahara M....Cooper K.D. (2003)
    1211. NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells. (PubMed id 12934082)9 Hermisson M. and Weller M. (2003)
    1212. Clinical-scale generation of dendritic cells in a closed system. (PubMed id 12843800)9 Sorg R.V....Wernet P. (2003)
    1213. The immunomodulatory role of human conjunctival epithelial cells. (PubMed id 12939308)9 Zhan H....Calder V.L. (2003)
    1214. Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability. (PubMed id 12871932)9 Demarchi F.... Schneider C. (2003)
    1215. Monocyte response to Th1 stimulation and effector function toward human mesangial cells are not impaired in patients with lupus nephritis. (PubMed id 12584053)9 Kuroiwa T....Boumpas D.T. (2003)
    1216. Monocyte-derived IL12, CD86 (B7-2) and CD40L expression in relapsing and progressive multiple sclerosis. (PubMed id 12672403)9 Filion L.G....Freedman M.S. (2003)
    1217. Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. (PubMed id 12857898)9 Dudziak D....Bornkamm G.W. (2003)
    1218. A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation. (PubMed id 12517949)9 Sedlik C....Amigorena S. (2003)
    1219. Human CD34(+) blood cells induce T-cell unresponsiveness to specific alloantigens only under costimulatory blockade. (PubMed id 12543104)9 Arpinati M....Rondelli D. (2003)
    1220. Immunomodulation during sublingual therapy in allergic children. (PubMed id 12787302)9 Ippoliti F....Frediani T. (2003)
    1221. Lovastatin inhibits bone marrow-derived dendritic cel l maturation and upregulates proinflammatory cytokine production. (PubMed id 12914758)9 Sun D. and Fernandes G. (2003)
    1222. Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation. (PubMed id 12471036)9 Deng W.G....Wu K.K. (2003)
    1223. Inducible CD40 expression mediates NFkappaB activation and cytokine secretion in human colonic fibroblasts. (PubMed id 12970138)9 Gelbmann C.M....Rogler G. (2003)
    1224. A novel interaction between protein kinase D and TNF receptor-associated factor molecules regulates B cell receptor-CD40 synergy. (PubMed id 14568940)9 Haxhinasto S.A. and Bishop G.A. (2003)
    1225. A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas. (PubMed id 11825564)9 Pham L.V....Ford R.J. (2002)
    1226. NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta. (PubMed id 11754354)9 Kronfeld I....Brodie C. (2002)
    1227. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. (PubMed id 12154359)9 Litinskiy M.B....Cerutti A. (2002)
    1228. Cellular responses to murine CD40 in a mouse B cell line may be TRAF dependent or independent. (PubMed id 11754002)9 Manning E....Noelle R.J. (2002)
    1229. 3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells. (PubMed id 12426205)9 Wagner A.H....Hecker M. (2002)
    1230. [The mechanism of HIV replication at the site of inflammation coinfected with HIV and M. tuberculosis] (PubMed id 12440144)9 Nakata K....Fujita A. (2002)
    1231. Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling. (PubMed id 12370254)9 Arron J.R....Choi Y. (2002)
    1232. Adhesion of B cell lines to endothelial cells from human lymphoid tissue modulates tyrosine phosphorylation and endothelial cell activation. (PubMed id 12421971)9 Reyes L.I....Rosemblatt M. (2002)
    1233. B-cell activation and allosensitization after left ventricular assist device implantation is due to T-cell activation and CD40 ligand expression. (PubMed id 11872239)9 Schuster M....Itescu S. (2002)
    1234. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. (PubMed id 12402041)9 Tan J....Mullan M.J. (2002)
    1235. Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation. (PubMed id 11796708)9 Gao G....Sandy J.D. (2002)
    1236. Unimpaired activation of c-Jun NH2-terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patients with X-linked agammaglobulinemia. (PubMed id 12148599)9 Brunner C....Schuster V. (2002)
    1237. X-linked hyper-IgM syndrome associated with Cryptosporidium parvum and Cryptococcus neoformans infections: the first case with molecular diagnosis in Korea. (PubMed id 11850600)9 Jo E.K....Kook H. (2002)
    1238. Depletion of intracellular GTP results in nuclear factor-kappaB activation and intercellular adhesion molecule-1 expression in human endothelial cells. (PubMed id 12181421)9 Weigel G....Wolner E. (2002)
    1239. IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production. (PubMed id 12193748)9 McDyer J.F....Ragheb J.A. (2002)
    1240. CD40 ligand inhibits endothelial cell migration by in creasing production of endothelial reactive oxygen species. (PubMed id 12186804)9 Urbich C....Dimmeler S. (2002)
    1241. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleuki n (IL)-4 and IL-12. (PubMed id 12208883)9 Lee B.O....Randall T.D. (2002)
    1242. Ceramide and cell death receptor clustering. (PubMed id 12531547)9 Gulbins E. and Grassme H. (2002)
    1243. Suppression of IL-12 production by soluble CD40 ligand: evidence for involvement of the p44/42 mitogen-activated protein kinase pathway. (PubMed id 11937531)9 Wittmann M....Werfel T. (2002)
    1244. Cooperation between secretory phospholipase A2 and TNF-receptor superfamily signaling: implications for the inflammatory response in atherogenesis. (PubMed id 12386144)9 Fuentes L....Nieto M.L. (2002)
    1245. Cross-talk between CD40 and CD40L: lessons from prima ry immune deficiencies. (PubMed id 14752331)9 Ferrari S. and Plebani A. (2002)
    1246. New cytokine delivery system using gelatin microspheres containing interleukin-10 for experimental inflammatory bowel disease. (PubMed id 11907157)9 Nakase H....Chiba T. (2002)
    1247. Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors. (PubMed id 12060665)9 Mukhopadhyay A....Aggarwal B.B. (2002)
    1248. Temporal sequence and functional implications of V beta-specific T cell receptor down-regulation and costimulatory molecule expression following in vitro stimulation with the staphylococcal superantigen Toxic shock syndrome toxin-1. (PubMed id 11865410)9 Kum W.W....Chow A.W. (2002)
    1249. The pathogenesis of oral lichen planus. (PubMed id 12191961)9 Sugerman P.B....Bigby M. (2002)
    1250. Cytokine control of memory B cell homing machinery. (PubMed id 12165486)9 Roy M.P....Butcher E.C. (2002)
    1251. Inhibition of microglial CD40 expression by pituitary adenylate cyclase-activating polypeptide is mediated by interleukin-10. (PubMed id 12020953)9 Kim W.K....Jonakait G.M. (2002)
    1252. Natural type I interferon-producing cells as a link between innate and adaptive immunity. (PubMed id 12480256)9 Kadowaki N. and Liu Y.J. (2002)
    1253. Expression of CD40, CD44, bcl-2 antigens and rate of cell proliferation on fine needle aspirates from metastatic melanoma. (PubMed id 11985564)9 Sviatoha V....Skoog L. (2002)
    1254. Distinctive response of thyroid-infiltrating mononuclear cells to B cell activation through CD40 and interleukin-4 in Graves' patients. (PubMed id 12242076)9 Itoh M....Hagino Y. (2002)
    1255. Differential regulation of maturation and apoptosis of human monocyte-derived dendritic cells mediated by MHC class II. (PubMed id 12202400)9 Lokshin A.E....Gorelik E. (2002)
    1256. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. (PubMed id 11877450)9 Lee J.H....Lee J.J. (2002)
    1257. Bi-directional modulation of T cell-dependent antibody production by prostaglandin E(2). (PubMed id 11751754)9 He X....Stuart J.M. (2002)
    1258. Peroxisome proliferator-activated receptor gamma-mediated NF-kappa B activation and apoptosis in pre-B cells. (PubMed id 12471115)9 Schlezinger J.J....Sherr D.H. (2002)
    1259. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. (PubMed id 12460867)9 SchAPnbeck U....Libby P. (2002)
    1260. Life and death within germinal centres: a double-edged sword. (PubMed id 12383195)9 Guzman-Rojas L....Martinez-Valdez H. (2002)
    1261. CD95 (Fas) expression is regulated by sequestration in the Golgi complex in B-cell lymphoma. (PubMed id 12139737)9 Haynes A.P....Thomson B.J. (2002)
    1262. Butyrate affects differentiation, maturation and func tion of human monocyte-derived dendritic cells and macrophages. (PubMed id 12390312)9 Millard A.L....Bernard J. (2002)
    1263. Regulation of the gadd45beta promoter by NF-kappaB. (PubMed id 12162804)9 Jin R....Franzoso G. (2002)
    1264. Targeting T cell costimulation in autoimmune disease. (PubMed id 12223069)9 Stuart R.W. and Racke M.K. (2002)
    1265. The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis. (PubMed id 12237284)9 Bugajska U....Trejdosiewicz L.K. (2002)
    1266. 2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-alpha and anti-CD40-induced activation of NF-kappaB/Rel in dendritic cells: p50 homodimer activation is not affected. (PubMed id 12181450)9 Ruby C.E....Kerkvliet N.I. (2002)
    1267. Hyaluronic acid and chondroitin sulphate A rapidly promote differentiation of immature DC with upregulation of costimulatory and antigen-presenting molecules, and enhancement of NF-kappaB and protein kinase activity. (PubMed id 11841687)9 Yang R....Kiessling R. (2002)
    1268. CD40 employs p38 MAP kinase in IgE isotype switching. (PubMed id 11708812)9 Brady K....Moynagh P.N. (2001)
    1269. Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers. (PubMed id 11468143)9 Szmania S....van Rhee F. (2001)
    1270. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. (PubMed id 11241286)9 Vulcano M.... Sozzani S. (2001)
    1271. Expression of costimulatory molecules on peripheral blood lymphocytes of patients with systemic lupus erythematosus. (PubMed id 11302879)9 Bijl M....Kallenberg C.G. (2001)
    1272. Normal human lung fibroblasts differently modulate interleukin-10 and interleukin-12 production by monocytes: implications for an altered immune response in pulmonary chronic inflammation. (PubMed id 11713101)9 Vancheri C....Crimi N. (2001)
    1273. 1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes. (PubMed id 11517017)9 Canning M.O....Drexhage H.A. (2001)
    1274. Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. (PubMed id 11313274)9 Hinz M....Scheidereit C. (2001)
    1275. Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. (PubMed id 11390609)9 Sundstrom J.B....Rollin P.E. (2001)
    1276. A modified ex vivo skin organ culture system for functional studies. (PubMed id 11380151)9 Companjen A.R....Prens E.P. (2001)
    1277. Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. (PubMed id 11312255)9 Yoshimura S....Feldmann M. (2001)
    1278. Enhancement of antigen-presenting ability of B lymphoma cells by immunostimulatory CpG-oligonucleotides and anti-CD40 antibody. (PubMed id 11348665)9 Chen W....Cao X. (2001)
    1279. Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A. (PubMed id 11133852)9 Brignole F....Baudouin C. (2001)
    1280. Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor, and CD40. (PubMed id 11278268)9 Luftig M.A....Kieff E. (2001)
    1281. Expression of HLA-DR, CAM and co-stimulatory molecules on cord blood monocytes. (PubMed id 11168518)9 Varis I....Brichard B. (2001)
    1282. CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. (PubMed id 11359840)9 Schwabe R.F....Brenner D.A. (2001)
    1283. CD40L induces matrix-metalloproteinase-9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation. (PubMed id 11426939)9 Smola-Hess S....Pfister H. (2001)
    1284. Loss of memory (CD27) B lymphocytes in HIV-1 infectio n. (PubMed id 11399977)9 De Milito A....Chiodi F. (2001)
    1285. Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium. (PubMed id 11256945)9 Haddad J.J....Land S.C. (2001)
    1286. Multiple sclerosis: deficient in vitro responses of blood mononuclear cells to IFN-beta. (PubMed id 11696016)9 Huang Y.M....Link H. (2001)
    1287. Activation of beta(2)-adrenoceptor prevents shiga toxin 2-induced TNF-alpha gene transcription. (PubMed id 11675405)9 Nakamura A....Kohsaka T. (2001)
    1288. Immunologic reconstitution following bone marrow transplantation for X-linked hyper IgM syndrome. (PubMed id 11237554)9 Duplantier J.E....Good R.A. (2001)
    1289. The role of NF-kappaB as a survival factor in environ mental chemical-induced pre-B cell apoptosis. (PubMed id 11160867)9 Mann K.K....Quadri S. (2001)
    1290. Functional properties of lymphocytes in idiopathic thrombocytopenic purpura. (PubMed id 11756003)9 Webber N.P....Schattner E.J. (2001)
    1291. Apoptosis induced by the antigen receptor and Fas in a variant of the immature B cell line WEHI-231 and in splenic immature B cells. (PubMed id 11282997)9 Tian M.T....DeFranco A.L. (2001)
    1292. NF-kappaB is involved in the survival of cerebellar granule neurons: association of IkappaBbeta [correction of Ikappabeta] phosphorylation with cell survival. (PubMed id 11181838)9 Koulich E....D'mello S. (2001)
    1293. Pathways for self-tolerance and the treatment of autoimmune diseases. (PubMed id 11445125)9 Goodnow C.C. (2001)
    1294. Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression. (PubMed id 11514596)9 Landmann S....Reith W. (2001)
    1295. Regulation of CD40 ligand expression in systemic lupus erythematosus. (PubMed id 11604589)9 Crow M.K. and Kirou K.A. (2001)
    1296. Characterization of cytokine, growth factor receptor, costimulatory and adhesion molecule expression patterns of bone marrow blasts in relapsed childhood B cell precursor all. (PubMed id 11145841)9 Kebelmann-Betzing C....Seeger K. (2001)
    1297. CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. (PubMed id 11313386)9 Shlapatska L.M.... Sidorenko S.P. (2001)
    1298. Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506). (PubMed id 11174203)9 Panhans-Gross A....Bieber T. (2001)
    1299. Autologous antileukemic immune response induced by ch ronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes. (PubMed id 11426465)9 Takahashi S....Brenner M.K. (2001)
    1300. Expression of adhesion and activation molecules in human buccal epithelial cell lines and normal human buccal epithelium in situ. (PubMed id 11168856)9 Farmer I....Fortune F. (2001)
    1301. Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors. (PubMed id 11123319)9 Shen C.H. and Stavnezer J. (2001)
    1302. A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation. (PubMed id 11406619)9 Arron J.R....Choi Y. (2001)
    1303. Mechanisms of CD23 hyperexpression on B cells from patients with rheumatoid arthritis. (PubMed id 11409113)9 De Miguel S....Fernandez-Gutierrez B. (2001)
    1304. CD40 signaling and Alzheimer's disease pathogenesis. (PubMed id 11578772)9 Town T....Mullan M. (2001)
    1305. Morphological interactions of interdigitating dendritic cells with B and T cells in human mesenteric lymph nodes. (PubMed id 11438461)9 Takahashi K....Tadaatsu A. (2001)
    1306. Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching. (PubMed id 11160161)9 Jabara H.H....Geha R.S. (2001)
    1307. CD40 expression and function on human dermal microvascular endothelial cells: role in cutaneous inflammation. (PubMed id 11488834)9 Singh S.R....Swerlick R.A. (2001)
    1308. The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs. (PubMed id 11328385)9 Skibinski G....James K. (2001)
    1309. Human thymus contains 2 distinct dendritic cell populations. (PubMed id 11238115)9 Vandenabeele S....Shortman K. (2001)
    1310. CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines. (PubMed id 11754818)9 Wang Y....Lehner T. (2001)
    1311. The biphasic immunoregulation of pyrimidylpiperazine (Y-40138) is IL-10 sensitive and requires NF-kappa B targeting in the alveolar epithelium. (PubMed id 11325794)9 Haddad J.J....Land S.C. (2001)
    1312. Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. (PubMed id 11313271)9 Granziero L....Caligaris-Cappio F. (2001)
    1313. Monocytes in multiple sclerosis: phenotype and cytokine profile. (PubMed id 11108949)9 Kouwenhoven M....Link H. (2001)
    1314. Transcript profiling of human dendritic cells maturation-induced under defined culture conditions: comparison of the effects of tumour necrosis factor alpha, soluble CD40 ligand trimer and interferon gamma. (PubMed id 11529869)9 Moschella F....Harris P.E. (2001)
    1315. Essential role of human leukocyte antigen-encoded proteasome subunits in NF-kappaB activation and prevention of tumor necrosis factor-alpha-induced apoptosis. (PubMed id 10671572)9 Hayashi T. and Faustman D. (2000)
    1316. Membrane and transmembrane signaling in Herpesvirus saimiri-transformed human CD4(+) and CD8(+) T lymphocytes is ATM-independent. (PubMed id 10837420)9 Rivero-Carmena M....Regueiro J.R. (2000)
    1317. The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells. (PubMed id 10940869)9 Woltman A.M....van Kooten C. (2000)
    1318. A flow cytometric immune function assay for human peripheral blood dendritic cells. (PubMed id 10770287)9 Willmann K. and Dunne J.F. (2000)
    1319. CD40-ligand stimulates myelopoiesis by regulating flt3-ligand and thrombopoietin production in bone marrow stromal cells. (PubMed id 10845907)9 Solanilla A....Ripoche J. (2000)
    1320. A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis. (PubMed id 11007952)9 Beyaert R....Van Huffel S. (2000)
    1321. Role for CD40-CD40 ligand interactions in the immune response to solid tumours. (PubMed id 11163401)9 Alexandroff A.B....Taub D.D. (2000)
    1322. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. (PubMed id 11015437)9 Do R.K....Chen-Kiang S. (2000)
    1323. CD154 stimulation of interleukin-12 synthesis in human endothelial cells. (PubMed id 11069068)9 LienenlA1ke B....Hecker M. (2000)
    1324. The structure of the nuclear factor-kappaB protein-DNA complex varies with DNA-binding site sequence. (PubMed id 10713070)9 Menetski J.P. (2000)
    1325. CD40 ligand, Bcl-2, and Bcl-xL spare group I Burkitt lymphoma cells from CD77-directed killing via Verotoxin-1 B chain but fail to p rotect against the holotoxin. (PubMed id 11042673)9 Gordon J....Lord J.M. (2000)
    1326. Cytomegalovirus infection of vascular cells induces expression of pro-inflammatory adhesion molecules by paracrine action of secreted interleukin-1beta. (PubMed id 10762222)9 Dengler T.J....SchAPnrich G. (2000)
    1327. Abundant expression of CD40 and CD40-ligand (CD154) in paediatric Langerhans cell histiocytosis lesions. (PubMed id 11044648)9 Egeler R.M....Claassen E. (2000)
    1328. The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. (PubMed id 10734024)9 Inan M.S....Giardina C. (2000)
    1329. Cytokine upregulation of the antigen presenting function of acute myeloid leukemia cells. (PubMed id 10720135)9 Boyer M.W....Yeager A.M. (2000)
    1330. [In vitro studies on dendritic cell derived from cord blood and its role in antitumor immunity] (PubMed id 11776177)9 Liu Y....Zhang H. (2000)
    1331. Tumor-induced dysfunction in interleukin-2 production and interleukin-2 receptor signaling: a mechanism of immune escape. (PubMed id 10685665)9 Rayman P....Finke J.H. (2000)
    1332. Characterization of dendritic cell differentiation pathways from cord blood CD34(+)CD7(+)CD45RA(+) hematopoietic progenitor cells. (PubMed id 11090056)9 Canque B....Gluckman J.C. (2000)
    1333. Consequences of Fas-mediated human dendritic cell apoptosis induced by measles virus. (PubMed id 10756053)9 Servet-Delprat C....Rabourdin-Combe C. (2000)
    1334. Induction and regulation of matrix metalloproteinase-12 by cytokines and CD40 signaling in monocyte/macrophages. (PubMed id 10720497)9 Wu L....Watanabe T. (2000)
    1335. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. (PubMed id 10875917)9 Chan F.K....Lenardo M.J. (2000)
    1336. Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors. (PubMed id 10725460)9 Holler N....Schneider P. (2000)
    1337. Expression of the costimulator molecules, CD40 and CD154, on lymphocytes from neonates and young children. (PubMed id 10715515)9 Elliott S.R....Macardle P.J. (2000)
    1338. CD40 ligation induces tissue factor expression in human vascular smooth muscle cells. (PubMed id 10623647)9 SchAPnbeck U....Libby P. (2000)
    1339. Molecular mechanisms of IgE regulation. (PubMed id 10669540)9 Bacharier L.B. and Geha R.S. (2000)
    1340. CD40 signaling in human dendritic cells is initiated within membrane rafts. (PubMed id 10880443)9 Vidalain P.O....ManiAc S. (2000)
    1341. Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis. (PubMed id 10995749)9 Patil S....Howe P.H. (2000)
    1342. Role and expression of CD40 on human retinal pigment epithelial cells. (PubMed id 11006243)9 Willermain F....Bruyns C. (2000)
    1343. Toremifene increases the expression of intercellular adhesion molecule-1 (ICAM-1) on MCF-7 breast cancer cells and Jurkat cells. (PubMed id 10632979)9 Komi J. and Lassila O. (2000)
    1344. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. (PubMed id 11043772)9 Rothstein T.L....Schneider T.J. (2000)
    1345. Role of tolerogen conformation in induction of oral tolerance in experimental autoimmune myasthenia gravis. (PubMed id 11034361)9 Im S.H....Fuchs S. (2000)
    1346. CD27/CD70 interactions regulate T dependent B cell differentiation. (PubMed id 10803880)9 Jacquot S. (2000)
    1347. Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype. (PubMed id 10799873)9 Dengler T.J. and Pober J.S. (2000)
    1348. Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. (PubMed id 10861097)9 Pulendran B....Palucka K. (2000)
    1349. Hodgkin disease: pharmacologic intervention of the CD40-NF kappa B pathway by a protease inhibitor. (PubMed id 11023520)9 Annunziata C.M....Cossman J. (2000)
    1350. In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells. (PubMed id 10733505)9 Chapoval A.I....Chen L. (2000)
    1351. Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells. (PubMed id 10878352)9 Cerutti A....Casali P. (2000)
    1352. A role for CD40-CD40 ligand interactions in the generation of type 1 cytokine responses in human leprosy. (PubMed id 10903757)9 Yamauchi P.S....Modlin R.L. (2000)
    1353. Elevated CTLA-4 expression on CD4 T cells from periodontitis patients stimulated with Porphyromonas gingivalis outer membrane antigen. (PubMed id 10632663)9 Aoyagi T....Hara K. (2000)
    1354. MIP-T3, a novel protein linking tumor necrosis factor receptor- associated factor 3 to the microtubule network. (PubMed id 10791955)9 Ling L. and Goeddel D.V. (2000)
    1355. Platelets and cytokines in concert with endothelial activation in patients with peripheral arterial occlusive disease. (PubMed id 10759010)9 Tsakiris D.A....Marbet G.A. (2000)
    1356. Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. (PubMed id 10974034)9 Abrams J.R....Krueger J.G. (2000)
    1357. Gammadelta T cells in BehAset's disease (BD) and recurrent aphthous stomatitis (RAS). (PubMed id 10594567)9 Freysdottir J....Fortune F. (1999)
    1358. Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells. (PubMed id 10092774)9 KaliA8ski P....Kapsenberg M.L. (1999)
    1359. Apotosis of mature B cells. (PubMed id 10626248)9 Tsubata T. (1999)
    1360. The dynamics of life and death of malignant lymphocytes. (PubMed id 10505772)9 Younes A. (1999)
    1361. Leucocyte recruitment in rupture prone regions of lipid-rich plaques: a prominent role for neovascularization? (PubMed id 10341843)9 de Boer O.J....Becker A.E. (1999)
    1362. Dopamine stimulates expression of the human immunodeficiency virus type 1 via NF-kappaB in cells of the immune system. (PubMed id 10454636)9 Rohr O....Schaeffer E. (1999)
    1363. In vivo description of dendritic cells in human renal cell carcinoma. (PubMed id 10411089)9 Schwaab T....Ernstoff M.S. (1999)
    1364. Respective involvement of TGF-beta and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors. (PubMed id 10577510)9 Caux C....Saeland S. (1999)
    1365. FADD expression and caspase activation in B-cell lymphomas resistant to Fas-mediated apoptosis. (PubMed id 10468853)9 Xerri L....Birg F. (1999)
    1366. Lymphocyte activation gene-3, a MHC class II ligand expressed on activated T cells, stimulates TNF-alpha and IL-12 production by monocytes and dendritic cells. (PubMed id 10072520)9 Avice M.N....Demeure C.E. (1999)
    1367. CD40-mediated activation of Ig-Cgamma1- and Ig-cepsilon germ-line promoters involves multiple TRAF family proteins. (PubMed id 10601998)9 Leo E....Reed J.C. (1999)
    1368. Biologically relevant phenotypic changes and enhanced growth properties induced in B lymphocytes by an EBV strain derived from a histologically aggressive Hodgkin's disease. (PubMed id 9935206)9 Dolcetti R....Boiocchi M. (1999)
    1369. Glucocorticoids increase the endocytic activity of human dendritic cells. (PubMed id 10464173)9 Piemonti L....Di Carlo V. (1999)
    1370. Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4. (PubMed id 10601358)9 Gupta S....Pernis A.B. (1999)
    1371. HepG2 human hepatoma cells express multiple cytokine genes. (PubMed id 10089137)9 StonA8ns I....Reinhart K. (1999)
    1372. Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10. (PubMed id 10586056)9 Tan J....Mullan M. (1999)
    1373. CD40 upregulation is independent of HHV-8 in the pathogenesis of Kaposi's sarcoma. (PubMed id 10439837)9 Kennedy M.M....O'Leary J.J. (1999)
    1374. Involvement of NF-kappaB p50/p65 heterodimer in activation of the human pro-interleukin-1beta gene at two subregions of the upstream enhancer element. (PubMed id 10080875)9 Goto M....Tanaka I. (1999)
    1375. The Fanconi anemia group C gene product modulates apoptotic responses to tumor necrosis factor-alpha and Fas ligand but does not suppress expression of receptors of the tumor necrosis factor receptor superfamily. (PubMed id 9923438)9 Koh P.S....Bagby G.C. (1999)
    1376. The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes. (PubMed id 10072495)9 Busch L.K. and Bishop G.A. (1999)
    1377. Experimental autoimmune encephalomyelitis in NF-kappa B-deficient mice:roles of NF-kappa B in the activation and differentiation of autoreactive T cells. (PubMed id 10453042)9 Hilliard B....Chen Y. (1999)
    1378. Phenotypically activated gammadelta T lymphocytes in the peripheral blood of patients with tuberculosis. (PubMed id 10353872)9 Behr-Perst S.I....Kaufmann S.H. (1999)
    1379. IgE hyperproduction through enhanced tyrosine phosphorylation of Janus kinase 3 in NC/Nga mice, a model for human atopic dermatitis. (PubMed id 9916733)9 Matsumoto M....Matsuda H. (1999)
    1380. Modulation of costimulatory molecules on follicular lymphoma cells by TNF and CD40. (PubMed id 10221513)9 Renard N....Salles G. (1999)
    1381. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. (PubMed id 10359116)9 Sallusto F....Lanzavecchia A. (1999)
    1382. Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells. (PubMed id 10525042)9 Mach F....Luster A.D. (1999)
    1383. Phenotypic and functional properties of dendritic cells isolated from human peripheral blood in comparison with mononuclear cells and T cells. (PubMed id 10075022)9 Huang Y.M....Link H. (1999)
    1384. Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand. (PubMed id 10216096)9 Hirano A....Murphy W.J. (1999)
    1385. Involvement of the CD27-CD70 co-stimulatory pathway in allogeneic T-cell response to follicular lymphoma cells. (PubMed id 10444164)9 Schmitter D....Pichert G. (1999)
    1386. Defects of T-cell effector function and post-thymic maturation in X-linked hyper-IgM syndrome. (PubMed id 10207167)9 Jain A....Strober W. (1999)
    1387. Induced expression of B7-1 on myeloma cells following retroviral gene transfer results in tumor-specific recognition by cytotoxic T cells. (PubMed id 10384156)9 Tarte K....Klein B. (1999)
    1388. Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells. (PubMed id 10570261)9 Aicher A....Clark E.A. (1999)
    1389. CD40 ligand-CD40 interaction induces chemokines in cervical carcinoma cells in synergism with IFN-gamma. (PubMed id 10201939)9 Altenburg A....Hess S. (1999)
    1390. Responsiveness of peripheral blood B cells to recombinant CD40 ligand in patients with systemic lupus erythematosus. (PubMed id 10342716)9 Harigai M....Kashiwazaki S. (1999)
    1391. Recombinant human CD40 ligand inhibits simian immunodeficiency virus replication: a role for interleukin- 16. (PubMed id 10593485)9 Lee M.E....Hillyer C.D. (1999)
    1392. Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins. (PubMed id 10462383)9 Elsharkawy A.M....Mann D.A. (1999)
    1393. Rapid induction of CD40 on a subset of granulocyte colony-stimulating factor-mobilized CD34(+) blood cells identifies myeloid committed progenitors and permits selection of nonimmunogenic CD40(-) progenitor cells. (PubMed id 10498601)9 Rondelli D....Tura S. (1999)
    1394. Mechanism of immunosuppression of the antirheumatic herb TWHf in human T cells. (PubMed id 9918235)9 Ho L.J....Lai J.H. (1999)
    1395. Differential regulation of rheumatoid synovial cell interleukin-12 production by tumor necrosis factor alpha and CD40 signals. (PubMed id 10513808)9 Kitagawa M....Sumida T. (1999)
    1396. CD40 expression in bladder cancer. (PubMed id 10398138)9 Cooke P.W....Young L.S. (1999)
    1397. Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses. (PubMed id 9874559)9 Schultze J.L....Nadler L.M. (1999)
    1398. Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. (PubMed id 10520003)9 Kitada S....Reed J.C. (1999)
    1399. Cytokine regulation of CD40 expression in fetal human astrocyte cultures. (PubMed id 10580808)9 Abdel-Haq N....Lyman W.D. (1999)
    1400. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. (PubMed id 10357816)9 Grell M....Strasser A. (1999)
    1401. TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105. (PubMed id 9950430)9 Belich M.P.... Ley S.C. (1999)
    1402. Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells. (PubMed id 10508274)9 Sakata N....Gelfand E.W. (1999)
    1403. Glucocorticoids affect human dendritic cell differentiation and maturation. (PubMed id 10352262)9 Piemonti L....Di Carlo V. (1999)
    1404. Extracellular signal-regulated kinase-2, but not c-Jun NH2-terminal kinase, activation correlates with surface IgM-mediated apoptosis in the WEHI 231 B cell line. (PubMed id 9712025)9 Lee J.R. and Koretzky G.A. (1998)
    1405. A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase. (PubMed id 9570524)9 Hatzivassiliou E....Mosialos G. (1998)
    1406. Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells. (PubMed id 9622100)9 Couderc B....Robbins P.D. (1998)
    1407. Low expression of CD40 and B7 on macrophages infiltrating UV-exposed human skin; role in IL-2Ralpha-T cell activation. (PubMed id 9754581)9 Kremer I.B....Stevens S.R. (1998)
    1408. Chronic lymphocytic leukemia B cells can express CD40 ligand and demonstrate T-cell type costimulatory capacity. (PubMed id 9531577)9 Schattner E.J....Crow M.K. (1998)
    1409. Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells. (PubMed id 9680368)9 Romano M.F....Venuta S. (1998)
    1410. Chronic antagonism of nuclear factor-kappaB activity in cytotrophoblasts by dexamethasone: a potential mechanism for antiinflammatory action of glucocorticoids in human placenta. (PubMed id 9768679)9 Rosen T....Guller S. (1998)
    1411. Impairment of B-lymphocyte differentiation induced by dual triggering of the B-cell antigen receptor and CD40 in advanced HIV-1-disease. (PubMed id 9727564)9 Conge A.M....Vendrell J.P. (1998)
    1412. Functional competence of dendritic cells in human umbilical cord blood. (PubMed id 9715887)9 Sorg R.V....Wernet P. (1998)
    1413. CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner. (PubMed id 9469427)9 McDyer J.F....Seder R.A. (1998)
    1414. Immunotherapy for autoimmune and inflammatory renal diseases. (PubMed id 9617563)9 Jayne D.R. (1998)
    1415. Bacterial lipopolysaccharide contamination of commercial collagen preparations may mediate dendritic cell maturation in culture. (PubMed id 9692867)9 Suri R.M. and Austyn J.M. (1998)
    1416. Nf-kappa B: an important transcription factor in photobiology. (PubMed id 9819895)9 Legrand-Poels S....Piette J. (1998)
    1417. Cetirizine and hydrocortisone differentially regulate ICAM-1 expression and chemokine release in cultured human keratinocytes. (PubMed id 9537772)9 Albanesi C....Girolomoni G. (1998)
    1418. Detection of CD40 on human thyroid follicular cells: analysis of expression and function. (PubMed id 9543155)9 Metcalfe R.A....Weetman A.P. (1998)
    1419. Evidence for a critical role for IL-2 in CD40-mediate d activation of naive B cells by primary CD4 T cells. (PubMed id 9794390)9 Johnson-LAcger C....Klaus G.G. (1998)
    1420. CD40 stimulation inhibits cell growth and Fas-mediated apoptosis in a thyroid cancer cell line. (PubMed id 10223618)9 Fujieda S....Saito H. (1998)
    1421. Expression of inducible lymphocyte costimulatory molecules in human renal allograft. (PubMed id 9550652)9 Biancone L....Camussi G. (1998)
    1422. Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons. (PubMed id 9852573)9 Maggirwar S.B....Freeman R.S. (1998)
    1423. Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand. (PubMed id 9763568)9 Baker M.P....Gordon J. (1998)
    1424. CD40 ligand and autoantigen are involved in the pathogenesis of low-grade B-cell lymphomas of mucosa-associated lymphoid tissue. (PubMed id 9814592)9 Greiner A....Muller-Hermelink H.K. (1998)
    1425. NF-kappaB activation in CD27 signaling: involvement of TNF receptor-associated factors in its signaling and identification of functional region of CD27. (PubMed id 9794406)9 Yamamoto H....Minamoto S. (1998)
    1426. Substance P enhances cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) expression on cultured rheumatoid fibroblast-like synoviocytes. (PubMed id 9717978)9 Lambert N....Cantagrel A. (1998)
    1427. Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia. (PubMed id 9450802)9 Younes A....Andreeff M. (1998)
    1428. The A-Myb transcription factor is a marker of centroblasts in vivo. (PubMed id 9510180)9 Golay J....Introna M. (1998)
    1429. Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells. (PubMed id 9831176)9 van der Velden V.H....Versnel M. (1998)
    1430. Signaling pathways mediated by the TNF- and cytokine-receptor families target a common cis-element of the IFN regulatory factor 1 promoter. (PubMed id 9834081)9 Gupta S....Pernis A.B. (1998)
    1431. In vitro positive selection and anergy induction of class II-restricted TCR transgenic thymocytes by a cortical thymic epithelial cell line. (PubMed id 9786433)9 Nelson A.J....Farr A.G. (1998)
    1432. Synergistic regulation of inducible nitric oxide synthase gene by CCAAT/enhancer-binding protein beta and nuclear factor-kappaB in hepatocytes. (PubMed id 9685183)9 Sakitani K....Ito S. (1998)
    1433. CD27/CD70 interaction augments IgE secretion by promoting the differentiation of memory B cells into plasma cells. (PubMed id 9862673)9 Nagumo H....Komiyama A. (1998)
    1434. Mutations of the CD40 ligand gene and its effect on CD40 ligand expression in patients with X-linked hyper IgM syndrome. (PubMed id 9746782)9 Seyama K.... Ochs H.D. (1998)
    1435. Interleukin-1 increases expression of the LYT-10 (NFkappaB2) proto-oncogene/transcription factor in renal cell carcinoma lines. (PubMed id 9523851)9 Kurzrock R....Talpaz M. (1998)
    1436. Structure-based design of immunologically active therapeutic peptides. (PubMed id 9479578)9 Murali R. and Greene M.I. (1998)
    1437. Expression and cytokine regulation of immune recognition elements by normal human biliary epithelial and established liver cell lines in vitro. (PubMed id 9824263)9 Cruickshank S.M....Trejdosiewicz L.K. (1998)
    1438. IL-15 promotes IL-12 production by human monocytes via T cell-dependent contact and may contribute to IL-12-mediated IFN-gamma secretion by CD4+ T cells in the absence of TCR ligation. (PubMed id 9759858)9 Avice M.N....Sarfati M. (1998)
    1439. Establishment and characterization of a novel human rheumatoid fibroblast-like synoviocyte line, MH7A, immortalized with SV40 T antigen. (PubMed id 9832620)9 Miyazawa K....Okudaira H. (1998)
    1440. The role of eosinophils in the pathobiology of Hodgkin's disease. (PubMed id 9209649)9 Pinto A....Carbone A. (1997)
    1441. Functions of CD40 on B cells, dendritic cells and other cells. (PubMed id 9203418)9 van Kooten C. and Banchereau J. (1997)
    1442. In vivo but not in vitro stimulations rescue of the defective class switching to IgG or IgA in B-cells of immunodeficiency with hyper IgM. (PubMed id 9175918)9 Saiki O....Kishimoto T. (1997)
    1443. Selective up-regulation of cytokine-induced RANTES gene expression in lung epithelial cells by overexpression of IkappaBR. (PubMed id 9242696)9 Ray P.... Ray A. (1997)
    1444. B-cell-derived IL-10: production and function. (PubMed id 8990095)9 Burdin N....Banchereau J. (1997)
    1445. Coexpression of CD40 and class II antigen HLA-DR in Graves' disease thyroid epithelial cells. (PubMed id 9245555)9 Faure G.C....Leclere J. (1997)
    1446. Role for CD40-mediated activation of c-Rel and maintenance of c-myc RNA levels in mitigating anti-IgM-induced growth arrest. (PubMed id 9344491)9 Siebelt F....Clark E.A. (1997)
    1447. Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation. (PubMed id 9137085)9 Greiner A....MA1ller-Hermelink H.K. (1997)
    1448. Maintenance of human germinal center B cells in vitro. (PubMed id 9028323)9 Pound J.D. and Gordon J. (1997)
    1449. Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells. (PubMed id 9185524)9 Kochetkova M....Shannon M.F. (1997)
    1450. Soluble CD16/Fc gamma RIII induces maturation of dend ritic cells and production of several cytokines including IL-12. (PubMed id 9286384)9 de la Salle H....Hanau D. (1997)
    1451. CD40 expression by gingival fibroblasts: correlation of phenotype with function. (PubMed id 9310826)9 Dongari-Bagtzoglou A.I....Ebersole J.L. (1997)
    1452. Immunohistochemical analysis of in vivo patterns of TRAF-3 expression, a member of the TNF receptor-associated factor family. (PubMed id 9550380)9 Krajewski S....Reed J.C. (1997)
    1453. Identification of amino acid residues important for ligand binding to Fas. (PubMed id 9126929)9 Starling G.C....Kiener P.A. (1997)
    1454. Nuclear Rel-A and c-Rel protein complexes are differentially distributed within human thymocytes. (PubMed id 9058790)9 Feuillard J....Korner M. (1997)
    1455. Dendritic cells in the T-cell areas of lymphoid organs. (PubMed id 9176697)9 Steinman R.M....Inaba K. (1997)
    1456. Cloning, expression and biological function of the bovine CD40 homologue: role in B-lymphocyte growth and differentiation in cattle. (PubMed id 9135560)9 Hirano A....Estes D.M. (1997)
    1457. Cyclic-AMP modulates downstream events in CD40-mediated signal transduction, but inhibition of protein kinase A has no direct effect on CD40 signaling. (PubMed id 9550383)9 Goldstein M.D....Watts T.H. (1997)
    1458. The human T-cell leukemia virus type 1 transactivator protein Tax colocalizes in unique nuclear structures with NF-kappaB proteins. (PubMed id 9094620)9 Bex F....Gaynor R. (1997)
    1459. Germinal center B cells rescued from apoptosis by CD40 ligation or attachment to follicular dendritic cells, but not by engagement of surface immunoglobulin or adhesion receptors, become resistant to CD95-induced apoptosis. (PubMed id 9021991)9 Koopman G....Pals S.T. (1997)
    1460. Multiple redox regulation in NF-kappaB transcription factor activation. (PubMed id 9426183)9 Piette J....Bours V. (1997)
    1461. HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas. (PubMed id 9359699)9 Moses A.V....Nelson J.A. (1997)
    1462. Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes. (PubMed id 9570146)9 Xia C....Woo P. (1997)
    1463. Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1. (PubMed id 9374108)9 Atsuta J....Schleimer R.P. (1997)
    1464. Abnormal CD40-mediated activation pathway in B lymphocytes from patients with hyper-IgM syndrome and normal CD40 ligand expression. (PubMed id 9058789)9 Durandy A....Fischer A. (1997)
    1465. Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity. (PubMed id 9388261)9 Ueda A....Yoshimura T. (1997)
    1466. [The essential region of CD40 cytoplasmic domain for signal transduction in WEHI231 cells] (PubMed id 9226470)9 Hara T. (1997)
    1467. Antibodies against sialophorin (CD43) enhance the capacity of dendritic cells to cluster and activate T lymphocytes. (PubMed id 9278308)9 Fanales-Belasio E....Girolomoni G. (1997)
    1468. IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis. (PubMed id 9218603)9 Poe J.C....Suttles J. (1997)
    1469. The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease. (PubMed id 9208060)9 Diaz-Sanchez D. (1997)
    1470. [The dendritic cell differentiation and antigen-presenting function of the erythroleukemia cells induced by GM-CSF] (PubMed id 9772515)9 Zhao Y. and Cao X. (1997)
    1471. Functional CD40 ligand is expressed by T cells in rheumatoid arthritis. (PubMed id 9410920)9 MacDonald K.P....Thomas R. (1997)
    1472. p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes. (PubMed id 9310830)9 Poggi A....Moretta L. (1997)
    1473. Possible role of nuclear factor-kappa B activity in germline C epsilon transcription in a human Burkitt lymphoma B cell line. (PubMed id 9070319)9 Yanagihara Y....Kajiwara K. (1997)
    1474. [The TRAF family protein-mediated B cell proliferation signal and the mechanism of LMP1-induced B cell transformation] (PubMed id 9046814)9 Inoue J. (1997)
    1475. Ligation of CD40 potentiates Fas-mediated activation of the cysteine protease CPP32, cleavage of its death substrate PARP, and apoptosis in Ramos-Burkitt lymphoma B cells. (PubMed id 9398401)9 An S....Knox K.A. (1997)
    1476. Human thyroid fibroblasts exhibit a distinctive phenotype in culture: characteristic ganglioside profile and functional CD40 expression. (PubMed id 9389546)9 Smith T.J....Phipps R.P. (1997)
    1477. Expression and function of Fas (CD95) on human renal tubular epithelial cells. (PubMed id 9335379)9 Boonstra J.G....van Kooten C. (1997)
    1478. CD40 ligation on human cord blood CD34+ hematopoietic progenitors induces their proliferation and differentiation into functional de ndritic cells. (PubMed id 9016882)9 Flores-Romo L....Banchereau J. (1997)
    1479. Expression and function of OX40 ligand on human dendritic cells. (PubMed id 9378971)9 Ohshima Y....Delespesse G. (1997)
    1480. Induction of interleukin-12 p40 transcript by CD40 ligation via activation of nuclear factor-kappaB. (PubMed id 9464836)9 Yoshimoto T....Nariuchi H. (1997)
    1481. Requirement of a second signal via protein kinase C o r protein kinase A for maximal expression of CD40 ligand. Involvement of transc riptional and posttranscriptional mechanisms. (PubMed id 9394805)9 SuA!rez A....Gutierrez C. (1997)
    1482. Constitutive expression of p50 homodimer in freshly isolated human monocytes decreases with in vitro and in vivo differentiation: a possible mechanism influencing human immunodeficiency virus replication in monocytes and mature macrophages. (PubMed id 9032344)9 Lewin S.R....Crowe S.M. (1997)
    1483. Role of cyclic AMP in the modulation of IgE productio n by the beta 2-adrenoceptor agonist, fenoterol. (PubMed id 8777955)9 Coqueret O....Lagente V. (1996)
    1484. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. (PubMed id 8871635)9 Sutherland C.L....Gold M.R. (1996)
    1485. The hematopoietic development of dendritic cells: a distinct pathway for myeloid differentiation. (PubMed id 8843539)9 Young J.W. and Steinman R.M. (1996)
    1486. Inhibition of nuclear factor kappa B subunit p65 mRNA accumulation in lipopolysaccharide-stimulated human monocytic cells treated with sodium salicylate. (PubMed id 9467376)9 Takashiba S....Amar S. (1996)
    1487. CD48 delivers an accessory signal for CD40-mediated activation of human B cells. (PubMed id 8929458)9 Klyushnenkova E.N....Choi Y.S. (1996)
    1488. Diagnostic significance of CD40, CD40L, and CD26 expression in Hodgkin's disease and other lymphomas. (PubMed id 8604696)9 Carbone A. and Gloghini A. (1996)
    1489. Molecular pathology of the X-linked hyper-immunoglobulin M syndrome: detection of wild-type transcripts in a patient with a complex splicing defect of the CD40 ligand. (PubMed id 8914765)9 Ameratunga R....Marbrook J. (1996)
    1490. The mechanism of action of cyclosporin A and FK506. (PubMed id 8811062)9 Ho S....Crabtree G.R. (1996)
    1491. The role of current and new discriminating markers in the immunodiagnosis of Hodgkin's disease and other phenotypically related lymphomas. (PubMed id 8916443)9 Carbone A. and Gloghini A. (1996)
    1492. Recent advances in tumor necrosis factor and CD40 signaling. (PubMed id 8791485)9 Tewari M. and Dixit V.M. (1996)
    1493. Increase of intracellular calcium is the essential si gnal for the expression of CD40 ligand. (PubMed id 8625977)9 NA1sslein H.G....Manger B. (1996)
    1494. Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation. (PubMed id 8639842)9 Tuscano J....Kehrl J.H. (1996)
    1495. A dual role for both CD40-ligand and TNF-alpha in controlling human B cell death. (PubMed id 8543800)9 Lens S.M....van Lier R.A. (1996)
    1496. Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes. (PubMed id 8666776)9 Burdin N....Rousset F. (1996)
    1497. Expression of CD95 antigen and Bcl-2 protein in non-Hodgkin's lymphomas and Hodgkin's disease. (PubMed id 8774139)9 Nguyen P.L....Robertson M.J. (1996)
    1498. Distinct mechanisms for rescue from apoptosis in Ramos human B cells by signaling through CD40 and interleukin-4 receptor: role for inhibition of an early response gene, Berg36. (PubMed id 8898945)9 Ning Z.Q.... Murphy J.J. (1996)
    1499. Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation. (PubMed id 8940164)9 Roshak A.K....Marshall L.A. (1996)
    1500. The role of the CD40 antigen on malignant B cells. (PubMed id 8819071)9 Planken E.V....Kluin-Nelemans J.C. (1996)
    1501. Naive (CD45RA+) T lymphocytes are more sensitive to oxidative stress-induced signals than memory (CD45RO+) cells. (PubMed id 8912888)9 Lahdenpohja N. and Hurme M. (1996)
    1502. Signals leading to the activation of NF-kappa B trans cription factor are stronger in neonatal than adult T lymphocytes. (PubMed id 8693296)9 Kilpinen S....Hurme M. (1996)
    1503. CD11a-CD18 and CD102 interactions mediate human myeloma cell growth arrest induced by CD40 stimulation. (PubMed id 8620513)9 Pellat-Deceunynck C....Bataille R. (1996)
    1504. TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor. (PubMed id 8663299)9 Nakano H.... Okumura K. (1996)
    1505. CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator. (PubMed id 8950992)9 Eliopoulos A.G....Young L.S. (1996)
    1506. Functional CD40 ligand expressed by human blood dendritic cells is up-regulated by CD40 ligation. (PubMed id 8906811)9 Pinchuk L.M....Clark E.A. (1996)
    1507. Follicular dendritic cells adhere to fibronectin and laminin fibers via their respective receptors. (PubMed id 8874197)9 Ogata T....Takahashi T. (1996)
    1508. Stimulation of human lymphocyte proliferation and CD40 antigen expression by phosphorothioate oligonucleotides complementary to hepatitis B virus genome. (PubMed id 8871877)9 Chen C....Feng Z. (1996)
    1509. High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters. (PubMed id 8934574)9 Himes S.R....Shannon M.F. (1996)
    1510. CD40 expression by human peripheral blood eosinophils. (PubMed id 8601642)9 Ohkawara Y....Jordana M. (1996)
    1511. A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein. (PubMed id 8660894)9 Wang X....Lacy E. (1996)
    1512. I-TRAF is a novel TRAF-interacting protein that regulates TRAF- mediated signal transduction. (PubMed id 8710854)9 Rothe M....Goeddel D.V. (1996)
    1513. [Mechanism and regulation of IgE production in allergy] (PubMed id 8838093)9 Kurasawa K. and Iwamoto I. (1996)
    1514. Genomic structure and PCR-SSCP analysis of the human CD40 ligand gene: its application to prenatal screening for X-linked hyper-IgM syndrome. (PubMed id 8566950)9 Seyama K....Kominami E. (1996)
    1515. Suppression of human immunoglobulin E antibody production by a new naphthalene derivative. (PubMed id 8530258)9 Uejima Y....Ochs H.D. (1995)
    1516. Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen. (PubMed id 7541711)9 Francisco J.A....Siegall C.B. (1995)
    1517. Activation of B lymphocyte maturation by a human follicular dendritic cell line, FDC-1. (PubMed id 7608535)9 Clark E.A....Shu G.L. (1995)
    1518. Tumour dormancy and cell signalling--III: Role of hyp ercrosslinking of IgM and CD40 on the induction of cell cycle arrest and apopto sis in B lymphoma cells. (PubMed id 8885131)9 Marches R....Uhr J.W. (1995)
    1519. B cells from a distinct subset of patients with common variable immunodeficiency (CVID) have increased CD95 (Apo-1/fas), diminished CD38 expression, and undergo enhanced apoptosis. (PubMed id 7554385)9 Saxon A....Sidell N. (1995)
    1520. A subset of CD4+ memory T cells contains preformed CD 40 ligand that is rapidly but transiently expressed on their surface after acti vation through the T cell receptor complex. (PubMed id 7699321)9 Casamayor-Palleja M....MacLennan I.C. (1995)
    1521. Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. (PubMed id 7534792)9 Sen J....Sen R. (1995)
    1522. The expression of CD26 and CD40 ligand is mutually exclusive in human T-cell non-Hodgkin's lymphomas/leukemias. (PubMed id 8541553)9 Carbone A....Pinto A. (1995)
    1523. The CD40 ligand expressed by human B cells costimulates B cell responses. (PubMed id 7537298)9 Grammer A.C....Lipsky P.E. (1995)
    1524. Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals. (PubMed id 7500031)9 Yellin M.J....Chess L. (1995)
    1525. Cell type-specific transactivation of the VCAM-1 promoter through an NF-kappa B enhancer motif. (PubMed id 7536741)9 Ahmad M....Medford R.M. (1995)
    1526. Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. (PubMed id 7530508)9 Carbone A....Pinto A. (1995)
    1527. [Effects of beta-adrenergic compounds on IgE production] (PubMed id 8588826)9 Coqueret O. and Lagente V. (1995)
    1528. Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonists in human newborns. (PubMed id 7530739)9 Durandy A....Fischer A. (1995)
    1529. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. (PubMed id 7539037)9 Katsikis P.D....Herzenberg L.A. (1995)
    1530. Molecular mechanism in tolerance to lipopolysaccharide. (PubMed id 7583350)9 Ziegler-Heitbrock H.W. (1995)
    1531. IL-4 plus CD40 monoclonal antibody induces human B cells gamma subclass-specific isotype switch: switching to gamma 1, gamma 3, and gamma 4, but not gamma 2. (PubMed id 7544371)9 Fujieda S....Saxon A. (1995)
    1532. Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. (PubMed id 7907604)9 Fuleihan R....Geha R.S. (1994)
    1533. Kinetics of the pleiotropic effect of interleukin 4 on the surface properties of human B-lymphoma cells. (PubMed id 7866283)9 Shubinsky G. and Schlesinger M. (1994)
    1534. The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization. (PubMed id 7510691)9 Okamoto S....Matsushima K. (1994)
    1535. Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes. (PubMed id 7522246)9 Kim H.S....Choi Y.S. (1994)
    1536. Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2. (PubMed id 7507510)9 Ren C.L....Geha R.S. (1994)
    1537. NF-kappa B/Rel family members are physically associated phosphoproteins. (PubMed id 7980409)9 Li C.C....Longo D.L. (1994)
    1538. Activation of the transcription factor NF-KB in GH3 p ituitary cells. (PubMed id 7895918)9 Grandison L....Pfaff D.W. (1994)
    1539. Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. (PubMed id 7518925)9 Boussiotis V.A....Goldfeld A.E. (1994)
    1540. CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency. (PubMed id 7508119)9 Farrington M....Ochs H.D. (1994)
    1541. Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cells. (PubMed id 8046339)9 Loh R.K....Geha R.S. (1994)
    1542. Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes. (PubMed id 8114727)9 Johnson J.L.... Toft D.O. (1994)
    1543. Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription. (PubMed id 8139561)9 Hansen S.K....Blasi F. (1994)
    1544. Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions. (PubMed id 7519240)9 Clement M.V. and Stamenkovic I. (1994)
    1545. Establishment and characterization of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production. (PubMed id 7514905)9 FernA!ndez E....Toribio M.L. (1994)
    1546. Prodynorphin gene expression relates to NF-kappa B factors. (PubMed id 7968369)9 Bakalkin G....Terenius L. (1994)
    1547. Visualization of the endogenous NF-kappa B p50 subunit in the nucleus of follicular dendritic cells in germinal centers. (PubMed id 8254185)9 Feuillard J....Raphael M. (1994)
    1548. [Regulation of the production of IgE in man] (PubMed id 7527216)9 Dessaint J.P. and Labalette M. (1994)
    1549. Long-term inositol phosphate release, but not tyrosine kinase activity, correlates with IL-2 secretion and NF-AT induction in anti-CD3-activated peripheral human T lymphocytes. (PubMed id 8039243)9 Bryan R.G....Rich R.R. (1994)
    1550. CD58 (LFA-3) stimulation provides a signal for human isotype switching and IgE production distinct from CD40. (PubMed id 7515920)9 Diaz-Sanchez D....Saxon A. (1994)
    1551. Characterization of ligand binding by the human p55 tumour-necrosis-factor receptor. Involvement of individual cysteine-rich repeats. (PubMed id 8055960)9 Corcoran A.E....Feldmann M. (1994)
    1552. Regulation of CD40 ligand expression and use of recombinant CD40 ligand for studying B cell growth and differentiation. (PubMed id 7865800)9 Kehry M.R. and Castle B.E. (1994)
    1553. Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor. (PubMed id 8152812)9 Beg A.A. and Baldwin A.S. Jr. (1994)
    1554. Enhancement of Ig