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CD302 Gene

protein-coding   GIFtS: 45
GCID: GC02M160625

CD302 Molecule

(Previous name: CD302 antigen)
  See related diseases
at
MalaCards
 

Aliases
for CD302 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD302 Molecule1 2     C-Type Lectin Domain Family 131
CD302 Antigen1 2 3     Member A1
DCL12 3 5     BIMLEC2
Type I Transmembrane C-Type Lectin Receptor DCL-12 3     DCL-12
CLEC13A2 3     C-Type Lectin Domain Family 13, Member A2
DEC205-Associated C-Type Lectin 12 3     C-Type Lectin BIMLEC3
KIAA00223 5     C-Type Lectin Domain Family 13 Member A3

External Ids:    HGNC: 308431   Entrez Gene: 99362   Ensembl: ENSG000002413997   OMIM: 6122465   UniProtKB: Q8IX053   

Export aliases for CD302 gene to outside databases

Previous GC identifers: GC02M160451 GC02M160333 GC02M152509


Summaries
for CD302 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CD302 Gene:
CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis
(Kato et al., 2007 (PubMed 17947679)).(supplied by OMIM, Aug 2008)

GeneCards Summary for CD302 Gene:
CD302 (CD302 molecule) is a protein-coding gene. Diseases associated with CD302 include hepatitis b, and hodgkin's lymphoma. GO annotations related to this gene include carbohydrate binding.

UniProtKB/Swiss-Prot: CD302_HUMAN, Q8IX05
Function: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as
well as in cell adhesion and migration

Gene Wiki entry for CD302 Gene


Genomic Views
for CD302 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD302 gene promoter:
         TBP   Pbx1a   LUN-1   CUTL1   C/EBPalpha   FAC1   POU2F1   POU2F1a   IRF-7A   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CD302 promoter sequence
   Search Chromatin IP Primers for CD302

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD302


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.2   Ensembl cytogenetic band:  2q24.2   HGNC cytogenetic band: 2q24.2

CD302 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD302 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M160625:  view genomic region     (about GC identifiers)

Start:
 160,625,139 bp from pter      End:
 160,654,766 bp from pter
Size:
 29,628 bases      Orientation:
 minus strand

Proteins
for CD302 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CD302_HUMAN, Q8IX05 (See protein sequence)
Recommended Name: CD302 antigen precursor  
Size: 232 amino acids; 26183 Da
Developmental stage: Expressed at relatively high levels in fetal lung, liver, spleen and kidney with lower
expression levels detected in heart, thymus and brain
Miscellaneous: Isoform 2 and isoform 3 are produced in HRS cells by a transcriptional control mechanism which
cotranscribe an mRNA containing LY75 and CD302 prior to generating the intergenically spliced mRNA to produce
LY75/CD302 fusion proteins
Secondary accessions: A8K5G4 B4E2T9 Q15009
Alternative splicing: 5 isoforms:  Q8IX05-1   O60449-1   Q8IX05-2   O60449-2   O60449-3   (Produced by intergenic splicing of LY75 and CD302)

Explore the universe of human proteins at neXtProt for CD302: NX_Q8IX05

Explore proteomics data for CD302 at MOPED

Post-translational modifications: 

  • May be heterogeneously N-glycosylated in some cell types1
  • Glycosylation2 at Asn109
  • Modification sites at PhosphoSitePlus

    • See CD302 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001185692.1  NP_001185693.1  NP_055695.2  

    ENSEMBL proteins: 
     ENSP00000259053   ENSP00000394301  

    CD302 Human Recombinant Protein Products:

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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CD302
    OriGene Protein Over-expression Lysate for CD302
    OriGene MassSpec for CD302
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    Novus Biologicals CD302 Proteins
    Novus Biologicals CD302 Lysate
    Sino Biological Recombinant Protein for CD302
    Sino Biological Cell Lysate for CD302
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    CD302 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CD302 (CD302/CLEC13A)
    OriGene Antibodies for CD302
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    Novus Biologicals CD302 Antibody
    Abcam antibodies for CD302
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for CD302
    LSBio Antibodies in human, mouse, rat for CD302

    CD302 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CD302
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CD302
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.

    Domains /
    Families
    for CD302 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 HGNC Gene Families:
    CD: CD molecules
    CLEC: C-type lectin domain containing

    3 InterPro protein domains:
     IPR016187 C-type_lectin_fold
     IPR016186 C-type_lectin-like
     IPR001304 C-type_lectin

    Graphical View of Domain Structure for InterPro Entry Q8IX05

    ProtoNet protein and cluster: Q8IX05

    UniProtKB/Swiss-Prot: CD302_HUMAN, Q8IX05
    Similarity: Contains 1 C-type lectin domain


    CD302 for domains           About GeneDecksing


    Function
    for CD302 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CD302_HUMAN, Q8IX05
    Function: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as
    well as in cell adhesion and migration

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030246carbohydrate binding IEA--
         
    CD302 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD302
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CD302

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD302
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD302

    miRNA
    Products:            		miRTarBase miRNAs that target CD302:
    hsa-mir-23a-3p (MIRT050420), hsa-mir-23b-3p (MIRT046309)

    Block miRNA regulation of human, mouse, rat CD302 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD302 (see all 9):
    hsa-miR-3163 hsa-miR-3690 hsa-miR-607 hsa-miR-548p hsa-miR-4282 hsa-miR-744* hsa-miR-33a hsa-miR-3927
    SwitchGear 3'UTR luciferase reporter plasmid: CD302 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for CD302
    Predesigned siRNA for gene silencing in human, mouse, rat CD302

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CD302

    Clone
    Products:             		 OriGene clones in human, mouse for CD302 (see all 14)
    OriGene ORF clones in mouse, rat for CD302
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): CD302 (NM_001198763)
    Sino Biological Human cDNA Clone for CD302
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD302
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD302

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CD302
    Browse ESI BIO Cell Lines and PureStem Progenitors for CD302 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD302


    Localization
    for CD302 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CD302_HUMAN, Q8IX05: Membrane; Single-pass type I membrane protein (Potential). Cell projection, filopodium.
    Cytoplasm, cell cortex. Cell projection, microvillus. Note=Colocalizes with F-actin in filopodia, cellular cortex
    and microvilli of the apical cell surface
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane2
    endoplasmic reticulum1
    extracellular1
    golgi apparatus1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005902microvillus IEA--
    GO:0005938cell cortex IDA17947679
    GO:0016021integral component of membrane IEA--
    GO:0030175filopodium IDA17947679

    CD302 for ontologies           About GeneDecksing


    Pathways & Interactions
    for CD302 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CD302
    Interactions:

        Search GeneGlobe Interaction Network for CD302

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006909phagocytosis IDA17947679

    CD302 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CD302 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CD302



    Transcripts
    for CD302 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CD302 gene (3 alternative transcripts): 
    NM_001198763.1  NM_001198764.1  NM_014880.4  

    Unigene Cluster for CD302:

    CD302 molecule
    Hs.130014  [show with all ESTs]
    Unigene Representative Sequence: NM_014880
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000259053(uc002uba.3 uc021vrt.1 uc010zco.2) ENST00000480212
    ENST00000429078
    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat CD302 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD302 (see all 9):
    hsa-miR-3163 hsa-miR-3690 hsa-miR-607 hsa-miR-548p hsa-miR-4282 hsa-miR-744* hsa-miR-33a hsa-miR-3927
    SwitchGear 3'UTR luciferase reporter plasmid: CD302 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for CD302
    Predesigned siRNA for gene silencing in human, mouse, rat CD302
    Clone
    Products:             		 OriGene clones in human, mouse for CD302 (see all 14)
    OriGene ORF clones in mouse, rat for CD302
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): CD302 (NM_001198763)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD302
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD302
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for CD302
    OriGene qSTAR qPCR primer pairs in human, mouse for CD302
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD302
      QuantiTect SYBR Green Assays in human, mouse, rat CD302
      QuantiFast Probe-based Assays in human, mouse, rat CD302

    Additional mRNA sequence: 

    AF499000.1 AK291279.1 AK304422.1 AY314007.1 BC020646.1 D14664.1 

    6 DOTS entries:

    DT.75180760  DT.95075642  DT.416796  DT.120993629  DT.99960501  DT.120993672 

    Selected AceView cDNA sequences (see all 253):

    AY184222 AI827135 BM273105 CD244765 AI621101 AU185108 AI984719 BG057185 
    CK820033 AW949721 BI966750 AY314006 AW297924 AI865076 AW611786 AI285871 
    AA279177 AA279284 BX103829 AA364840 BI027069 AI955903 BM354053 D57864 

    GeneLoc Exon Structure


    Expression
    for CD302 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CD302 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CD302 Expression
    About this image


    CD302 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Lung (Respiratory System)
             Alveolar type II cells
     
     Adipose (Muscoskeletal System)
             White adipocyte-like cells
     
     Liver (Hepatobiliary System)
             Hepatocyte-like cells
    CD302 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    CD302 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.130014

    UniProtKB/Swiss-Prot: CD302_HUMAN, Q8IX05
    Tissue specificity: Expressed at moderate levels in monocytes, myeloid blood dendritic cells and granulocytes and
    at low levels in plasmacytoid blood dendritic cells, monocyte-derived ma crophages and monocyte-derived dendritic
    cells, with no expression detected in T-lymphocytes, B-lymphocytes and natural killer cells (at protein level).
    Expressed widely in different tissues, with highest expression levels in liver, lung, peripheral blood leukocytes
    and spleen, and lowest levels in neuronal tissues, skeletal muscle and ovary. Isoform 2 and isoform 3 are
    expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells

        Custom PCR Arrays for CD302
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    QuantiFast Probe-based Assays in human, mouse, rat CD302
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD302

    Orthologs
    for CD302 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CD302 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cd3021 , 5 CD302 antigen1, 5 82.58(n)1
    76.38(a)1    		   2 (34.50 cM)5
    662051  NM_025422.31  NP_079698.21 
     602519935 
    lizard
    (Anolis carolinensis)    		 Reptilia CD3026
    		 CD302 molecule
    		 41(a)
    		 1 ↔ 1
    		 GL343371.1(922319-927341)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1003336851 CD302 antigen-like 47.69(n)
    35.15(a)    		   100333685  XM_002667634.3  XP_002667680.1 


    ENSEMBL Gene Tree for CD302 (if available)
    TreeFam Gene Tree for CD302 (if available)

    Paralogs
    for CD302 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus    		  --

    Genomic Variants
    for CD302 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

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    1 SNPs for CD302    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs340689331,2,4
    		----see VAR_0501012 mis40--------

    HapMap Linkage Disequilibrium report for CD302 (160625139 - 160654766 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CD302:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1001679CNV Deletion20482838
    nsv470497CNV Loss18288195
    dgv4351n71CNV Loss21882294
    nsv875344CNV Loss21882294
    nsv834436CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CD302
    DNA2.0 Custom Variant and Variant Library Synthesis for CD302

    Disorders / Diseases
    for CD302 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 612246    OMIM disorders: --

    4 diseases for CD302:    
    About MalaCards
    hepatitis b    hodgkin's lymphoma    hepatitis    neuronitis


    CD302 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: CD302 (1 document)

    Export disorders for CD302 gene to outside databases

    Publications
    for CD302 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for CD302 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with CD302)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2, 3 Nomura N.... Tabata S. (DNA Res. 1994)
    2. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1. (PubMed id 12824192)1, 2, 9 Kato M.... Hart D.N.J. (J. Biol. Chem. 2003)
    3. The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration. (PubMed id 17947679)1, 2, 9 Kato M.... Hart D.N. (J. Immunol. 2007)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). (PubMed id 7584028)1, 3 Nomura N....Tabata S. (DNA Res. 1994)
    7. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    8. DLC1 negatively regulates angiogenesis in a paracrine fashion. (PubMed id 20861185)1 Shih Y.P....Lo S.H. (Cancer Res. 2010)
    9. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. (PubMed id 20921139)1 Di Bartolomeo S....Fimia G.M. (J. Cell Biol. 2010)
    10. Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level. (PubMed id 19317456)1 Yang S.... Yang D. (Biochemistry 2009)

    External Searches for CD302 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CD302 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 9936 HGNC: 30843 AceView: LY75andDCL-1 Ensembl:ENSG00000241399 euGenes: HUgn9936
    ECgene: CD302 H-InvDB: CD302

    Other Databases showing CD302 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0022

    Specialized Databases showing CD302 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CD302 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CD302 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for CD302 gene:
    Search GeneIP for patents involving CD302

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for CD302 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     EMD Millipore genomic analysis products

      
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     OriGene ORF clones in mouse, rat for CD302   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CD302   OriGene Custom Protein Services for CD302  

         		 
     Block miRNA regulation of human, mouse, rat CD302 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CD302
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD302 Predesigned siRNA for gene silencing in human, mouse, rat CD302
     QuantiFast Probe-based Assays in human, mouse, rat CD302 QuantiTect SYBR Green Assays in human, mouse, rat CD302
     Custom PCR Arrays for CD302 Search Chromatin IP Primers for CD302
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     Search Tocris compounds for CD302
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
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     Browse ESI BIO Cell Lines and PureStem Progenitors for CD302
     Gene Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD302
     SwitchGear 3'UTR luciferase reporter plasmids for CD302
     SwitchGear Promoter luciferase reporter plasmids for CD302
     ThermoFisher Antibodies for CD302
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD302
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD302
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CD302
     LSBio Antibodies in human, mouse, rat for CD302
    Customized transgenic rodents for:
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