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CD300LG Gene

protein-coding   GIFtS: 46
GCID: GC17P041924

CD300 Molecule-Like Family Member G

(Previous name: CD300 antigen like family member G)
  Search for CD300LG
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD300 Molecule-Like Family Member G1 2     CD300 Antigen-Like Family Member G2 3
CLM92 3 5     nepmucin1
TREM42 3 5     NEPMUCIN2
CD300 Antigen Like Family Member G1 2     CD300 Molecule Like Family Member G2
Triggering Receptor Expressed On Myeloid Cells 42 3     CMRF35-Like Molecule 92
CLM-92 3     CD300g Antigen3
TREM-42 3     

External Ids:    HGNC: 304551   Entrez Gene: 1468942   Ensembl: ENSG000001616497   OMIM: 6105205   UniProtKB: Q6UXG33   

Export aliases for CD300LG gene to outside databases

Previous GC identifers: GC17P039281 GC17P037688


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CD300LG Gene:
Members of the CD300 (see MIM 606786)-like (CD300L) family, such as CD300LG, are widely expressed on hematopoietic
cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like
domain (Takatsu et al., 2006 (PubMed 16876123)).(supplied by OMIM, Mar 2008)

GeneCards Summary for CD300LG Gene:
CD300LG (CD300 molecule-like family member g) is a protein-coding gene. An important paralog of this gene is CD300A.

UniProtKB/Swiss-Prot: CLM9_HUMAN, Q6UXG3
Function: Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent
manner. Binds lymphocyte (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD300LG gene promoter:
         AREB6   AML1a   Nkx2-5   NF-kappaB1   NF-E2   NF-E2 p45   Pax-4a   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD300LG promoter sequence
   Search Chromatin IP Primers for CD300LG

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD300LG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.31   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21.31

CD300LG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD300LG gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P041924:  view genomic region     (about GC identifiers)

Start:
41,924,516 bp from pter      End:
41,940,997 bp from pter
Size:
16,482 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CLM9_HUMAN, Q6UXG3 (See protein sequence)
Recommended Name: CMRF35-like molecule 9 precursor  
Size: 332 amino acids; 36060 Da
Secondary accessions: B4DNY5 F5H7P9 F8W9M3 Q8IX38 Q8IX39 Q8TA95
Alternative splicing: 5 isoforms:  Q6UXG3-1   Q6UXG3-2   Q6UXG3-3   Q6UXG3-4   Q6UXG3-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CD300LG: NX_Q6UXG3

Explore proteomics data for CD300LG at MOPED

Post-translational modifications: 

  • O-glycosylated with sialylated oligosaccharides (By similarity)1
  • Glycosylation2 at Asn96, Thr137, Thr143, Thr144, Thr155, Thr161, Thr170, Thr171, Thr177, Thr187,
                                 Thr195, Ser196, Thr199, Thr201, Ser202, Thr207, Ser208, Ser213, Ser214, Ser222 (see all 25)
  • Modification sites at PhosphoSitePlus

  • See CD300LG Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001161794.1  NP_001161795.1  NP_001161796.1  NP_660316.2  

    ENSEMBL proteins: 
     ENSP00000366408   ENSP00000442368   ENSP00000465863   ENSP00000293396   ENSP00000468800  
     ENSP00000321005  

    CD300LG Human Recombinant Protein Products:

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    Sino Biological Recombinant Protein for CD300LG
    Sino Biological Cell Lysate for CD300LG
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    Browse Proteins at Cloud-Clone Corp.

     
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    Search eBioscience for ELISAs for CD300LG 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q6UXG3

    ProtoNet protein and cluster: Q6UXG3

    1 Blocks protein domain: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: CLM9_HUMAN, Q6UXG3
    Domain: Ig-like V-type domain mediates binding to lymphocyte (By similarity)
    Similarity: Belongs to the CD300 family
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    Find genes that share domains with CD300LG           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLM9_HUMAN, Q6UXG3
    Function: Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent
    manner. Binds lymphocyte (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CD300LG           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Cd300lg):
     normal 

    Find genes that share phenotypes with CD300LG           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cd300lgtm1Lex for CD300LG

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD300LG
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    miRNA
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    Block miRNA regulation of human, mouse, rat CD300LG using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD300LG (see all 15):
    hsa-miR-676 hsa-miR-330-5p hsa-miR-566 hsa-miR-516b* hsa-miR-650 hsa-miR-1244 hsa-miR-320e hsa-miR-2115
    SwitchGear 3'UTR luciferase reporter plasmidCD300LG 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD300LG


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CLM9_HUMAN, Q6UXG3: Apical cell membrane; Single-pass type I membrane protein. Basolateral cell membrane;
    Single-pass type I membrane protein. Endosome, multivesicular body membrane; Single-pass type I membrane protein
    (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    plasma membrane5
    extracellular2
    cytosol1
    endoplasmic reticulum1
    lysosome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--
    GO:0016323basolateral plasma membrane IEA--
    GO:0016324apical plasma membrane IEA--
    GO:0032585multivesicular body membrane IEA--

    Find genes that share ontologies with CD300LG           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CD300LG
    Interactions:

        Search GeneGlobe Interaction Network for CD300LG

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002376immune system process IEA--

    Find genes that share ontologies with CD300LG           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CD300LG (CLM9)

    1 HMDB Compound for CD300LG    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CD300LG gene (4 alternative transcripts): 
    NM_001168322.1  NM_001168323.1  NM_001168324.1  NM_145273.3  

    Unigene Cluster for CD300LG:

    CD300 molecule-like family member g
    Hs.147313  [show with all ESTs]
    Unigene Representative Sequence: NM_145273
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377203(uc010wil.2 uc010czl.3) ENST00000539718(uc010czk.3)
    ENST00000588884 ENST00000293396(uc002iel.2) ENST00000586233 ENST00000317310(uc002iem.3)
    ENST00000589212
    miRNA
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    Block miRNA regulation of human, mouse, rat CD300LG using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD300LG (see all 15):
    hsa-miR-676 hsa-miR-330-5p hsa-miR-566 hsa-miR-516b* hsa-miR-650 hsa-miR-1244 hsa-miR-320e hsa-miR-2115
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat CD300LG
      QuantiFast Probe-based Assays in human, mouse, rat CD300LG

    Additional mRNA sequence: 

    AF427619.1 AF427620.1 AK298112.1 AK309938.1 AY358364.1 BC025395.2 

    3 DOTS entries:

    DT.430934  DT.99927064  DT.100804611 

    Selected AceView cDNA sequences (see all 31):

    CB997121 CR593329 BX102384 AA412588 Z28836 AA412569 F22780 BE501092 
    BC025395 AI990244 AI208121 AY358364 BX356362 AL042492 BG546890 AI138257 
    NM_145273 AW269220 AF427620 BG723031 AF427619 U70073 BI057838 BI057366 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CD300LG expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCACTGTG
    CD300LG Expression
    About this image

    CD300LG Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CD300LG Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.147313

    UniProtKB/Swiss-Prot: CLM9_HUMAN, Q6UXG3
    Tissue specificity: Highly expressed in heart, skeletal muscle and placenta

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CD300LG gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cd300lg1 , 5 CD300 antigen like family member G1, 5 71.82(n)1
    61.83(a)1
      11 (65.48 cM)5
    526851  NM_001160711.11  NP_001154183.11 
     1020415095 
    chicken
    (Gallus gallus)
    Aves CD300L-S16
    Gallus gallus CD300 antigen-like family member (CD...
    27(a)
    many ↔ many
    18(10690316-10691046)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    20(a)
    many ↔ many
    2(115999765-116005747)
    zebrafish
    (Danio rerio)
    Actinopterygii CD300LG (3 of 5)6
    CD300LG (2 of 5)6
    (see all 5)
    CD300 molecule-like family member g
    (see all 5)
    22(a)
    19(a)
    (see all 5)
    1 ↔ many
    1 ↔ many
    (see all 5)
    1(58482375-58483019) ENSDARG00000088781
    1(58460908-58465872) ENSDARG00000088556


    ENSEMBL Gene Tree for CD300LG (if available)
    TreeFam Gene Tree for CD300LG (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CD300LG gene
    CD300A2  CD300LB2  CD300C2  CD300LF2  CD300LD2  CD300E2  
    2 SIMAP similar genes for CD300LG using alignment to 2 protein entries:     CLM9_HUMAN (see all proteins):
    CD300LB    CD300E

    Find genes that share paralogs with CD300LG           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CD300LG (see all 435)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1898523901,2
    --41922523(+) AGGCCA/GGGCAT 4 -- us2k10--------
    rs1134778831,2
    F--41922565(+) GGAGGT/CCGACG 4 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1396429321,2
    C--41922609(+) AGCCT-/GGACAA 4 -- us2k10--------
    rs1821564161,2
    --41922702(+) GGCTGA/GGGTGG 4 -- us2k10--------
    rs1872248931,2
    --41922733(+) AGTTTA/GAGGCT 4 -- us2k10--------
    rs1455359921,2
    --41922757(+) ATGGCA/GCCACT 4 -- us2k10--------
    rs1484258301,2
    C--41922867(+) CCTAGA/GCTGGA 4 -- us2k10--------
    rs1917148961,2
    --41923014(+) ACTGGG/TTTTCT 4 -- us2k10--------
    rs1424200951,2
    --41923052(+) CCCGAA/CTTCAG 4 -- us2k10--------
    rs1846408651,2
    --41923101(+) ACAGGC/TGTGAG 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for CD300LG (41924516 - 41940997 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CD300LG:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908265CNV Gain21882294

    Human Gene Mutation Database (HGMD): CD300LG
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CD300LG
    DNA2.0 Custom Variant and Variant Library Synthesis for CD300LG

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610520    OMIM disorders: --


    Find genes that share disorders with CD300LG           About GenesLikeMe


    Export disorders for CD300LG gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CD300LG gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with CD300LG)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CD300 antigen like family member G: a novel Ig receptor like protein exclusively expressed on capillary endothelium. (PubMed id 16876123)1, 2, 3, 9 Takatsu H.... Ohno H. (Biochem. Biophys. Res. Commun. 2006)
    2. Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. (PubMed id 16754720)1, 3 Umemoto E....Miyasaka M. (J. Exp. Med. 2006)
    3. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. The CD300 molecules regulate monocyte and dendritic cell functions. (PubMed id 19592130)1 Clark G.J....Hart D.N. (Immunobiology 2009)
    6. The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions. (PubMed id 19359216)1 Clark G.J....Hart D.N. (Trends Immunol. 2009)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 146894 HGNC: 30455 AceView: TREM4 Ensembl:ENSG00000161649 euGenes: HUgn146894
    ECgene: CD300LG H-InvDB: CD300LG

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CD300LG Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CD300LG gene:
    Search GeneIP for patents involving CD300LG

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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