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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CD300E Gene

protein-coding GIFtS: 48
GCID: GC17M072606

CD300e molecule

(Previous names: CD300 antigen like family member E, CD300e antigen )
(Previous symbol: CD300LE)

Explore 5 diseases affiliated with
CD300E via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CD300e Molecule¹ ²		CLM-2² ³
CD300LE¹ ² ³ ⁵		CMRF35-A5² ³
CLM2¹ ² ³ ⁵		IREM-2² ³
IREM2¹ ² ³ ⁵		PIgR-2² ³
CD300e Antigen¹ ² ³		PIgR2² ³
CD300 Antigen Like Family Member E¹ ²		CD300 Antigen-Like Family Member E² ³
Immune Receptor Expressed On Myeloid Cells 2² ³		CMRF35-Like Molecule 2²
Poly-Ig Receptor 2² ³		CMRF35A5³
Polymeric Immunoglobulin Receptor 2² ³

External Ids:	HGNC: 28874¹	Entrez Gene: 342510²	Ensembl: ENSG00000186407⁷	OMIM: 609801⁵	UniProtKB: Q496F6³

Export aliases for CD300E gene to outside databases

Previous GC identifers: GC17M070119 GC17M068017

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD300E:

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The

protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating

receptor. (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6

Function: Probably acts as an activating receptor

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010783.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CD300E gene promoter:
TBP USF1 NRSF form 1 USF2 USF-1:USF-2 NRSF form 2 E47 TFIID USF-1 Hand1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CD300E promoter sequence

Search SABiosciences Chromatin IP Primers for CD300E

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD300E

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1

CD300E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD300E gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M072606: view genomic region (about GC identifiers)

Start:	72,606,026 bp from pter	End:	72,619,897 bp from pter
Size:	13,872 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6 (See protein sequence)

Recommended Name: CMRF35-like molecule 2 precursor

Size: 205 amino acids; 22918 Da

Subunit: Interacts with TYROBP

Subcellular location: Cell membrane; Single-pass type I membrane protein

Secondary accessions: B4DNS1 Q7Z7I3

Explore the universe of human proteins at neXtProt for CD300E: NX_Q496F6

Post-translational modifications:

N-glycosylated¹

View neXtProt modification sites for NX_Q496F6

CD300E Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_852114.2

ENSEMBL proteins:

ENSP00000376395 ENSP00000415488 ENSP00000416642 ENSP00000329942

Reactome Protein details: Q496F6
Human Recombinant Protein Products for CD300E:

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	Uscn Proteins for CD300E

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

CD300E for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CD300E

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CD300E for domains About GeneDecksing

4 InterPro domains/families:

IPR013783 Ig-like_fold

IPR013106 Ig_V-set

IPR007110 Ig-like_dom

IPR003599 Ig_sub

Graphical View of Domain Structure for InterPro Entry Q496F6

ProtoNet protein and cluster: Q496F6

UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6

Similarity: Belongs to the CD300 family

Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: CLM2_HUMAN, Q496F6

Function: Probably acts as an activating receptor

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	--	--

CD300E for ontologies About GeneDecksing

Animal Models:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD300E

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Immune System

Immune System

1.00

Innate Immune System

0.46

Signaling by FGFR

DAP12 interactions

0.76

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Reactome Pathways for CD300E

	DAP12 interactions
	Immune System
	Innate Immune System

CD300E for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CD300E

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CD300E (ENSP00000329942⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TYROBP	ENSP00000262629⁴	STRING: ENSP00000262629

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CD300E
Search CenterWatch for drugs/clinical trials and news about CD300E / CLM2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CD300E gene:

NM_181449.2

Unigene Cluster for CD300E:

CD300e molecule

Hs.158954 [show with all ESTs]

Unigene Representative Sequence: BX648376

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000392619(uc002jlb.2) ENST00000412268 ENST00000426295 ENST00000328630

miRNA Products:		OriGene 3'-UTR Clone: CD300E Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD300E
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		hsa-miR-622 hsa-miR-1205
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD300E
		Sirion Biotech Custom design and validation of potent shRNA sequences against CD300E

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Additional cDNA sequence:

AF395839.1 AK298031.1 AK303545.1 BC100888.1 BC100889.1 BC100890.1 BX648376.1

1 DOTS entry:

DT.75161866

17 AceView cDNA sequences:

CN479411 BM993876 BX648376 CA449920 AF395839 BU681667 NM_181449 BX112992

BV194694 AL598315 AI380107 BX478972 AI889065 CB528671 BF359799 BI060884

BI061023

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CD300E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTGAATTT

About this image

CD300E expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CD300E Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.158954

UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6

Tissue specificity: Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at

protein level)

SABiosciences Custom PCR Arrays for CD300E

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CD300E gene from 3/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CD300LG⁶ CD300L-S1⁶ (see all 4)	Uncharacterized protein (see all 4)	33(a) 27(a) (see all 4)	1 ↔ many possible ortholog (see all 4)	18(10383917-10385506) 18(10380703-10381477)
lizard (Anolis carolinensis)	Reptilia	CD300LG⁶ FAIM3⁶	--	34(a) 24(a)	1 ↔ many possible ortholog	2(116020650-116021999) 2(115999765-116005747)
zebrafish (Danio rerio)	Actinopterygii	CU896655.7⁶ BX927114.2⁶ (see all 11)	--	8(a) 8(a) (see all 11)	many ↔ many many ↔ many (see all 11)	1(59304615-59307631) 1(58441849-58448289)

ENSEMBL Gene Tree for CD300E (if available)
TreeFam Gene Tree for CD300E (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CD300E gene

CD300LG² CD300A² CD300LB² CD300C² CD300LF² CD300LD²

7 SIMAP similar genes for CD300E using alignment to 4 protein entries: CLM2_HUMAN (see all proteins):

CD300C CD300LB CD300LD ADORA3 CD300LF CD300LG

CD300A

CD300E for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs147619195^1,2		--	72605537(+)	`TTTGCA/GATGTT`	1	--	ds500¹		0	--	--	--	--
rs189056896^1,2		--	72605927(+)	`GCATCA/GCTATT`	1	--	ds500¹		0	--	--	--	--
rs116341778^1,2	C,F	--	72605949(+)	`TCTTAG/AACTTC`	1	--	ds500¹		1		WA	118
rs142141621^1,2		--	72606024(+)	`CCATAG/TACACA`	1	--	ut3¹		0	--	--	--	--
rs79564185^1,2	C,F	--	72606090(+)	`AGGGGA/GAAAAA`	1	--	ut3¹		1		EA	120
rs115472585^1,2	F	--	72606189(+)	`TCTTAA/CCTCTT`	1	--	ut3¹		1		WA	118
rs144521330^1,2		--	72606255(+)	`GTGACC/TTTGTG`	1	--	ut3¹		0	--	--	--	--
rs180906788^1,2		--	72606293(+)	`ATCCCA/GGTCCT`	1	--	ut3¹		0	--	--	--	--
rs77437205^1,2	F	--	72606343(+)	`CATGGC/TTCTTG`	1	--	ut3¹		1		EA	120
rs554592^1,2	C,F,O,A,H	--	72606372(-)	`CAGAAT/ACAAAC`	1	--	ut3¹		16		MN NS EA NA WA CSA	976

HapMap Linkage Disequilibrium report for CD300E (72606026 - 72619897 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for CD300E
5 CNVs: 102532 34522 8852 53066 7171

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD300E

DNA2.0 Custom Variant and Variant Library Synthesis for CD300E

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CD300E for disorders           About GeneDecksing

OMIM gene information: 609801    OMIM disorders: --

5 diseases for CD300E:    About MalaCards

lice infestation tungiasis scabies osteoporosis

psoriasis

3 diseases from the University of Copenhagen DISEASES database for CD300E:

Tungiasis Scabies Lice infestation

Human Genome Epidemiology (HuGE) Navigator: CD300E (1 document)

Export disorders for CD300E gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CD300E gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with CD300E)

Utopia: connect your pdf to the dynamic
world of online information

Molecular characterization of a novel immune receptor restricted to the monocytic lineage. (PubMed id 15557162)^{1, 2, 3} Aguilar H....Lopez-Botet M. (2004)
IREM-1 is a novel inhibitory receptor expressed by myeloid cells. (PubMed id 15549731)^{1, 3} Alvarez-Errico D....Lopez-Botet M. (2004)
Functional analysis of the CD300e receptor in human m onocytes and myeloid dendritic cells. (PubMed id 20039296)¹ Brckalo T....LA^pez-Botet M. (2010)
Genome-wide pleiotropy of osteoporosis-related phenot ypes: The Framingham study. (PubMed id 20200953)¹ Karasik D....Demissie S. (2010)
The CD300 molecules regulate monocyte and dendritic c ell functions. (PubMed id 19592130)¹ Clark G.J....Hart D.N. (2009)
The CD300 family of molecules are evolutionarily sign ificant regulators of leukocyte functions. (PubMed id 19359216)¹ Clark G.J....Hart D.N. (2009)
The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)² Sjoeblom T.... Velculescu V.E. (2006)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)² Zody M.C.... Nusbaum C. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 342510	HGNC: 28874	AceView: IREM2	Ensembl:ENSG00000186407	euGenes: HUgn342510
ECgene: CD300E	H-InvDB: CD300E

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CD300E	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CD300E gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CD300E gene:
Search GeneIP for patents involving CD300E

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	EMD Millipore Custom Antibody & Bulk Services
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	Antibodies for CD300E (CD300e/LMIR6)		Browse Cell Culture Products
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	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents for CD300E (CD300e/LMIR6)
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for CD300E
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CD300E		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CD300E
	OriGene Protein Over-expression Lysate for CD300E		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for CD300E		OriGene 3'-UTR Clone for CD300E
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CD300E		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CD300E
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for CD300E		OriGene Custom Protein Services for CD300E
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CD300E
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD300E
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD300E
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD300E
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD300E
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD300E

	GenScript Custom Purified and Recombinant Proteins Services for CD300E		GenScript cDNA clones with any tag delivered in your preferred vector for CD300E
	GenScript Custom Assay Services for CD300E		GenScript Custom Superior Antibodies Services for CD300E
	GenScript Custom overexpressing Cell Line Services for CD300E		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	Regulatory tfbs in CD300E promoter
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	Browse Sino Biological Proteins and Antibodies
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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	Antibodies for CD300E
	See all of Abcam's Antibodies, Kits and Proteins for CD300E
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Browse ProSpec Recombinant Proteins

CD300E Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for CD300E

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD300E

	Browse SwitchGear 3'UTR luciferase reporter plasmids for CD300E
	SwitchGear Promoter luciferase reporter plasmids for CD300E

Search ThermoFisher Antibodies for CD300E

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD300E

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CD300E

Sirion Biotech Customized:

	stable knockdown cell line services for CD300E
	inducible knockdown cell line services for CD300E
	design and validation of potent shRNA sequences against CD300E
	adenovirus for potent knockdown of CD300E
	adenovirus for overexpression of CD300E
	stable overexpressing cell line services for CD300E
	inducible overexpressing cell line services for CD300E

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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CD300E Gene

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Export list of displayed genes

CD300E Gene

CD300e molecule

Aliasesfor CD300E gene

Summariesfor CD300E gene

Genomic Viewsfor CD300E gene

Proteinsfor CD300E gene

Protein Domains /Familiesfor CD300E gene

Functionfor CD300E gene

Pathways & Interactionsfor CD300E gene

Drugs & Compoundsfor CD300E gene

Transcriptsfor CD300E gene

Expression for CD300E gene

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Disorders / Diseasesfor CD300E gene

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External Searches for CD300E gene

Genome Databases showing CD300E gene

Other Databases showing CD300E gene

Specialized Databases showing CD300E gene

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Aliases
for CD300E gene

Summaries
for CD300E gene

Genomic Views
for CD300E gene

Proteins
for CD300E gene

Protein Domains /
Families
for CD300E gene

Function
for CD300E gene

Pathways & Interactions
for CD300E gene

Drugs & Compounds
for CD300E gene

Transcripts
for CD300E gene

Expression
for CD300E gene

Orthologs
for CD300E gene

Paralogs
for CD300E gene

Genomic Variants
for CD300E gene

Disorders / Diseases
for CD300E gene

Publications
for CD300E gene

Intellectual Property
for CD300E gene

Products
for CD300E gene