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CD300E Gene

protein-coding   GIFtS: 49
GCID: GC17M072606

CD300e Molecule

(Previous names: CD300 antigen like family member E, CD300e antigen)
(Previous symbol: CD300LE)
  See CD300E-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD300e Molecule1 2     CLM-22 3
CD300LE1 2 3 5     CMRF35-A52 3
CD300e Antigen1 2 3     IREM-22 3
CLM22 3 5     PIgR-22 3
IREM22 3 5     PIgR22 3
CD300 Antigen Like Family Member E1 2     CD300 Antigen-Like Family Member E2 3
Immune Receptor Expressed On Myeloid Cells 22 3     CMRF35-Like Molecule 22
Poly-Ig Receptor 22 3     CMRF35A53
Polymeric Immunoglobulin Receptor 22 3     

External Ids:    HGNC: 288741   Entrez Gene: 3425102   Ensembl: ENSG000001864077   OMIM: 6098015   UniProtKB: Q496F63   

Export aliases for CD300E gene to outside databases

Previous GC identifers: GC17M070119 GC17M068017


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CD300E Gene:
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells.
The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an
activating receptor. (provided by RefSeq, Nov 2012)

GeneCards Summary for CD300E Gene:
CD300E (CD300e molecule) is a protein-coding gene. Diseases associated with CD300E include lice infestation, and tungiasis. An important paralog of this gene is CD300LG.

UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6
Function: Probably acts as an activating receptor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD300E gene promoter:
         TBP   USF1   NRSF form 1   USF2   USF-1:USF-2   NRSF form 2   E47   TFIID   USF-1   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD300E promoter sequence
   Search Chromatin IP Primers for CD300E

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD300E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

CD300E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD300E gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M072606:  view genomic region     (about GC identifiers)

Start:
72,606,022 bp from pter      End:
72,619,897 bp from pter
Size:
13,876 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6 (See protein sequence)
Recommended Name: CMRF35-like molecule 2 precursor  
Size: 205 amino acids; 22918 Da
Subunit: Interacts with TYROBP
Secondary accessions: B4DNS1 Q7Z7I3

Explore the universe of human proteins at neXtProt for CD300E: NX_Q496F6

Explore proteomics data for CD300E at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn154

  • See CD300E Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_852114.2  
    ENSEMBL proteins: 
     ENSP00000376395   ENSP00000415488   ENSP00000416642   ENSP00000329942  
    Reactome Protein details: Q496F6

    CD300E Human Recombinant Protein Products:

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    Novus Biologicals CD300E Proteins
    Novus Biologicals CD300E Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CD300E 

    CD300E Antibody Products:

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    LSBio Antibodies in human, mouse, rat for CD300E

    CD300E Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for CD300E 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q496F6

    ProtoNet protein and cluster: Q496F6

    UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6
    Similarity: Belongs to the CD300 family
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    Find genes that share domains with CD300E           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLM2_HUMAN, Q496F6
    Function: Probably acts as an activating receptor

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CD300E           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD300E
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD300E
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    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate CD300E:
    hsa-miR-622 hsa-miR-1205
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CD300E

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    Clone
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    Sino Biological Human cDNA Clone for CD300E
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CLM2_HUMAN, Q496F6: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with CD300E           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CD300E About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling by FGFR
    DAP12 interactions0.89


    Find genes that share SuperPaths with CD300E           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for CD300E
        DAP12 interactions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CD300E
    Interactions:

        Search GeneGlobe Interaction Network for CD300E

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CD300E (ENSP000003299424) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TYROBPENSP000002626294STRING: ENSP00000262629
    CD8BENSP000003311724STRING: ENSP00000331172
    --ENSP000003935494STRING: ENSP00000393549
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045087innate immune response TAS--

    Find genes that share ontologies with CD300E           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CD300E (CLM2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CD300E gene: 
    NM_181449.2  

    Unigene Cluster for CD300E:

    CD300e molecule
    Hs.158954  [show with all ESTs]
    Unigene Representative Sequence: BX648376
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392619(uc002jlb.2) ENST00000412268 ENST00000426295 ENST00000328630

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CD300E using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CD300E:
    hsa-miR-622 hsa-miR-1205
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CD300E
    Predesigned siRNA for gene silencing in human, mouse, rat CD300E
    Clone
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    OriGene clones in human, mouse for CD300E (see all 6)
    OriGene ORF clones in mouse, rat for CD300E
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CD300E (NM_181449)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD300E
    Primer
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    OriGene qPCR primer pairs and template standards for CD300E
    OriGene qSTAR qPCR primer pairs in human, mouse for CD300E
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD300E
      QuantiTect SYBR Green Assays in human, mouse, rat CD300E
      QuantiFast Probe-based Assays in human, mouse, rat CD300E

    Additional mRNA sequence: 

    AF395839.1 AK298031.1 AK303545.1 BC100888.1 BC100889.1 BC100890.1 BX648376.1 

    1 DOTS entry:

    DT.75161866 

    17 AceView cDNA sequences:

    BM993876 CN479411 BX648376 BV194694 CA449920 NM_181449 BX112992 BU681667 
    AL598315 AF395839 AI380107 BX478972 AI889065 CB528671 BF359799 BI060884 
    BI061023 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CD300E expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTGAATTT
    CD300E Expression
    About this image

    CD300E Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CD300E Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.158954

    UniProtKB/Swiss-Prot: CLM2_HUMAN, Q496F6
    Tissue specificity: Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at
    protein level)

        Custom PCR Arrays for CD300E
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD300E

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CD300E gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cd300e1 , 5 CD300e antigen1, 5 71.65(n)1
    60.92(a)1
      11 (80.58 cM)5
    2173061  NM_172050.21  NP_742047.11 
     1150519175 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    26(a)
    1 → many
    18(10693051-10694640)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    36(a)
    27(a)
    many ↔ many
    many ↔ many
    2(116020650-116030691)
    2(115986797-115996463)


    ENSEMBL Gene Tree for CD300E (if available)
    TreeFam Gene Tree for CD300E (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CD300E gene
    CD300LG2  CD300A2  CD300LB2  CD300C2  CD300LF2  CD300LD2  
    7 SIMAP similar genes for CD300E using alignment to 4 protein entries:     CLM2_HUMAN (see all proteins):
    CD300C    CD300LB    CD300LD    ADORA3    CD300LF    CD300LG
    CD300A

    Find genes that share paralogs with CD300E           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CD300E (see all 420)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0391304
    A colorectal cancer sample4--see VAR_0391302 T A mis40--------
    rs1476191951,2
    --72605537(+) TTTGCA/GATGTT 1 -- ds50010--------
    rs1890568961,2
    --72605927(+) GCATCA/GCTATT 1 -- ds50010--------
    rs1163417781,2
    C,F--72605949(+) TCTTAG/AACTTC 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1421416211,2
    --72606024(+) CCATAG/TACACA 1 -- ut310--------
    rs795641851,2
    C,F--72606090(+) AGGGGA/GAAAAA 1 -- ut311Minor allele frequency- G:0.10EA 120
    rs3746492571,2
    C--72606090(+) TAGGG-/AAAAAA 1 -- ut310--------
    rs1154725851,2
    C,F--72606189(+) TCTTAA/CCTCTT 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs1445213301,2
    C--72606255(+) GTGACC/TTTGTG 1 -- ut310--------
    rs1809067881,2
    C--72606293(+) ATCCCA/GGTCCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CD300E (72606022 - 72619897 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CD300E:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2604772CNV Insertion19546169
    esv33995CNV Loss17666407
    esv2751770CNV Gain17911159
    dgv372n27CNV Gain19166990
    nsv517569CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CD300E
    DNA2.0 Custom Variant and Variant Library Synthesis for CD300E

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609801    OMIM disorders: --

    3 diseases for CD300E:    
    About MalaCards
    lice infestation    tungiasis    scabies

    3 diseases from the University of Copenhagen DISEASES database for CD300E:
    Tungiasis     Scabies     Lice infestation

    Find genes that share disorders with CD300E           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: CD300E (1 document)

    Export disorders for CD300E gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CD300E gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with CD300E)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of a novel immune receptor restricted to the monocytic lineage. (PubMed id 15557162)1, 2, 3 Aguilar H.... Lopez-Botet M. (J. Immunol. 2004)
    2. IREM-1 is a novel inhibitory receptor expressed by myeloid cells. (PubMed id 15549731)1, 3 Alvarez-Errico D....Lopez-Botet M. (Eur. J. Immunol. 2004)
    3. CD300 molecule regulation of human dendritic cell functions. (PubMed id 23072861)1 Gasiorowski R.E....Clark G.J. (Immunol. Lett. 2013)
    4. Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. (PubMed id 20039296)1 Brckalo T....LA^pez-Botet M. (Eur. J. Immunol. 2010)
    5. Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. (PubMed id 20200953)1 Karasik D....Demissie S. (J. Bone Miner. Res. 2010)
    6. The CD300 molecules regulate monocyte and dendritic cell functions. (PubMed id 19592130)1 Clark G.J....Hart D.N. (Immunobiology 2009)
    7. The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions. (PubMed id 19359216)1 Clark G.J....Hart D.N. (Trends Immunol. 2009)
    8. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    9. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 342510 HGNC: 28874 AceView: IREM2 Ensembl:ENSG00000186407 euGenes: HUgn342510
    ECgene: CD300E H-InvDB: CD300E

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CD300E Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CD300E gene:
    Search GeneIP for patents involving CD300E

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     EMD Millipore genomic analysis products

      
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     Block miRNA regulation of human, mouse, rat CD300E using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CD300E
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     QuantiFast Probe-based Assays in human, mouse, rat CD300E QuantiTect SYBR Green Assays in human, mouse, rat CD300E
     Custom PCR Arrays for CD300E Search Chromatin IP Primers for CD300E
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CD300E  Search GeneGlobe Interaction Network for CD300E
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     Search Tocris compounds for CD300E (CLM2)
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     Browse ESI BIO Cell Lines and PureStem Progenitors for CD300E
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     Search Addgene for plasmids for CD300E
      Search eBioscience for proteins for CD300E
      Search eBioscience for elisas for CD300E
      eBioscience FlowRNA Probe Sets
           
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