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CD24 Gene

protein-coding   GIFtS: 53
GCID: GC06U900001

CD24 Molecule

(Previous name: CD24 antigen (small cell lung carcinoma cluster 4 antigen))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CD24 Molecule1 2
CD24 Antigen (Small Cell Lung Carcinoma Cluster 4 Antigen)1 2
CD24A2 3
Signal Transducer CD242
CD24 Antigen3
Small Cell Lung Carcinoma Cluster 4 Antigen3

External Ids:    HGNC: 16451   Entrez Gene: 1001339412   OMIM: 6000745   UniProtKB: P250633   

Export aliases for CD24 gene to outside databases

Previous GC identifers: GC0YM020359 GC0YM020047 GC0YM019540 GC0YM019611 GC0YM021152


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CD24 Gene:
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded
protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. (provided by RefSeq, Jul
2008)

GeneCards Summary for CD24 Gene:
CD24 (CD24 molecule) is a protein-coding gene. Diseases associated with CD24 include adult mesoblastic nephroma, and bladder lymphoma. GO annotations related to this gene include protein tyrosine kinase activator activity and protein kinase binding.

UniProtKB/Swiss-Prot: CD24_HUMAN, P25063
Function: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like
ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming
cells

Gene Wiki entry for CD24 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_025741.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CD24 gene promoter:
         Nkx3-1   Max1   Nkx3-1 v1   POU3F2   Nkx3-1 v2   SRY   FOXC1   Nkx3-1 v3   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD24 promoter sequence
   Search Chromatin IP Primers for CD24

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CD24


Genomic Location:
Chromosome:6   

Entrez Gene cytogenetic band: 6q21   HGNC cytogenetic band: 6q21

GeneLoc information about chromosome 6        


(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CD24_HUMAN, P25063 (See protein sequence)
Recommended Name: Signal transducer CD24 precursor  
Size: 80 amino acids; 8097 Da
Subunit: Interacts with LYN and FGR in a cell-type specific manner. Binds FRG in a small cell cancer line, LYN in
the erythroleukemia cell line K-562 and in Burkitt's lymphoma
Sequence caution: Sequence=AAD14170.1; Type=Erroneous initiation;
Secondary accessions: Q16257 Q53XS0

Explore the universe of human proteins at neXtProt for CD24: NX_P25063

Post-translational modifications: 

  • Extensively O-glycosylated1
  • Glycosylation2 at Asn36, Asn52
  • REFSEQ proteins: NP_037362.1  Reactome Protein details: P25063

    CD24 Human Recombinant Protein Products:

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    R&D Systems Recombinant & Natural Proteins for CD24
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    OriGene Custom MassSpec
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    Novus Biologicals CD24 Proteins
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    Sino Biological Cell Lysate for CD24
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    Cloud-Clone Corp. Proteins for CD24

    CD24 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of CD24
    R&D Systems Antibodies for CD24
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    Novus Biologicals CD24 Antibodies
    Abcam antibodies for CD24
    Cloud-Clone Corp. Antibodies for CD24
    ThermoFisher Antibody for CD24
    LSBio Antibodies in human, mouse, rat for CD24

    CD24 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CD24
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CD24
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CD24
    Cloud-Clone Corp. CLIAs for CD24


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules

    1 InterPro protein domain:
     IPR028029 CD24

    Graphical View of Domain Structure for InterPro Entry P25063

    ProtoNet protein and cluster: P25063

    UniProtKB/Swiss-Prot: CD24_HUMAN, P25063
    Similarity: Belongs to the CD24 family


    CD24 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CD24_HUMAN, P25063
    Function: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like
    ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
    Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming
    cells
    Induction: Expression is lost when primary B-cells are induced to differentiate in antibody-forming cells

         Genatlas biochemistry entry for CD24:
    cell differentiation antigen CD24,glycosyl phosphatidylinositol (GPI) linked membrane sialoglycoprotein,identified
    by monoclonal antibodies BA-1,VIB-E3,expressed on granulocyte,B lymphocyte,brain,kidney,regenerating muscle,(?
    involved in signal transduction),with cell-type specific promoter activity in small cell lung cancer

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity NAS8213086
    GO:0005515protein binding IPI15633604
    GO:0019901protein kinase binding IPI8753773
    GO:0030296protein tyrosine kinase activator activity IDA11313396
         
    CD24 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cd24a):
     hematopoietic system  immune system  reproductive system 

    CD24 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cd24atm1Pjln for CD24

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CD24
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CD24

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD24
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD24

    miRNA
    Products:
        
    miRTarBase miRNAs that target CD24:
    hsa-mir-373-3p (MIRT002501)

    Block miRNA regulation of human, mouse, rat CD24 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD24 (see all 15):
    hsa-miR-3163 hsa-miR-4317 hsa-miR-26a-2* hsa-miR-561 hsa-miR-627 hsa-miR-551b* hsa-miR-587 hsa-miR-582-5p
    SwitchGear 3'UTR luciferase reporter plasmidCD24 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CD24
    Predesigned siRNA for gene silencing in human, mouse, rat CD24

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CD24

    Clone
    Products:
         
    OriGene clones in human, mouse for CD24 (see all 5)
    OriGene ORF clones in mouse, rat for CD24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CD24 (NM_198053)
    Sino Biological Human cDNA Clone for CD24
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD24

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CD24
    ESI BIO PureStem Progenitors for CD24: 
    PureStem 4D20.8, NCr-fac Progenitor, PureStem MEL2, NCr-fac Progenitor
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD24


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CD24_HUMAN, P25063: Cell membrane; Lipid-anchor, GPI-anchor
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular3
    cytoskeleton2
    nucleus2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0009986cell surface IDA16532032
    GO:0016020membrane IDA10037815
    GO:0031225anchored component of membrane IEA--
    GO:0045121membrane raft IDA11313396

    CD24 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CD24 About    
    See pathways by source

    SuperPathContained pathways About
    1Hematopoietic cell lineage
    Hematopoietic cell lineage

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for CD24
        L1CAM interactions


    1 Kegg Pathway  (Kegg details for CD24):
        Hematopoietic cell lineage


    CD24 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including CD24: 
              Nephrotoxicity in human mouse rat
              Cell Surface Markers in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CD24

    Selected Interacting proteins for CD24 (P250631, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LYNP079481, 3EBI-6267018,EBI-79452 I2D: score=2 
    FGRP097693I2D: score=2 
    SELPP161093I2D: score=2 
    HMGB1P094293I2D: score=1 
    SIGLEC10Q96LC73I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 27):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEP15174142
    GO:0001775cell activation IDA8223854
    GO:0001959regulation of cytokine-mediated signaling pathway ISS16390867
    GO:0002237response to molecule of bacterial origin ISS15493995
    GO:0002768immune response-regulating cell surface receptor signaling pathway IC11313396

    CD24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CD24



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CD24 gene: 
    NM_013230.2  

    Unigene Cluster for CD24:

    CD24 molecule
    Hs.644105  [show with all ESTs]
    Unigene Representative Sequence: AK125531
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CD24 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CD24 (see all 15):
    hsa-miR-3163 hsa-miR-4317 hsa-miR-26a-2* hsa-miR-561 hsa-miR-627 hsa-miR-551b* hsa-miR-587 hsa-miR-582-5p
    SwitchGear 3'UTR luciferase reporter plasmidCD24 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CD24
    Predesigned siRNA for gene silencing in human, mouse, rat CD24
    Clone
    Products:
         
    OriGene clones in human, mouse for CD24 (see all 5)
    OriGene ORF clones in mouse, rat for CD24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CD24 (NM_198053)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD24
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CD24
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CD24
      QuantiTect SYBR Green Assays in human, mouse, rat CD24
      QuantiFast Probe-based Assays in human, mouse, rat CD24

    Additional mRNA sequence: 

    AK026603.1 AK125531.1 BC064619.1 BT007404.1 D87667.1 DQ530230.1 DQ530231.1 DQ530232.1 
    DQ530233.1 DQ530234.1 L33930.1 M58664.1 S75311.1 X69397.1 

    Selected DOTS entries (see all 53):

    DT.100882108  DT.95085902  DT.100882117  DT.87078331  DT.95195116  DT.95195104  DT.95116257  DT.100882100 
    DT.86838563  DT.100882122  DT.120651633  DT.120651656  DT.92466399  DT.100882127  DT.120651710  DT.120651704 
    DT.120651787  DT.102843352  DT.100882099  DT.100882107  DT.100882121  DT.100882132  DT.120651680  DT.95194960 

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CD24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAACAAACA
    CD24 Expression
    About this image


    CD24 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 20) fully expand
     
     Kidney (Urinary System)    fully expand to see all 6 entries
             Presumptive Podocytes Podocyte Layer
             Adult human kidney epithelial cells
             Podocalyxin+, CD24+, GCTM2-
     
     Blood (Cardiovascular System)    fully expand to see all 6 entries
             Immature B-Cells Peripheral Blood
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 7 entries
             hIPS1
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Adult Dopaminergic Neurons Substantia Nigra pars Compacta
             Human neural stem cells (HuCNS-SCŪ)
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Stem Cells Subcutaneous White Adipose
    CD24 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.644105

    UniProtKB/Swiss-Prot: CD24_HUMAN, P25063
    Tissue specificity: B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in
    erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells

        Pathway & Disease-focused RT2 Profiler PCR Arrays including CD24: 
              Nephrotoxicity in human mouse rat
              Cell Surface Markers in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CD24
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CD24
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    QuantiFast Probe-based Assays in human, mouse, rat CD24
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CD24 gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cd24a5 CD24a antigen   --   10 (23.01 cM) 43579169 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    2 SNPs for CD24    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104654601,2,4
    ----see VAR_0315762 mis40--------
    rs87341,2,4
    ----see VAR_0161562 mis40--------
    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CD24:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1565023CNV Insertion17803354
    nsv10025CNV Gain18304495

    Human Gene Mutation Database (HGMD): CD24
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CD24
    DNA2.0 Custom Variant and Variant Library Synthesis for CD24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600074    OMIM disorders: --

    UniProtKB/Swiss-Prot: CD24_HUMAN, P25063
  • Multiple sclerosis (MS) [MIM:126200]: A multifactorial, inflammatory, demyelinating disease of the
    central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and
    lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological
    mechanism is regarded as an autoimmune attack of the myelin sheath, mediated by both cellular and humoral
    immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of
    sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors
    influence susceptibility to the disease. Note=Disease susceptibility may be associated with variations affecting
    the gene represented in this entry

  • Selected diseases for CD24 (see all 59):    
    About MalaCards
    adult mesoblastic nephroma    bladder lymphoma    mesoblastic nephroma    paresthesia
    pterygium    ductal carcinoma in situ    common variable immunodeficiency    noma
    relapsing-remitting multiple sclerosis    hepatitis b virus infection    clear cell renal cell carcinoma    malignant mesothelioma
    multiple sclerosis    pancreatic ductal adenocarcinoma    burkitt's lymphoma    renal cell carcinoma
    hepatitis b    sarcoidosis    laryngeal squamous cell carcinoma    spasticity

    2 diseases from the University of Copenhagen DISEASES database for CD24:
    Breast cancer     Leukemia

    CD24 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CD24
    Human Genome Epidemiology (HuGE) Navigator: CD24 (12 documents)

    Export disorders for CD24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CD24 gene, integrated from 10 sources (see all 164):
    (articles sorted by number of sources associating them with CD24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CD24 is a genetic modifier for risk and progression of multiple sclerosis. (PubMed id 14657362)1, 2, 4 Zhou Q.... Liu Y. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    2. Mapping of CD24 and homologous sequences to multiple chromosomal loci. (PubMed id 7959762)1, 2, 3 Hough M.R.... Humphries R.K. (Genomics 1994)
    3. CD24 gene exon 2 dimorphism does not affect disease susceptibility in Japanese sarcoidosis patients. (PubMed id 21086907)1, 4 Tanizawda K....Mishima M. (Sarcoidosis Vasc Diffuse Lung Dis 2010)
    4. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    5. Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis. (PubMed id 20378664)1, 4 Sombekke M.H....Uitdehaag B.M. (Mult. Scler. 2010)
    6. CD24 Ala57Val gene polymorphism and the risk of systemic lupus erythematosus. (PubMed id 20230526)1, 4 Piotrowski P....JagodziA8ski P.P. (Tissue Antigens 2010)
    7. CD24 gene polymorphism is associated with the disease progression and susceptibility to multiple sclerosis in the Iranian population. (PubMed id 19896210)1, 4 Ronaghi M....Etemadifar M. (Psychiatry Res 2009)
    8. Association of CD24 gene polymorphisms with susceptibility to biopsy-proven giant cell arteritis. (PubMed id 18381780)1, 4 Rueda B....Gonzalez-Gay M.A. (J. Rheumatol. 2008)
    9. A dinucleotide deletion in CD24 confers protection against autoimmune diseases. (PubMed id 17411341)1, 4 Wang L.... Liu Y. (PLoS Genet. 2007)
    10. Association of a CD24 gene polymorphism with susceptibility to systemic lupus erythematosus. (PubMed id 17763438)1, 4 SA!nchez E....MartA-n J. (Arthritis Rheum. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 100133941 HGNC: 1645 euGenes: HUgn100133941 ECgene: CD24
    Kegg: 100133941 H-InvDB: CD24

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CD24 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CD24 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CD24 gene:
    Search GeneIP for patents involving CD24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse Small Molecules at EMD Millipore
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     PureStem Progenitors for CD24: PureStem 4D20.8, NCr-fac Progenitor, PureStem MEL2, NCr-fac Progenitor
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