Aliases for CD24 Gene
External Ids for CD24 Gene
Previous GeneCards Identifiers for CD24 Gene
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
GeneCards Summary for CD24 Gene
CD24 (CD24 Molecule) is a Protein Coding gene. Diseases associated with CD24 include demyelinating disease. Among its related pathways are Developmental Biology and L1CAM interactions. GO annotations related to this gene include protein kinase binding and carbohydrate binding.
UniProtKB/Swiss-Prot for CD24 Gene
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.