Aliases for CD1D Gene
External Ids for CD1D Gene
Previous GeneCards Identifiers for CD1D Gene
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD1D Gene
CD1D (CD1d Molecule) is a Protein Coding gene. Diseases associated with CD1D include mycobacterium malmoense and breast angiosarcoma. Among its related pathways are Amoebiasis and TNF Signaling (sino). GO annotations related to this gene include receptor activity and cell adhesion molecule binding. An important paralog of this gene is CD1C.
UniProtKB/Swiss-Prot for CD1D Gene
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.