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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CD1C Gene

protein-coding GIFtS: 53
GCID: GC01P158259

CD1c molecule

(Previous names: CD1C antigen, c polypeptide, CD1c antigen )
(Previous symbol: CD1)

Explore 24 diseases affiliated with
CD1C via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CD1c Molecule¹ ²		CD1A²
CD1¹ ²		R7²
CD1C Antigen, C Polypeptide¹ ²		Cortical Thymocyte Antigen CD1C²
CD1c Antigen¹ ³		Differentiation Antigen CD1-Alpha-3²
BDCA1²		T-Cell Surface Glycoprotein CD1c²

External Ids:	HGNC: 1636¹	Entrez Gene: 911²	Ensembl: ENSG00000158481⁷	OMIM: 188340⁵	UniProtKB: P29017³

Export aliases for CD1C gene to outside databases

Previous GC identifers: GC01P156052 GC01P153993 GC01P155037 GC01P155476 GC01P155072 GC01P156526 GC01P129617

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD1C:

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the

major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins

mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human

genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to

differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene

is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail.

Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CD1C_HUMAN, P29017

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to

T-cell receptors on natural killer T-cells

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CD1C gene promoter:
Bach1 AP-1 LCR-F1 Evi-1 MEF-2A S8 Chx10 aMEF-2 Pax-4a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for CD1C

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD1C

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q23 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q22-q23

CD1C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD1C gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P158259: view genomic region (about GC identifiers)

Start:	158,259,563 bp from pter	End:	158,264,564 bp from pter
Size:	5,002 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CD1C_HUMAN, P29017 (See protein sequence)

Recommended Name: T-cell surface glycoprotein CD1c precursor

Size: 333 amino acids; 37654 Da

Subunit: Heterodimer with B2M (beta-2-microglobulin)

Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to

intracellular trafficking between the cell membrane and endosomes

Miscellaneous: During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by

lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes, before

trafficking back to the cell surface

1 PDB 3D structure from and Proteopedia for CD1C:

3OV6 (3D)

Secondary accessions: Q5TDJ7 Q6IAS4 Q9UMM0 Q9UN96

Explore the universe of human proteins at neXtProt for CD1C: NX_P29017

CD1C Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001756.2

ENSEMBL proteins:

ENSP00000357152 ENSP00000408755

Human Recombinant Protein Products:

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	Browse Proteins at Uscn

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	2701945
GO:0005887	integral to plasma membrane	TAS	1702817
GO:0010008	endosome membrane	IEA	--
GO:0016020	membrane	--	--

CD1C for ontologies About GeneDecksing

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CD1C for domains About GeneDecksing

5 InterPro domains/families:

IPR011162 MHC_I/II-like_Ag-recog

IPR013783 Ig-like_fold

IPR003597 Ig_C1-set

IPR007110 Ig-like_dom

IPR011161 MHC_I-like_Ag-recog

Graphical View of Domain Structure for InterPro Entry P29017

ProtoNet protein and cluster: P29017

1 Blocks protein family: IPB003597 Immunoglobulin C-type

UniProtKB/Swiss-Prot: CD1C_HUMAN, P29017

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CD1C_HUMAN, P29017

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to

T-cell receptors on natural killer T-cells

Genatlas biochemistry entry for CD1C:

cell differentiation antigen CD1C,43kDa,membrane glycoprotein,B2M associated,identified by monoclonal antibodies

L161,7C6,PHM3 (see CD1@)

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		1 QIAGEN miScript miRNA Assays for microRNA that regulate CD1C:
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD1C

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030883	endogenous lipid antigen binding	IDA	--
GO:0030884	exogenous lipid antigen binding	IDA	--
GO:0051861	glycolipid binding	IDA	--
GO:0071723	lipopeptide binding	IDA	--

CD1C for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for CD1C:

Increased G1 DNA content

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Hematopoietic cell lineage

Hematopoietic cell lineage

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for CD1C):

Hematopoietic cell lineage

CD1C for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CD1C

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002286	T cell activation involved in immune response	IDA	--
GO:0006955	immune response	--	--
GO:0019882	antigen processing and presentation	IEA	--

CD1C for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CD1C for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CD1C

10/519 HMDB Compounds for CD1C (see all 519) About this table

Compound	Synonyms	CAS #	PubMed Ids
3-Dehydrosphinganine	1-Hydroxy-2-amino-3-oxo-octadecane (see all 9)	16105-69-4	--
3-O-Sulfogalactosylceramide (d18:1/12:0)	Sulfatide (d18:1/12:0) (see all 13)	852100-88-0	--
3-O-Sulfogalactosylceramide (d18:1/14:0)	Sulfatide (d18:1/14:0) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/16:0)	Sulfatide (d18:1/16:0) (see all 13)	862509-48-6	--
3-O-Sulfogalactosylceramide (d18:1/18:0)	Sulfatide (d18:1/18:0) (see all 13)	244215-65-4	--
3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))	Sulfatide (d18:1/18:1(9Z)) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/20:0)	Sulfatide (d18:1/20:0) (see all 13)	265096-81-9	--
3-O-Sulfogalactosylceramide (d18:1/22:0)	Sulfatide (d18:1/22:0) (see all 13)	265096-83-1	--
3-O-Sulfogalactosylceramide (d18:1/24:0)	Sulfatide (d18:1/24:0) (see all 16)	151122-71-3	--
3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))	Sulfatide (d18:1/24:1(15Z)) (see all 13)	151057-28-2	--

2 Novoseek chemical compound relationships for CD1C gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
glycolipid	71.4	8	9820479 (1), 12391186 (1), 15185366 (1), 15493902 (1) (see all 6)
lipid	53.1	52	11145857 (3), 19374905 (3), 14551186 (3), 10899914 (3) (see all 25)

Search CenterWatch for drugs/clinical trials and news about CD1C

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CD1C gene:

NM_001765.2

Unigene Cluster for CD1C:

CD1c molecule

Hs.132448 [show with all ESTs]

Unigene Representative Sequence: NM_001765

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000368170(uc001fru.3 uc021pbl.1) ENST00000443761

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD1C
		1 QIAGEN miScript miRNA Assays for microRNA that regulate CD1C:
		hsa-miR-550a
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD1C
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD1C

Additional cDNA sequence:

AK226024.1 AK298234.1 AK310577.1 AK310710.1 BC126465.1 BC126467.1 CR457080.1 M28827.1

X79311.1

7 DOTS entries:

DT.211442 DT.121377686 DT.75102006 DT.121377698 DT.92418900 DT.95158096 DT.121377680

24/55 AceView cDNA sequences (see all 55):

AV714702 M28827 CB162552 BU682739 AI707712 CB161588 BQ006118 CA436720

BP340167 NM_001765 AA380406 X79311 AV715961 CR615066 AA769104 BX116983

AI735106 AI523463 T28587 BM804892 BX401817 AW574786 AI673412 BI772670

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CD1C About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6	^	7
SP1:			-				-
SP2:															-
SP3:

ECgene alternative splicing isoforms for CD1C

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CD1C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

CD1C expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CD1C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CD1C

SOURCE GeneReport for Unigene cluster: Hs.132448

UniProtKB/Swiss-Prot: CD1C_HUMAN, P29017

Tissue specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues

SABiosciences Expression via Pathway-Focused PCR Arrays including CD1C:

Cell Surface Markers in human mouse rat

Antigen Presenting Cells in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CD1C gene from 3/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GGA.29894⁶	Uncharacterized protein	22(a)	1 → many	16(1371-11718)
lizard (Anolis carolinensis)	Reptilia	--	--	25(a)	1 → many	2(189406880-189414378)
zebrafish (Danio rerio)	Actinopterygii	BX572619.3⁶ CR339041.2⁶ (see all 16)	--	19(a) 18(a) (see all 16)	many ↔ many many ↔ many (see all 16)	25(11071636-11074578) 25(11250338-11263782)

ENSEMBL Gene Tree for CD1C (if available)
TreeFam Gene Tree for CD1C (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CD1C gene

CD1A² CD1D² CD1B² CD1E²

17 SIMAP similar genes for CD1C using alignment to 2 protein entries: CD1C_HUMAN (see all proteins):

CDIE CD1b CD1B CD1A CD1E CD1D

HLA-DQB1 HLA-DRB1 HLA-DRB4 HLA DRB4 HLA-DRB4*0102 MICA

HFE HLA-DRB5 HLA HLA-A HLA-DMB

CD1C for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs118119500^1,2	F,	--	158257730(+)	`CAGGAC/TTGGAG`	1	--	us2k¹		1		EA	120
rs10797006^1,2	C,F,A,H,	--	158257838(+)	`TAGGAA/CCATGG`	1	--	us2k¹		24		NS EA NA WA CSA	2508
rs181037996^1,2		--	158257931(+)	`AAGATG/TAGCAA`	1	--	us2k¹		0	--	--	--	--
rs6689983^1,2	C,F,	--	158257979(+)	`TTTGAA/CCTGGG`	1	--	us2k¹		1		WA	118
rs149323392^1,2		--	158258121(+)	`AAGTAC/TCATGT`	1	--	us2k¹		0	--	--	--	--
rs144255468^1,2	C,	--	158258140(+)	`GTAAAC/TACATA`	1	--	us2k¹		0	--	--	--	--
rs17273762^1,2	C,F,H,	--	158258188(+)	`ATGGGA/GTTTTC`	1	--	us2k¹ tfbs³		10		NA NS EA WA CSA	676
rs148301838^1,2		--	158258276(+)	`TTCAGG/TGCTCA`	1	--	us2k¹		0	--	--	--	--
rs141390635^1,2		--	158258341(+)	`CACATA/TTGGCC`	1	--	us2k¹		0	--	--	--	--
rs114332221^1,2		--	158258350(+)	`CCAACT/CTTTTA`	1	--	us2k¹		1		WA	118

HapMap Linkage Disequilibrium report for CD1C (158259563 - 158264564 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CD1C: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD1C

DNA2.0 Custom Variant and Variant Library Synthesis for CD1C

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CD1C for disorders           About GeneDecksing

OMIM gene information: 188340    OMIM disorders: --

20/24 diseases for CD1C (see all 24):    About MalaCards

guillain-barre syndrome langerhans-cell histiocytosis mycobacterium malmoense bcg infection

mycosis fungoides histiocytosis sickle cell disease chronic lymphocytic leukemia

lymphocytic leukemia skin disease graves' disease periodontitis

periodontal disease hepatitis b pulmonary disease pertussis

leukemia t-cell leukemia tuberculosis psoriasis

6 Novoseek disease relationships for CD1C gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
autoimmunity	27.6	1	14734115 (1)
infectious disease	24.9	1	18989404 (1)
autoimmune diseases	23.5	5	18989404 (1), 15749918 (1), 12213347 (1)
skin diseases	6.57	1	11564162 (1)
tumors	0	6	18989404 (1), 19428084 (1), 12213347 (1), 14734115 (1)
tuberculosis	0	2	16034117 (2)

Genetic Association Database (GAD): CD1C
Human Genome Epidemiology (HuGE) Navigator: CD1C (4 documents)

Export disorders for CD1C gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CD1C gene, integrated from 9 sources (see all 103):
(articles sorted by number of sources associating them with CD1C)

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Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. (PubMed id 2447586)^{1, 2, 3} Martin L.H.... Milstein C. (1987)
Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. (PubMed id 10899914)^{1, 2, 9} Briken V.... Porcelli S.A. (2000)
CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. (PubMed id 10786796)^{1, 2, 9} Moody D.B....Porcelli S.A. (2000)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease. (PubMed id 11580851)^{1, 4} Jones D.C....Bunce M. (2001)
CD1c molecules broadly survey the endocytic system. (PubMed id 10890914)^{1, 2} Sugita M....Brenner M.B. (2000)
Polymorphism of human CD1 genes. (PubMed id 10488738)^{1, 2} Han M.... Robinson M.A. (1999)
Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts. (PubMed id 2701945)^{1, 2} Aruffo A. and Seed B. (1989)
Isolation of CD1 genes: a family of major histocompatibility complex- related differentiation antigens. (PubMed id 3097645)^{1, 2} Martin L.H.... Milstein C. (1986)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 911	HGNC: 1636	AceView: CD1C	Ensembl:ENSG00000158481	euGenes: HUgn911
ECgene: CD1C	Kegg: 911	H-InvDB: CD1C

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CD1C	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CD1C gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CD1C gene:
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