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CD1B Gene

protein-coding GIFtS: 60

GC01M156564

CD1b molecule
(Previous names: CD1B antigen, b polypeptide, CD1b antigen )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CD1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
CD1 ^²
CD1A ^²
MGC125990 ^²
MGC125991 ^²
OTTHUMP00000018908 ^²
R1 ^²

Descriptions
CD1B antigen, b polypeptide ^¹, ²
CD1b antigen ^¹, ², ³
CD1b molecule ^²
T-cell surface glycoprotein CD1b ^²
cortical thymocyte antigen CD1B ^²
differentiation antigen CD1-alpha-3 ^²

External Ids
HGNC: 1635¹
Entrez Gene: 910²
UniProtKB: P29016³
Ensembl: ENSG00000158485⁷

Search outside databases for aliases for CD1B gene

Previous GC identifers: GC01M156089 GC01M154030 GC01M155075 GC01M155514 GC01M155110

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CD1B:

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally

related to the major histocompatibility complex (MHC) proteins and form heterodimers with

beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid

antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes

organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their

cellular localization and specificity for particular lipid ligands. The protein encoded by this

gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail,

and requires vesicular acidification to bind lipid antigens. [provided by RefSeq]

UniProtKB/Swiss-Prot: CD1B_HUMAN, P29016

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and

presents them to T-cell receptors on natural killer T-cells

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CD1B gene

Entrez Gene cytogenetic band: 1q22-q23 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q22-q23

CD1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M156564: (about GC identifiers)

Start:	156,564,364 bp from pter
End:	156,567,945 bp from pter
Size:	3,582 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CD1B_HUMAN, P29016 (See protein sequence)

Recommended Name: T-cell surface glycoprotein CD1b precursor

Size: 333 amino acids; 36939 Da

Subunit: Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C

Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane.

Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes

and lysosomes. Localizes to cell surface lipid rafts

Miscellaneous: During protein synthesis and maturation, CD1 family members bind endogenous lipids

that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass

through endosomes or lysosomes, before trafficking back to the cell surface. Interaction with

saposin C is required for the loading of bacterial lipid antigens onto CD1B in the lysososme

Sequence caution: Sequence=CAI10852.1; Type=Erroneous gene model prediction;

PDB structures from and Proteopedia :

1GZP (3D)

1GZQ (3D)

1UQS (3D)

2H26 (3D)

Secondary accessions: Q5TDK9 Q5TDL0 Q9UMM2

Alternative splicing: 2 isoforms: P29016-1 P29016-2

REFSEQ proteins: NP_001755.1

ENSEMBL proteins:

ENSP00000357150

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD1, CD1b, CD1b+c)
	Human Recombinant Proteins from Abnova (CD1B)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005765	lysosomal membrane	IEA	--
GO:0005768	endosome	IEA	--
GO:0005886	plasma membrane	TAS	2447586 2701945
GO:0010008	endosome membrane	IEA	--
GO:0016021	integral to membrane	TAS	1702817

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Antibodies for CD1B:

	Invitrogen Antibodies for CD1B
	Millipore Mono- and Polyclonal Antibodies for the study of CD1B
	Sigma-Aldrich Antibodies for CD1B
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (CD1, CD1b, CD1b+c), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CD1B)
	Novus Biologicals Antibodies for CD1B

Assays for CD1B:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P29016

ProtoNet protein and cluster: P29016

1 Blocks protein family: IPB003597 Immunoglobulin C-type

UniProtKB/Swiss-Prot: CD1B_HUMAN, P29016

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD1B)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001764

Applied Biosystems Silencer® siRNAs for CD1B

Sigma-Aldrich siRNA and siRNA Panels for CD1B

Sigma-Aldrich shRNA for CD1B

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CD1B
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001764
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001764
untagged cDNA clone in CMV expression vector: NM_001764

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001764

UniProtKB/Swiss-Prot: CD1B_HUMAN, P29016

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and

presents them to T-cell receptors on natural killer T-cells

Genatlas biochemistry entry for CD1B:

cell differentiation antigen CD1B,45kDa,membrane glycoprotein,B2M associated,identified by

monoclonal antibodies WM-25,4A76,NUT2 (see CD1@)

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	12118248

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for CD1B (Your Favorite Gene powered by Ingenuity)

Lipid Antigen Presentation by CD1
Dendritic Cell Maturation

GeneDecks CD1B for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for CD1B

5 Interacting proteins for CD1B (ENSP00000357150³ P29016^{1, 2}) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B2M	P61769¹^,²	STRING (score=.99) EBI-1033762, EBI-714718 MINT-24761 EBI-1033762, EBI-714718 MINT-24761
B2M	P61769¹^,²	STRING (score=.99) EBI-1033762, EBI-714718 MINT-24761 EBI-1033762, EBI-714718 MINT-24761
HSPB1	ENSP00000248553³	STRING (score=.86)
CSF2	ENSP00000296871³	STRING (score=.728)
CD4	ENSP00000011653³	STRING (score=.72)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006955	immune response	IEA	--
GO:0019882	antigen processing and presentation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CD1B
2 Novoseek chemical compound relationships for CD1B gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glycolipid	75.36	6	14530337 (1), 11208113 (1), 18951873 (1), 9749821 (1) (see all 6)
lipid	56.33	28	11208113 (5), 16445682 (3), 14530337 (2), 14716313 (2) (see all 17)

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2 PharmGKB drug compound relationships for CD1B gene

Drug compound	PharmGKB Relations	PubMed IDs for articles supporting these relationships
mercaptopurine	PD FA GN	12704389
methotrexate	PD FA GN	12704389

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD1B)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001764

Sigma-Aldrich siRNA and siRNA Panels for CD1B

Sigma-Aldrich shRNA for CD1B

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001764

REFSEQ mRNAs for CD1B gene:

NM_001764.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001764

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001764
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001764
                                 untagged cDNA clone in CMV expression vector: NM_001764

Additional cDNA sequence:

AK303329.1 AK303330.1 AK310617.1 BC069481.1 BC074747.2 BC104216.1 BC104217.1 CR601779.1

M28826.1

6 DOTS entries:

DT.92037228 DT.100743997 DT.100847363 DT.121417044 DT.121417042 DT.95328694

22 AceView cDNA sequences:

BC069481 BC074747 CR601779 AA311900 BP368599 M28826 AW083073 BX094495

AW664772 BX457459 CD687240 AW104324 NM_001764 AI827808 AW027713 AI336342

AA927946 AW028156 BP367409 T28176 AA983871 BX437125

highest scoring ESTs for CD1B:

M28826 AA311900 BC069481 AA927946 AW027713 AW028156 BC074747 BP368599 BX094495 CD687240

Unigene Cluster for CD1B:

CD1b molecule

Hs.1310 [show with all ESTs]

Unigene Representative Sequence: AK310617

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CD1B

ExUns:	1	^	2	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7
SP1:			-
SP2:
SP3:

About this scheme

ECgene alternative splicing isoforms for CD1B

1 Ensembl transcript including schematic representation:

ENST00000368168

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CD1B expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CD1B

¹ / ² / ³

3 probe-sets matching CD1B gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34927_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M28826	1.00	1.00	1.00	1
206749_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001764	0.60	1.00	0.82	1
206749_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CD1B for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.1310
Expression variation in blood from EXPOLDB for CD1B
UniProtKB/Swiss-Prot: CD1B_HUMAN, P29016
Tissue specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various
other tissues

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CD1B gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	CD1B¹	--	CD1b molecule	99.3(n) 99.4(a)	457420 XM_513909.2 XP_513909.2
cow (Bos taurus)	LOC521663¹	--	similar to CD1b molecule	80.88(n) 76.69(a)	521663 XM_599931.3 XP_599931.2
chicken (Gallus gallus)	CD1B¹	--	CD1b molecule	44.63(n) 26.25(a)	425802 NM_001024582.1 NP_001019753.1

About this table Species with no ortholog for CD1B

ENSEMBL Gene Tree for CD1B

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CD1B gene

CD1A² CD1D² CD1C² CD1E²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/31 NCBI SNPs in CD1B are shown (see all 31 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 28)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs3176840^1,2	C,F,H,O	156568742(-)	`TGGCAA/CCTTAC`	1	--	ng3¹		8	NA EU EA WA	600
	rs3181082^1,2	C,F,H	156569117(-)	`AACCAG/ATAGTG`	1	--	ng3¹		5	NA EU EA WA	458
	rs16840096^1,2	C,F,H	156564584(+)	`ATTGAC/TTTTTG`	1	--	ut3¹ ese³		7	NA EU EA WA	560
	rs11583390^1,2	C,F,H	156564488(+)	`AAGTAC/ATTTTT`	1	--	ut3¹		8	EU EA WA	832
	rs3176847^1,2	F,H	156564319(-)	`TTTCTG/CCTTCT`	1	--	ng5¹		5	NA EU EA WA	458
	rs3181083^1,2	F,H	156569025(-)	`TACTCG/AGAATC`	1	--	ng3¹ tfbs³		5	NA EU EA WA	460
	rs12061967^1,2	F,H	156568823(+)	`CCACAT/AGTGGT`	1	--	ng3¹		4	EU EA WA	396
--	rs11806249^1,2	C,H	156565923(+)	`CCTAGC/TTGAGT`	1	Q/Q	syn¹ ese³		4	EU EA WA	416
	rs962879^1,2	A,C,F,H	156566930(+)	`GAGAAG/CTAAGG`	1	--	int¹		12	EA NA MN EU WA	842
--	rs3176842^1,2	C,F,H	156564981(-)	`gacagC/Ttctac`	1	--	int¹		5	NA EU EA WA	448

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HapMap Linkage Disequilibrium images for CD1B (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 188360

1 Novoseek disease relationship for CD1B gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tuberculosis	39.40	5	9749821 (1), 14716313 (1), 16034117 (1), 15365647 (1)

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1 PharmGKB disease relationship for CD1B gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	PD FA GN	12704389

About this table

Genetic Association Database: CD1B
Human Genome Epidemiology Navigator: CD1B (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/79 PubMed articles for CD1B gene (see all 79 ):

Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. (PubMed id 2447586)^{2, 3, 4} Martin L.H.... Milstein C. (1987)
Saposin C is required for lipid presentation by human CD1b. (PubMed id 14716313)^{1, 3, 4} Winau F....Schaible U.E. (2004)
Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. (PubMed id 10899914)^{1, 3, 4} Briken V.... Porcelli S.A. (2000)
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. (PubMed id 16874306)^{1, 3, 4} Garcia-Alles L.F.... Mourey L. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
The crystal structure of human CD1b with a bound bacterial glycolipid. (PubMed id 14764708)^{3, 4} Batuwangala T.... Jones E.Y. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. (PubMed id 12118248)^{3, 4} Gadola S.D....Cerundolo V. (2002)
CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease. (PubMed id 11580851)^{3, 6} Jones D.C....Bunce M. (2001)
Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts. (PubMed id 2701945)^{3, 4} Aruffo A. and Seed B. (1989)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 910	HGNC: 1635	AceView: CD1B	Ensembl:ENSG00000158485	euGenes: HUgn910
ECgene: CD1B	H-InvDB: CD1B

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for CD1B
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CD1B:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CD1B-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CD1B		Antibodies for CD1B
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CD1B		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (CD1, CD1b, CD1b+c)

Search OriGene for CD1B

Search Tocris compounds for CD1B

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CD1B

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CD1B Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for CD1B

Summaries
for CD1B

Genomic Location
for CD1B

Proteins
for CD1B

Protein Domains/
Families
for CD1B

Gene Function
for CD1B

Pathways & Interactions
for CD1B

Drugs & Compounds
for CD1B

Transcripts
for CD1B

Expression
for CD1B

Orthologs
for CD1B

Paralogs
for CD1B

SNPs/Variants
for CD1B

Disorders & Mutations
for CD1B

Medical News
for CD1B

Publications
for CD1B

Search for CD1B

Genome Databases showing CD1B

Other Databases showing CD1B

Specialized Databases showing CD1B

Licensable Technologies
for CD1B

Services
for CD1B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CD1B Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor CD1B

Summariesfor CD1B

Genomic Locationfor CD1B

Proteinsfor CD1B

Protein Domains/Familiesfor CD1B

Gene Functionfor CD1B

Pathways & Interactionsfor CD1B

Drugs & Compoundsfor CD1B

Transcriptsfor CD1B

Expression for CD1B

Orthologsfor CD1B

Paralogsfor CD1B

SNPs/Variantsfor CD1B

Disorders & Mutationsfor CD1B

Medical Newsfor CD1B

Publicationsfor CD1B

Search for CD1B

Genome Databases showing CD1B

Other Databases showing CD1B

Specialized Databases showing CD1B

Licensable Technologiesfor CD1B

Servicesfor CD1B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CD1B

Summaries
for CD1B

Genomic Location
for CD1B

Proteins
for CD1B

Protein Domains/
Families
for CD1B

Gene Function
for CD1B

Pathways & Interactions
for CD1B

Drugs & Compounds
for CD1B

Transcripts
for CD1B

Expression
for CD1B

Orthologs
for CD1B

Paralogs
for CD1B

SNPs/Variants
for CD1B

Disorders & Mutations
for CD1B

Medical News
for CD1B

Publications
for CD1B

Licensable Technologies
for CD1B

Services
for CD1B