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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CD1A Gene

protein-coding GIFtS: 63
GCID: GC01P158224

CD1a molecule

(Previous names: CD1A antigen, a polypeptide, CD1a antigen )
(Previous symbol: CD1)

Explore 56 diseases affiliated with
CD1A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CD1a Molecule¹ ²		R4²
CD1¹ ²		T6²
CD1A Antigen, A Polypeptide¹ ²		Cluster Of Differentiation 1 A²
CD1a Antigen¹ ³		Cortical Thymocyte Antigen CD1A²
HTa1 Thymocyte Antigen² ³		Differentiation Antigen CD1-Alpha-3²
T-Cell Surface Antigen T6/Leu-6² ³		Epidermal Dendritic Cell Marker CD1a²
FCB6²		T-Cell Surface Glycoprotein CD1a²
HTA1²

External Ids:	HGNC: 1634¹	Entrez Gene: 909²	Ensembl: ENSG00000158477⁷	OMIM: 188370⁵	UniProtKB: P06126³

Export aliases for CD1A gene to outside databases

Previous GC identifers: GC01P156016 GC01P153956 GC01P154952 GC01P155440 GC01P155038 GC01P156490 GC01P129582

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD1A:

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the

major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins

mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human

genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to

differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene

localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced

transcript variants have been observed, but their biological validity has not been determined. (provided by RefSeq,

Jul 2008)

UniProtKB/Swiss-Prot: CD1A_HUMAN, P06126

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to

T-cell receptors on natural killer T-cells

Gene Wiki entry for CD1A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CD1A gene promoter:
Bach1 Brachyury ATF-2 IRF-1 LCR-F1 POU2F1 POU2F1a MRF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CD1A promoter sequence

Search SABiosciences Chromatin IP Primers for CD1A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD1A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q23 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q22-q23

CD1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD1A gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P158224: view genomic region (about GC identifiers)

Start:	158,223,927 bp from pter	End:	158,228,059 bp from pter
Size:	4,133 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CD1A_HUMAN, P06126 (See protein sequence)

Recommended Name: T-cell surface glycoprotein CD1a precursor

Size: 327 amino acids; 37077 Da

Subunit: Heterodimer with B2M (beta-2-microglobulin). Interacts with CD74

Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to

intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts

Miscellaneous: During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by

lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to

the cell surface

2 PDB 3D structures from and Proteopedia for CD1A:

1ONQ (3D)

1XZ0 (3D)

Secondary accessions: D3DVD7 Q13962 Q5TDJ8 Q9UMM4 Q9Y5M5

Explore the universe of human proteins at neXtProt for CD1A: NX_P06126

CD1A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001754.2

ENSEMBL proteins:

ENSP00000289429

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	NAS	2447586
GO:0010008	endosome membrane	IEA	--
GO:0042612	MHC class I protein complex	IEA	--

CD1A for ontologies About GeneDecksing

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CD1A for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR011162 MHC_I/II-like_Ag-recog

IPR013783 Ig-like_fold

IPR003597 Ig_C1-set

IPR007110 Ig-like_dom

IPR011161 MHC_I-like_Ag-recog

Graphical View of Domain Structure for InterPro Entry P06126

ProtoNet protein and cluster: P06126

1 Blocks protein family: IPB003597 Immunoglobulin C-type

UniProtKB/Swiss-Prot: CD1A_HUMAN, P06126

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CD1A_HUMAN, P06126

Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to

T-cell receptors on natural killer T-cells

Genatlas biochemistry entry for CD1A:

cell differentiation antigen CD1A (T6),49kDa,membrane glycoprotein,B2M associated,identified by monoclonal antibodies

NA1/34,T6,VIT6,Leu6 (see CD1@)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD1A
		1 QIAGEN miScript miRNA Assays for microRNA that regulate CD1A:
		hsa-miR-589*
		SwitchGear 3'UTR luciferase reporter plasmid: CD1A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD1A

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15723809

CD1A for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Hematopoietic cell lineage

Hematopoietic cell lineage

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for CD1A):

Hematopoietic cell lineage

CD1A for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CD1A

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/49 Interacting proteins for CD1A (P06126^{1, 3} ENSP00000289429⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 49)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B2M	P61769¹^,³, ENSP00000340858⁴	EBI-1036766,EBI-714718 I2D: score=4 STRING: ENSP00000340858
AZGP1	ENSP00000292401⁴	STRING: ENSP00000292401
ENSG00000206435	ENSP00000372975⁴	STRING: ENSP00000372975
ENSG00000206452	ENSP00000383245⁴	STRING: ENSP00000383245
ENSG00000206505	ENSP00000373114⁴	STRING: ENSP00000373114

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006955	immune response	NAS	2447586
GO:0019882	antigen processing and presentation	IEA	--

CD1A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CD1A for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CD1A

10/519 HMDB Compounds for CD1A (see all 519) About this table

Compound	Synonyms	CAS #	PubMed Ids
3-Dehydrosphinganine	1-Hydroxy-2-amino-3-oxo-octadecane (see all 9)	16105-69-4	--
3-O-Sulfogalactosylceramide (d18:1/12:0)	Sulfatide (d18:1/12:0) (see all 13)	852100-88-0	--
3-O-Sulfogalactosylceramide (d18:1/14:0)	Sulfatide (d18:1/14:0) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/16:0)	Sulfatide (d18:1/16:0) (see all 13)	862509-48-6	--
3-O-Sulfogalactosylceramide (d18:1/18:0)	Sulfatide (d18:1/18:0) (see all 13)	244215-65-4	--
3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))	Sulfatide (d18:1/18:1(9Z)) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/20:0)	Sulfatide (d18:1/20:0) (see all 13)	265096-81-9	--
3-O-Sulfogalactosylceramide (d18:1/22:0)	Sulfatide (d18:1/22:0) (see all 13)	265096-83-1	--
3-O-Sulfogalactosylceramide (d18:1/24:0)	Sulfatide (d18:1/24:0) (see all 16)	151122-71-3	--
3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))	Sulfatide (d18:1/24:1(15Z)) (see all 13)	151057-28-2	--

1 DrugBank Compound for CD1A About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Antithymocyte globulin	rabbit ATG (see all 3)	--	target	inhibitor	17139284 11752352 17016423

2 Novoseek chemical compound relationships for CD1A gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
glycolipid	76.1	8	12391186 (1), 10352272 (1), 17428545 (1), 11035089 (1) (see all 8)
lipid	48.3	48	20026739 (4), 17593658 (4), 10487835 (3), 9987600 (3) (see all 32)

Search CenterWatch for drugs/clinical trials and news about CD1A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CD1A gene:

NM_001763.2

Unigene Cluster for CD1A:

CD1a molecule

Hs.1309 [show with all ESTs]

Unigene Representative Sequence: NM_001763

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000289429(uc001frt.3 uc021pbk.1)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD1A
		1 QIAGEN miScript miRNA Assays for microRNA that regulate CD1A:
		hsa-miR-589*
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD1A

Additional cDNA sequence:

AK312945.1 BC031645.1 M27735.1 M28825.1 X04450.1

8 DOTS entries:

DT.100776245 DT.121377677 DT.121377701 DT.111387 DT.121377691 DT.92416233 DT.100644955 DT.121377683

24/30 AceView cDNA sequences (see all 30):

CR603267 BG679322 L44433 AI581337 X79308 AA354298 CA432941 AA310607

BX281603 BC031645 M27735 BI828464 X04450 BV202113 AI240210 AW949640

NM_001763 BX414919 AW303389 M28825 AA354975 AA310389 AA731869 AV717068

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CD1A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCTCAATAA

About this image

CD1A expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Blood

Peripheral Blood

T-Cytotoxic Cells

Blood

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Dendritic-like cells (Generation of hemato...)

See CD1A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CD1A

SOURCE GeneReport for Unigene cluster: Hs.1309

UniProtKB/Swiss-Prot: CD1A_HUMAN, P06126

Tissue specificity: Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell

leukemias, and in various other tissues

SABiosciences Expression via Pathway-Focused PCR Arrays including CD1A:

Cell Surface Markers in human mouse rat

Antigen Presenting Cells in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD1A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CD1A gene from 3/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GGA.29894⁶	Uncharacterized protein	21(a)	1 → many	16(1371-11718)
lizard (Anolis carolinensis)	Reptilia	--	--	25(a)	1 → many	2(189406880-189414378)
zebrafish (Danio rerio)	Actinopterygii	mhc1uba⁶ BX572619.3⁶ (see all 16)	--	18(a) 18(a) (see all 16)	possible ortholog many ↔ many (see all 16)	19(7695390-7723636) 25(11071636-11074578)

ENSEMBL Gene Tree for CD1A (if available)
TreeFam Gene Tree for CD1A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CD1A gene

CD1D² CD1B² CD1C² CD1E²

6 SIMAP similar genes for CD1A using alignment to 2 protein entries: CD1A_HUMAN (see all proteins):

CDIE CD1E CD1C CD1D CD1B B2M

CD1A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs111814129^1,2	F	--	129582658(+)	`TGTGTG/CTGTGT`	1	--	int¹		2		CSA	4
rs113802547^1,2	F	--	129582660(+)	`TGTGTG/CTGTGT`	1	--	int¹		2		CSA	4
rs192966029^1,2		--	158222097(+)	`AAAGGC/TTTAGA`	1	--	us2k¹		0	--	--	--	--
rs116411535^1,2		--	158222245(+)	`AACAAG/AGGTTT`	1	--	us2k¹		1		NA	120
rs183094419^1,2		--	158222254(+)	`TTGCAC/TTCCAT`	1	--	us2k¹		0	--	--	--	--
rs150838405^1,2	C,	--	158222455(+)	`TGGGA-/GGGCTG`	1	--	us2k¹		0	--	--	--	--
rs187255641^1,2		--	158222466(+)	`CTGAGA/GCAGGT`	1	--	us2k¹		0	--	--	--	--
rs145386419^1,2		--	158222611(+)	`TTAACA/CTGGGA`	1	--	us2k¹		0	--	--	--	--
rs61818715^1,2		--	158222676(+)	`GAGTGG/AGACTC`	1	--	us2k¹		1		NA	2
rs192109737^1,2		--	158222700(+)	`AACAAA/TACAAA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CD1A (158223927 - 158228059 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CD1A
1 CNV: 48143
Human Gene Mutation Database (HGMD): CD1A

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CD1A

DNA2.0 Custom Variant and Variant Library Synthesis for CD1A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CD1A for disorders           About GeneDecksing

OMIM gene information: 188370    OMIM disorders: --

20/56 diseases for CD1A (see all 56):    About MalaCards

langerhans-cell histiocytosis guillain-barre syndrome mycobacterium malmoense mycosis fungoides

epidermodysplasia verruciformis actinic cheilitis lichen planus barrett's esophagus

oral lichen planus cyclosporiasis histiocytosis cheilitis

langerhans cell sarcoma monocytic leukemia acute monocytic leukemia diabetes insipidus

cystic teratoma aggressive periodontitis bronchial asthma teratoma

4 diseases from the University of Copenhagen DISEASES database for CD1A:

Myocardial infarction Cancer Langerhans-cell histiocytosis Cyclosporiasis

10/16 Novoseek disease relationships for CD1A gene (see all 16) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
langerhans cell histiocytosis	77	4	14576638 (1), 20439325 (1), 18277880 (1)
histiocytosis	68.2	2	17378241 (1), 12717600 (1)
eosinophilic granuloma	58.8	1	20074763 (1)
sarcoma	23.8	2	18360746 (1), 20439325 (1)
mycosis fungoides	22.4	1	7593815 (1)
tuberculosis	18.3	2	19808251 (1), 16034117 (1)
barrett esophagus	14.5	2	17308274 (1)
tumors	9.99	7	12865628 (1), 16243135 (1), 15914364 (1), 18047662 (1) (see all 6)
autoimmunity	3.87	1	18593354 (1)
infectious disease	2.34	2	9973451 (1), 14991068 (1)

Genetic Association Database (GAD): CD1A
Human Genome Epidemiology (HuGE) Navigator: CD1A (9 documents)

Export disorders for CD1A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CD1A gene, integrated from 9 sources (see all 210):
(articles sorted by number of sources associating them with CD1A)

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Molecular cloning of CD1a (T6), a human epidermal dendritic cell marker related to class I MHC molecules. (PubMed id 2784820)^{1, 2, 3} Longley J.... Edelson R. (1989)
Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. (PubMed id 2447586)^{1, 2, 3} Martin L.H.... Milstein C. (1987)
CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease. (PubMed id 11580851)^{1, 4, 9} Jones D.C....Bunce M. (2001)
Regulation of CD1a surface expression and antigen presentation by invariant chain and lipid rafts. (PubMed id 18178838)^{1, 2} Sloma I.... Gelin C. (2008)
CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens. (PubMed id 16272286)^{1, 2} Vincent M.S.... Brenner M.B. (2005)
Molecular mechanism of lipopeptide presentation by CD1a. (PubMed id 15723809)^{1, 2} Zajonc D.M....Wilson I.A. (2005)
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A. (PubMed id 12833155)^{1, 2} Zajonc D.M.... Wilson I.A. (2003)
Polymorphism of human CD1 genes. (PubMed id 10488738)^{1, 2} Han M.... Robinson M.A. (1999)
Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts. (PubMed id 2701945)^{1, 2} Aruffo A. and Seed B. (1989)
A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6. (PubMed id 3093894)^{1, 2} Calabi F. and Milstein C. (1986)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 909	HGNC: 1634	AceView: CD1A	Ensembl:ENSG00000158477	euGenes: HUgn909
ECgene: CD1A	Kegg: 909	H-InvDB: CD1A

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CD1A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CD1A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CD1A gene:
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