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CD19 Gene

protein-coding GIFtS: 72

GC16P028850

CD19 molecule
(Previous name: CD19 antigen )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
B4 ^²
Leu-12 ^³
MGC12802 ^²

Descriptions
B-lymphocyte antigen CD19 ^²
B-lymphocyte surface antigen B4 ^³
CD19 antigen ^¹, ², ³
CD19 molecule ^²
Differentiation antigen CD19 ^³

External Ids
HGNC: 1633¹
Entrez Gene: 930²
UniProtKB: P15391³
Ensembl: ENSG00000177455⁷

Search outside databases for aliases for CD19 gene

Previous GC identifers: GC16U990011 GC16P029266 GC16P028941 GC16P028980

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CD19:

Lymphocytes proliferate and differentiate in response to various concentrations of different

antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various

antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell

surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease

the threshold for antigen receptor-dependent stimulation. [provided by RefSeq]

UniProtKB/Swiss-Prot: CD19_HUMAN, P15391

Function: Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold

for antigen receptor-dependent stimulation

Gene Wiki entry for CD19

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CD19 gene

Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2

CD19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P028850: (about GC identifiers)

Start:	28,850,761 bp from pter
End:	28,858,164 bp from pter
Size:	7,404 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000016.8 NT_010393.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CD19_HUMAN, P15391 (See protein sequence)

Recommended Name: B-lymphocyte antigen CD19 precursor

Size: 556 amino acids; 61128 Da

Subunit: Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. Interacts

with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. Interacts

with PLCG2 when phosphorylated on Tyr-409

Subcellular location: Membrane; Single-pass type I membrane protein

Sequence caution: Sequence=AAA35533.1; Type=Frameshift; Positions=396;

Secondary accessions: Q96S68 Q9BRD6

Post-translational modifications:

Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on

tyrosine following B-cell activation¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001761.3

ENSEMBL proteins:

ENSP00000370048 ENSP00000313419

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich CompoZr ZFN for CD19
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD3 + CD19, CD10 + CD19, Kappa + CD19, CD2 + CD19, CD19, CD3 + CD19 + CD45, Lambda + CD19, CD86 + CD19, CD5 + CD19)
	Human Recombinant Proteins from Abnova (CD19)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	2472450
GO:0005887	integral to plasma membrane	TAS	2472450
GO:0009897	external side of plasma membrane	IEA	--

About this table

Antibodies for CD19:

	Invitrogen Antibodies for CD19
	Millipore Mono- and Polyclonal Antibodies for the study of CD19
	Sigma-Aldrich Antibodies for CD19
	R&D Systems Antibodies for CD19
	Cell Signaling Technology (CST) Antibodies for CD19
	Antibodies from Abcam (CD3 + CD19, CD10 + CD19, Kappa + CD19, CD2 + CD19, CD19, CD3 + CD19 + CD45, Lambda + CD19, CD86 + CD19, CD5 + CD19), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CD19)
	Novus Biologicals Antibodies for CD19

Assays for CD19:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P15391

ProtoNet protein and cluster: P15391

1 Blocks protein family: IPB003599 Immunoglobulin subtype

UniProtKB/Swiss-Prot: CD19_HUMAN, P15391

Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD19)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CD19)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001770

Applied Biosystems Silencer® siRNAs for CD19

Sigma-Aldrich siRNA for CD19

Sigma-Aldrich shRNA Panels and shRNA for CD19

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CD19
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001770
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001770
untagged cDNA clone in CMV expression vector: NM_001770

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001770

UniProtKB/Swiss-Prot: CD19_HUMAN, P15391

Function: Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold

for antigen receptor-dependent stimulation

Genatlas biochemistry entry for CD19:

cell differentiation antigen CD19,95kDa,B cell surface membrane protein PAX5 (BSAP)

dependent,identified by monoclonal antibodies B4,HD37 and others ,linked to the integrin

associated CD9,CD81,KAI1

11 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Cd19):

	cellular	digestive/alimentary	hematopoietic system	homeostasis/metabolism
immune system	life span-post-weaning/aging	liver/biliary system	normal	renal/urinary system
tumorigenesis

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005057	receptor signaling protein activity	TAS	1373518
GO:0005515	protein binding	IPI	8647200

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for CD19 (Your Favorite Gene powered by Ingenuity)

B Cell Receptor Signaling

GeneDecks CD19 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for CD19

5/131 Interacting proteins for CD19 (ENSP00000313419³ P15391¹) via UniProtKB, MINT, and/or STRING (see all 131 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PIK3R3	Q92569¹	STRING (score=.955) EBI-79902, EBI-79893
CD81	ENSP00000370424³	STRING (score=.999)
CR2	ENSP00000356024³	STRING (score=.999)
CD79B	ENSP00000006750³	STRING (score=.998)
VAV1	ENSP00000302269³	STRING (score=.997)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006968	cellular defense response	TAS	1373518
GO:0007166	cell surface receptor linked signal transduction	TAS	1714482
GO:0050853	B cell receptor signaling pathway	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CD19
5 Novoseek chemical compound relationships for CD19 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
ricin	49.03	2	1370636 (1)
phosphatidylinositol	40.99	8	9808169 (2), 7688513 (1), 10201980 (1), 9190913 (1) (see all 5)
tyrosine	28.32	25	9808169 (3), 9200454 (3), 12938232 (2), 10933394 (2) (see all 12)
lipid	0.00	3	9620684 (2), 11713294 (1)
calcium	0.00	3	9620684 (1), 11584010 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CD19)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CD19)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001770

Sigma-Aldrich siRNA for CD19

Sigma-Aldrich shRNA Panels and shRNA for CD19

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001770

REFSEQ mRNAs for CD19 gene:

NM_001770.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001770

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001770
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001770
                                 untagged cDNA clone in CMV expression vector: NM_001770

Additional cDNA sequence:

AK130657.1 AK301167.1 AK301363.1 AK304456.1 AK307295.1 AK313577.1 BC006338.2 BC052294.1

M21097.1 X13312.1

6 DOTS entries:

DT.454928 DT.99961528 DT.95082330 DT.95268084 DT.91833223 DT.95268082

24/58 AceView cDNA sequences (see all 58 ):

AW574858 BP340570 BQ055377 BP340638 BX094429 BQ066405 BG258419 BI769680

AK130657 BC006338 BC052294 AW402245 NM_001770 BF238170 BG341660 BQ063609

BI837054 BQ709716 BM801076 BF975777 BG342178 BG754924 BQ057181 BG758327

highest scoring ESTs for CD19:

AA760729 AI217645 AI356451 AI384038 AI475697 AI805108 AW574858 AW976846 BC006338 BC052294

Unigene Cluster for CD19:

CD19 molecule

Hs.652262 [show with all ESTs]

Unigene Representative Sequence: BC052294

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CD19 (see all 6 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10a	·	10b	^	11	^	12	^	13	^	14	^	15	^	16	^	17
SP1:															-																-
SP2:													-		-		-		-												-
SP3:									-		-		-		-
SP4:																																									-
SP5:											-				-

About this scheme

ECgene alternative splicing isoforms for CD19

2 Ensembl transcripts including schematic representations:

ENST00000380673 ENST00000324662

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CD19 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CD19

¹ / ² / ³

4 probe-sets matching CD19 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1096_g_at²^{, 3}	U95-A	1	1.00	1.00	0.96	1.03	M28170	0.80	1.00	0.91	1
1116_at*²^{, 3}	U95-A	1	1.00	1.00	0.70	0.98	M28170	0.80	1.00	0.91	1
206398_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001770	0.60	1.00	0.82	1
206398_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CD19 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGGAAGATGC

SOURCE GeneReport for Unigene cluster: Hs.652262
Expression variation in blood from EXPOLDB for CD19

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CD19 gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CD19¹	--	CD19 molecule	81.76(n) 72.83(a)	607898 XM_855206.1 XP_860299.1
chimpanzee (Pan troglodytes)	CD19¹	--	CD19 molecule	99.59(n) 99.75(a)	454020 XM_510906.2 XP_510906.2
rat (Rattus norvegicus)	Cd19¹	--	CD19 molecule	75.65(n) 66.97(a)	365367 XM_344961.3 XP_344962.3
mouse (Mus musculus)	Cd19^{1, 5}	7 (59.00 cM)⁵	CD19 antigen^{1, 5}	76.41(n)¹ 67.46(a)¹	12478¹ NM_009844.1¹ NP_033974.1¹ AK089835⁵ AK156125⁵ (see all 17)

About this table Species with no ortholog for CD19

ENSEMBL Gene Tree for CD19

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/32 NCBI SNPs in CD19 are shown (see all 32 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 12)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2904880^1,2	C,F,H	28851897(+)	`CGTGTG/CTCCCA`	1	V/L	mis¹ ese³		9		EU EA WA NA	898
	rs34763945^1,2	C,F	28857552(+)	`GCTCCG/ACTCCA`	1	H/R	mis¹		5		NA EU EA WA	494
--	rs8060534^1,2	A,C	28848981(+)	`cctgcC/Tttggc`	1	--	ng5¹		0	--	--	--	--
	rs35979293^1,2	F	28852201(+)	`CGCCCG/TGCCAG`	1	P/P	syn¹		1		NA	74
	rs2070962^1,2	A,C,F	28857933(+)	`CTGGAC/TCCCTC`	1	--	int¹		3		NA	142
	rs2070961^1,2	C,F,H	28856974(+)	`GACTCC/TGACTC`	1	--	int¹		8		EA NA EU WA	2036
--	rs2032907^1,2	H	28856797(-)	`CAGGAT/GGGGGG`	1	--	int¹		1		EU	120
--	rs12597186^1,2	C	28857186(+)	`ttggcC/Tagact`	1	--	int¹		0	--	--	--	--
	rs2904881^1,2	H	28856270(+)	`CTTCTC/ACACCA`	1	--	int¹ trp³		1		EU	120
--	rs10633752^1,2	--	28858075(+)	`tgtaa-/GTGT gtgtg`	1	--	ut3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for CD19 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 107265

UniProtKB/Swiss-Prot: CD19_HUMAN, P15391

Defects in CD19 are a cause of hypogammaglobulinemia [MIM:107265]

10/11 Novoseek disease relationships for CD19 gene (see all 11 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
lymphoblastic leukemia acute	69.35	1	7517719 (1)
leukemia lymphocytic chronic	64.57	1	7691238 (1)
plasma cell myeloma	57.96	2	12002767 (1), 8639790 (1)
leukemia	57.66	4	1705571 (1), 9684930 (1), 9566763 (1), 8528044 (1)
myeloma	54.59	7	10201980 (2), 8639790 (1)
b-all	48.47	4	16185473 (2), 16939815 (1)
lymphoma	48.33	4	1705571 (1), 1692257 (1), 9566763 (1), 8528044 (1)
blast crisis	45.61	1	1518143 (1)
lymphoma non-hodgkins	33.94	2	1706642 (1), 7517719 (1)
lymphoma b-cell	21.70	1	16506527 (1)

About this table

1 PharmGKB disease relationship for CD19 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872 12730115

About this table

GeneTests: CD19

Common Variable Immune Deficiency

Human Gene Mutation Database: CD19
Genetic Association Database: CD19
Human Genome Epidemiology Navigator: CD19 (8 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

AIDS-VACCINE: Low Iinterleukin-10 Production Linked To Diabetes In Patients On Highly Active Antiretroviral Therapy

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/155 PubMed articles for CD19 gene (see all 155 ):

Polymorphisms of human CD19 gene: possible association with susceptibility to systemic lupus erythematosus in Japanese. (PubMed id 12215898)^{3, 4, 6} Kuroki K.... Tokunaga K. (2002)
Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes. (PubMed id 1370948)^{1, 3, 4} Zhou L.J.... Tedder T.F. (1992)
An antibody-deficiency syndrome due to mutations in the CD19 gene. (PubMed id 16672701)^{3, 4} van Zelm M.C.... Franco J.L. (2006)
Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis. (PubMed id 15593213)^{3, 6} Tsuchiya N....Sato S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines. (PubMed id 10706702)^{3, 4} Brooks S.R.... Carter R.H. (2000)
The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP. (PubMed id 1375324)^{3, 4} Kozmik Z.... Busslinger M. (1992)
Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. (PubMed id 2472450)^{3, 4} Tedder T.F. and Isaacs C.M. (1989)
CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein- Barr virus-related cytoplasmic tail. (PubMed id 2459292)^{3, 4} Stamenkovic I. and Seed B. (1988)
CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification. (PubMed id 10933394)^{1, 3} Fujimoto M....Tedder T.F. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 930	HGNC: 1633	AceView: CD19	Ensembl:ENSG00000177455	euGenes: HUgn930
ECgene: CD19	H-InvDB: CD19

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CD19	Genetics and Cytogenetics in Oncology and Haematology
CD19base	http://bioinf.uta.fi/CD19base/
GeneReviews	http://www.genetests.org/query?gene=CD19

Licensable Technologies for CD19
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CD19:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CD19-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CD19		Antibodies for CD19
	Explore super-pooled esiRNAs		Proteins for CD19
	Lentivirus-delivered shRNAs for CD19		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CD19)
	Antibodies (CD19)
	Chimera RNAi (CD19)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for CD19

	Recombinant Proteins (CD3 + CD19, CD10 + CD19, Kappa + CD19, CD2 + CD19, CD19, CD3 + CD19 + CD45, Lambda + CD19, CD86 + CD19, CD5 + CD19)
	Antibodies (CD3 + CD19, CD10 + CD19, Kappa + CD19, CD2 + CD19, CD19, CD3 + CD19 + CD45, Lambda + CD19, CD86 + CD19, CD5 + CD19)

Search OriGene for CD19

Search Tocris compounds for CD19

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CD19

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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CD19 Gene at Home site.
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CD19 Gene

protein-coding GIFtS: 72

Aliases &
Descriptions
for CD19

Summaries
for CD19

Genomic Location
for CD19

Proteins
for CD19

Protein Domains/
Families
for CD19

Gene Function
for CD19

Pathways & Interactions
for CD19

Drugs & Compounds
for CD19

Transcripts
for CD19

Expression
for CD19

Orthologs
for CD19

Paralogs
for CD19

SNPs/Variants
for CD19

Disorders & Mutations
for CD19

Medical News
for CD19

Publications
for CD19

Search for CD19

Genome Databases showing CD19

Other Databases showing CD19

Specialized Databases showing CD19

Licensable Technologies
for CD19

Services
for CD19

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CD19 Gene

protein-coding GIFtS: 72

Aliases & Descriptionsfor CD19

Summariesfor CD19

Genomic Locationfor CD19

Proteinsfor CD19

Protein Domains/Familiesfor CD19

Gene Functionfor CD19

Pathways & Interactionsfor CD19

Drugs & Compoundsfor CD19

Transcriptsfor CD19

Expression for CD19

Orthologsfor CD19

Paralogsfor CD19

SNPs/Variantsfor CD19

Disorders & Mutationsfor CD19

Medical Newsfor CD19

Publicationsfor CD19

Search for CD19

Genome Databases showing CD19

Other Databases showing CD19

Specialized Databases showing CD19

Licensable Technologiesfor CD19

Servicesfor CD19

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CD19

Summaries
for CD19

Genomic Location
for CD19

Proteins
for CD19

Protein Domains/
Families
for CD19

Gene Function
for CD19

Pathways & Interactions
for CD19

Drugs & Compounds
for CD19

Transcripts
for CD19

Expression
for CD19

Orthologs
for CD19

Paralogs
for CD19

SNPs/Variants
for CD19

Disorders & Mutations
for CD19

Medical News
for CD19

Publications
for CD19

Licensable Technologies
for CD19

Services
for CD19