Aliases for CD180 Gene
Aliases for CD180 Gene
External Ids for CD180 Gene
- HGNC: 6726
- Entrez Gene: 4064
- Ensembl: ENSG00000134061
- OMIM: 602226
- UniProtKB: Q99467
Previous HGNC Symbols for CD180 Gene
- LY64
Previous GeneCards Identifiers for CD180 Gene
- GC05M066514
- GC05M063436
Summaries for CD180 Gene
-
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD180 Gene
CD180 (CD180 Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Activated TLR4 signalling. An important paralog of this gene is TLR4.
UniProtKB/Swiss-Prot for CD180 Gene
-
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD180 Gene
Genomics for CD180 Gene
Regulatory Elements for CD180 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH05G067163 | 1.2 | Ensembl ENCODE dbSUPER | 12.7 | +30.7 | 30683 | 4.7 | CTCF TEAD4 RBBP5 RAD21 EGR1 POLR2A ZNF143 SMC3 KDM1A ZNF24 | CD180 GC05P067163 GC05M067180 |
| GH05G067158 | 1.2 | Ensembl ENCODE dbSUPER | 12.3 | +36.2 | 36243 | 4.8 | GTF2F1 PKNOX1 JUN RFX5 GATA3 SCRT2 SMC3 FOSL2 FOS TCF7L2 | CD180 GC05P067163 MAST4-AS1 |
| GH05G067002 | 1.3 | ENCODE dbSUPER | 7.8 | +191.3 | 191251 | 6.0 | PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 | MAST4-AS1 CD180 GC05P067163 |
| GH05G067192 | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 6.3 | +1.9 | 1899 | 5.0 | RAD51 FOXA2 USF1 POLR2A IKZF1 IKZF2 SPI1 | MAST4-AS1 CD180 MAST4 GC05M067180 |
| GH05G067187 | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 5.1 | +8.5 | 8512 | 2.2 | SIX4 ZNF274 PKNOX1 ZNF316 MAFG EMSY MAFK SPI1 | CD180 GC05M067180 |
- Transcription factor binding sites by QIAGEN in the CD180 gene promoter:
Regulatory Element Products
Genomic Location for CD180 Gene
- Chromosome:
- 5
- Start:
- 67,179,613 bp from pter
- End:
- 67,196,799 bp from pter
- Size:
- 17,187 bases
- Orientation:
- Minus strand
Genomic View for CD180 Gene
- Cytogenetic band:
-
- 5q12.3 by Ensembl
- 5q12.3 by Entrez Gene
- 5q12.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CD180 Gene
Proteins for CD180 Gene
-
Protein details for CD180 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99467-CD180_HUMAN
- Recommended name:
- CD180 antigen
- Protein Accession:
- Q99467
- B2R7Z7
- Q32MM5
Protein attributes for CD180 Gene
- Size:
- 661 amino acids
- Molecular mass:
- 74179 Da
- Quaternary structure:
-
- M-shaped tetramer of two CD180-LY86 heterodimers.
Protein Expression for CD180 Gene
Post-translational modifications for CD180 Gene
Other Protein References for CD180 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CD180
-
Custom Antibody ServicesOriGene Antibodies for CD180
- Novus Biologicals Antibodies for CD180
- Invitrogen Antibodies for CD180
- antibodies-online Antibodies for CD180: See all 142
- GeneTex CD180 antibody for CD180
-
Custom Antibody ServicesProSci Antibodies for CD180
-
Santa Cruz Biotechnology (SCBT) Antibodies for CD180
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CD180
- Origene Custom Protein Services for CD180
- Novus Biologicals proteins for CD180
- Sino Biological Recombinant Proteins for CD180
- Sino Biological Cell Lysates for CD180
- antibodies-online Proteins for CD180: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CD180
Assay Products
- antibodies-online Kits for CD180: See all 2
No data available for DME Specific Peptides for CD180 Gene
Domains & Families for CD180 Gene
Gene Families for CD180 Gene
- HGNC:
Protein Domains for CD180 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CD180 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q99467- Family:
-
- Belongs to the Toll-like receptor family.
Function for CD180 Gene
Molecular function for CD180 Gene
- UniProtKB/Swiss-Prot Function:
- May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004872 | receptor activity | IBA | -- |
Phenotypes for CD180 Gene
- MGI mutant phenotypes for CD180:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CD180:
Animal Models for CD180 Gene
- MGI Knock Outs for CD180:
-
- Cd180 tm1Kmiy
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD180
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CD180 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD180 gene
- Search ViGene Biosciences for CD180
CRISPR Products
-
OriGene CRISPR knockouts for CD180
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD180
- GenScript: Design CRISPR guide RNA sequences for CD180
miRNA for CD180 Gene
- miRTarBase miRNAs that target CD180
-
- hsa-mir-4291 (MIRT496004)
- hsa-mir-3622b-5p (MIRT496005)
- hsa-mir-107 (MIRT496006)
- hsa-mir-103a-3p (MIRT496007)
- hsa-mir-5702 (MIRT496008)
- hsa-mir-761 (MIRT496009)
- hsa-mir-3619-5p (MIRT496010)
- hsa-mir-214-3p (MIRT496011)
- hsa-mir-922 (MIRT496012)
- hsa-mir-6838-5p (MIRT496013)
- hsa-mir-497-5p (MIRT496014)
- hsa-mir-424-5p (MIRT496015)
- hsa-mir-195-5p (MIRT496016)
- hsa-mir-16-5p (MIRT496017)
- hsa-mir-15b-5p (MIRT496018)
- hsa-mir-15a-5p (MIRT496019)
- hsa-mir-1277-5p (MIRT519161)
- hsa-mir-190a-3p (MIRT519162)
- hsa-mir-4789-5p (MIRT519163)
- hsa-mir-3941 (MIRT519164)
- hsa-mir-5011-5p (MIRT519165)
- hsa-mir-4789-3p (MIRT519166)
- hsa-mir-603 (MIRT519167)
- hsa-mir-362-3p (MIRT519168)
- hsa-mir-329-3p (MIRT519169)
- hsa-mir-8485 (MIRT519170)
- hsa-mir-5192 (MIRT612094)
- hsa-mir-4644 (MIRT612095)
- hsa-mir-4306 (MIRT612096)
- hsa-mir-185-5p (MIRT612097)
- hsa-mir-6514-5p (MIRT612098)
- hsa-mir-8076 (MIRT612099)
- hsa-mir-4802-5p (MIRT612100)
- hsa-mir-5580-3p (MIRT612101)
miRNA Products
- Search ViGene Biosciences for CD180
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
-
ViGene Biosciences ready-to-package AAV shRNAs for CD180 gene
Clone Products
-
OriGene ORF clones in human for CD180
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CD180
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CD180
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD180
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CD180
-
ViGene Biosciences adenoviral particle packaged cDNA for CD180 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CD180 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD180 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CD180 Gene
Localization for CD180 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CD180 Gene
- Cell membrane; Single-pass type I membrane protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0005887 | integral component of plasma membrane | IBA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CD180 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Activated TLR4 signalling | ||
| 3 | IL-2 Pathway | ||
| 4 | Toll-like Receptor Signaling Pathway | ||
Pathways by source for CD180 Gene
1 BioSystems pathway for CD180 Gene
4 Reactome pathways for CD180 Gene
1 Qiagen pathway for CD180 Gene
Interacting Proteins for CD180 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002224 | toll-like receptor signaling pathway | IBA | -- |
| GO:0002322 | B cell proliferation involved in immune response | IEA | -- |
| GO:0002376 | immune system process | IEA | -- |
| GO:0006954 | inflammatory response | IEA,IBA | -- |
| GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway | IGI | 10880523 |
No data available for SIGNOR curated interactions for CD180 Gene
Transcripts for CD180 Gene
mRNA/cDNA for CD180 Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (41) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CD180
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD180
- GenScript: Design CRISPR guide RNA sequences for CD180
miRNA Products
- Search ViGene Biosciences for CD180
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
-
ViGene Biosciences ready-to-package AAV shRNAs for CD180 gene
Clone Products
-
OriGene ORF clones in human for CD180
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CD180
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CD180
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD180
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CD180 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CD180 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CD180 Gene
NURSA nuclear receptor signaling pathways regulating expression of CD180 Gene:
CD180SOURCE GeneReport for Unigene cluster for CD180 Gene:
Hs.87205mRNA Expression by UniProt/SwissProt for CD180 Gene:
Q99467-CD180_HUMANEvidence on tissue expression from TISSUES for CD180 Gene
- Liver(4.1)
- Lung(4.1)
- Blood(2.3)
- Spleen(2.3)
- Lymph node(2.2)
Primer Products
-
OriGene qPCR primer pairs for CD180
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CD180 Gene
Orthologs for CD180 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CD180 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CD180 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CD180 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cd180 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cd180 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CD180 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CD180 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CD180 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CD180 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cd180 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC101885327 34 |
|
||
| CD180 (2 of 2) 35 |
|
OneToMany | |||
| cd180 35 |
|
OneToMany |
- Species where no ortholog for CD180 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CD180 Gene
Variants for CD180 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000525980 | -- | 67,194,825(+) | CCCCC(A/C)CCACC | intron-variant | |
| rs1000688290 | -- | 67,188,604(+) | CGAGT(C/T)ACAAA | intron-variant | |
| rs1001040593 | -- | 67,189,666(+) | CAAAA(C/T)GGCCA | intron-variant | |
| rs1001097078 | -- | 67,189,268(+) | GTGCT(C/T)TACTA | intron-variant | |
| rs1001737672 | -- | 67,189,141(+) | GACTT(C/G)CTCAG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759347 | CNV | gain | 17122850 |
Relevant External Links for CD180 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CD180
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD180 Gene
Disorders for CD180 Gene
Relevant External Links for CD180
No disorders were found for CD180 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CD180 Gene
Publications for CD180 Gene
- RP105 is associated with MD-1 and transmits an activation signal in human B cells. (PMID: 9763566) Miura Y. … Kimoto M. (Blood 1998) 2 3 4 22 64
- Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). (PMID: 8975706) Miura Y. … Kimoto M. (Genomics 1996) 2 3 4 22 64
- A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S. … Sun J. (Carcinogenesis 2012) 3 46 64
- Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family. (PMID: 21959264) Ohto U. … Shimizu T. (J. Mol. Biol. 2011) 3 4 64
- Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PMID: 20331378) Mosbruger T.L. … Thio C.L. (J. Infect. Dis. 2010) 3 46 64
Products for CD180 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CD180
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CD180
- Origene Custom Protein Services for CD180
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
- OriGene qPCR primer pairs for CD180
- OriGene CRISPR knockouts for CD180
- OriGene ORF clones in human for CD180
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for CD180 in any vector
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- GenScript Custom Assay Services for CD180
- GenScript Custom overexpressing Cell Line Services for CD180
- GenScript: Design CRISPR guide RNA sequences for CD180
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CD180
- Sino Biological Human cDNA Clone for CD180
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- Sino Biological Cell Lysates for CD180
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CD180
- Novus Biologicals proteins for CD180
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for CD180: See all 142
- antibodies-online Kits for CD180: See all 2
- antibodies-online Proteins for CD180: See all 5
- Search antibodies-online for peptides
- GeneTex CD180 antibody for CD180
- Search GeneTex for Proteins for CD180
- ViGene Biosciences adenoviral particle packaged cDNA for CD180 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CD180 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CD180 gene
- Search ViGene Biosciences for CD180
- Santa Cruz Biotechnology (SCBT) Antibodies for CD180
- Search Santa Cruz Biotechnology (SCBT) for CD180 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CD180
- Custom Antibody ServicesProSci Antibodies for CD180
- Search for CD180 Proteins at ProSci
- Horizon Cell Lines for CD180
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD180
- VectorBuilder custom plasmid, inducible vectors for CD180
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD180
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CD180 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




