Aliases for CD177 Gene
Aliases for CD177 Gene
External Ids for CD177 Gene
- HGNC: 30072
- Entrez Gene: 57126
- Ensembl: ENSG00000204936
- OMIM: 162860
- UniProtKB: Q8N6Q3
Previous GeneCards Identifiers for CD177 Gene
- GC19P048550
- GC19P043857
- GC19P040287
Summaries for CD177 Gene
-
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
GeneCards Summary for CD177 Gene
CD177 (CD177 Molecule) is a Protein Coding gene. Diseases associated with CD177 include Polycythemia and Essential Thrombocythemia. Among its related pathways are Innate Immune System and Cell surface interactions at the vascular wall. An important paralog of this gene is TEX101.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD177 Gene
Genomics for CD177 Gene
Regulatory Elements for CD177 Gene
Enhancers for CD177 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CD177 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CD177 gene promoter:
Regulatory Element Products
Genomic Location for CD177 Gene
- Chromosome:
- 19
- Start:
- 43,353,659 bp from pter
- End:
- 43,363,172 bp from pter
- Size:
- 9,514 bases
- Orientation:
- Plus strand
Genomic View for CD177 Gene
Genes around CD177 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.31 by Ensembl
- 19q13.31 by Entrez Gene
- 19q13.31 by HGNC
CD177 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CD177 Gene
Proteins for CD177 Gene
-
Protein details for CD177 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N6Q3-CD177_HUMAN
- Recommended name:
- CD177 antigen
- Protein Accession:
- Q8N6Q3
- Q711Q2
- Q8NCV9
- Q96QH1
- Q9HDA5
Protein attributes for CD177 Gene
- Size:
- 437 amino acids
- Molecular mass:
- 46363 Da
- Quaternary structure:
- No Data Available
Protein Expression for CD177 Gene
Post-translational modifications for CD177 Gene
- A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding).
- N-glycosylated.
- Glycosylation at Asn189
Other Protein References for CD177 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CD177 (CD177)
- Novus Biologicals Antibodies for CD177
-
Abcam antibodies for CD177
-
Cloud-Clone Corp. Antibodies for CD177
- Invitrogen Antibodies for CD177
- antibodies-online Antibodies for CD177: See all 106
- GeneTex CD177 antibody for CD177
-
Santa Cruz Biotechnology (SCBT) Antibodies for CD177
Protein Products
- R&D Systems Proteins and Enzymes for CD177
-
OriGene Purified Proteins for CD177
- Search Origene for MassSpec and Protein Over-expression Lysates for CD177
- Origene Custom Protein Services for CD177
- Sino Biological Recombinant Proteins for CD177
- Sino Biological Cell Lysates for CD177
-
Cloud-Clone Corp. Proteins for CD177
- antibodies-online Proteins for CD177: See all 14
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CD177
-
ProSci Proteins for CD177
-
Abcam proteins for CD177
Assay Products
- antibodies-online Kits for CD177: See all 4
No data available for DME Specific Peptides for CD177 Gene
Domains & Families for CD177 Gene
Gene Families for CD177 Gene
Protein Domains for CD177 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CD177 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CD177 Gene
Function for CD177 Gene
Molecular function for CD177 Gene
- UniProtKB/Swiss-Prot Induction:
- By CSF3 in resting granulocytes. Induced in patients with polycythemia vera (PV) and with essential thrombocythemia (ET).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for CD177 Gene
- MGI mutant phenotypes for CD177:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CD177:
Animal Models for CD177 Gene
- MGI Knock Outs for CD177:
-
- Cd177 tm1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD177
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CD177 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD177 gene
- Search ViGene Biosciences for CD177
CRISPR Products
-
OriGene CRISPR knockouts for CD177
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD177
- GenScript: Design CRISPR guide RNA sequences for CD177
miRNA for CD177 Gene
- miRTarBase miRNAs that target CD177
miRNA Products
- Search ViGene Biosciences for CD177
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CD177
- Browse OriGene Inhibitory RNA Products For CD177
-
ViGene Biosciences ready-to-package AAV shRNAs for CD177 gene
Clone Products
-
OriGene ORF clones in human for CD177
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CD177
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CD177
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD177
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CD177
-
ViGene Biosciences adenoviral particle packaged cDNA for CD177 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CD177 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD177 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CD177 Gene
Localization for CD177 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CD177 Gene
- Cell membrane; Lipid-anchor, GPI-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0031225 | anchored component of membrane | IEA | -- |
| GO:0035579 | specific granule membrane | TAS | -- |
| GO:0070062 | extracellular exosome | IDA | 23533145 |
Pathways & Interactions for CD177 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Formation of Fibrin Clot (Clotting Cascade) | ||
| 3 | Cell surface interactions at the vascular wall | ||
| 4 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
Pathways by source for CD177 Gene
7 Reactome pathways for CD177 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007596 | blood coagulation | TAS | -- |
| GO:0043312 | neutrophil degranulation | TAS | -- |
| GO:0050900 | leukocyte migration | TAS | -- |
No data available for SIGNOR curated interactions for CD177 Gene
Transcripts for CD177 Gene
mRNA/cDNA for CD177 Gene
- (3) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (66) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CD177
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD177
- GenScript: Design CRISPR guide RNA sequences for CD177
miRNA Products
- Search ViGene Biosciences for CD177
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CD177
- Browse OriGene Inhibitory RNA Products For CD177
-
ViGene Biosciences ready-to-package AAV shRNAs for CD177 gene
Clone Products
-
OriGene ORF clones in human for CD177
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CD177
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CD177
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD177
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for CD177 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CD177 Gene
This gene is overexpressed in Whole Blood (x47.7).
This gene is overexpressed in Nasal epithelium (45.5), Cervix (6.9), and Saliva (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CD177 Gene
NURSA nuclear receptor signaling pathways regulating expression of CD177 Gene:
CD177SOURCE GeneReport for Unigene cluster for CD177 Gene:
Hs.232165mRNA Expression by UniProt/SwissProt for CD177 Gene:
Q8N6Q3-CD177_HUMAN
Tissue specificity:
Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).
Evidence on tissue expression from TISSUES for CD177 Gene
- Intestine(4.8)
- Bone marrow(2.4)
- Blood(2.2)
- Lung(2.1)
Primer Products
-
OriGene qPCR primer pairs for CD177
-
OriGene qPCR primer pairs and template standards for CD177
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CD177 Gene
Orthologs for CD177 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CD177 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | LOC612424 34 |
|
||
| CD177 35 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Cd177 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cd177 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | CD177 35 |
|
OneToOne |
- Species where no ortholog for CD177 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CD177 Gene
(2) SIMAP similar genes for CD177 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for CD177 Gene
Variants for CD177 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for CD177 Gene
- CD177_HUMAN-Q8N6Q3
- There is a significant association between the variants Ala-3, Leu-251 and Thr-348 and a low expression of CD177 on neutrophils.
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000207945 | -- | 43,354,142(+) | TAGCA(A/G)CGTCT | intron-variant | |
| rs1000336340 | -- | 43,352,947(+) | TGATG(C/T)CCACT | upstream-variant-2KB | |
| rs1000383035 | -- | 43,361,832(+) | GAGGG(C/G)CTGGG | intron-variant | |
| rs1000678785 | -- | 43,353,164(+) | TATGG(A/C)GGGCC | upstream-variant-2KB | |
| rs1001220105 | -- | 43,362,242(+) | GAGGG(A/C)CTGGA | intron-variant, reference, synonymous-codon |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3591n100 | CNV | loss | 25217958 |
| dgv3603n100 | CNV | gain | 25217958 |
| dgv6502n54 | CNV | loss | 21841781 |
| esv2751795 | CNV | loss | 17911159 |
| esv2758763 | CNV | gain+loss | 17122850 |
| esv3644464 | CNV | loss | 21293372 |
| esv5616 | OTHER | inversion | 19470904 |
| esv8862 | OTHER | inversion | 19470904 |
| nsv1057657 | CNV | gain | 25217958 |
| nsv1057682 | CNV | loss | 25217958 |
| nsv1060280 | CNV | gain | 25217958 |
| nsv469666 | CNV | loss | 16826518 |
| nsv469787 | CNV | loss | 16826518 |
| nsv516973 | CNV | gain+loss | 19592680 |
| nsv526966 | CNV | loss | 19592680 |
| nsv828560 | CNV | gain | 20364138 |
| nsv828561 | CNV | loss | 20364138 |
| nsv963057 | CNV | duplication | 23825009 |
| nsv978908 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
50.6% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CD177 Gene
Disorders for CD177 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| polycythemia |
|
|
| essential thrombocythemia |
|
|
| deep leiomyoma |
|
|
| myelofibrosis |
|
|
| polycythemia vera, somatic |
|
Search CD177 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CD177
No data available for UniProtKB/Swiss-Prot and Genatlas for CD177 Gene
Publications for CD177 Gene
- Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms. (PMID: 12623849) Wolff J. … Bux J. (Blood 2003) 3 4 22 46 64
- Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. (PMID: 10753836) Temerinac S. … Pahl H.L. (Blood 2000) 2 3 4 22 64
- CD177 polymorphisms: correlation between high-frequency single nucleotide polymorphisms and neutrophil surface protein expression. (PMID: 14692971) Caruccio L. … Stroncek D. (Transfusion 2004) 3 4 22 64
- Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia. (PMID: 12377969) Teofili L. … Larocca L.M. (J. Clin. Oncol. 2002) 3 4 22 64
- Molecular basis of NB1 (HNA-2a, CD177) deficiency. (PMID: 12010833) Kissel K. … Bux J. (Blood 2002) 3 4 22 64
Products for CD177 Gene
- R&D Systems Antibodies for CD177 (CD177)
- R&D Systems Proteins and Enzymes for CD177
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CD177
- Search Origene for MassSpec and Protein Over-expression Lysates for CD177
- Origene Custom Protein Services for CD177
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CD177
- Browse OriGene Inhibitory RNA Products For CD177
- OriGene qPCR primer pairs and template standards for CD177
- OriGene qPCR primer pairs for CD177
- OriGene CRISPR knockouts for CD177
- OriGene ORF clones in human for CD177
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CD177
- GenScript: Next-day shipping cDNA ORF clone for CD177 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CD177
- GenScript Custom Assay Services for CD177
- GenScript Custom overexpressing Cell Line Services for CD177
- GenScript: Design CRISPR guide RNA sequences for CD177
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CD177
- Sino Biological Human cDNA Clone for CD177
- Sino Biological Recombinant Proteins for CD177
- Sino Biological Cell Lysates for CD177
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CD177
- Novus Biologicals proteins and lysates for CD177
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CD177
- Abcam proteins for CD177
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Cloud-Clone Corp. Antibodies for CD177
- Cloud-Clone Corp. Proteins for CD177
- Browse Assay Kits at Cloud-Clone Corp.
- Invitrogen Antibodies for CD177
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for CD177: See all 106
- antibodies-online Kits for CD177: See all 4
- antibodies-online Proteins for CD177: See all 14
- Search antibodies-online for peptides
- GeneTex CD177 antibody for CD177
- Search GeneTex for Proteins for CD177
- ViGene Biosciences adenoviral particle packaged cDNA for CD177 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CD177 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CD177 gene
- Search ViGene Biosciences for CD177
- Santa Cruz Biotechnology (SCBT) Antibodies for CD177
- Search Santa Cruz Biotechnology (SCBT) for CD177 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CD177
- Search for CD177 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CD177
- Horizon Cell Lines for CD177
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD177
- VectorBuilder custom plasmid, inducible vectors for CD177
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD177
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CD177 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer