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Aliases for CD164L2 Gene

Aliases for CD164L2 Gene

  • CD164 Molecule Like 2 2 3
  • CD164 Sialomucin-Like 2 2 5
  • EAPG6122 3
  • UNQ6122 3

External Ids for CD164L2 Gene

Previous GeneCards Identifiers for CD164L2 Gene

  • GC01M027578
  • GC01M027705
  • GC01M025961

Summaries for CD164L2 Gene

GeneCards Summary for CD164L2 Gene

CD164L2 (CD164 Molecule Like 2) is a Protein Coding gene. An important paralog of this gene is CD164.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD164L2 Gene

Genomics for CD164L2 Gene

Regulatory Elements for CD164L2 Gene

Promoters for CD164L2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CD164L2 on UCSC Golden Path with GeneCards custom track

Genomic Location for CD164L2 Gene

Chromosome:
1
Start:
27,379,100 bp from pter
End:
27,383,380 bp from pter
Size:
4,281 bases
Orientation:
Minus strand

Genomic View for CD164L2 Gene

Genes around CD164L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CD164L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CD164L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CD164L2 Gene

Proteins for CD164L2 Gene

  • Protein details for CD164L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UWJ8-C16L2_HUMAN
    Recommended name:
    CD164 sialomucin-like 2 protein
    Protein Accession:
    Q6UWJ8
    Secondary Accessions:
    • B2RPJ0
    • Q5JXD6

    Protein attributes for CD164L2 Gene

    Size:
    174 amino acids
    Molecular mass:
    18534 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CD164L2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CD164L2 Gene

Proteomics data for CD164L2 Gene at MOPED

Post-translational modifications for CD164L2 Gene

  • Glycosylation at Asn 71, Asn 103, and Thr 116
  • Modification sites at PhosphoSitePlus

Other Protein References for CD164L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CD164L2 Gene

Domains & Families for CD164L2 Gene

Protein Domains for CD164L2 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for CD164L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UWJ8

UniProtKB/Swiss-Prot:

C16L2_HUMAN :
  • Belongs to the CD164 family.
Family:
  • Belongs to the CD164 family.
genes like me logo Genes that share domains with CD164L2: view

No data available for Gene Families for CD164L2 Gene

Function for CD164L2 Gene

genes like me logo Genes that share phenotypes with CD164L2: view

Animal Model Products

  • Taconic Biosciences Mouse Models for CD164L2

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CD164L2 Gene

Localization for CD164L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CD164L2 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CD164L2 Gene COMPARTMENTS Subcellular localization image for CD164L2 gene
Compartment Confidence
extracellular 2
plasma membrane 2

No data available for Gene Ontology (GO) - Cellular Components for CD164L2 Gene

Pathways & Interactions for CD164L2 Gene

SuperPathways for CD164L2 Gene

No Data Available

Interacting Proteins for CD164L2 Gene

Gene Ontology (GO) - Biological Process for CD164L2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CD164L2 Gene

Drugs & Compounds for CD164L2 Gene

No Compound Related Data Available

Transcripts for CD164L2 Gene

mRNA/cDNA for CD164L2 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(18) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CD164L2 Gene

CD164 sialomucin-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CD164L2 Gene

No ASD Table

Relevant External Links for CD164L2 Gene

GeneLoc Exon Structure for
CD164L2
ECgene alternative splicing isoforms for
CD164L2

Expression for CD164L2 Gene

mRNA expression in normal human tissues for CD164L2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CD164L2 Gene

This gene is overexpressed in Esophagus - Mucosa (x10.9), Skin - Sun Exposed (Lower leg) (x6.3), Vagina (x5.3), Skin - Not Sun Exposed (Suprapubic) (x5.1), and Fallopian Tube (x4.2).

SOURCE GeneReport for Unigene cluster for CD164L2 Gene Hs.664836

genes like me logo Genes that share expression patterns with CD164L2: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CD164L2 Gene

Orthologs for CD164L2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CD164L2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia CD164L2 35
  • 87.28 (n)
  • 86.13 (a)
CD164L2 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cd164l2 35
  • 80.9 (n)
  • 81.87 (a)
Cd164l2 16
Cd164l2 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CD164L2 35
  • 99.61 (n)
  • 99.42 (a)
CD164L2 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100359977 35
  • 82.07 (n)
  • 80.7 (a)
cow
(Bos Taurus)
Mammalia CD164L2 36
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CD164L2 36
  • 54 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii cd164l2 35
  • 50.14 (n)
  • 40 (a)
cd164l2 36
  • 36 (a)
OneToOne
Species with no ortholog for CD164L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CD164L2 Gene

ENSEMBL:
Gene Tree for CD164L2 (if available)
TreeFam:
Gene Tree for CD164L2 (if available)

Paralogs for CD164L2 Gene

Paralogs for CD164L2 Gene

(1) SIMAP similar genes for CD164L2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CD164L2: view

Variants for CD164L2 Gene

Sequence variations from dbSNP and Humsavar for CD164L2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2504779 - 27,382,530(+) CCACA(C/T)GCAGC nc-transcript-variant, reference, missense
rs734725 -- 27,383,368(+) GGCCA(G/T)GTGGG upstream-variant-2KB
rs743044 -- 27,384,170(-) GGAAT(A/G)TCCAG upstream-variant-2KB
rs2273269 -- 27,379,425(+) CCCCC(C/T)GCTTA intron-variant, utr-variant-3-prime
rs2504777 -- 27,380,011(+) GAGGT(A/G)AGCTG intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CD164L2 Gene

Variant ID Type Subtype PubMed ID
nsv526051 CNV Gain 19592680
dgv203n71 CNV Loss 21882294
nsv516766 CNV Loss 19592680
esv1006916 CNV Deletion 20482838

Variation tolerance for CD164L2 Gene

Residual Variation Intolerance Score: 57.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.96; 59.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CD164L2 Gene

HapMap Linkage Disequilibrium report
CD164L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD164L2 Gene

Disorders for CD164L2 Gene

Relevant External Links for CD164L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CD164L2

No disorders were found for CD164L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CD164L2 Gene

Publications for CD164L2 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A common genetic variant of FCN3/CD164L2 is associated with essential hypertension in a Chinese population. (PMID: 22471352) Lu J. … Jia W. (Clin. Exp. Hypertens. 2012) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3

Products for CD164L2 Gene

Sources for CD164L2 Gene

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