Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CD163L1 Gene

protein-coding   GIFtS: 48
GCID: GC12M007507

CD163 Molecule-Like 1

(Previous name: CD163 antigen-like 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CD163 Molecule-Like 11 2     CD163 Antigen B2
CD163 Antigen-Like 11 2 3     Scavenger Receptor Cysteine-Rich Type 1 Protein M1602
CD163B2 3 5     CD163b Antigen3
M1602 3 5     CD164L15

External Ids:    HGNC: 303751   Entrez Gene: 2833162   Ensembl: ENSG000001776757   OMIM: 6060795   UniProtKB: Q9NR163   

Export aliases for CD163L1 gene to outside databases

Previous GC identifer: GC12M007399


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CD163L1 Gene:
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are
secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family
is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding.
The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively
spliced transcript variants encoding different isoforms have been described but their full-length nature has not
been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for CD163L1 Gene: 
CD163L1 (CD163 molecule-like 1) is a protein-coding gene. Diseases associated with CD163L1 include hepatitis b, and hepatitis. GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is LOXL2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CD163L1 gene promoter:
         MZF-1   FOXO1a   Evi-1   GATA-1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCD163L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CD163L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD163L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.3   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.31

CD163L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CD163L1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M007507:  view genomic region     (about GC identifiers)

Start:
7,499,281 bp from pter      End:
7,632,493 bp from pter
Size:
133,213 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: C163B_HUMAN, Q9NR16 (See protein sequence)
Recommended Name: Scavenger receptor cysteine-rich type 1 protein M160 precursor  
Size: 1453 amino acids; 159239 Da
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 2: Cell membrane; Single-pass type I membrane protein (Probable)
Subcellular location: Isoform 3: Secreted (Probable)
Secondary accessions: B4E0G7 C9JHR7 E7EVK4 Q2M3B7 Q6UWC2
Alternative splicing: 4 isoforms:  Q9NR16-1   Q9NR16-2   Q9NR16-3   Q9NR16-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CD163L1: NX_Q9NR16

Explore proteomics data for CD163L1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NR16

  • CD163L1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CD163L1 Protein Expression
    REFSEQ proteins: NP_777601.2  
    ENSEMBL proteins: 
     ENSP00000438217   ENSP00000315945   ENSP00000393474   ENSP00000443004   ENSP00000439921  
     ENSP00000442328   ENSP00000379871  

    Human Recombinant Protein Products for CD163L1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for CD163L1
    GenScript Custom Purified and Recombinant Proteins Services for CD163L1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CD163L1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    CD163L1 for ontologies           About GeneDecksing



    CD163L1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CD163L1
    OriGene Custom Antibody Services for CD163L1
    GenScript Custom Superior Antibodies Services for CD163L1
    Novus Biologicals CD163L1 Antibody
    Abcam antibodies for CD163L1
    Cloud-Clone Corp. Antibodies for CD163L1 
    Search ThermoFisher Antibodies for CD163L1
    LSBio Antibodies in human, mouse, rat for CD163L1 

    Assay Products for CD163L1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CD163L1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CD163L1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CD163L1 
    Cloud-Clone Corp. CLIAs for CD163L1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001190 Srcr_rcpt
     IPR017448 Srcr_rcpt-rel

    Graphical View of Domain Structure for InterPro Entry Q9NR16

    ProtoNet protein and cluster: Q9NR16

    UniProtKB/Swiss-Prot: C163B_HUMAN, Q9NR16
    Similarity: Contains 12 SRCR domains


    CD163L1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005044scavenger receptor activity IEA--
         
    CD163L1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CD163L1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD163L1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CD163L1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CD163L1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD163L1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CD163L1
    SwitchGear 3'UTR luciferase reporter plasmidCD163L1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD163L1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD163L1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CD163L1
    Sirion Biotech Customized adenovirus for overexpression of CD163L1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CD163L1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CD163L1 (NM_174941)
    Sino Biological Human cDNA Clone for CD163L1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD163L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD163L1
    Sirion Biotech Customized lentivirus for stable overexpression of CD163L1 
                         Customized lentivirus expression plasmids for stable overexpression of CD163L1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CD163L1
    Search LifeMap BioReagents cell lines for CD163L1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD163L1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CD163L1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CD163L1 (C163B)

    Search CenterWatch for drugs/clinical trials and news about CD163L1 / C163B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CD163L1 gene: 
    NM_174941.4  

    Unigene Cluster for CD163L1:

    CD163 molecule-like 1
    Hs.631727  [show with all ESTs]
    Unigene Representative Sequence: AK303372
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000539726 ENST00000542055 ENST00000543841 ENST00000313599(uc001qsy.3)
    ENST00000416109(uc010sge.2) ENST00000546182 ENST00000545597 ENST00000544331
    ENST00000545926 ENST00000543276 ENST00000396630
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CD163L1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CD163L1
    SwitchGear 3'UTR luciferase reporter plasmidCD163L1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CD163L1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD163L1
    Clone
    Products:
         
    OriGene clones in human, mouse for CD163L1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CD163L1 (NM_174941)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CD163L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD163L1
    Sirion Biotech Customized lentivirus for stable overexpression of CD163L1 
                         Customized lentivirus expression plasmids for stable overexpression of CD163L1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CD163L1
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD163L1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD163L1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD163L1

    Additional mRNA sequence: 

    AF264014.1 AK058038.1 AK303372.1 BC104962.1 BC104964.1 GQ397482.1 

    3 DOTS entries:

    DT.208793  DT.100756478  DT.100705440 

    24/38 AceView cDNA sequences (see all 38):

    NM_174941 AL529439 BF792807 BQ024006 BQ882211 AA582301 W42792 BQ776070 
    AK058038 BX092497 AI288981 W42886 AI738432 BG570972 AI278132 AI090561 
    BV177491 AF264014 BV167606 AI095706 BX355217 AI609329 BF132072 CA428959 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CD163L1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                -                                                                                                   
    SP2:                                            -                                                                                       


    ECgene alternative splicing isoforms for CD163L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CD163L1 expression in normal human tissues (normalized intensities)      CD163L1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTGTGAAGA
    CD163L1 Expression
    About this image


    CD163L1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Adrenal Gland (Endocrine System)    fully expand to see all 2 entries
             adrenal gland ; glandular cells   
             adrenal cortex   
     
     Uncategorized (Uncategorized)    fully expand to see all 2 entries
             PureStem progenitor RP1-MV2-16
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 2 entries
             stomach, upper ; glandular cells   

    See CD163L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CD163L1

    SOURCE GeneReport for Unigene cluster: Hs.631727

    UniProtKB/Swiss-Prot: C163B_HUMAN, Q9NR16
    Tissue specificity: Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly
    expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is
    restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen

        SABiosciences Custom PCR Arrays for CD163L1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CD163L1
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CD163L1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD163L1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD163L1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD163L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CD163L1 gene from 4/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia --
    --
    40(a)
    possible ortholog
    JH373805.1(3580-19647)
    chicken
    (Gallus gallus)
    Aves --
    --
    (see all 6)
    --
    49(a)
    45(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    LGE64(519298-531181)
    LGE64(554374-570805)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    34(a)
    32(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    GL344260.1(27472-41436)
    GL343253.1(1419716-1436678)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005364801 deleted in malignant brain tumors 1 protein-like 51.62(n)
    38.98(a)
      100536480  XM_003198251.1  XP_003198299.1 


    ENSEMBL Gene Tree for CD163L1 (if available)
    TreeFam Gene Tree for CD163L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CD163L1 gene
    LOXL22  CD62  LOXL42  CD1632  LOXL32  SSC5D2  PRSS122  CD5L2  
    LOX2  SRCRB4D2  LOXL12  DMBT12  
    7 SIMAP similar genes for CD163L1 using alignment to 6 protein entries:     C163B_HUMAN (see all proteins):
    CD163    SSC5D    LOXL2    LGALS3BP    CD5L    CD6
    DMBT1

    CD163L1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1861 SNPs in CD163L1 are shown (see all 1861)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0598104
    ----see VAR_0598102 L M mis40--------
    rs770439481,2
    C,F--7391748(+) AATTAC/TACTAA 1 -- ds50011Minor allele frequency- T:0.03EA 120
    rs1416549911,2
    C--7391764(+) ACTACA/GAGAAC 1 -- ds50010--------
    rs1155179441,2
    --7391959(+) AGATCA/GGGGTG 1 -- ds50010--------
    rs1911062121,2
    C--7392101(+) CATGAA/GGGCTT 1 -- ds50010--------
    rs1827645421,2
    --7392121(+) GACATA/GATTAC 1 -- ds50010--------
    rs64881771,2
    C,F,H--7392136(+) CCAAAG/ACTCCA 1 -- ds500116Minor allele frequency- A:0.01NS NA WA CSA EA 918
    rs1505767231,2
    C--7392330(+) TTTTCC/TATAGG 1 -- ut310--------
    rs11297281,2
    C,F,A,H--7392332(-) GCCCTA/GTGGAA 1 -- ut31 ese318Minor allele frequency- G:0.23NS EA NA CSA WA 2341
    rs88151,2
    C,F,H--7392401(+) GTTGAT/GCTGAA 1 -- ut3122Minor allele frequency- G:0.13NS EA NA 2540

    HapMap Linkage Disequilibrium report for CD163L1 (7499281 - 7632493 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CD163L1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2745488CNV Deletion23290073
    esv1408895CNV Insertion17803354
    nsv595CNV Insertion18451855
    nsv594CNV Loss18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CD163L1
    DNA2.0 Custom Variant and Variant Library Synthesis for CD163L1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606079    OMIM disorders: --

    2 diseases for CD163L1:    About MalaCards
    hepatitis b    hepatitis


    CD163L1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CD163L1
    Human Genome Epidemiology (HuGE) Navigator: CD163L1 (2 documents)

    Export disorders for CD163L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CD163L1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with CD163L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of a novel scavenger receptor cysteine-rich type I transmembrane molecule (M160) expressed by human macrophages. (PubMed id 11086079)1, 2, 3 Gronlund J....Holmskov U. (2000)
    2. Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridization and somatic cell hybrid analysis. (PubMed id 11124526)1, 3, 9 Stover C.M....Holmskov U. (2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus. (PubMed id 20032174)1, 2 Van Gorp H....Nauwynck H.J. (2009)
    5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    8. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 283316 HGNC: 30375 AceView: M160 Ensembl:ENSG00000177675 euGenes: HUgn283316
    ECgene: CD163L1 H-InvDB: CD163L1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CD163L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CD163L1 gene:
    Search GeneIP for patents involving CD163L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CD163L1   OriGene RNAi products in human, mouse, rat for CD163L1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CD163L1  
     OriGene qSTAR qPCR primer pairs in human, mouse for CD163L1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CD163L1   OriGene Custom Protein Services for CD163L1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CD163L1
     QIAGEN SeqTarget long-range PCR primers for resequencing CD163L1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CD163L1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CD163L1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CD163L1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CD163L1
     GenScript Custom Purified and Recombinant Proteins Services for CD163L1 GenScript cDNA clones with any tag delivered in your preferred vector for CD163L1
     GenScript Custom Assay Services for CD163L1 GenScript Custom Superior Antibodies Services for CD163L1
     GenScript Custom overexpressing Cell Line Services for CD163L1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CD163L1 promoter
     Search Chromatin IP Primers for CD163L1
     RT2 qPCR Primer Assay in human, mouse / rat CD163L1
     Search GNC Networks for CD163L1
     SABiosciences Custom PCR Arrays for CD163L1
     Search Tocris compounds for CD163L1 (C163B)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for CD163L1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CD163L1 antibodies
     Antibodies for CD163L1
     See all of Abcam's Antibodies, Kits and Proteins for CD163L1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for CD163L1
     Antibodies for CD163L1
     ELISAs for CD163L1
     CLIAs for CD163L1
     Search LifeMap BioReagents cell lines for CD163L1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CD163L1
     SwitchGear 3'UTR luciferase reporter plasmids for CD163L1
     SwitchGear Promoter luciferase reporter plasmids for CD163L1
     Search ThermoFisher Antibodies for CD163L1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CD163L1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for CD163L1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CD163L1
    Customized:
     lentivirus for stable overexpression of CD163L1
     lentivirus expression plasmids for stable overexpression of CD163L1
     adenovirus for overexpression of CD163L1
     LSBio Antibodies in human, mouse, rat for CD163L1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CD163L1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4