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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCZ1 Gene

protein-coding   GIFtS: 44
GCID: GC07P005938

CCZ1 vacuolar protein trafficking and biogenesis associated...

(Previous name: chromosome 7 open reading frame 28A )
(Previous symbol: C7orf28A)
 Explore 1 disease affiliated with
CCZ1 via our new
 Human Malady Compendium 
Biological research products
for CCZ1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
CCZ1 Vacuolar Protein Trafficking And Biogenesis Associated Homolog (S.
Cerevisiae)1 2
     Chromosome 7 Open Reading Frame 28A1
C7orf28A1 2 3     H_DJ1163J12.22
CCZ1A1 2     H_NH0577018.22
CGI-431     Vacuolar Fusion Protein CCZ1 Homolog2

External Ids:    HGNC: 216911   Entrez Gene: 516222   Ensembl: ENSG000001226747   UniProtKB: P867913   

Export aliases for CCZ1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CCZ1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CCZ1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCZ1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCZ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1   Ensembl cytogenetic band:  7p22.1   HGNC cytogenetic band: 7p22.2

CCZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCZ1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P005938:  view genomic region     (about GC identifiers)

Start:
5,938,341 bp from pter      End:
5,965,605 bp from pter
Size:
27,265 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 5,984,686-6,011,950     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CCZ1_HUMAN, P86791 (See protein sequence)
Recommended Name: Vacuolar fusion protein CCZ1 homolog  
Size: 482 amino acids; 55866 Da
Subcellular location: Lysosome membrane
Secondary accessions: A2RU45 O95766 Q9UG65 Q9Y359

Explore the universe of human proteins at neXtProt for CCZ1: NX_P86791

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P86791

  • CCZ1 Protein expression data from MOPED and PaxDb:    About this image 
    CCZ1 Protein Expression
    REFSEQ proteins: NP_056437.4  
    ENSEMBL proteins: 
     ENSP00000325681   ENSP00000444661  

    Human Recombinant Protein Products for CCZ1: 
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    OriGene Custom Protein Services for CCZ1 
    GenScript Custom Purified and Recombinant Proteins Services for CCZ1
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CCZ1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IEA--

    CCZ1 for ontologies           About GeneDecksing



    CCZ1 Antibody Products: 
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    ThermoFisher Antibody for CCZ1

    Assay Products for CCZ1: 
    Browse Kits and Assays available from EMD Millipore
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    Uscn ELISAs and CLIAs for CCZ1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCZ1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR013176 DUF1712_fun

    Graphical View of Domain Structure for InterPro Entry P86791

    ProtoNet protein and cluster: P86791

    UniProtKB/Swiss-Prot: CCZ1_HUMAN, P86791
    Similarity: Belongs to the CCZ1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CCZ1 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: CCZ1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CCZ1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCZ1:
    hsa-miR-137
    SwitchGear 3'UTR luciferase reporter plasmidCCZ1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCZ1 (see all 4)
    OriGene shRNA RFP: CCZ1
    OriGene siRNA: CCZ1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCZ1
    Sirion Biotech Custom design and validation of potent shRNA sequences against CCZ1 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CCZ1
    Sirion Biotech Customized adenovirus for overexpression of CCZ1 
    Sirion Biotech Customized adenovirus for potent knockdown of CCZ1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCZ1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCZ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CCZ1 (NM_015622)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCZ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCZ1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CCZ1
    Search LifeMap BioReagents cell lines for CCZ1
    Sirion Biotech Customized stable knockdown cell line services for CCZ1 
    Sirion Biotech Customized inducible knockdown cell line services for CCZ1
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    Sirion Biotech Customized inducible overexpressing cell line services for CCZ1

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCZ1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCZ1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for CCZ1 (P867913 ENSP000003256814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FYCO1Q9BQS83, ENSP000002961374I2D: score=3 STRING: ENSP00000296137
    DEDDO756183I2D: score=1 
    MON1AQ86VX93I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCZ1
    Search CenterWatch for drugs/clinical trials and news about CCZ1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCZ1 gene: 
    NM_015622.5  

    Unigene Cluster for CCZ1:

    CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
    Hs.530000  [show with all ESTs]
    Unigene Representative Sequence: BC067810
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000461592 ENST00000325974(uc003spf.3) ENST00000478672 ENST00000483394
    ENST00000474507 ENST00000496860 ENST00000537980

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: CCZ1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CCZ1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCZ1:
    hsa-miR-137
    SwitchGear 3'UTR luciferase reporter plasmidCCZ1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCZ1 (see all 4)
    OriGene shRNA RFP: CCZ1
    OriGene siRNA: CCZ1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCZ1
    Sirion Biotech Custom design and validation of potent shRNA sequences against CCZ1 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCZ1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCZ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CCZ1 (NM_015622)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCZ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCZ1 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCZ1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCZ1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCZ1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCZ1

    Additional cDNA sequence: 

    BC067810.1 BC132749.1 BC132751.1 

    20 DOTS entries:

    DT.97856263  DT.100890363  DT.100890368  DT.95258690  DT.121128018  DT.121095974  DT.121128037  DT.121128051 
    DT.92072227  DT.100890383  DT.121096001  DT.121128015  DT.121128041  DT.91748555  DT.91927928  DT.121128033 
    DT.75159455  DT.92072238  DT.92072242  DT.95258711 

    24/300 AceView cDNA sequences (see all 300):

    AI208759 AI309982 AA379841 BQ889481 BQ028327 AL554597 CR590431 CR595861 
    BG113949 BQ938093 BU684846 AA835425 BM992989 AA811971 BE874607 BQ063050 
    BM761646 BG177605 CR597206 BP341272 BM826046 BE294404 AJ713879 AW189559 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CCZ1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
    SP1:                                                      
    SP2:                    -                       -         


    ECgene alternative splicing isoforms for CCZ1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCZ1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAAGTTAGTG
    CCZ1 Expression
    About this image

    CCZ1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbStylopod Synovial JointInterzone CellsCartilage
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    BoneZeugopod Long BoneBone
    LimbAutopodLimb
    LimbStylopod Synovial JointLimb
    Skeletal MuscleExtraocular MusclesSkeletal Muscle
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CCZ1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCZ1

    SOURCE GeneReport for Unigene cluster: Hs.530000
        SABiosciences Custom PCR Arrays for CCZ1
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCZ1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCZ1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCZ1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCZ1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCZ1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CCZ1 gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CCZ11 CCZ1 vacuolar protein trafficking and biogenesis associated more 83.23(n)
    93.87(a)
      416433  NM_001006158.1  NP_001006158.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    89(a)
    1 → many
    GL343507.1(304239-323921)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF783084.12   -- 76.31(n)    CF783084.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ccz11 CCZ1 vacuolar protein trafficking and biogenesis associated more 76.02(n)
    84.37(a)
      393103  NM_200134.1  NP_956428.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG149801 CG14980 46.25(n)
    31.4(a)
      38455  NM_139578.3  NP_647835.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ccz-11 Protein CCZ-1 43.93(n)
    29.78(a)
      186547  NM_073986.2  NP_506387.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G809101 hypothetical protein 42.96(n)
    26.1(a)
      844431  NM_106739.3  NP_178206.1 
    rice
    (Oryza sativa)
    Liliopsida Os08g04273001 hypothetical protein 39.87(n)
    25.61(a)
      4345617  NM_001068377.1  NP_001061842.1 


    ENSEMBL Gene Tree for CCZ1 (if available)
    TreeFam Gene Tree for CCZ1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCZ1 gene
    CCZ1B1 2  
    2 SIMAP similar genes for CCZ1 using alignment to 1 protein entry:     CCZ1_HUMAN:
    CCZ1B    DKFZp586I1023

    CCZ1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/533 NCBI SNPs in CCZ1 are shown (see all 533    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1489933371,2
    --5936388(+) AGTGTA/TGTGGT 1 -- us2k10--------
    rs1842321661,2
    --5936392(+) TAGTGC/GTGCAA 1 -- us2k10--------
    rs1871505451,2
    --5936428(+) ACTGGC/GTTCAA 1 -- us2k10--------
    rs349827861,2
    C--5936468(+) AGCTGA/GAACCA 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs580511191,2
    --5936529(+) GGGCTG/TGTCTG 1 -- us2k10--------
    rs1178083471,2
    F--5936605(+) CCACCG/ATGGCT 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1921214971,2
    --5936610(+) GTGGCC/TAGCCT 1 -- us2k10--------
    rs1999155271,2
    --5936622(+) GTTTA-/TTTCTA 1 -- us2k10--------
    rs1834408401,2
    --5936702(+) CTACAA/CTCCCA 1 -- us2k10--------
    rs1885511201,2
    --5936727(+) CAAGGC/TCAGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCZ1 (5938341 - 5965605 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CCZ1: --

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCZ1
    DNA2.0 Custom Variant and Variant Library Synthesis for CCZ1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCZ1 for disorders           About GeneDecksing

    1 disease for CCZ1:    About MalaCards
    hermansky-pudlak syndrome


    Export disorders for CCZ1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCZ1 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with CCZ1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. (PubMed id 20305638)1, 3 Kinchen J.M. and Ravichandran K.S. (2010)
    3. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)1, 2 Cantin G.T....Yates J.R. III (2008)
    4. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)1, 2 Dephoure N.... Gygi S.P. (2008)
    5. Integral and associated lysosomal membrane proteins. (PubMed id 17897319)1, 2 Schroeder B.... Hasilik A. (2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51622 HGNC: 21691 AceView: C7orf28A Ensembl:ENSG00000122674 euGenes: HUgn51622
    ECgene: CCZ1 H-InvDB: CCZ1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCZ1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCZ1 gene:
    Search GeneIP for patents involving CCZ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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     EMD Millipore Custom Antibody & Bulk Services
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     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
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     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for CCZ1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCZ1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCZ1  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for CCZ1   OriGene 3'-UTR Clone for CCZ1  
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     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CCZ1   OriGene Custom Protein Services for CCZ1  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCZ1
     Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCZ1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCZ1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCZ1
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     GenScript Custom Purified and Recombinant Proteins Services for CCZ1 GenScript cDNA clones with any tag delivered in your preferred vector for CCZ1
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     GenScript Custom overexpressing Cell Line Services for CCZ1 CloneReady with Over 120,000 Genes
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     Search for Antibodies & Assays

     Search Regulatory tfbs for CCZ1
     Search Chromatin IP Primers for CCZ1
     RT2 qPCR Primer Assay in human, mouse / rat CCZ1
     Search GNC Networks for CCZ1
     SABiosciences Custom PCR Arrays for CCZ1
     Search Tocris compounds for CCZ1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
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     See all of Abcam's Antibodies, Kits and Proteins for CCZ1
     Custom Antibody / Protein Production Service
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     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     CCZ1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for CCZ1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCZ1
     SwitchGear 3'UTR luciferase reporter plasmids for CCZ1
     SwitchGear Promoter luciferase reporter plasmids for CCZ1
     ThermoFisher Antibody for CCZ1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCZ1
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CCZ1
    Sirion Biotech Customized:
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     inducible knockdown cell line services for CCZ1
     design and validation of potent shRNA sequences against CCZ1
     adenovirus for potent knockdown of CCZ1
     adenovirus for overexpression of CCZ1
     stable overexpressing cell line services for CCZ1
     inducible overexpressing cell line services for CCZ1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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