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CCT6B Gene

protein-coding   GIFtS: 59
GCID: GC17M033254

Chaperonin Containing TCP1, Subunit 6B (Zeta 2)

  Search for CCT6B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chaperonin Containing TCP1, Subunit 6B (Zeta 2)1 2     TSA3032
Testis-Specific Protein TSA3032 3     T-Complex Protein 1 Subunit Zeta-22
Testis-Specific Tcp202 3     T-Complex Protein 1, Zeta-2 Subunit2
CCT-zeta-22 3     CCT-zeta-like3
TCP-1-zeta-22 3     TCP-1-zeta-like3
CCTZ-22     CCTZ25
Cctz22     

External Ids:    HGNC: 16211   Entrez Gene: 106932   Ensembl: ENSG000001321417   OMIM: 6107305   UniProtKB: Q925263   

Export aliases for CCT6B gene to outside databases

Previous GC identifers: GC17M033024 GC17M035290 GC17M033400 GC17M030279 GC17M029439


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CCT6B Gene:
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also
known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing
eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an
ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional
splice variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2010)

GeneCards Summary for CCT6B Gene:
CCT6B (chaperonin containing TCP1, subunit 6B (zeta 2)) is a protein-coding gene. GO annotations related to this gene include protein transporter activity and unfolded protein binding. An important paralog of this gene is CCT6A.

UniProtKB/Swiss-Prot: TCPW_HUMAN, Q92526
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in
vitro, in the folding of actin and tubulin (By similarity)

Gene Wiki entry for CCT6B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCT6B gene promoter:
         AML1a   p53   ATF-2   XBP-1   CUTL1   AP-2gamma   FOXJ2 (long isoform)   FOXJ2   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCT6B promoter sequence
   Search Chromatin IP Primers for CCT6B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCT6B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q

CCT6B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCT6B gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M033254:  view genomic region     (about GC identifiers)

Start:
33,254,878 bp from pter      End:
33,308,097 bp from pter
Size:
53,220 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TCPW_HUMAN, Q92526 (See protein sequence)
Recommended Name: T-complex protein 1 subunit zeta-2  
Size: 530 amino acids; 57821 Da
Subunit: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter
Secondary accessions: B4DX20 B4DYB0 Q8TC34
Alternative splicing: 3 isoforms:  Q92526-1   Q92526-2   Q92526-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCT6B: NX_Q92526

Explore proteomics data for CCT6B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys41
  • Modification sites at PhosphoSitePlus

  • See CCT6B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001180458.1  NP_001180459.1  NP_006575.2  

    ENSEMBL proteins: 
     ENSP00000398044   ENSP00000327191   ENSP00000400917   ENSP00000462020  

    CCT6B Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for CCT6B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CHAP: Heat Shock Proteins / Chaperonins

    Selected InterPro protein domains (see all 7):
     IPR017998 Chaperone_TCP-1
     IPR002194 Chaperonin_TCP-1_CS
     IPR027410 TCP-1-like_intermed
     IPR027409 GroEL-like_apical_dom
     IPR002423 Cpn60/TCP-1

    Graphical View of Domain Structure for InterPro Entry Q92526

    ProtoNet protein and cluster: Q92526

    2 Blocks protein domains:
    IPB001844 Chaperonin Cpn60
    IPB002194 Chaperonin TCP-1


    UniProtKB/Swiss-Prot: TCPW_HUMAN, Q92526
    Similarity: Belongs to the TCP-1 chaperonin family


    Find genes that share domains with CCT6B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCPW_HUMAN, Q92526
    Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in
    vitro, in the folding of actin and tubulin (By similarity)

         Genatlas biochemistry entry for CCT6B:
    chaperonin containing TCP1 (T complex protein 1),subunit 6B (zeta 2),testis specific,cytoplasmic,S cerevisiae
    TCP20 homolog,TF55/TCP-1 family

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
    GO:0008565protein transporter activity TAS8812458
    GO:0051082unfolded protein binding IEA--
         
    Find genes that share ontologies with CCT6B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CCT6B:
     Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCT6B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCT6B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCT6B

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCT6B:
    hsa-mir-15a-5p (MIRT051329), hsa-mir-16-5p (MIRT031676)

    Block miRNA regulation of human, mouse, rat CCT6B using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CCT6B:
    hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidCCT6B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CCT6B

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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCT6B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCPW_HUMAN, Q92526: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    mitochondrion2
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005832chaperonin-containing T-complex IEA--

    Find genes that share ontologies with CCT6B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CCT6B About    
    See pathways by source

    SuperPathContained pathways About
    1Cell cycle Role of APC in cell cycle regulation
    Cell cycle Role of APC in cell cycle regulation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for CCT6B
        Cell cycle Role of APC in cell cycle regulation


        Pathway & Disease-focused RT2 Profiler PCR Array including CCT6B: 
              Heat Shock Proteins & Chaperones in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for CCT6B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CCT6B (Q925263 ENSP000003271914) via UniProtKB, MINT, STRING, and/or I2D (see all 137)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MOB4Q9Y3A33, ENSP000003157024I2D: score=1 STRING: ENSP00000315702
    STRNO438153, ENSP000002639184I2D: score=1 STRING: ENSP00000263918
    PPP2R2DQ66LE63I2D: score=1 
    FBXW8ENSP000003106864STRING: ENSP00000310686
    CCT2ENSP000002993004STRING: ENSP00000299300
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding IEA--
    GO:0007283spermatogenesis TAS8812458
    GO:0015031protein transport TAS8812458
    GO:0044267cellular protein metabolic process ----
    GO:0051131chaperone-mediated protein complex assembly TAS8812458

    Find genes that share ontologies with CCT6B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCT6B (TCPW)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CCT6B gene (3 alternative transcripts): 
    NM_001193529.1  NM_001193530.1  NM_006584.3  

    Unigene Cluster for CCT6B:

    Chaperonin containing TCP1, subunit 6B (zeta 2)
    Hs.73072  [show with all ESTs]
    Unigene Representative Sequence: NM_006584
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000421975 ENST00000314144(uc002hig.3 uc010ctg.3 uc010wcc.2)
    ENST00000577307 ENST00000436961 ENST00000585073
    miRNA
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    Block miRNA regulation of human, mouse, rat CCT6B using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CCT6B:
    hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidCCT6B 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCT6B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCT6B
    Primer
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    OriGene qPCR primer pairs and template standards for CCT6B
    OriGene qSTAR qPCR primer pairs in human, mouse for CCT6B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCT6B
      QuantiTect SYBR Green Assays in human, mouse, rat CCT6B
      QuantiFast Probe-based Assays in human, mouse, rat CCT6B

    Additional mRNA sequence: 

    AK225728.1 AK225729.1 AK301773.1 AK302344.1 BC026125.2 BC027591.1 D78333.1 

    7 DOTS entries:

    DT.111988  DT.95355332  DT.120964077  DT.100659452  DT.100653678  DT.120964075  DT.120964093 

    Selected AceView cDNA sequences (see all 73):

    CB129454 BP369048 AI015386 AI218246 BP370409 T35998 AA774541 BC026125 
    BP369578 BM856167 BP370404 BP368876 BP370455 D78333 BU069686 BP369744 
    BP369306 BI826129 AL044494 BM564077 BI827205 BI826707 BU069469 NM_006584 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CCT6B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                          
    SP2:                                                                                          
    SP3:                    -                                                                     


    ECgene alternative splicing isoforms for CCT6B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCT6B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGAGTCAAA
    CCT6B Expression
    About this image


    CCT6B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    CCT6B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCT6B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.73072

    UniProtKB/Swiss-Prot: TCPW_HUMAN, Q92526
    Tissue specificity: Testis specific

        Pathway & Disease-focused RT2 Profiler PCR Array including CCT6B: 
              Heat Shock Proteins & Chaperones in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCT6B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CCT6B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cct6b1 , 5 chaperonin containing Tcp1, subunit 6b (zeta)1, 5 83.96(n)1
    83.58(a)1
      11 (50.18 cM)5
    124671  NM_009839.21  NP_033969.21 
     827192505 
    chicken
    (Gallus gallus)
    Aves CCT66
    Gallus gallus chaperonin containing TCP1, subunit ...
    85(a)
    1 → many
    19(4884981-4891209)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.61432 Transcribed sequence with moderate similarity to protein refNP_001753.1 (H.sapiens) chaperonin containing TCP1, subunit 6A (zeta 1); chaperonin containing T-complex subunit 6 [Homo sapiens] less 78.16(n)    BX713522.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cct6a6
    chaperonin containing TCP1, subunit 6A (zeta 1)
    84(a)
    1 → many
    21(40509530-40528855) ENSDARG00000021252
    fruit fly
    (Drosophila melanogaster)
    Insecta CG82313 chaperonin ATPase 65(a)   13E14   --
    worm
    (Caenorhabditis elegans)
    Secernentea cct-63 Expression: embryo 61(a)   III(5925494-5926671)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CCT66
    Subunit of the cytosolic chaperonin Cct ring compl...
    54(a)
    1 → many
    IV(836421-838061) YDR188W


    ENSEMBL Gene Tree for CCT6B (if available)
    TreeFam Gene Tree for CCT6B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCT6B gene
    CCT6A2  
    7 SIMAP similar genes for CCT6B using alignment to 2 protein entries:     TCPW_HUMAN (see all proteins):
    CCT6A    CCT3    CCT5    CCT2    CCT4    TCP1
    CCT7

    Find genes that share paralogs with CCT6B           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CCT6B
    PGOHUM00000235126


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCT6B (see all 594)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1919710401,2
    --33254423(+) AATTAC/TTTCCC 3 -- ds50010--------
    rs1471347501,2
    C--33254602(+) AAACAA/CTGCAA 3 -- ds50010--------
    rs1834922521,2
    --33254620(+) CTACAC/TGCCAT 3 -- ds50010--------
    rs1859253921,2
    --33254798(+) TAAAGA/GTCCTA 3 -- ds50010--------
    rs20621011,2
    C,F,A,H--33254856(-) TTCCCC/TAAGAG 3 -- ds500118Minor allele frequency- T:0.24NS EA NA WA 2218
    rs1899956651,2
    --33254915(+) ATACCC/TTGATG 3 -- ut310--------
    rs759197961,2
    C,F--33254959(+) ATAAAC/TTGCAT 3 -- ut311Minor allele frequency- T:0.08EA 120
    rs1403200141,2
    C--33255025(+) GTGTAC/TTAAAT 3 -- ut310--------
    rs1148650321,2
    C,F--33255068(+) ATCATC/AATTTG 6 /* /L --3Minor allele frequency- A:0.00NA EU 6051
    rs1866085661,2
    C--33255087(+) CATCCC/TAGCTC 6 R G mis10--------

    HapMap Linkage Disequilibrium report for CCT6B (33254878 - 33308097 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CCT6B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv526685CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCT6B
    DNA2.0 Custom Variant and Variant Library Synthesis for CCT6B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610730    OMIM disorders: --


    Find genes that share disorders with CCT6B           About GenesLikeMe


    Export disorders for CCT6B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCT6B gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with CCT6B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method. (PubMed id 8812458)1, 2, 3, 9 Ozaki K.... Nakamura Y. (Genomics 1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1. (PubMed id 9013858)1, 3 Kubota H....Willison K.R. (FEBS Lett. 1997)
    4. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (PLoS Genet. 2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10693 HGNC: 1621 AceView: CCT6B Ensembl:ENSG00000132141 euGenes: HUgn10693
    ECgene: CCT6B H-InvDB: CCT6B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCT6B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CCT6B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCT6B gene:
    Search GeneIP for patents involving CCT6B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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