Aliases for CCT6A Gene
External Ids for CCT6A Gene
Previous HGNC Symbols for CCT6A Gene
Previous GeneCards Identifiers for CCT6A Gene
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]
GeneCards Summary for CCT6A Gene
CCT6A (Chaperonin Containing TCP1 Subunit 6A) is a Protein Coding gene. Among its related pathways are Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding and Chaperonin-mediated protein folding. GO annotations related to this gene include poly(A) RNA binding and unfolded protein binding. An important paralog of this gene is CCT6B.
UniProtKB/Swiss-Prot for CCT6A Gene
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.