CCT2 Gene
protein-coding GIFtS: 64
GCID: GC12P069979
|
|
chaperonin containing TCP1, subunit 2 (beta)
| |
Aliases
for CCT2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chaperonin Containing TCP1, Subunit 2 (Beta)1 2 | | PRO16332 | | CCTB2 3 5 | | Chaperonin Containing T-Complex Polypeptide 1, Beta Subunit2 | | 99D8.12 3 | | Chaperonin Containing T-Complex Polypeptide 1, Subunit 22 | | CCT-Beta1 | | T-Complex Protein 1 Subunit Beta2 | | TCP-1-Beta1 | | T-Complex Protein 1, Beta Subunit2 | | Cctb1 | | |
Export aliases for CCT2 gene to outside databasesPrevious GC identifers: GC12P069837 GC12P069695 GC12P068265 GC12P067028 |
Summaries
for CCT2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CCT2:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex(CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, eachcontaining eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded inan ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, Nov 2010)
UniProtKB/Swiss-Prot: TCPB_HUMAN, P78371Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex mayplay a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.Known to play a role, in vitro, in the folding of actin and tubulin
Gene Wiki entry for CCT2
|
Genomic Views
for CCT2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCT2 gene promoter:
Nkx3-1 Nkx3-1 v4 Nkx3-1 v1 Nkx2-5 POU3F2 LCR-F1 GATA-2 Nkx3-1 v2 FOXO4 Nkx3-1 v3
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCT2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCT2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q15 Ensembl cytogenetic band: 12q15 HGNC cytogenetic band: 12q14CCT2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P069979: view genomic region
(about GC identifiers)
Start:
|
69,979,114 bp from pter |
End:
|
69,995,357 bp from pter |
Size:
|
16,244 bases |
Orientation:
|
plus strand |
|
Proteins
for CCT2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TCPB_HUMAN, P78371 (See
protein sequence)Recommended Name: T-complex protein 1 subunit beta Size: 535 amino acids; 57488 Da
Subunit: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3,CCT4, CCT5 AND CCT8
Subcellular location: Cytoplasm
Secondary accessions: A8K402 B5BTY7 B7Z243 B7Z7K4 B7ZAT2 Q14D36 Q6IAT3Alternative splicing: 2 isoforms: P78371-1 P78371-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCT2: NX_P78371
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78371
CCT2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001185771.1 NP_006422.1
ENSEMBL proteins: ENSP00000299300 ENSP00000441847 ENSP00000450153 ENSP00000445471 Reactome Protein details: P78371
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
CCT2 for ontologies About GeneDecksing
CCT2 Antibody Products:
Assay Products for CCT2: |
Protein
Domains /
Families
for CCT2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCT2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P78371ProtoNet protein and cluster: P78371 2 Blocks protein families: IPB001844 Chaperonin Cpn60 IPB002194 Chaperonin TCP-1
UniProtKB/Swiss-Prot: TCPB_HUMAN, P78371Similarity: Belongs to the TCP-1 chaperonin family |
Function
for CCT2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TCPB_HUMAN, P78371Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex mayplay a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.Known to play a role, in vitro, in the folding of actin and tubulin Genatlas biochemistry entry for CCT2:chaperonin containing TCP1,subunit 2 (beta),cytosolic,TF55/TCP-1 family
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CCT2 (NM_006431) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCT2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCT2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCT2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CCT2 for ontologies About GeneDecksing
9 GenomeRNAi human phenotypes for CCT2:
|
Pathways & Interactions
for CCT2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of tubulin folding intermediates by CCT/TriC | | | 2 | Chaperonin-mediated protein folding | | | 3 | Cell cycle Role of APC in cell cycle regulation | | | 4 | Asparagine N-linked glycosylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CCT2
1  GeneGo (Thomson Reuters) Pathway for CCT2
5/8 
Reactome Pathways for CCT2 (see all 8)
CCT2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCT2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/1014 Interacting proteins for CCT2 (P783711, 2, 3 ENSP000002993004) via UniProtKB, MINT, STRING, and/or I2D (see all 1014)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006457 | protein folding |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- | | GO:0051084 | 'de novo' posttranslational protein folding |
TAS | -- | | GO:0051131 | chaperone-mediated protein complex assembly |
IMP | -- |
CCT2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CCT2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCT2
Search CenterWatch for drugs/clinical trials and news about CCT2 / TCPB
|
Transcripts
for CCT2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCT2 gene (2 alternative transcripts): NM_001198842.1 NM_006431.2 Unigene Cluster for CCT2: Chaperonin containing TCP1, subunit 2 (beta) Hs.189772 [show with all ESTs]Unigene Representative Sequence: NM_00119884215 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000299300(uc001svb.1) ENST00000546859 ENST00000549933 ENST00000550455
ENST00000550638 ENST00000551620 ENST00000551899 ENST00000544368 ENST00000550010
ENST00000543146(uc010stl.1) ENST00000550871 ENST00000548787 ENST00000546850
ENST00000553169 ENST00000550653
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CCT2 (NM_006431) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCT2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCT2 |
Additional cDNA sequence: AB451223.1 AB451346.1 AF026166.1 AF026293.1 AK290767.1 AK294307.1 AK297685.1 AK302157.1 AK316397.1 AK316408.1 BC113514.1 BC113516.1 BT019966.1 CR457071.1 24/27 DOTS entries (see all 27): DT.95366739 DT.95228517 DT.95366744 DT.100848412 DT.100848417 DT.95334620 DT.100848410 DT.100848405 DT.121194487 DT.121194472 DT.100848402 DT.121194449 DT.40225073 DT.40240828 DT.92459856 DT.95071193 DT.95366729 DT.95366749 DT.100731827 DT.100773145 DT.100848404 DT.121194503 DT.91652122 DT.95366737 24/826 AceView cDNA sequences (see all 826): BM761126 BF793118 H56329 BU192584 T34904 CB115756 BQ214339 BP336785 BM693765 BM854255 BM727275 BE780740 BP373478 CB119183 AI922596 BQ775057 BQ776117 BM788772 BU615323 AA022658 BG778111 CB158916 BP374633 BM999485
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CCT2 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|
|
| SP1: | | | | | - | | - | | | | | | - | | - | | | | - | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | - | | - | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | - | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCT2
|
Expression
for CCT2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTGACACA
About this image
See CCT2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCT2
SOURCE GeneReport for Unigene cluster: Hs.189772
SABiosciences Expression via Pathway-Focused PCR Arrays including CCT2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCT2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCT2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCT2 |
Orthologs
for CCT2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CCT2 gene from 9/42 species (see all 42) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CCT21 |
chaperonin containing TCP1, subunit 2 (beta) |
81.81(n)
93.08(a) |
|
417846 NM_001012533.1 NP_001012551.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CCT26 |
-- |
89(a) |
1 ↔ 1 |
GL343256.1(1643840-1653857) |
African clawed frog
(Xenopus laevis) |
Amphibia |
cct2-prov2 |
chaperonin subunit 2 (beta) |
78.98(n) |
|
BC042347.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cct22 |
chaperonin containing TCP1, subunit 2 (beta) |
74.36(n) |
|
192326 BC059558.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG70331 , 3 |
chaperone3
CG70331 |
71(a)3
62.78(n)1
71.43(a)1 |
|
8C83
318381 NM_132296.31 NP_572524.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
cct-21 |
Protein CCT-2 |
61.92(n)
66.98(a) |
|
174421 NM_171985.4 NP_741031.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CCT2(YIL142W)4
CCT21 |
Subunit beta of the cytosolic chaperonin Cct ring complex, more4
Cct2p1 |
61.89(n)1
65.97(a)1 |
|
9(83302-84885)4
8546641, 4 NP_012124.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G208901 |
TCP-1/cpn60 chaperonin family protein |
64.93(n)
68.34(a) |
|
832213 NM_122097.2 NP_197589.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.83832 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
75.95(n) |
|
AK059663.1 |
ENSEMBL Gene Tree for CCT2 (if available)
TreeFam Gene Tree for CCT2 (if available) |
Paralogs
for CCT2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCT2 gene
8 SIMAP similar genes for CCT2 using alignment to 3 protein entries: TCPB_HUMAN (see all proteins):CCT5 TCP1 CCT3 CCT4 CCT7 CCT6B
CCT6A CCT8
CCT2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CCT2
PGOHUM00000261534
|
Genomic Variants
for CCT2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCT2 (69979114 - 69995357 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCT2: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CCT2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCT2 for disorders About GeneDecksing
OMIM gene information: 605139
OMIM disorders: --
18  diseases for CCT2: About MalaCardscerebral cavernous malformations cavernous malformation cerebral cavernous malformations 3 cecum cancer
intrahepatic cholangiocarcinoma hepatocellular carcinoma cholangiocarcinoma cerebritis
colon carcinoma gastric cancer influenza carcinoma
breast cancer malaria prostatitis neuronitis
pancreatic cancer pancreatitis
1 disease from the University of Copenhagen DISEASES database for CCT2:Cecum cancer 1 Novoseek disease relationship for CCT2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hepatocellular carcinoma |
28 |
1 |
11795471 (1) |
Human Genome Epidemiology (HuGE) Navigator: CCT2 (2 documents)
Export disorders for CCT2 gene to outside databases
|
Publications
for CCT2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCT2 gene, integrated from 9 sources (see all 74):
(articles sorted by number of sources associating them with CCT2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. (PubMed id 9819444)1, 2, 3 Won K.-A.... Reed S.I. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. (PubMed id 14532270)1, 2 Imai Y.... Takahashi R. (2003)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin. (PubMed id 10748209)1, 9 Hynes G.M. and Willison K.R. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
|
External Searches for CCT2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCT2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCT2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCT2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCT2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCT2 gene:
Search GeneIP for patents involving CCT2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CCT2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for CCT2 | | OriGene shRNA RFP for CCT2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCT2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCT2 | | | OriGene Protein Over-expression Lysate for CCT2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCT2 | | OriGene 3'-UTR Clone for CCT2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCT2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CCT2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCT2 | | OriGene Custom Protein Services for CCT2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCT2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCT2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCT2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCT2 |
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| | Antibodies & Assays for CCT2 |
| | | | Search Tocris compounds for CCT2 |
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 | | | CCT2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCT2 |
|  |  |  | | | | ThermoFisher Antibody for CCT2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCT2 |
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