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CCSER2 Gene

protein-coding GIFtS: 42
GCID: GC10P086088

Coiled-Coil Serine-Rich Protein 2

(Previous names: KIAA1128, family with sequence similarity 190, member B)
(Previous symbols: KIAA1128, FAM190B)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Coiled-Coil Serine-Rich Protein 2¹ ² ³		Gcap14²
FAM190B¹ ² ³		bA486O22.1²
KIAA1128¹ ² ³		Protein FAM190B²
Family With Sequence Similarity 190, Member B¹ ²		Serine-Rich Coiled-Coil Domain-Containing Protein 2²
Protein GCAP14 Homolog² ³

External Ids:	HGNC: 29197¹	Entrez Gene: 54462²	Ensembl: ENSG00000107771⁷	UniProtKB: Q9H7U1³

Export aliases for CCSER2 gene to outside databases

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCSER2 Gene:

CCSER2 (coiled-coil serine-rich protein 2) is a protein-coding gene. Diseases associated with CCSER2 include schizophrenia, and alzheimer's disease. GO annotations related to this gene include microtubule binding.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000010.11 NT_030059.14 NC_018921.2

Regulatory elements:

Search for regulatory transcription factor binding sites for CCSER2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CCSER2 promoter sequence

Search Chromatin IP Primers for CCSER2

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCSER2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.1 Ensembl cytogenetic band: 10q23.1 HGNC cytogenetic band: 10q23.1

CCSER2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCSER2 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P086088: view genomic region (about GC identifiers)

Start:	86,088,342 bp from pter	End:	86,278,276 bp from pter
Size:	189,935 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CCSE2_HUMAN, Q9H7U1 (See protein sequence)

Recommended Name: Serine-rich coiled-coil domain-containing protein 2

Size: 834 amino acids; 93548 Da

Sequence caution: Sequence=AAG44473.1; Type=Frameshift; Positions=187, 240, 244; Sequence=AAH30528.1;

Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAI40902.1; Type=Erroneous gene model

prediction;

Secondary accessions: B4DQU9 B7WPE8 D3DWE2 Q8N6E9 Q9H2S0 Q9ULU1

Alternative splicing: 3 isoforms: Q9H7U1-1 Q9H7U1-2 Q9H7U1-3 (Ref.1 (BAG61061) sequence is in conflict in positions: 782:S->F, 881:M->I)

Explore the universe of human proteins at neXtProt for CCSER2: NX_Q9H7U1

Explore proteomics data for CCSER2 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See CCSER2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts):

NP_001271169.1 NP_001271170.1 NP_001271171.1 NP_001271172.1 NP_061872.2

ENSEMBL proteins:

ENSP00000353068 ENSP00000224756 ENSP00000361160 ENSP00000439944

CCSER2 Human Recombinant Protein Products:

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	Novus Biologicals CCSER2 Protein
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
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	Browse Proteins at Cloud-Clone Corp.

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	Novus Biologicals CCSER2 Antibodies
	Search for Antibodies for CCSER2 at Abcam
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	ThermoFisher Antibody for CCSER2
	LSBio Antibodies in human, mouse, rat for CCSER2

CCSER2 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for CCSER2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CCSER2
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q9H7U1

UniProtKB/Swiss-Prot: CCSE2_HUMAN, Q9H7U1

Similarity: Belongs to the CCSER family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008017	microtubule binding	IEA	--

CCSER2 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCSER2

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCSER2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCSER2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCSER2

miRNA Products:		miRTarBase miRNAs that target CCSER2: hsa-mir-335-5p (MIRT018535), hsa-mir-26b-5p (MIRT029906), hsa-mir-132-3p (MIRT021844)

		Block miRNA regulation of human, mouse, rat CCSER2 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate CCSER2
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Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CCSER2
		Predesigned siRNA for gene silencing in human, mouse, rat CCSER2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CCSER2

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCSER2

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015630	microtubule cytoskeleton	IEA	--

CCSER2 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for CCSER2
Interactions:

Search GeneGlobe Interaction Network for CCSER2

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for CCSER2 (Q9H7U1^{2, 3} ENSP00000224756⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 18)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GTF2H1	P32780²^,³, ENSP00000265963⁴	MINT-63669 I2D: score=5 STRING: ENSP00000265963
OFD1	O75665²^,³	MINT-63222 I2D: score=5
PSMD11	O00231²^,³	MINT-63038 I2D: score=5
MAP1LC3B	Q9GZQ8²^,³	MINT-8259639 I2D: score=2
STX1A	Q16623²^,³, ENSP00000222812⁴	MINT-64287 I2D: score=5 STRING: ENSP00000222812

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Gene Ontology (GO): 1 biological process term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001578	microtubule bundle formation	IEA	--

CCSER2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for CCSER2 (CCSE2)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CCSER2 gene (5 alternative transcripts):

NM_001284240.1 NM_001284241.1 NM_001284242.1 NM_001284243.1 NM_018999.3

Unigene Cluster for CCSER2:

Coiled-coil serine-rich protein 2

Hs.461988 [show with all ESTs]

Unigene Representative Sequence: NM_018999

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000359979(uc001kdg.1) ENST00000224756(uc001kdh.1 uc010qmd.1 uc001kdi.1 uc010qme.1)

ENST00000494144 ENST00000494586 ENST00000493409 ENST00000498300 ENST00000466105

ENST00000480006 ENST00000372088 ENST00000543283

miRNA Products:		Block miRNA regulation of human, mouse, rat CCSER2 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate CCSER2
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CCSER2
		Predesigned siRNA for gene silencing in human, mouse, rat CCSER2

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Primer Products:		OriGene qPCR primer pairs and template standards for CCSER2 OriGene qSTAR qPCR primer pairs in human, mouse for CCSER2
		Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat CCSER2
		QuantiTect SYBR Green Assays in human, mouse, rat CCSER2
		QuantiFast Probe-based Assays in human, mouse, rat CCSER2

Additional mRNA sequence:

AB032954.1 AF241785.1 AK024324.1 AK098675.1 AK294321.1 AK298966.1 BC020910.1 BC030528.1

BX640691.1 U90912.1

11 DOTS entries:

DT.415981 DT.95277659 DT.95277662 DT.100789582 DT.91759374 DT.100789581 DT.91759377 DT.95277661

DT.121212840 DT.121212898 DT.95110984

Selected AceView cDNA sequences (see all 53):

AA694185 AA662191 BI829315 AI927019 BP362870 BU632221 AI678126 BC030528

BP370871 AI001725 T39163 AA424126 AW027699 W77829 BF173466 BQ429698

AA424038 BP369764 AK024324 AL707865 BI772058 AA432090 AA446776 BU599757

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for CCSER2 About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	·	13c	·	13d
SP1:									-		-										-
SP2:																	-		-		-								-
SP3:																					-								-
SP4:																													-
SP5:

ECgene alternative splicing isoforms for CCSER2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CCSER2 expression in normal human tissues (normalized intensities) CCSER2 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

CCSER2 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 6) fully expand


Brain (Nervous System) fully expand to see all 4 entries
Cerebral Cortex

Testis (Reproductive System) fully expand to see all 3 entries
Leydig Cells Testis Interstitium
Testis Interstitium

Ovary (Reproductive System) fully expand to see all 2 entries
Ovarian Mesenchymal Stroma Cells Ovary Interstitium
Oviduct

Trophoblast (Extraembryonic Tissues)
Trophoblast Cells Trophoblast

Liver (Hepatobiliary System)
Hepatocytes Liver Lobule

CCSER2 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

CCSER2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.461988

Custom PCR Arrays for CCSER2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCSER2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CCSER2 gene from Selected species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ccser2^{1 , 5}	granule cell antiserum positive 14⁵ coiled-coil serine rich 2¹	84.4(n)¹ 82.22(a)¹		14 (21.29 cM)⁵ 72972¹ NM_027045.1¹ NP_081321.1¹ 36874936⁵
chicken (Gallus gallus)	Aves	FAM190B⁶	Gallus gallus family with sequence similarity 190,...	57(a)	1 ↔ 1	6(452392-518973)
lizard (Anolis carolinensis)	Reptilia	CCSER2⁶	coiled-coil serine-rich protein 2	57(a)	1 ↔ 1	GL343251.1(1213445-1357010)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.17140²	Transcribed sequences	76.19(n)		BX769556.1
zebrafish (Danio rerio)	Actinopterygii	CCSER2 (1 of 2)⁶ ccser2⁶	coiled-coil serine-rich protein 2	35(a) 27(a)	many → 1 many → 1	17(26319356-26379618) ENSDARG00000087749 12(14060982-14187273) ENSDARG00000091535

ENSEMBL Gene Tree for CCSER2 (if available)
TreeFam Gene Tree for CCSER2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for CCSER2 gene

CCSER2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for CCSER2
PGOHUM00000236739

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140176623^1,2	C	--	86086420(+)	`GCCTT-/CTTTTT`	1	--	us2k¹		0	--	--	--	--
rs147927591^1,2	C	--	86086595(+)	`ATTTC-/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs150262423^1,2		--	86086669(+)	`CTCCCG/TCCTCA`	1	--	us2k¹		0	--	--	--	--
rs184842273^1,2		--	86086702(+)	`CAGTCA/GTGAGC`	1	--	us2k¹		0	--	--	--	--
rs145467406^1,2		--	86086787(+)	`TGGAGC/TGCAGT`	1	--	us2k¹		0	--	--	--	--
rs188386947^1,2		--	86086824(+)	`CCACCG/TCCCAG`	1	--	us2k¹		0	--	--	--	--
rs12255083^1,2	C,F,A	--	86086860(+)	`CTCCTA/GAGTAG`	1	--	us2k¹		5		NA WA CSA	9
rs10736320^1,2	C,F,H	--	86086929(+)	`ACGGGG/ATTTCA`	1	--	us2k¹		7		NA WA CSA	15
rs137963153^1,2		--	86087024(+)	`GCCATC/TGCCTC`	1	--	us2k¹		0	--	--	--	--
rs142437889^1,2		--	86087057(+)	`ATCTCA/TCTTAA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CCSER2 (86088342 - 86278276 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for CCSER2: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing CCSER2

DNA2.0 Custom Variant and Variant Library Synthesis for CCSER2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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2 diseases for CCSER2: About MalaCards

schizophrenia alzheimer's disease

CCSER2 for disorders About GeneDecksing

Export disorders for CCSER2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CCSER2 gene, integrated from 10 sources (see all 15):
(articles sorted by number of sources associating them with CCSER2)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)^{1, 2, 3} Hirosawa M.... Ohara O. (DNA Res. 1999)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)¹ Couzens A.L....Gingras A.C. (Sci Signal 2013)
Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)¹ Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (Sci Signal 2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (Mol. Med. 2010)
Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)¹ Hutchins J.R.... Peters J.M. (Science 2010)
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)¹ Camargo L.M....Brandon N.J. (Mol. Psychiatry 2007)
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)¹ Grupe A....Goate A. (Am. J. Hum. Genet. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54462	HGNC: 29197	AceView: KIAA1128	Ensembl:ENSG00000107771	euGenes: HUgn54462
ECgene: CCSER2	H-InvDB: CCSER2

(According to HUGE)
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HUGE: KIAA1128

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CCSER2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CCSER2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CCSER2 gene:
Search GeneIP for patents involving CCSER2

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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
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	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for CCSER2
	OriGene qPCR primer pairs and template standards for CCSER2		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for CCSER2
	OriGene qSTAR qPCR primer pairs in human, mouse for CCSER2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
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	OriGene Custom Antibody Services for CCSER2		OriGene Custom Protein Services for CCSER2

	Block miRNA regulation of human, mouse, rat CCSER2 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing CCSER2
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCSER2		Predesigned siRNA for gene silencing in human, mouse, rat CCSER2
	QuantiFast Probe-based Assays in human, mouse, rat CCSER2		QuantiTect SYBR Green Assays in human, mouse, rat CCSER2
	Custom PCR Arrays for CCSER2		Search Chromatin IP Primers for CCSER2
	Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat CCSER2		Search GeneGlobe Interaction Network for CCSER2
	Search Regulatory tfbs for CCSER2

	GenScript Custom Purified and Recombinant Proteins Services for CCSER2		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CCSER2
	GenScript Custom Assay Services for CCSER2		GenScript Custom overexpressing Cell Line Services for CCSER2
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

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Search Tocris compounds for CCSER2 (CCSE2)

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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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Browse ESI BIO Cell Lines and PureStem Progenitors for CCSER2

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCSER2

	Browse SwitchGear 3'UTR luciferase reporter plasmids for CCSER2
	SwitchGear Promoter luciferase reporter plasmids for CCSER2

ThermoFisher Antibody for CCSER2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCSER2

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCSER2
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCSER2

LSBio Antibodies in human, mouse, rat for CCSER2

Customized transgenic rodents for:

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Browse compounds at ApexBio

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CCSER2 Gene

Coiled-Coil Serine-Rich Protein 2

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CCSER2 Gene

Coiled-Coil Serine-Rich Protein 2

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CCSER2 Human Recombinant Protein Products:

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for CCSER2 gene

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for CCSER2 gene

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for CCSER2 gene

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Genomic Variants
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Publications
for CCSER2 gene

Intellectual Property
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