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Aliases for CCSER2 Gene

Aliases for CCSER2 Gene

  • Coiled-Coil Serine-Rich Protein 2 2 3 4
  • KIAA1128 2 3 4
  • Family With Sequence Similarity 190, Member B 2 3
  • Protein GCAP14 Homolog 3 4
  • FAM190B 3 4
  • Serine-Rich Coiled-Coil Domain-Containing Protein 2 3
  • Protein FAM190B 3
  • BA486O22.1 3
  • Gcap14 3

External Ids for CCSER2 Gene

Previous Symbols for CCSER2 Gene

  • KIAA1128
  • FAM190B

Summaries for CCSER2 Gene

GeneCards Summary for CCSER2 Gene

CCSER2 (Coiled-Coil Serine-Rich Protein 2) is a Protein Coding gene. GO annotations related to this gene include microtubule binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCSER2 Gene

Genomics for CCSER2 Gene

Genomic Location for CCSER2 Gene

Start:
84,328,586 bp from pter
End:
84,518,521 bp from pter
Size:
189,936 bases
Orientation:
Plus strand

Genomic View for CCSER2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCSER2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCSER2 Gene

No data available for Regulatory Elements for CCSER2 Gene

Proteins for CCSER2 Gene

  • Protein details for CCSER2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7U1-CCSE2_HUMAN
    Recommended name:
    Serine-rich coiled-coil domain-containing protein 2
    Protein Accession:
    Q9H7U1
    Secondary Accessions:
    • B4DFY4
    • B4DQU9
    • B7WPE8
    • D3DWE2
    • Q8N6E9
    • Q9H2S0
    • Q9ULU1

    Protein attributes for CCSER2 Gene

    Size:
    834 amino acids
    Molecular mass:
    93548 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAG44473.1; Type=Frameshift; Positions=187, 240, 244; Evidence={ECO:0000305}; Sequence=AAH30528.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI40902.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for CCSER2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCSER2 Gene

Proteomics data for CCSER2 Gene at MOPED

Post-translational modifications for CCSER2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCSER2 Gene

No data available for DME Specific Peptides for CCSER2 Gene

Domains for CCSER2 Gene

Protein Domains for CCSER2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CCSE2_HUMAN
Family:
  • Belongs to the CCSER family.:
    • Q9H7U1
genes like me logo Genes that share domains with CCSER2: view

No data available for Gene Families for CCSER2 Gene

Function for CCSER2 Gene

Gene Ontology (GO) - Molecular Function for CCSER2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008017 microtubule binding IEA --
genes like me logo Genes that share ontologies with CCSER2: view

miRNA for CCSER2 Gene

miRTarBase miRNAs that target CCSER2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCSER2 Gene

Localization for CCSER2 Gene

Gene Ontology (GO) - Cellular Components for CCSER2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015630 microtubule cytoskeleton IEA --
genes like me logo Genes that share ontologies with CCSER2: view

Pathways for CCSER2 Gene

SuperPathways for CCSER2 Gene

No Data Available

Interacting Proteins for CCSER2 Gene

Gene Ontology (GO) - Biological Process for CCSER2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001578 microtubule bundle formation IEA --
genes like me logo Genes that share ontologies with CCSER2: view

No data available for Pathways by source for CCSER2 Gene

Transcripts for CCSER2 Gene

Unigene Clusters for CCSER2 Gene

Coiled-coil serine-rich protein 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCSER2 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d
SP1: - - -
SP2: - - - -
SP3: - -
SP4: -
SP5:

Relevant External Links for CCSER2 Gene

GeneLoc Exon Structure for
CCSER2
ECgene alternative splicing isoforms for
CCSER2

Expression for CCSER2 Gene

mRNA expression in normal human tissues for CCSER2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCSER2 Gene

SOURCE GeneReport for Unigene cluster for CCSER2 Gene Hs.461988

genes like me logo Genes that share expressions with CCSER2: view

Orthologs for CCSER2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCSER2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCSER2 37
  • 75 (a)
OneToOne
KIAA1128 36
  • 99.59 (n)
  • 99.33 (a)
cow
(Bos Taurus)
Mammalia CCSER2 37
  • 90 (a)
OneToOne
FAM190B 36
  • 90.96 (n)
  • 86.53 (a)
dog
(Canis familiaris)
Mammalia CCSER2 37
  • 27 (a)
OneToOne
FAM190B 36
  • 91.48 (n)
  • 87.37 (a)
mouse
(Mus musculus)
Mammalia Ccser2 36
  • 84.4 (n)
  • 82.22 (a)
Ccser2 16
Ccser2 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCSER2 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCSER2 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccser2 36
  • 85.2 (n)
  • 80.79 (a)
chicken
(Gallus gallus)
Aves FAM190B 37
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCSER2 37
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17140 36
zebrafish
(Danio rerio)
Actinopterygii ccser2 37
  • 27 (a)
OneToMany
CCSER2 (1 of 2) 37
  • 35 (a)
OneToMany
Species with no ortholog for CCSER2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCSER2 Gene

ENSEMBL:
Gene Tree for CCSER2 (if available)
TreeFam:
Gene Tree for CCSER2 (if available)

Paralogs for CCSER2 Gene

Pseudogenes.org Pseudogenes for CCSER2 Gene

genes like me logo Genes that share paralogs with CCSER2: view

No data available for Paralogs for CCSER2 Gene

Variants for CCSER2 Gene

Sequence variations from dbSNP and Humsavar for CCSER2 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs2960 -- 84,392,255(-) CTCCA(C/G)ATGTT intron-variant, upstream-variant-2KB
rs11915 -- 84,514,546(+) CTCCA(C/G)GTCAG utr-variant-3-prime, downstream-variant-500B
rs868090 -- 84,435,104(+) TCTCA(C/T)GGTGG intron-variant
rs868446 -- 84,435,757(-) CAATT(C/T)AGGCC intron-variant
rs970993 -- 84,472,790(-) TTCTT(A/G)TTTTT intron-variant

Relevant External Links for CCSER2 Gene

HapMap Linkage Disequilibrium report
CCSER2

No data available for Structural Variations from Database of Genomic Variants (DGV) for CCSER2 Gene

Disorders for CCSER2 Gene

No disorders were found for CCSER2 Gene.

No data available for UniProtKB/Swiss-Prot for CCSER2 Gene

Publications for CCSER2 Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3
  5. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo L.M. … Brandon N.J. (Mol. Psychiatry 2007) 3

Products for CCSER2 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CCSER2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CCSER2
    • Block miRNA regulation of CCSER2 using miScript Target Protectors

    Sources for CCSER2 Gene

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